Medicine, Human Health Technology Offers

Consejo Superior de Investigaciones Científicas posted this:

Test for oral tolerance to triglycerides in humans The Instituto de la Grasa of CSIC and University of Seville have developed a fast and simple procedure to evaluate the tolerance to dietary fats (triglycerides) in humans. A novel emulsified composition, easy to take and digest, is supplied to patients, and then the peak of triglycerides in blood and their clearance are determine in a short period of 4 hours. Companies interested in exploiting this technology under a patent license are sought. An offer for patent licensing

Consejo Superior de Investigaciones Científicas posted this:

Oleuropein obtaining procedure: high purity antioxidant CSIC has developed a reliable and effective method for obtaining oleuropein from olive leaf: comprising a pretreatment that increases the concentration of oleuropein in the extracts over other known methods and achieving this bioactive compound with a purity superior of 70%. Industrial partners from the food and pharmaceutical industry are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing

Consejo Superior de Investigaciones Científicas posted this:

Modulating compounds of KChIP2 and its use for the treatment of cardiovascular ppaatthhoollooggiieess CSIC and UAM have developed compounds that positively modulate protein-protein interactions that involve KChIP2 protein. Industrial partners from the pharmaceutical industry are being sought to collaborate through a patent licence agreement An offer for Patent Licensing

Consejo Superior de Investigaciones Científicas posted this:

OPTOBIOTICS: Novel antibacterial proteins activated by blue light CSIC has developed a chimeric protein that, when expressed in bacteria, changes its structure upon absorption of blue light, thus generating protein aggregates (amyloids) that inhibit bacterial growth Industrial partners from the pharmaceutical industry are being sought to collaborate through a patent licence agreement An offer for Patent Licensing

Consejo Superior de Investigaciones Científicas posted this:

Continuous indoor rearing of Philaenus spumarius, the main European vector of Xylella fastidiosa CSIC has developed a methodology to rear the meadow spittlebug Philaenus spumarius (L.) (Hemiptera, Aphrophoridae) in control climatic conditions in the laboratory allowing the supply of nymphs and adults before they become available in the field. This continuous indoor-rearing protocol could facilitate studies on the biology, ecology and management of P. spumarius and on the transmission of Xylella fastidiosa. Innovative and research partners from the agro sector are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing

Consejo Superior de Investigaciones Científicas posted this:

Production of high-affinity antibodies through the in vitro recreation of a germinal center CSIC have developed a method for the in vitro generation of antigen-specific antibodies or cells producing thereof by means of the development of an in vitro germinal center useful to produce vaccines, immunomodulators or immunotherapies. Industrial partners from the biotechnology and/or pharmaceutical industry are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing

Consejo Superior de Investigaciones Científicas posted this:

Particle identification using a high precision system based on multi-frequency measurements of resonant plates CSIC has developed a new system that allows to identify and classify nanometric and micrometric particles. This system is based on the changes produced at different resonance frequencies of thin plate type structures when these particles are adsorbed onto their surface. This technology represents an important achievement in the field of nanomechanical spectrometry and is suitable for the identification and classification of viruses, bacteria or proteins. Industrial partners manufacturers of lab equipment are being sought to collaborate through a patent license agreement. An offer for Patent Licensing

Consejo Superior de Investigaciones Científicas posted this:

Identification of particles and/or cells in suspension using a mechano-optical system CSIC has developed a sample analyzing system that can identify particles and/or biological cells in aqueous suspension or in physiological medium. The system allows simultaneously measuring the mass and light scattering of the particles in suspension in real time. This technology has been used to distinguish different cell lines, making it useful for diagnosing diseases. Industrial partners manufacturers of lab equipment are sought to collaborate through a patent license agreement. An offer for Patent Licensing

Consejo Superior de Investigaciones Científicas posted this:

Biocompatible self-generating cell stimulator CSIC through the Instituto de Microelectrónica de Barcelona - Centro Nacional de Microelectrónica,has developed a device based on nanogenerators for electrical cells stimulation without the need of electrodes or bulky devices. The device is biocompatible and, among its multiple applications, is able to actuate in medical prostheses as enhancer of cellular growth and proliferation, which permits an early lesion recovery (such as a fracture or wound). Industrial partners dedicated to the development of medical devices for cells stimulation, in particular, focused onto therapeutic treatments of non-healing wounds, are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing

Yissum - Research Development Company of the Hebrew University posted this:

Naturally Occurring Compounds for Treating Pathogenic Factors Common to Cystic Fibrosis Cannabis project Derivatives of cannabinoids have an antimicrobial and anti biofilm effect on pseudomonas and candida which are major ethological pathogenic factors in CF Project ID : 6-2019-6720

Yissum - Research Development Company of the Hebrew University posted this:

Platform for Neutrophil Specific Targeting as a Mode of Immunotherapy Dr. Zvika Granot, from the School of Medicine-IMRIC-Developmental Biology and Cancer Research, is working on a innovative approach for Neutrophil specific targeting of TGF-beta signaling as a novel anti-cancer therapy (see attached summary and several papers) Project ID : 6-2015-4241

Yissum - Research Development Company of the Hebrew University posted this:

Personalized Phage Therapy: A New Paradigm for Combating Infectious Disease in the Age of Antibiotic Resistance A New Paradigm for Combating Infectious Disease in the Age of Antibiotic Resistance. Phage Therapy offers significant advantages: 1) Natural- Harnessing nature’s own enemy against bacteria 2) Smart kinetics Phages grow with bacteria and disappear in its absence 3) Can be manipulated (unlike antibiotics) Engineered / evolutionary developed 4) Efficient against biofilm Chain reaction of the phages 5) Do not harm the microbiome Highly specific to the target pathogen. Hazan's approach for a Personalized Phage Therapy suggests an adaptive and dynamic cocktail of phages and antibiotics , that are specially tailored using AI and machine learning prediction. Hazan et.al. offer a constantly increasing “Bank” of phages. Project ID : 43-2019-10746

Yissum - Research Development Company of the Hebrew University posted this:

Novel Drug Delivery System of Large Molecules for Localized Sustained Release Novel Drug Delivery System of Large Molecules for Localized Sustained Release Project ID : 6-2018-4643

Yissum - Research Development Company of the Hebrew University posted this:

Novel Chimeric System for Targeted Killing of Lymphocytic Cancer Cells Novel Chimeric Protein utilizing components of the Ubiquitin-Proteasome System for targeted killing of Lymphocytic Cancer Cells Project ID : 6-2018-4687

Yissum - Research Development Company of the Hebrew University posted this:

New Methodology to Control Calcium Carbonate Morphology and Material State New Methodology to Control Calcium Carbonate Morphology and Material State Project ID : 6-2018-4599

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