Medicine, Human Health Technology Offers

Biótica, Bioquímica Analítica,S.L. posted this:

ULISENS Legionella Desktop Analyzer Fully automated equipment for 1 hour-determination of Legionella in concentrated water samples. The #ULISENS Desktop is a portable computer that makes it possible to analyze #Legionella in filtered water samples. With the "nespresso" philosophy, it uses a recyclable cartridge. "Push & Run" and the data is available in only 1 hour. It automates the rapid immunomagnetic method listed in the norm UNE100030:2017 for the control and prevention of #Legionella. (https://youtu.be/baiHP26xwCs)

Consejo Superior de Investigaciones Científicas posted this:

In vitro method for designing a customized therapy for a subject with Parkinson´s Disease CSIC, Université de Lille, INSERM and Centre Hospitalier Regional Universitaire de Lille have developed an in vitro method for designing a customized therapy for a Parkinson ‘s Disease patient through the determination of the presence of a centrosomal deficit from that subject and therefore susceptible to receive a therapy based on a LRRK2 inhibitor. LRRK2 is a key player for the development of both genetic and sporadic forms of Parkinson’s Disease (PD). Industrial partners from pharmaceutical industry are being sought to collaborate through a patent licence agreement.

Yissum - Research Development Company of the Hebrew University posted this:

Diagnosis & Rehabilitation of Language Disorders in Children, Using a Self-Operated Tablet Based App Diagnosis & Rehabilitation of Language Disorders in Children, Using a Self-Operated Tablet Based App Project ID : 19-2019-8746

Yissum - Research Development Company of the Hebrew University posted this:

Enhanced Secretion of Proteins by Tag-Cleaving Cellular System Enhanced Secretion of Proteins by Tag-Cleaving Cellular System Project ID : 6-2019-8747

Ivan Rodriguez Rosello posted this:
Licensing Manager at Universidad de Alicante

Antibacterial alternative to antibiotics, with high specificity against Escherichia coli The "Molecular Microbiology" research group at the University of Alicante has modified several phage proteins (Poll-N and UK-C) that have high specificity against Escherichia coli (E. coli), but not against other Gram-negative (G-) bacteria. For these reasons, their use as a specific antimicrobial against E. coli is potentially interesting, especially in the case of contaminated food, cosmetics or water. It would also be useful in the treatment of diseases (infections) caused by E. coli. The presence of a histidine tail attached to the phage proteins not only facilitates their purification but also improves lysis efficiency without the need of cell permeabilization treatments. Companies interested in the commercial exploitation of the technology through license agreements and/or technical cooperation are sought.

University of Vigo posted this:

Procedure for the extraction of biosurfactants contained in corn steep liquors Nowadays, most of the pharmaceutical and cosmetic products in the market contain chemically synthesized surfactants in its composition. In many cases, these surfactants are the same as those used in regular cleanup activities. In order to get more natural and biocompatible products, it would be interesting to include natural surfactants instead of chemical surfactants in the preparation of these pharmaceutical and cosmetic products. These biosurfactants are also present in the formulation of greener nanoparticles, replacing the chemical surfactants currently used in the preparation thereof. Most biosurfactants have antimicrobial activity, which would improve the properties of certain nanoparticles, as well as many pharmaceutical and cosmetic products. The main disadvantage of biosurfactants industrial production is related to the high cost compared to chemically synthesized surfactant production. The solution proposed by the Chemical Engineering research group at the University of Vigo, is the development of eco-friendly simple extraction of biosurfactant from a corn wet-milling industry byproduct, such as corn wash liquors, better known as "corn steep liquor (CSL)", which could compete in terms of cost production with its chemical counterparts.

National Cancer Institute CRO Aviano posted this:

HPLC device for high-volume samples analysis Fluidic device that allows high sample volume injection in HPLC systems and provides an automated purification step, reducing sensitivity problems and facilitating the analysis of extracted compounds from complex matrix.

National Cancer Institute CRO Aviano posted this:

CHEMIOTHERAPY: IMATINIB DRUG MONITORING The effectiveness of many anticancer drugs varies greatly from patient to patient, with risks of incorrect dosages and adverse side effects. The invention provides for the first time an electrochemical method to measure the concentration of the drug Imatinib in patient's plasma and then to establish the optimal dose, with an on site test readable in real time.

National Cancer Institute CRO Aviano posted this:

Mechanisms of p53 inactivation in TP53 wild type tumors and factors affecting sensitivity to MDM2 inhibitors The research group led by Dr Roberta Maestro demonstrated that the overexpression of the protein Twist, detectable in a large fraction of sarcomas but also in a fraction of carcinomas, facilitates the MDM2-mediated degradation of p53 by making p53 more susceptible to MDM2 attack. The p53:MDM2 interplay is the target of a number of compounds currently under clinical trials. These compounds (MDM2i) are aimed at alleviating p53 from MDM2-mediated degradation and hence at restoring the p53 tumor suppressive activity. Maestro and coworkers gathered data indicating that the expression of Twist may significantly impact on the activity of these drugs.

LUCIA CORAL posted this:
Knowledge Tranfer Manager at National Cancer Institute CRO Aviano

Predictive Kit to identify patients non responding to platinum therapy Predictive Kit to identify patients non responding to platinum therapy. 10 gene signature as a predictive biomarker for platinum treatment against different cancer types. The invention consists in quantifying the expression of 10 genes from tumor cells to detect patients eligible for platinum treatment at higher risk of developing drug resistance and disease progression. Drugs such as cisplatin, oxaliplatin and carboplatin are used to treat various types of worldwide common cancer, but resistance is a frequent event. Patient stratification based on tumor gene expression profile allows to personalize treatment reducing side effects and costs.

University of Granada (OTRI) posted this:

Method for diagnosing Hereditary Hemorrhagic Telangiectasia (HHT)Hereditary Hemorrhagic Telangiectasia (HHT) is a rare and genetic disease in which a disorder in angiogenesis exists. A new method for the molecular diagnosis of this disease has been developed. It is based on the quantification of a set of microRNAs (miRNAs) transported by plasma exosomes, and in addition, this set allows diagnosing different variants of the disease. This new method has the advantage of providing new biomarkers that allow a rapid and reliable diagnosis of HHT, since the current methods are not valid for all the patients affected with HHT.

UACOOPERA University of Aveiro posted this:
Technology Transfer Office at uacoopera

MAGNETIC NANOPARTICLES FOR TEMPERATURE-CONTROLED MOLECULE AND CELL SEPARATION AND DETECTION Coated and functionalized magnetic nanoparticles for e.g. detection and separation of DNA and RNA, protein purification, cell separation and immunoassays, con-trolled by temperature. Contrary to state-of-art mag-netic nanoparticles presently used for separation, which always present a certain degree of aggregation, the present technology proposes nanoparticles with tem-perature-controlled magnetic response. The magnetic response of these new nanoparticles is suppressed at higher temperatures (tunable between 40°C and 100°C) avoiding aggregation and is enhanced at lower temperatures promoting separation.

UACOOPERA University of Aveiro posted this:
Technology Transfer Office at uacoopera

Immunoglobulin Y Purification, Its Products And Uses This invention describes a purification process of immunoglobulin Y from egg yolk in three stages, by applying precipitation methods, liquid-liquid extraction and ultracentrifugation. The present process allows to obtain immunoglobulin Y of high quality and with a purity >95%, in a simple and economic way, and applicable at an industrial scale.

Universidad de Alcalá-OTRI posted this:

Emotongue: A software for every customer with a Smartphone (Android) interested in managing their own emotions and for companies interested in their employees’ emotional health SUMMARY Emotongue is an application for smartphones with the Android System, designed in Spanish and English, so that every customer who speaks one or both of them could easily use it every time and everywhere, having a data connection. Emotongue is not a simple app, it is the app that everybody was looking for! It had been designed for a research project carried out in the Department of Sciences of Education of the University of Alcalá, Spain, but due to its features and the great benefits it has, now it is available for every customer interested in improving his/her resources for managing his/her emotional world. Emotongue has been created for helping people to know their emotions, connect with them and learn how to manage them. The app is a tool easy to use, with a colored and dynamic design. It sends the user 5 notifications per day, and she/he has at his/her disposal 2 hours to answer each notification either by a written message or by an audio. The app is available in every country in which people speak English and/or Spanish. An improved version of the app could send users a feedback about their evolution in their management of their emotions and their use of the app. A part from the app, the authors could offer a service to companies interested in it, by creating courses about emotional management, designed according to the company’s needs, something very difficult to find in the trade market.

Consejo Superior de Investigaciones Científicas posted this:

Immunoassay for rapid diagnosis of infectious diseases caused by Pseudomonas aeruginosa CSIC, CIBER-BBN and UAB have developed an immunochemical method for diagnosis of infections produced by Pseudomonas aeruginosa. The immunoassay is fast and efficient, with low LOD and adaptable to point-of care devices.

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