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Unitat de Valorització de la URV posted this:
Licensing Manager at Fundació URV

New method for the diagnosis of diseases caused by helminths Cystic Echinococcosis, also known as hydatid disease (Hydatidosis), is a parasitic disease caused by the tapeworms of genus Echinococcus. Hydatidosis is globally distributed and found in every continent except Antarctica. Endemic areas are parts of Argentina, Peru, East Africa, Central Asia and China. The infection to humans occur through the ingestion of parasite eggs in contaminated water, food, soil or through direct contact with animal hosts such as dogs and sheep. Human infection with E. granulosus leads to the development of one or more hydatid cysts located most often in the liver and lungs, and less frequently in the bones, kidneys, spleen, muscles, central nervous system and eyes. The asymptomatic incubation period of the disease can last many years until hydatid cysts grow to an extent that triggers clinical signs. The diagnosis is done through ultrasonography imaging, which is usually complemented or validated by computed tomography and/or magnetic resonance imaging scans. Cysts can be incidentally discovered by radiography. Specific antibodies are detected by different serological tests and can support the diagnosis. Biopsies and ultrasound-guided punctures may also be performed for differential diagnosis of cysts from tumours and abscesses. In this invention, a new system for non-invasive, early, fast and easy to use diagnosis test for Hydatidosis from exhaled breath analysis has been developed.

New method for the diagnosis of diseases caused by helminths

Maria João Cardoso posted this:
Science and Technology Manager at UATEC - Unidade de Transferência de Tecnologia

Magnetic nanoparticles for selective enrichment of proteins in complex mixtures New method for preparing ion chelating magnetic nanoparticles, which allow selective protein enrichment, namely metalloproteases (MMPs) and His-tagged proteins, from complex mixtures.

Magnetic nanoparticles for selective enrichment of proteins in complex mixtures

Krasen Dimitrov posted this:
CEO at MAMEL&Ecobiotechnoservice

New effective and eco-friendly product to destroy Helicobacter pylori on the basis of plant components to which the bacteria can not become resistant.The product prevents stomach cancer, stomach ulcer, chronic gastritis, duodenal cancers and can al The product prevents stomach cancer, stomach ulcer, chronic gastritis, duodenal cancers and can also be used by healthy people without symptoms. It does not contain antibiotics! Absolutely harmless to all organs of the body - does not cause complications! Extremely effective against the destruction of Helicobacter pylori. Unlike known forms of antibiotic and probiotic treatment, the product offers an alternative through specially selected plant extracts processed in an established plant to increase the natural antibacterial properties in a way that the bacteria can not get resistance.

New effective and eco-friendly product to destroy Helicobacter pylori on the basis of plant components to which the bacteria can not become resistant.The product prevents stomach cancer, stomach ulcer, chronic gastritis, duodenal cancers and can al

Universidad de Alcalá-OTRI posted this:

Compounds for the treatment of Leishmania infections The research group Heterobetainas of the University of Alcalá presents the preparation and uses of a series of compounds that act as bioactive agents against the Leishmania parasite and as therapeutic agents in the treatment of this disease, in both, its visceral (LV) version and in the mucocutaneous one (CML). The group is looking for pharmaceutical companies interested in manufacturing an active ingredient for the formulation of a leishmanicidal drug based on these compounds. The group proposes the signing of a patent license agreement, a collaboration agreement or a commercial agreement with technical

Compounds for the treatment of Leishmania infections

Mahesh Kulkarni posted this:
Business Development Manager at Praj Industries Limited

Tocopherol or Vitamin E from Soyabean Oil Distillate Unique proprietary technology to produce high purity mixture of fatty acids and tocopherol enriched fractions. Process suitably uses feedstock like soyabean, sunflower and cotton seed DOD. Higher Tocopherol recovery. Payback 2.5-3.0 years.

Universidad de Alcalá-OTRI posted this:

Endothelial microvesicles with microbicidal effect for the preparation of a medicament or for a direct use The research group "Cell damage associated with senescence" of the University of Alcalá presents the microbicidal capacity of endothelial microvesicles. These vesicles destroy the main pathogens involved in sepsis and even strains derived from them resistant to multiple antibiotics. They have also been shown to be effective against the biofilms that form these microorganisms. The group seeks to reach licensing agreements, cooperation or commercial agreements with technical assistance, with pharmaceutical companies interested in the design of new medicines.

Endothelial microvesicles with microbicidal effect for the preparation of a medicament or for a direct use

Núria Brunet i Garcia posted this:
Licensing Manager at Universitat de Lleida

New therapeutic candidate for Spinal Muscular Atrophy We are looking for a licensing agreement with a company with expertise in the field of neurosciences. More particularly, we are willing to find a company involved in the development of therapeutic solutions for the rare disease Spinal Muscular Atrophy (SMA).

Maria João Cardoso posted this:
Science and Technology Manager at UATEC - Unidade de Transferência de Tecnologia

Innovative methodology for nanoencapsulation of montelukast in cyclodextrin Cyclodextrin is a nano-sized capsule that allows increasing the stability and aqueous solubility of active pharmaceutical ingredients such as montelukast. This technology comprehends an alternative method to obtain an amorphous solid composed by montelukast and cyclodextrin. In alternative to conventional methodologies, this method allows the encapsulation to occur without requiring the use of solvents and the formation of degradation products.

Innovative methodology for nanoencapsulation of montelukast in cyclodextrin

Maria João Cardoso posted this:
Science and Technology Manager at UATEC - Unidade de Transferência de Tecnologia

Separation of nucleic acids using chromatographic matrices functionalized with ionic liquids Novel multimodal chromatographic supports prepared by functionalizing matrices with ionic liquids, allowing the separation of RNA and DNA in a single chromatographic step with high selectivity, robustness and reproducibility. In comparison to other commercially available supports, a higher dynamic binding capacity for RNA was obtained.

Separation of nucleic acids using chromatographic matrices functionalized with ionic liquids

UNIVERSIDAD DE BURGOS posted this:

Method of preparation and use of derivatives of perylene-diimide (PDI) in different applications such as bioimaging or biomarkers.The present invention provides a methodology for the synthesis of derivatives of perylene-diimide (PDI, for which there was no obtention process, and its use in different applications such as bioimaging or biomarkers.

Method of preparation and use of derivatives of perylene-diimide (PDI) in different applications such as bioimaging or biomarkers.

Yissum - Research Development Company of the Hebrew University posted this:

A novel target for the treatment of genetic diseases caused by nonsense mutations A novel target for the treatment of genetic diseases caused by nonsense mutations Project ID : 6-2018-4579

Lucas Montes posted this:
Technology Transfer Advisor at University of Granada (OTRI)

Biomimetic magnetic nanoparticles for its use in biotechnological applications The present invention provides a composition which contains nanoparticles of magnetite made in presence of magnetosome proteins expressed as recombinant. These nanoparticles are biocompatibles, have a negative charge at physiological pH and a size higher tan 30nm, considered in the range of the singular magnetic domain, for different uses in the field of biotechnology, as well as for its use for for drug administration for the treatment of cancer.

Universidad de Granada posted this:

Method for isolating circulating epithelial pulmonary cells and their use as markers for diagnosing Chronic Obstructive Pulmonary Disease (COPD)A procedure is described based on Liquid Biopsy techniques that allows both the diagnosis of COPD, as well as its evolution in patients. In order to do that, circulating pulmonary cells (CPCs) that could be present in blood of patients diagnosed with COPD are detected and characterized by combining two different techniques: - Immunogenetic positive selection for their isolation in peripheral blood. - Immunocytochemistry for detecting CPCs by using specific markers for pulmonary epithelial cells.

Method for isolating circulating epithelial pulmonary cells and their use as markers for diagnosing Chronic Obstructive Pulmonary Disease (COPD)

Russell Nicholls posted this:
Licensing Manager at Curtin University

Rhenium compounds as anticancer agents Metal-based anticancer agents, such as cisplatin, are used as gold standard cancer therapies. While these drugs are effective in eradicating malignant cells, their selectivity is poor, meaning that significant adverse effects are experienced during treatment through damage inflicted on healthy cells. Improved selectivity and targeted cancer therapies with minimal side effects are being sought. Many drugs have been developed which contain platinum, and other metals are now being developed as anticancer agents. Researchers at Curtin University developed a series of rhenium containing compounds that target cancerous cells and block their growth. These compounds are promising candidates for treatment of tumours with aggressive potential for metastasis (for example, pancreatic cancer). A library of molecular candidates have been synthesized, and structure-activity relationship to modulate selectivity and therapeutic potential has been explored.

Yissum - Research Development Company of the Hebrew University posted this:

Novel Indoline Derivatives as Anti-Inflammatory Agents for the Treatment of Diabetes Novel Indoline Derivatives as Anti-Inflammatory Agents for the Treatment of Diabetes Project ID : 7-2015-3171

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