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Universidad de Granada posted this:

Compounds for the treatment of Leishmaniasis and other diseases caused by trypanosomes.Several compounds have been synthesized that are useful for the treatment of Leishmaniasis and other diseases caused by parasites of the Trypanosomatidae family. These compounds show an improvement in the antiparasitic activity and reduced toxicity compared to the usual commercial treatments, causing damage to the key enzyme in the survival of the parasite without significantly affecting that of the human host. Therefore, they are a potential alternative to current treatments used to fight against Leishmaniasis or Chagas disease.

Compounds for the treatment of Leishmaniasis and other diseases caused by trypanosomes.

Vilnius University posted this:

Technology for Contactless Dosimetry / Fluxmetry of Ionising Radiations Vilnius University offers a contactless and in situ continuous dosimetry / fluxmetry system for ionizing radiation detection. A single device measures a very wide range or radiation and is suitable for large area radiation control in radiation research centres, nuclear energy related facilities and specific medical purposes.

Technology for Contactless Dosimetry / Fluxmetry of Ionising Radiations

CNIC (TTO) posted this:
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)

New method for the diagnosis of atherosclerosis Inflammation is an active driver of atherosclerotic plaque development and a risk factor for atherosclerotic events. It is therefore of utmost importance to understand the mechanisms behind these inflammatory processes and to be able to develop new diagnostics and treatment modalities for atherosclerotic disorders. CNIC, FJD (Fundación Jiménez Díaz) and UAM (Universidad Autónoma de Madrid) researchers conducted a study to identify new antibodies that show reactivity against the atherosclerotic plaque. They have found that one of these antibodies recognizes a mitochondrial dehydrogenase of the proline metabolism (PRODH). The levels of this protein are increased in the plasma of atherosclerotic mice and humans with carotid disease, supporting the potential use of this PRODH as a biomarker for atherosclerosis.

Fabiola Moreno posted this:
Technology Licensing Assistant at Binghamton University

Novel Therapeutic Agent to Target Microbial Biofilms A naturally produced signaling molecule combats chronic and resistant hard-to-treat infections and contaminations by inducing microbial biofilms to disperse.

Novel Therapeutic Agent to Target Microbial Biofilms

Fabiola Moreno posted this:
Technology Licensing Assistant at Binghamton University

Treatment of L-DOPA-induced Dyskinesia in Parkinson’s Disease Repurposed antidepressant agents for treating levodopa-induced dyskinesia (LID) in Parkinson's disease dramatically reduced LID and maintained these effects for several weeks without altering L-DOPA’s positive anti-parkinsonian effects.

Treatment of L-DOPA-induced Dyskinesia in Parkinson’s Disease

Yissum - Research Development Company of the Hebrew University posted this:

Novel Blood Test for Early Detection of Alzheimer’s Disease Non-Invasive Detection of Brain Cell Death Using Methylation Patterns of Circulating DNA: A Novel Blood Test for Early Detection of Alzheimer’s Disease Project ID : 47-2020-10832

Covid-19 Innovation Challenges by Innoget posted this:

SARS-CoV-2 Targeted Libraries for offer Protease-Oriented SARS-CoV-2 Library (1017 Compounds) - Developed by Virtual Receptor-Based Screening Using the Crystal Structure of the Basic SARS-CoV-2 Protease (PDB ID: 6LU7) ML (Machine Learning) SARS-target library (1577 compounds) - carefully developed using machine learning (artificial neural networks and Bayesian statistics).

SARS-CoV-2 Targeted Libraries for offer

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

SARS-CoV-2 Targeted Libraries for offer Protease-Oriented SARS-CoV-2 Library (1017 Compounds) - Developed by Virtual Receptor-Based Screening Using the Crystal Structure of the Basic SARS-CoV-2 Protease (PDB ID: 6LU7) ML (Machine Learning) SARS-target library (1577 compounds) - carefully developed using machine learning (artificial neural networks and Bayesian statistics).

SARS-CoV-2 Targeted Libraries for offer

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

Cathepsin K Targeted Library for offer We offer the Cathepsin K Targeted Library. It contains 761 compounds with predicted inhibitory activity against this protease and suitable for the early stage of drug discovery

Cathepsin K Targeted Library for offer

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

Catechol O‑Methyl Transferase Targeted Library OTAVAchemicals offers Catechol O‑Methyl Transferase (COMT) Targeted Library. It contains 504 compounds with predicted inhibitory activity against this enzyme. The library has been carefully designed with combination of ligand- and receptor-based pharmacophore modeling.

Catechol O‑Methyl Transferase Targeted Library

Leading Biology posted this:

Yeast Expression System Service Advantages of yeast expression system service in Leading Biology 1. Having a complete Pichia pastoris expression platform could design different experimental schemes according to customers requirements. 2. Having a high throughput screening platform could find the best expression conditions quickly and effectively. 3. Could do large-scale fermentation production.

Yeast Expression System Service

Covid-19 Innovation Challenges by Innoget posted this:

Viral RNA-dependent RNA Polymerases Viral RNA-dependent RNA Polymerases (RdRPs) Targeted Library (1259 compounds) with predicted activity against viral RdRPs is offered. It has been carefully designed using machine learning (artificial neural networks and Bayesian statistics

Viral RNA-dependent RNA Polymerases

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

Viral RNA-dependent RNA Polymerases Viral RNA-dependent RNA Polymerases (RdRPs) Targeted Library (1259 compounds) with predicted activity against viral RdRPs is offered. It has been carefully designed using machine learning (artificial neural networks and Bayesian statistics

Viral RNA-dependent RNA Polymerases

Covid-19 Innovation Challenges by Innoget posted this:

SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library OtavaResearch Institute group presents SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library (1031 in-stock compounds with predicted activity against SARSCoV2 (RdRpp)).

SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library OtavaResearch Institute group presents SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library (1031 in-stock compounds with predicted activity against SARSCoV2 (RdRpp)).

SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library

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