Center for Technology Transfer and Commercialization of Novosibirsk State University posted this:Technology and equipment for production of ultra-high-molecular-weight polyethylene for medical, structural and energy applicationsThe innovative company (Russia) that cooperates with the university and R&D institutes has developed an UHMWPE production technology (ultra-high-molecular-weight polyethylene) for production of high-strength materials and threads to manufacture implants, porous filters, ropes, armor and materials for aircrafts and ships. The technology is easy to use, products are inexpensive. The company is looking for partners to find market applications for powder and fibers and to license industrial technology.
Center for Technology Transfer and Commercialization of Novosibirsk State University posted this:Preparation of Microscope Slides for medical, biological and veterinary purposesIn a laboratory of Virology and Morphology of an Academic University (Novosibirsk, Russia) the technology of production of high-quality microscope slides for histologic researches was developed. The technology can be applied in educational purposes as well as in different research programs in Pharmacology, Medicine, Biology, etc. The authors are looking for potential partners in order to hand over the technology and/or establish joint production and market implementation of biological exemplars.
Universidad de Alcalá-OTRI posted this:Development and method of construction of a new electrochemical sensor of Magnesium (Mg2 +), without the need to add organic salts, additives or organic solvents to the sampleThe research group in Bioelectrochemistry and Biosensors of the University of Alcalá in collaboration with the Textile Industry Research Association (AITEX) has developed an electrochemical sensor of magnesium (Mg2 +) and a construction method based on the formation of a polymeric three-dimensional network that allows the entrapment / immobilization of a selective indicator for Mg2 +, eriochrome black T, by the use of a crosslinking agent and a polymer. The combination of these three reagents allows the construction of the sensor on any conductive surface, avoiding the electro polymerization of the indicator. The resulting sensor allows to measure MG2 + in any type of samples, without the need to add organic salts, additives or organic solvents. The quantification of Mg2 + is done directly by incubating the sensor in the sample containing the analyte, resulting in a modification of the amperometric signal proportional to its concentration. This method has many applications especially in health and biomedical sector since Mg2 + participates in such important activities as neuronal, neuromuscular transmission, or regulation of blood pressure and plays a key role in various pathologies such as vascular and migraines headache. The group is looking for companies in the agro-food, bio-sanitary and environmental sectors, with the aim of reaching technical collaboration agreements, commercial agreements or patent licenses.
Universidad de Alcalá-OTRI posted this:Carbosilane dendrimers with a polyphenolic nucleus and their use as antiviralsThe research group in «Dendrimers for biomedical applications» of the University of Alcalá presents carbosilane dendrimers with a polyphenolic nucleus, its obtaining procedure and its uses as antiviral, antibacterial and antifungal agents. The group seeks to reach collaboration agreements, licensing or commercial agreements with technical assistance, with companies from the biotechnology, pharmaceutical and biomedicine sectors in general.
Universidad de Alcalá-OTRI posted this:Carbosilane dendrimers and their use as antiviralsThe research group in "Dendrimers for Biomedical Applications" of the University of Alcalá presents these highly branched macromolecules synthesized from a polyfunctional nucleus, of carbosilane structure and functionalized in its periphery with anionic groups that give the macromolecule a negative net charge. In addition, the invention relates to the use of the dendrimers as an antimicrobial and the process for obtaining them. The group seeks to reach collaboration agreements, licensing or commercial agreements with technical assistance, with companies in the biotechnology, pharmaceutical and biomedicine sectors in general.
Merck KGaA posted this:Technology for Lysophosphatidic Acid (LPA) Receptor antagonistsMerck has developed and patented the results of its intense R&D activities for the identification of small organic molecules as antagonists to certain LPA receptors (LPAR1, -R2, -R3). Herein described are LPA-R2 receptor selective inhibitors. Based upon a rational screening cascade established, compounds have been identified and characterized with regard to their specific in vitro and cellular activities. The package includes access to the IP, experimental results, and materials. Merck offers the unique chance to acquire this promising program.
Merck KGaA posted this:Novel Pharmaceutical Salt Forming Counterions with Increased Dissolution Rates and SupersaturationOne of the major obstacles in developing promising New Chemical Entities (NCEs) as Active Pharmaceutical Ingredients (APIs) is their low solubility and therefore poor bioavailability. Merck has developed a novel class of salt forming anions as counter-ions for protonated free base APIs which result in an accelerated dissolution rate and increased solubility by supersaturation of the NCE. The invention is based on a systematic thermodynamic and molecular engineering approach to design the above mentioned anions resulting in crystal lattices of API salts with weak Coulomb interactions.
Merck KGaA posted this:Technology for Serum and Glucocorticoid regulated kinase (SGK) inhibitorsMerck KGaA, Darmstadt, Germany, has developed and patented the results of its intense R&D activities for the identification of small organic molecules as SGK1 inhibitors. Based upon a rational screening cascade established, compounds have been identified and characterized with regard to their specific in vitro, cellular and in vivo activities. The package includes access to the IP, experimental results, and materials. Merck KGaA, Darmstadt, Germany, offers the unique chance to acquire this promising program.
Alphanosos posted this:Anti pyoderma solution in spray (veterinary)We are licensing our anti-staphylococci herbal mix extract (patent pending) with a great safety profile for veterinary use as anti-pyoderma spray (or other formulation). Successful animal model results are available. Available as API or finished product ( in preparation, Q2/2018 ).
Small and Medium Enterprise
Creative Animodel posted this:CAR-T Preclinical in vivo StudyCreative Animodel provides customized preclinical testing services for your CAR-T cells. In cooperation with our CAR-T cells production division, Creative Biolabs, we are able to provide you with one-stop full service of both CAR-T production and preclinical testing. We also offer services for customized CAR-T cell toxicity management assessments.
Small and Medium Enterprise
Hygea Salud y Nutrición posted this:Nutritional software which makes automatically personalized diets.Vitadieta is a system of Medical Nutrition Therapy, which makes automatically personalized diets for a wide range of goals (lose weight, healthy diet, sports nutrition, pathologies...). The system could be integrate inside a third-party software, or works online. Vitadieta offers functionalities of cross-selling oriented to franchises, recomending product and services of each franchise with the diets.
Universidad de Alcalá-OTRI posted this:Method of diagnosis of non-invasive renal failure and prior to symptoms and functional disordersThe Renal Nephropathy research group at the University of Alcalá presents a method of diagnosis of Renal Insufficiency (RI), in all varieties of the disease, that determines the amount of protein related to parathyroid hormone (PTHrP) present in a sample of urine, comparing said amount with at least one reference value and diagnosing RI from said comparison. The research group seeks companies from the diagnostic medicine, biomedicine or pharmacy sector to establish licensing agreements, collaboration agreements or commercial agreements with technical assistance.
Cracow University of Technology posted this:SOLVENT-FREE METHOD FOR OBTAINING API UNDER MICROWAVE IRRADIATION (TRAZODONE, ARIPIPRAZOLE, ET AL.)The developed solvent-free technology allows API synthesis under microwave irradiation with high purity and efficiency in a very short time. Its advantages include the absence of toxic solvents, an easy way to isolate products from the reaction mixture, significantly reduce the amount of additional technological operations, reduce production costs and increase work safety. The technology can be used on an industrial scale.
Cracow University of Technology posted this:The new lupeol derivative and the method of obtaining.This invention relates to a biologically active compound, the derivative of natural triterpene lupeol. This derivative is active for human skin cells, improving their proliferation process. In addition, the substance has the ability to neutralize free radicals. The described derivative can be used as an active ingredient in pharmaceutical and cosmetic preparations dedicated for damaged or burned skin, as well as in anti-aging cosmetics.