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Laijo Jose posted this:
Manager-Tech Transfer at Centre For Future (CFF)

An advanced and cost effective bioresorbable, biocompatible polymer composite for bone soft tissue fixation has been developed, and their use in preparing different orthopedic devices that serves the purpose of fixation of soft tissue injuries and low-load bearing bone fractures. The use of the given bioresorbable polymer composite in orthopedic devices is an attempt to replace the traditional metallic implants and making it accessible to masses at affordable prices, and therefore overcome the limitations of currently available bioresorbable orthopedic devices in the market. The technology produces a novel bioresorbable, biocompatible polymer composite for bone soft tissue fixation. The polymer composite biomaterial is composed of bioresorbable polymer such as poly-ε-caprolactone (PCL), natural fiber silk fibroin and an osteoconductive component like Magnesium oxide (MgO) in nanoparticle form and it can be used to prepare different orthopedic devices. The silk fiber of 20% and MgO nanoparticles in concentration of 10% were mixed together with PCL as base polymer in twin-screw extruder to produce composite orthopedic biomaterial. The newly developed bone screw is having a design with screw head shape, thread-tip design, thread profile and volume. It is found that millions of screws are being used for bone or soft-tissue fixations per year and the need of such fixations devices in world orthopedic market is ever-growing. The cost effective bioresorbable composite device thus made is also having wider clinical applications with its higher bioactivity (biomineralization), biocompatibility, infection resistivity and proper bone remodeling properties.

Laijo Jose posted this:
Manager-Tech Transfer at Centre For Future (CFF)

This device is used for detection of most of the early cancerous and high-grade precancerous lesions of cervix and oral cavity. It gives a complete white light spectrum (equivalent to day light 5500-6000 K) and provides magnification with interchangeable lenses with optical power from 1 to 4 dioptre. The light of this instrument goes deeper inside the mucosal folds and provides a clear view with magnification for the differentiation of various categories of lesions. The aceto-white lesions of the cervix are screened by means of this device after the application of 5% freshly prepared acetic acid on cervix. The oral cavity is rinsed with 1% acetic acid solution for 20 seconds followed by water to remove the mucous and saliva and the examination is done. If any lesion suspicious for cancer is identified by this device, the observations regarding location, size, morphology and colour of the lesion are recorded and then confirmed cytologically and histologically. It is proved from the validation studies that this low cost portable device is with sufficient sensitivity and specificity in detecting high grade pre-cancerous and early cancerous lesions of uterine cervix and oral cavity. The technology provides a high sensitivity with a specificity of 94.3% for precancerous and early cancerous lesions of uterine cervix and reduces false positive results.

Yissum - Research Development Company of the Hebrew University posted this:

Self-assembly of fluorine-capped moieties for prevention of biofilms Keywords: self-assembly, dental, dentistry, biolfilm, disruption Project ID : 9-2015-3142
Anti-Infectious Coating for Dental Implants

Yissum - Research Development Company of the Hebrew University posted this:

Modeling structural drug descriptors for loading and leakage properties of liposomal drugs for the rational identification of new liposomal drug candidates. Project ID : 6-2016-4303

Yissum - Research Development Company of the Hebrew University posted this:

A New Tool to Diagnose and Monitor IBD Using Circadian Gene Expression Project ID : 8-2018-4562

Yissum - Research Development Company of the Hebrew University posted this:

New CNS-active carbamate derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide with a broad potent antiepileptic activity Project ID : 6-2017-4419
New CNS-Active Carbamate Derivatives for Epilepsy

Yissum - Research Development Company of the Hebrew University posted this:

Cluster9 Project ID : 6-2014-3054
Nano-Particles for Intranasal Delivery of Biodegradable Neuropeptide

Yissum - Research Development Company of the Hebrew University posted this:

Cluster9 Dispersible Concentrate Lipospheres for the Delivery of Agents (PNL) Project ID : 6-2017-4492
Oral Delivery Platform for Lipophilic Drugs Based on Pro-Nano Lipospheres