Industrial Biotechnology Technology Offers

Centre Technology Transfer CITTRU posted this:

Method for conjugation of biomolecules and its new use The subject of the offer is a novel method for conjugation of free thiol group(s) containing biomolecules comprising a biomolecule reaction with a gold-donor agent in which a -S-Au-S- bond is formed. Specifically, the method leads to a complex formation that is a protein cage. The new method comprises following steps: (i) biomolecules preparation, (ii) conjugation of biomolecules by reaction of biomolecules with gold-donor and (iii) purification of conjugation product.

Method for conjugation of biomolecules and its new use

Zymvol Biomodeling S.L posted this:

In silico enzyme engineering Zymvol is a service providing firm that assists companies in the discovery and development of new industrial enzymes through computer simulations.

Maria João Cardoso posted this:
Science and Technology Manager at UATEC - Unidade de Transferência de Tecnologia

Separation of nucleic acids using chromatographic matrices functionalized with ionic liquids Novel multimodal chromatographic supports prepared by functionalizing matrices with ionic liquids, allowing the separation of RNA and DNA in a single chromatographic step with high selectivity, robustness and reproducibility. In comparison to other commercially available supports, a higher dynamic binding capacity for RNA was obtained.

Separation of nucleic acids using chromatographic matrices functionalized with ionic liquids

Avazyme posted this:

Food safety, quality, authenticity and consulting services Avazyme offers agile and custom problem solving services to the food industry through the application of biological and chemical analytics. Differentiated from larger CROs that offer a rigid standardized menu of services, Avazyme is focused first on agile problem solving. Avazyme has state-of-the-art instrumentation and methodologies. Problem solving is applied to food safety, quality, authenticity and GMO testing. Avazyme also offers consulting in food regulatory science, Maximum Residue Levels (MRLs), import tolerances and food safety, quality and secondary standards, nutritional labeling, authenticity and GMO analysis. Consulting in new assay development, validation and certificate of analysis is also offered. Differentiated from larger CROs, Avazyme offers nimble, rapid and custom analytical method development and validation. Offers include development of laboratory and point of use assays. Avazyme offers organizations Independent Lab Validation (ILV). Avazyme is BSL2, EPA GLP, FDA GLP compliant and will work with companies requiring GMP and ISO17025 standards.

Food safety, quality, authenticity and consulting services

Maria João Cardoso posted this:
Science and Technology Manager at UATEC - Unidade de Transferência de Tecnologia

Magnetic nanoparticles for selective enrichment of proteins in complex mixtures New method for preparing ion chelating magnetic nanoparticles, which allow selective protein enrichment, namely metalloproteases (MMPs) and His-tagged proteins, from complex mixtures.

Magnetic nanoparticles for selective enrichment of proteins in complex mixtures

UNIVERSIDAD DE BURGOS posted this:

Anaerobic treatment of biodegradable waste liquids Bioreactor formed by two connected closed tanks (anaerobic digestion tank and filtration tank) for the anaerobic treatment of complex wastewater with biogas production. A support material is used, in a non-arranged way, increasing the active biomass accumulation capacity and allowing downwards flow in the digestion tank.

Anaerobic treatment of biodegradable waste liquids

NDI Foundation posted this:

Strain of bacteriorhodopsin-BR Bacteriorhodopsin (BR) is the newest biotechnological product that will make a revolution in many spheres of life: from medicine to defense. Data on the production of the BR in the world is hidden. From open sources - the only seller (and, possibly, producer) is an American company SIGMA, selling BR for research. We offer developed strain of BR. A method of producing allows to get BR in large quantities to several kg. The strain is certified and stored in special depositories. BR has unique qualities - the main one is - memory. For BR, it was necessary to find a special strain - producer of BR. Just several countries has the strain (USA, Russia, ..), other data hidden. We also developed such an unique strain.

Germans Trias i Pujol Health Sciences Research Institute posted this:

Biosignatures for ulcerative colitis Currently, the glucocorticoids are the first-line of treatment for of moderate-to-severe flare-ups. However, up to 40% of patients do not have an adequate response. Mechanisms of steroid-refractoriness in UC remains unknown. In addition, corticosteroid failure impair the effectiveness of rescue therapies.

TTPU posted this:

Anti-adhesive Biopolymer Coating Researchers have developed an anti-adhesive coating based on a polymer naturally and sustainable produced by a marine bacterium. This coating prevents the bacterial adhesion and the subsequent biofilm formation that usually leads to host bacterial infections difficult to eradicate and control with the antibiotics currently in use, namely in hospital environments. This coating can be applied in a cost effective way to a broad range of materials through the application of a universal glue.

University of Huelva posted this:

New procedure for the genetic transformation of plant cells and kit for carrying out said method The strategy for transformation is extremely simple and does not involves subcloning the gene of interest in any vector. The kit is not based on specific promoters or regulatory DNA sequences, thus it can be applied to many different plant species, from unicellular microalgae to higher plant protoplasts. Since the strategy is not based on specific promoter or regulatory DNA sequences, only the marker and the gene of interest sequences are inserted in the microalgal genome, avoiding the introduction of undeserible DNA sequences in the transformant strain. This is very important given the concern that transfer of exogenous DNA through transgenesis causes in the public opinion

New procedure for the genetic transformation of plant cells and kit for carrying out said method

Universidad de Alcalá-OTRI posted this:

Antimicrobial electrospun fiber membrane with retention and controlled release capacity of active substances Researchers from the Department of Analytical Chemistry, Physical Chemistry and Chemical Engineering of the University of Alcalá in collaboration with researchers from the Department of Chemistry and Physics of the University of Almería, presents a procedure for the manufacture of active membranes based on submicron fibers combining an antimicrobial action with the ability to retain apolar contaminants in aqueous solution. The membranes are produced by an electrospinning process in aqueous solution from mixtures of water soluble polyacids and polyols, which are subsequently stabilized by a thermal curing process and post-functionalized by the incorporation of amino-terminated dendrimers by a grafting process using a coupling agent. The material can be applied to the treatment of drinking water, to the regeneration of waste water, to the treatment of process waters and also to the controlled release of active substances, such as drugs, food preservatives, etc. The group seeks companies from the pharmaceutical, food, material technology and environmental sectors to sign technical cooperation agreements, commercial agreement with technical assistance and patent licensing agreements.

Antimicrobial electrospun fiber membrane with retention and controlled release capacity of active substances

Cracow University of Technology posted this:

Nano and microstructural fertilizing glasses Nanometals additive for fertilizing products affects the inhibition of growth of bacteria, fungi and viruses, which may attack the plants, especially in moist environment.

University of Vigo posted this:

Valorization of whey and vinasses by producing antimicrobial extracts using biotechnological processes This invention is based on the production of antimicrobial extracts with potential application against pathogenic microorganisms. The biotechnological production of antimicrobial metabolites was carried out using Lactobacillus plantarum strains. Two industrial wastes, whey, and wine distilled lees (or vinasses) were assayed in order to make the process economically competitive with regard to the chemical one. The extracts are mainly composed by lactic acid, 3-phenyllactic and bacteriocins. Whey was enzymatically hydrolyzed and the solutions were fermented sequentially or simultaneously. The bioprocesses were carried out continuously or discontinuously

Institute of Chemical Research of Catalonia posted this:

Crysforma: services in pharmaceutical solid state development Crysforma provides complete scientific support for the discovery, analysis and scale-up of polymorphs, hydrates, amorphous phases, salts and co-crystals of active pharmaceutical ingredients or intermediates. Crysforma has developed its own crystallization screening methodology based on the combination of several crystallization procedures. We use high-throughput crystallization systems controlled by highly skilled scientists to maximize the information drawn from each experiment. Our projects are always carried out in close collaboration with the client, adapted to the customer's needs and under strict confidentiality conditions.

Crysforma: services in pharmaceutical solid state development

UATEC - Unidade de Transferência de Tecnologia posted this:

Device for chromatic counting and quantification of organisms or particles in a suspension The execution of ecotoxicological tests with organisms in liquid medium, eg. Daphnia sp., requires its counting and characterization to evaluate several parameters. Currently the score is performed by technicians by direct observation (“naked eye”) of exposed organisms. This process is slow, tiring and subject to human error, and it can have adverse effects on visual acuity of the technical staff involved in the count. This patent, developed in a Portuguese university, solves the problem by counting and automating this process with gains in runtime and accuracy and enabling quick and efficient recount. It follows the optimization of the process of assessing the exposure to contaminants in tests that require the use of small-sized organizations. The university is looking for companies interested in the production and commercialization of this industrial equipment.

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