Technology Offers

Unitat de Valorització de la URV posted this:
Licensing Manager at Fundació URV

New composition for prevention, amelioration or treatment of obesity and metabolic syndrome-related diseases The invention consists in the design and evaluation of a functional ingredient composed of several bioactive compounds for the treatment of obesity and other metabolic syndrome-related diseases. Functionality of this multi-ingredient has been tested in a cafeteria diet-induced obesity model. It has been shown that animals fed a cafeteria diet develop metabolic syndrome. The chronic administration of our multi-ingredient product reduces the effect produced by the consumption of cafeteria diet. Hence, a reduction of body weight, improvement of insulin and leptin resistance and endothelial function, a hypolipidemic, hypoglicemic and antihypertensive effect have been observed. Nowadays, there are some functional ingredients to treat or prevent some aspects of these pathologies but the novelty of this invention is that the designed multi-ingredient product is able to act in several targets at the same time.

New composition for prevention, amelioration or treatment of obesity and metabolic syndrome-related diseases

CNIC (TTO) posted this:
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)

A new therapy for the treatment of myeloproliferative diseases Myelodysplastic/myeloproliferative neoplasms (MPN) are a group of diseases that affect normal blood cell production in the bone marrow. In this case the bone marrow causes an overproduction of one or more blood cell types (red cells, white cells or platelets). Complications arise over time due to the abnormally high number of blood cells that accumulate in the bone marrow and in the circulating blood. In many cases, these diseases develop slowly and get worse gradually. In some cases, MPN can progress to leukemia. Compounds capable of preventing and treating these types of diseases are urgently needed. CNIC researchers have identified new therapeutic targets based on alterations in the regulation of mesenchymal stem cells (MSC) in the hematopoietic niche by sympathetic nerves. They have also defined an in vitro method for prognosis/diagnosis of MPNs and/or to define the disease´s stage, and a method to screen for therapeutic compounds useful to treat MPNs.

A new therapy for the treatment of myeloproliferative diseases

CNIC (TTO) posted this:
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)

Use of selective Beta-3 adrenergic receptor agonists to treat pulmonary hypertension Pulmonary hypertension (PH), defined as the increase of mean pulmonary blood pressure above normal values, encompasses a series of disorders characterized by the increase of pulmonary vascular resistance and progressive deterioration of the right ventricle. The incidence of pulmonary hypertension in the population is high and it is associated with high morbidity and mortality. Approximately two thirds of patients with left ventricular dysfunction (systolic or isolated diastolic) develop pulmonary hypertension. Currently, there is a lack of treatments for pulmonary hypertension. CNIC and CLINIC researchers have described a novel effective treatment for pulmonary hypertension of different etiology, both chronic and acute. They have found that selective stimulation of beta-3 adrenergic receptors has a beneficial effect in pulmonary hypertension.

Use of selective Beta-3 adrenergic receptor agonists to treat pulmonary hypertension

CNIC (TTO) posted this:
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)

New microRNAs for the diagnosis of cardiomyopathies Inflammation in the myocardium or myocarditis is a disease with heterogeneous aetiology, frequently caused by an infectious pathogen, toxins, drugs or by an autoimmune disorder. Its clinical variability and its nonspecific symptoms make the diagnosis of myocarditis a process that is not always easy. There is an urgent need for accurate, fast point-of-care tests that simultaneously provide diagnostic and prognostic information about a patient entering the hospital with symptoms of acute heart failure. CNIC researchers have identified the role of an specific miRNA in cardiomyopathies processes and have studied the differential expression in blood plasma of patients compared with healthy subjects. These miRNAs can be used as biomarker to improve the diagnosis of acute myocarditis.

New microRNAs for the diagnosis of cardiomyopathies

CNIC (TTO) posted this:
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)

SHIP-1 inhibitors for prophylactic treatment and/or prevention of infectious diseases Trained immunity can be defined as a defacto innate immune memory that induces enhanced inflammatory and antimicrobial properties in innate immune cells. Innate immune cells can be trained to exhibit an enhanced and lasting response to subsequent infections with microbial components. Importantly, this boosted response can be triggered against pathogens diverse from those that induce the training. However, improving the heterologous response of trained innate immune cells remains complicated. CNIC, Syracuse University and SUNY Upstate Medical University researchers have discovered that the use of SHIP-1 inhibitors, enhance the non-specific response of trained innate immune cells. This increased activity may offer an improved prophylactic treatment or prevention of subsequent infections.

SHIP-1 inhibitors for prophylactic treatment and/or prevention of infectious diseases

Bara Prixova posted this:
Commercialization Specialist at Czech University of Life Sciences

Food Processor employing Pulsed Electric Field (PEF) Technology • Our device uses pulsed electric heating technology to process food at low temperatures (approx. 42⁰C). • High-voltage pulsation is a gentle way of preparing food, in which all healthy substances, especially vitamins, are preserved. • During processing, cell membranes in food cells are opened, which allows better absorption of vitamins and enzymes in the human body. • Food is sterilized by a pulsed electric field and is therefore suitable for direct consumption.

Unitat de Valorització de la URV posted this:
Licensing Manager at Fundació URV

New gas nanosensor that increases the sensitivity and durability of current sensors by 300%A new lead halide perovskite-graphene hybrid applied to gas sensing has been developed. Ultra-fast sensors able to work at room temperature have been developed and the role in the gas sensing mechanisms of different ions in perovskite nanocrystals decorating graphene elucidated. Our invention shows for first time that the anion and cation in the perovskite structure (ABX3) have a significant effect on gas sensing performance. In particular, gas sensors employing graphene decorated with different perovskite configurations were successfully employed to detect voc vapours at ppm levels.

New gas nanosensor that increases the sensitivity and durability of current sensors by 300%

Unitat de Valorització de la URV posted this:
Licensing Manager at Fundació URV

New Catalysts for olefin and polar monomer copolymerization and olefin polymerization The present invention deals with the development of new homogeneous catalytic systems for the synthesis of functionalized polyolefins featuring the polar vinyl monomer into the main polymer chain. Currently, the two technologies applied for the industrial production of functionalized polyolefins are: i. radical polymerization and ii. post-polymerization functionalization. Both technologies are based on radical processes that require high temperature (473 K) and pressure (3000 bar of ethylene), thus implying high energy consumption, low cost efficiency and poor control over the macromolecule structure. The new homogeneous catalytic system developed within this invention enables the production of functionalized polyolefins under very mild reaction conditions, temperature of 308 K and ethylene pressure of 2.5 bar, with a high control of the macromolecule architecture.

Jorian Bos posted this:
Other at EIT Digital

DC BRAIN - Optimise Your Networks in Real Time DCbrain is the Artificial Intelligence specialist applied to Energy and Logistics networks allowing industrial companies to optimize, forecast and make reliable flows to obtain operational recommendations in real time.

DC BRAIN - Optimise Your Networks in Real Time

Jorian Bos posted this:
Other at EIT Digital

CERBAIR - Drone detection and neutralisation via radio frequency CerbAir develops its Anti-Drone and Drone Detection Solutions from start to finish. Rethink your airspace security and trust us to defend your sensitive site or event from any kind of drone intrusion.

CERBAIR - Drone detection and neutralisation via radio frequency

Bara Prixova posted this:
Commercialization Specialist at Czech University of Life Sciences

Equipment for planting woody-seedlings in areas of precipitation deficiency TECHNOLOGY DESCRIPTION • The device applies a mixture of a hydrophilic polymer (hydrogel), water and optionally fertilizers and other substances at a specified dose to each seedling. • Hydrogels are strongly water-binding substances (up to 300 times their own weight), which can subsequently be used for growth and development. The water consumption of irrigated seedlings is reduced by half using hydrogel. Hydrogel also allows the growth of seedlings where it is due to lack of precipitation impossible (semi-desert, desert). Hydrogel is harmless, completely disintegrates after about five years (the time required for establishment of seedlings). • The device enables fast and efficient planting of eight thousand seedlings of forest trees, as well as agricultural crops such as coffee, banana and many others. • The device is ideal for use on large areas with low slope and well-paced terrain, such as plantations.

Equipment for planting woody-seedlings in areas of precipitation deficiency

Jorian Bos posted this:
Other at EIT Digital

FLYNEX - Data mining platform for industrial BI using automated drones The FlyNex system enables automated flight operations with fast compliance for flight certification, leading to unique data-generation for security, research, predictive maintenance, rehabilitation, and construction.

FLYNEX - Data mining platform for industrial BI using automated drones

Jorian Bos posted this:
Other at EIT Digital

VELCO - Urban Mobility made easy without reaching your phone Finally enjoy a simple and intuitive navigation system for your favorite means of transportation. Velco's offers a connected bike handlebar and flexible solutions for navigation and security services ideal for fleet managers and city mobility.

VELCO - Urban Mobility made easy without reaching your phone

Jorian Bos posted this:
Other at EIT Digital

MATCHX - End-to-end deep coverage network-solution MatchX develops superior LPWAN (Low-Power-Wide-Area-Network) hardware and software, a comprehensive IoT cloud and reporting solutions with blockchain. MatchX provides deep coverage reaching underground basements and inside refrigerators up to 20km+, ultra-low power (runs for 10+ years), a large connection number (connects over 60k sensors and devices with one MatchBox), and low cost.

MATCHX - End-to-end deep coverage network-solution

Jorian Bos posted this:
Other at EIT Digital

UNITED SIGNALS - Turning paper-based businesses into Streamlined Digital Dealmakers United Signals is a German specialist for paperless and easy to use client solutions. With products like digital onboarding, electronic contracts and client portals they support companies of all industries. Due to white label capabilities and the flexibility of the solution, the software can be used within short time to turn any forms or contracts into a digital version which can be signed contactless, even from home or mobile. It is multi-language and can easily be integrated into existing systems landscapes. United Signals and it's paperless onboarding solution was selected by the Association of Independent Asset Managers (VuV) and its members in Germany with the aim of becoming a market standard. Further it`s used by many leading banks in Germany including DAB BNP Paribas, V-Bank, comdirect, ebase, Baader Bank and Augsburger Aktienbank.

UNITED SIGNALS - Turning paper-based businesses into Streamlined Digital Dealmakers

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