Genetic Engineering / Molecular Biology Tech Calls | Innoget
Find Tech Calls and Research Funding in Genetic Engineering, Molecular Biology, Biochemistry, Microbiology, Biological sciences and Biophysics posted on Innoget
Find Tech Calls and Research Funding in Genetic Engineering, Molecular Biology, Biochemistry, Microbiology, Biological sciences and Biophysics posted on Innoget
Organization from European UnionOrganization from European Union posted this Technology Call
Seeking hyperbranched, non charged, short molecules/dendrimers able to be coupled to keratinous surfacesWe are seeking for molecules/compounds/materials which are chemically composed of two opposite parts (see Fig.). The first part of such molecules has a hyperbranched/dendrimer-like/fork shape. The second part (which is geometrically opposit to the first) is a moiety which will favour attachement. The attachment on the skin or hair surface could be generated by adhesion, covalent bonding, electrostatic attachment etc. For instance such latter moieity could react with free amines present on the hair fibers (more attachment points on the skin and hair could be considered, e.g. hydroxyl groups). Lactone groups are an example reported in literature of a reactive moiety which upon heat application can bound to the free amine of the hair. Once bounded to the skin/hair such molecules will work as molecular spacers. The molecules need to be neutrally charged, rigid, branched and have a low particle density (number of atoms in a physical volume). They will therefore decrease the interaction (e.g. Van der Walls attactions) between external particles (such as sand or dust) and the functionalized surface. Example: N-Glycans are an example of such molecular spacers and an example of desired geometrical structure. Glycan with 5 Mannose units for instance will occupy a Volume of 2.25 x 1.65 x 1.24nm with 162 atoms, which lead to a particle density of 35 x 10(^27) atoms/m^3. Such lower particle density will lead to a reduction of the Hamaker-interaction coeffiecint between the funcitonalized surface and an approaching particle. Such molecule will therefore lead to a decrease of the friction coefficient and adhesion forces.
Organization from SwitzerlandOrganization from Switzerland posted this Technology Call
Seeking compound libraries for a high throughput screening to develop new productsThe company is interested in library partners for rapid compound screening for it's new highly-flexible high throughput experimentation laboratory. This laboratory is designed with a plug-and-play concept, which allows quick integration of specialized workstations to automate each specific workflow. Now the company is looking for compound libraries as basis for a high throughput screening to develop new products for their businesses. For this purpose, they are seeking both synthetic and natural molecule collections and is open to partners from any country. While the company itself is interested to exploit the results of the screening a variety of cooperation is possible. Research cooperation agreements with research organizations might yield into publications or consequent R&D contracts. Technical cooperation with large libraries might help the libraries to describe their portfolio much more in detail or exclusively sell library components to the company. Depending on the development stage of the library compounds licensing compounds to the company might be an option. Depending on joint interests and capacities joint venture might be a way to further develop usability of compounds.
