Genetic Engineering / Molecular Biology Tech Calls | Innoget

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Organization from European Union posted this Technology Call

We are seeking for molecules/compounds/materials which are chemically composed of two opposite parts (see Fig.). The first part of such molecules has a hyperbranched/dendrimer-like/fork shape. The second part (which is geometrically opposit to the first) is a moiety which will favour attachement. The attachment on the skin or hair surface could be generated by adhesion, covalent bonding, electrostatic attachment etc. For instance such latter moieity could react with free amines present on the hair fibers (more attachment points on the skin and hair could be considered, e.g. hydroxyl groups). Lactone groups are an example reported in literature of a reactive moiety which upon heat application can bound to the free amine of the hair. Once bounded to the skin/hair such molecules will work as molecular spacers. The molecules need to be neutrally charged, rigid, branched and have a low particle density (number of atoms in a physical volume). They will therefore decrease the interaction (e.g. Van der Walls attactions) between external particles (such as sand or dust) and the functionalized surface. Example: N-Glycans are an example of such molecular spacers and an example of desired geometrical structure. Glycan with 5 Mannose units for instance will occupy a Volume of 2.25 x 1.65 x 1.24nm with 162 atoms, which lead to a particle density of 35 x 10(^27) atoms/m^3. Such lower particle density will lead to a reduction of the Hamaker-interaction coeffiecint between the funcitonalized surface and an approaching particle. Such molecule will therefore lead to a decrease of the friction coefficient and adhesion forces.
Seeking hyperbranched, non charged, short molecules/dendrimers able to be coupled to keratinous surfaces

Haier posted this Technology Call

Nowadays, consumers are more and more concerned about food safety and health. Food even stored properly may still grow bacteria with time goes on. So now we are seeking for technologies or solutions that can detect the total microbial counts in a closed space that can be integrated with refrigerator. The module shall be small in size and have a relatively long lifetime, as the lifetime of a refrigerator is 8-10 years. Currently, we do not set specific requirement for the detection accuracy. It would be accepted as long as it could detect and tell the total bacteria counts. Haier prefers to work with partners that have existing technologies or approaches that can be applied to this specific application. Collaboration can involve technology licensing, product sourcing, proof of concept leading to joint development agreements and assistance with scale-up to manufacturing. Preference will be given to technologies or approaches that currently have working prototypes that can undergo feasibility, validation or proof of concept over a 3-6 month period. Financial support for the proof of concept phase will be negotiated based on specific performance targets agreed between both parties. For selected collaborators Haier may provide access to samples, test equipment and testing facilities. Technologies will need to satisfy manufacturability, material cost and ease of use assessments to progress from the concept stage.
Seeking for bacteria detection method used in closed space