Consejo Superior de Investigaciones Científicas posted this:Transphagocytic T cells as anti cancer immunotherapyCSIC´s research group, in collaboration with scientists from the Centre of Molecular Biology “Severo Ochoa” (CBMSO-CSIC), the Autónoma University of Madrid and the Health Research Institute of the “La Princesa” University Hospital, developed a new method for anti-cancer immunotherapy based on transphagocytic lymphocytes (tiCD4+ T cells) Companies interested in a patent license or investors for creation of a start-up are being sought. An offer for Patent Licensing
Consejo Superior de Investigaciones Científicas posted this:Purine derivatives for the treatment of neurodegenerative diseasesCSIC has synthesized several substituted purine derivatives that are capable of inhibiting the activity of the CDC7 kinase. This inhibitory activity makes them useful for the treatment of neurological diseases. The compounds developed are, therefore, a new therapeutic alternative for Alzheimer's disease, amyotrophic lateral sclerosis or frontotemporal dementia. Industrial partners from pharmaceutical industry are being sought to develop and commercialized the compounds through a patent licence agreement. An offer for Patent Licensing
Consejo Superior de Investigaciones Científicas posted this:Kits for cell culture based on hydrogel coatingsCSIC and Complutense University of Madrid have developed new kits for cell culture based on cytocompatible hydrogels coated onto stiff substrates. Due to the excellent adhesion of the hydrogel to these substrates is possible to have mechanically robust platforms, easy to handle as required in a cellular biology laboratory. These new kits have been successfully tested showing an excellent cellular proliferation on the surface of the hydrogel. Besides, this technology allows the detachment of a cell monolayer without the need of chemical or biological agents preserving the viability of cell harvesting. Industrial partners from the biotechnology with expertise in cell culture are being sought to collaborate through a patent license agreement. An offer for Patent Licensing
Consejo Superior de Investigaciones Científicas posted this:Regulatory compounds of synaptic transmission for the treatment of neurological diseasesThe CSIC and IRYCIS (Ramón y Cajal Institute for Health Research) have developed a group of compounds. These compounds have the ability to regulate the number of synapses that are formed between neurons, as well as the probability that neurotransmitters are released from these, because they have the capability of modulate the interactions that take place between the regulatory proteins NCS-1 and Ric8a that regulate these two independent processes. Due to these neuromodulatory properties, these compounds are useful for the treatment of neurological diseases as Alzheimer's disease, Huntington or Parkinson's diseases among others. Industrial partners from the ophthalmic or pharmaceutical industry are being sought to collaborate through a patent license agreement. An offer for Patent Licensing
Centre Technology Transfer CITTRU posted this:Hospital emissions: N2O abatementThe subject of the offer is catalyst, α-Al2O3 supported, dedicated to reduce the emission of N2O in a low temperature range. Application: Hospital gases collectors, nitric acid production plant emitters, adipic acic production plant emitters.
Licensing Manager at uacoopera
uacoopera posted this:
Licensing Manager at uacoopera
Laser Consult Ltd. posted this:Thyroid Hormone Action Indicator Transgenic Mouse: the in vivo model to promote thyroid hormone-related R&DA Hungarian academic research institute developed a Thyroid Hormone Action Indicator (THAI) Mouse, a transgenic mouse model to measure the authentic thyroid hormone signalling in a live animal. They are looking for potential partners that would be interested in licensing the THAI mouse model. The target users are companies developing thyromimetics.
Laijo Jose posted this:
Manager-Tech Transfer at Centre For Future (CFF)
Universidad de Alcalá-OTRI posted this:Compounds for the treatment of Leishmania infectionsThe research group Heterobetainas of the University of Alcalá presents the preparation and uses of a series of compounds that act as bioactive agents against the Leishmania parasite and as therapeutic agents in the treatment of this disease, in both, its visceral (LV) version and in the mucocutaneous one (CML). The group is looking for pharmaceutical companies interested in manufacturing an active ingredient for the formulation of a leishmanicidal drug based on these compounds. The group proposes the signing of a patent license agreement, a collaboration agreement or a commercial agreement with technical
Universidad de Alcalá-OTRI posted this:Endothelial microvesicles with microbicidal effect for the preparation of a medicament or for a direct useThe research group "Cell damage associated with senescence" of the University of Alcalá presents the microbicidal capacity of endothelial microvesicles. These vesicles destroy the main pathogens involved in sepsis and even strains derived from them resistant to multiple antibiotics. They have also been shown to be effective against the biofilms that form these microorganisms. The group seeks to reach licensing agreements, cooperation or commercial agreements with technical assistance, with pharmaceutical companies interested in the design of new medicines.
Universidad de Alcalá-OTRI posted this:Development and method of construction of a new electrochemical sensor of Magnesium (Mg2 +), without the need to add organic salts, additives or organic solvents to the sampleThe research group in Bioelectrochemistry and Biosensors of the University of Alcalá in collaboration with the Textile Industry Research Association (AITEX) has developed an electrochemical sensor of magnesium (Mg2 +) and a construction method based on the formation of a polymeric three-dimensional network that allows the entrapment / immobilization of a selective indicator for Mg2 +, eriochrome black T, by the use of a crosslinking agent and a polymer. The combination of these three reagents allows the construction of the sensor on any conductive surface, avoiding the electro polymerization of the indicator. The resulting sensor allows to measure MG2 + in any type of samples, without the need to add organic salts, additives or organic solvents. The quantification of Mg2 + is done directly by incubating the sensor in the sample containing the analyte, resulting in a modification of the amperometric signal proportional to its concentration. This method has many applications especially in health and biomedical sector since Mg2 + participates in such important activities as neuronal, neuromuscular transmission, or regulation of blood pressure and plays a key role in various pathologies such as vascular and migraines headache. The group is looking for companies in the agro-food, bio-sanitary and environmental sectors, with the aim of reaching technical collaboration agreements, commercial agreements or patent licenses.
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Germans Trias i Pujol Health Sciences Research Institute posted this:Apotransferrin to treat strokeOur group has demonstrated that intravenous administration of apotransferrin strongly reduces the brain damage (up to 75%) in 3 different rat models including both transient and permanent ischemic stroke and improves the neurological impairment (neuroscore 60%) induced by stroke. Thus, this new approach may benefit not only stroke patients who can be treated with current treatment to induce recanalization (transient stroke) but also the 80% of patients who could not benefit from current therapies directed to induce recanalization of the artery (permanent strokes). Results in the preclinical area and some results obtained in serum of stroke patients lead us to think that apotransferrin is a good neuroprotector in the early stages of the ischemic event.
University of Vigo posted this:Method for the sequential immunochemical evaluation on a same biological sample of NCAM (Neural Cell Adhesion Molecule) protein and its PolySialic Acid (PSA) tail, by western blot coupled to chemiluminiscence detection.The method optimizes the expression assays of PSA-NCAM isoforms in biological samples available in small quantities or restricted (as is the case of human specimens, for example). It improves quantitative and qualitative performance of PSA-NCAM analysis by western blot.
JPT Peptide Technologies posted this:Custom Peptide SynthesisJPT Peptide Technologies has a substantial, long-standing expertise in custom peptide synthesis services, providing custom peptides with highest quality for even complex or unusual peptide sequences. If you would like to order a quality peptide synthesis service using regulated processes, choose JPT! Furthermore, our peptide synthesis service has a very high success rate (over 99%) as JPT has developed the know-how to choose and optimize the appropriate synthesis method for each peptide. We go the extra mile to get your peptides done!