Centre Technology Transfer CITTRU posted this:In vivo delivery system of the DNA modifying enzymesThe subject of the offer is a new method of in vivo genome editing with the use of hybrid nucleases, such as ZFN, TALEN and the CRISPR/Cas9 system, delivered to target cells by EVs derived from stem cells in serum-free conditions and defined as the RNA-containing vesicles expressing stem cells surface markers: CD90, CD105, CD147, CD309 (in more than 20% of RNA-positive events) and lack of expression CD45.
Yissum - Research Development Company of the Hebrew University posted this:A New Tool to Diagnose and Monitor IBD Using Circadian Gene ExpressionA New Tool to Diagnose and Monitor IBD Using Circadian Gene Expression Project ID : 8-2018-4562
Maria João Cardoso posted this:
Science and Technology Manager at UATEC - Unidade de Transferência de Tecnologia
Lucas Montes posted this:
Technology Transfer Advisor at University of Granada (OTRI)
Yissum - Research Development Company of the Hebrew University posted this:OnTimeBio LTDOnTimeBio is developing a highly sensitive blood test to enable timely detection and monitoring of diseases. OnTimeBio's product utilizes advanced computational approaches with genomic and epigenomic approaches in order to enable a quantitative and exact readout of tissue dynamics across the organs of the human body. Applying the technology across multiple diseases, including cancer, metabolic, autoimmune, and neurodegenerative diseases, can reduce patient suffering and enable better treatment outcomes while lowering healthcare costs. For developers of novel therapeutics, the technology provides a lens to the body's response across all targeted tissues. This allows better patient stratification and precise and swift monitoring of patients' responses to new therapies. Project ID : 26-2017-4403
Universidad de Alcalá-OTRI posted this:Synthesis of dendritic systems of nanoscopic size for applications in biomedicineRegarding the cationic systems developed, the principal innovative aspects are the following: - They are non viral nanoscopic synthetic molecules able to internalise nuclear material inside different cellular lines. This turns them into good candidates to be considered as non viral vectors in gene therapy processes. - They are non toxic in a concentration range adapted for the accomplishment of different biomedical studies. - They present antibacterial properties against gram + and gram- bacteria - They are able of interacting, in a electrostatic way, with anionic drugs which turns them into drug delivery systems. - They present a hydrophobic carbosilane skeleton that allows the molecules to cross the cellular membranes with major facility. - They are soluble in water. Regarding the anionic systems developed, the principal innovative aspects are the following: - They have an important antiviral capacity - They are able to inhibit the infection for HIV - They have antiinflammatory capacity - They are good candidates for the production of a microbicide gel of topic use that prevents the infection of the virus across sexual transmission.
Small and Medium Enterprise
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