Diagnostics, Diagnosis Technology Offers

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Laijo Jose posted this:
Manager-Tech Transfer at Centre For Future (CFF)

This device is used for detection of most of the early cancerous and high-grade precancerous lesions of cervix and oral cavity. It gives a complete white light spectrum (equivalent to day light 5500-6000 K) and provides magnification with interchangeable lenses with optical power from 1 to 4 dioptre. The light of this instrument goes deeper inside the mucosal folds and provides a clear view with magnification for the differentiation of various categories of lesions. The aceto-white lesions of the cervix are screened by means of this device after the application of 5% freshly prepared acetic acid on cervix. The oral cavity is rinsed with 1% acetic acid solution for 20 seconds followed by water to remove the mucous and saliva and the examination is done. If any lesion suspicious for cancer is identified by this device, the observations regarding location, size, morphology and colour of the lesion are recorded and then confirmed cytologically and histologically. It is proved from the validation studies that this low cost portable device is with sufficient sensitivity and specificity in detecting high grade pre-cancerous and early cancerous lesions of uterine cervix and oral cavity. The technology provides a high sensitivity with a specificity of 94.3% for precancerous and early cancerous lesions of uterine cervix and reduces false positive results.

Unitat de Valorització de la URV posted this:
Licensing Manager at Fundació URV

Cystic Echinococcosis, also known as hydatid disease (Hydatidosis), is a parasitic disease caused by the tapeworms of genus Echinococcus. Hydatidosis is globally distributed and found in every continent except Antarctica. Endemic areas are parts of Argentina, Peru, East Africa, Central Asia and China. The infection to humans occur through the ingestion of parasite eggs in contaminated water, food, soil or through direct contact with animal hosts such as dogs and sheep. Human infection with E. granulosus leads to the development of one or more hydatid cysts located most often in the liver and lungs, and less frequently in the bones, kidneys, spleen, muscles, central nervous system and eyes. The asymptomatic incubation period of the disease can last many years until hydatid cysts grow to an extent that triggers clinical signs. The diagnosis is done through ultrasonography imaging, which is usually complemented or validated by computed tomography and/or magnetic resonance imaging scans. Cysts can be incidentally discovered by radiography. Specific antibodies are detected by different serological tests and can support the diagnosis. Biopsies and ultrasound-guided punctures may also be performed for differential diagnosis of cysts from tumours and abscesses. In this invention, a new system for non-invasive, early, fast and easy to use diagnosis test for Hydatidosis from exhaled breath analysis has been developed.
New method for the diagnosis of diseases caused by helminths

Maria João Cardoso posted this:
Science and Technology Manager at UATEC - Unidade de Transferência de Tecnologia

New method for preparing ion chelating magnetic nanoparticles, which allow selective protein enrichment, namely metalloproteases (MMPs) and His-tagged proteins, from complex mixtures.
Magnetic nanoparticles for selective enrichment of proteins in complex mixtures

Universidad de Alcalá-OTRI posted this:

The research group in Bioelectrochemistry and Biosensors of the University of Alcalá in collaboration with the Textile Industry Research Association (AITEX) has developed an electrochemical sensor of magnesium (Mg2 +) and a construction method based on the formation of a polymeric three-dimensional network that allows the entrapment / immobilization of a selective indicator for Mg2 +, eriochrome black T, by the use of a crosslinking agent and a polymer. The combination of these three reagents allows the construction of the sensor on any conductive surface, avoiding the electro polymerization of the indicator. The resulting sensor allows to measure MG2 + in any type of samples, without the need to add organic salts, additives or organic solvents. The quantification of Mg2 + is done directly by incubating the sensor in the sample containing the analyte, resulting in a modification of the amperometric signal proportional to its concentration. This method has many applications especially in health and biomedical sector since Mg2 + participates in such important activities as neuronal, neuromuscular transmission, or regulation of blood pressure and plays a key role in various pathologies such as vascular and migraines headache. The group is looking for companies in the agro-food, bio-sanitary and environmental sectors, with the aim of reaching technical collaboration agreements, commercial agreements or patent licenses.
Development and method of construction of a new electrochemical sensor of Magnesium (Mg2 +), without the need to add organic salts, additives or organic solvents to the sample

RAMOT at Tel Aviv University Ltd. posted this:

Surface Plasmon Amplification of stimulated emission Project ID : 11-2011-127