Technology Transfer OfficeView Profile
Center for Technology Transfer and Commercialization of Novosibirsk State University posted this:Preparation of Microscope Slides for medical, biological and veterinary purposesIn a laboratory of Virology and Morphology of an Academic University (Novosibirsk, Russia) the technology of production of high-quality microscope slides for histologic researches was developed. The technology can be applied in educational purposes as well as in different research programs in Pharmacology, Medicine, Biology, etc. The authors are looking for potential partners in order to hand over the technology and/or establish joint production and market implementation of biological exemplars.
Universidad de Alcalá-OTRI posted this:Development and method of construction of a new electrochemical sensor of Magnesium (Mg2 +), without the need to add organic salts, additives or organic solvents to the sampleThe research group in Bioelectrochemistry and Biosensors of the University of Alcalá in collaboration with the Textile Industry Research Association (AITEX) has developed an electrochemical sensor of magnesium (Mg2 +) and a construction method based on the formation of a polymeric three-dimensional network that allows the entrapment / immobilization of a selective indicator for Mg2 +, eriochrome black T, by the use of a crosslinking agent and a polymer. The combination of these three reagents allows the construction of the sensor on any conductive surface, avoiding the electro polymerization of the indicator. The resulting sensor allows to measure MG2 + in any type of samples, without the need to add organic salts, additives or organic solvents. The quantification of Mg2 + is done directly by incubating the sensor in the sample containing the analyte, resulting in a modification of the amperometric signal proportional to its concentration. This method has many applications especially in health and biomedical sector since Mg2 + participates in such important activities as neuronal, neuromuscular transmission, or regulation of blood pressure and plays a key role in various pathologies such as vascular and migraines headache. The group is looking for companies in the agro-food, bio-sanitary and environmental sectors, with the aim of reaching technical collaboration agreements, commercial agreements or patent licenses.
Universidad de Alcalá-OTRI posted this:Method of diagnosis of non-invasive renal failure and prior to symptoms and functional disordersThe Renal Nephropathy research group at the University of Alcalá presents a method of diagnosis of Renal Insufficiency (RI), in all varieties of the disease, that determines the amount of protein related to parathyroid hormone (PTHrP) present in a sample of urine, comparing said amount with at least one reference value and diagnosing RI from said comparison. The research group seeks companies from the diagnostic medicine, biomedicine or pharmacy sector to establish licensing agreements, collaboration agreements or commercial agreements with technical assistance.
Research InstituteView Profile
Germans Trias i Pujol Health Sciences Research Institute posted this:Diagnostic biomarkers for dementia with Lewy BodiesThe present data provide a solid basis for the development of genetic biomarkers for the early identification of patients suffering from dementia with Lewy bodies and to classify them into specific molecular subtypes. One of the biomarkers correlates with the development of Lewy pathology in the brain and may be useful to monitor the success of possible alpha-synuclein antiaggregatory therapies.
Technology Transfer Office
University of Granada (OTRI) posted this:Dual Probes for Flow Cytometry and Mass CytometryResearchers of the University of Granada have developed probes based on nanoparticles, both fluorescent and functionalized with metals, which act as dual probes, and can be used for both flow cytometry (FACS –Fluorescent-Activated Cell Sorting) and mass cytometry (CyTOF -Cytometry by Time-Of-Flight-). The probes can be used for bar coding of living cells or carrying out in vivo studies of different cell lineages through cell co-cultures as well as the activation of drug precursors through cytoplasmic catalysis of organometallic reactions inside living cells.
RAMOT at Tel Aviv University Ltd. posted this:Surface Plasmon Amplification of stimulated emissionSurface Plasmon Amplification of stimulated emission Project ID : 11-2011-127
RAMOT at Tel Aviv University Ltd. posted this:Low energy laser bio-stimulation of bone marrow stem cells for the treatment of myocardial infarctionHeart diseases are the leading cause of death worldwide. Low energy laser (light) irradiation has been shown to have bio-stimulatory beneficial effects on various biological processes in vitro, in vivo and also in clinical trails. We have explored the beneficial effects of light therapy (LT) on stem cells in the bone marrow in order to determine its potential application as cell therapy for the heart post myocardial infarction (MI). Preliminary results have shown that in the infarcted rat heart model the application of LT to the rat bone marrow (BM) in the hind leg 10 min and 4 hrs post MI caused a significant reduction of 79% and 75 % respectively in the scar tissue formed after MI. This is a novel, simple and non-invasive approach to improving heart function after heart attack in patients, and may also serve as a basis for cell therapy of other diseased organs. The fact that LT demonstrated efficacy in scar reduction 4 hours post MI, indicates its clinical relevance to treat patients post MI. Project ID : 2-2011-143
Research & Technology Organization
UNIVERSIDAD DE ALICANTE posted this:A decision support system for melanoma diagnosis.A Spanish Research Group has developed a system to help in the recognition of a melanoma through the visual characteristics of an image of the skin lesion. This system can be used as an automated way to decide the urgency to refer a patient to the dermatologist.
Fundació URV posted this:A robust breast cancer computer-aided diagnosis systemWe analyze breast cancer in mammographies, ultrasonographies, magnetic resonance imaging (MRI) and thermographies. Our analysis includes mass/normal breast tissue classification, benign/malignant tumor classification in mammograms and ultrasound images, tumor detection in thermograms, mammogram registration and analysis of the evolution of breast tumors. We also quantify and visualize the evolution of breast tumors in patients undergoing medical treatment. While the previous works mainly focus on analyzing one type of breast images, we implement a robust CAD system for detecting, classifying and studying the evolution of breast cancer. This CAD system analyzes breast cancer in several types of medical images. To implement our CAD system, we use computer vision, pattern recognition and machine learning methods. We also need to collect a large scale breast cancer dataset from hospitals. This dataset should include mammograms, ultrasound, thermograms and MRI images for the same patients. Our CAD gives accurate diagnosis results because it gathers information from different sources.
UATEC - Unidade de Transferência de Tecnologia posted this:System for the collection , storage and exhaled alveolar air conditioning for clinical analysisA group of researchers from Portuguese university developed a device that allows the collection and storage of the exhaled alveolar air by humans. The invention aims simultaneously to overcome some of the technical difficulties in the current state of the art, such as i) little or no response in the selective collection of alveolar air fraction ii) the inability to couple systems that allow concentration/extraction of analytes of interest iii) the inexistence of systems to the storage of the collected biofluid under controlled conditions and iv) the inability to collect exhaled air in liquid or vapor state. The university is looking for companies interested in the industrial production of the equipment and its commercialization.
Fundació URV posted this:Potentiometric sensor for the quantitative determination of creatininePotentiometric sensor for the quantitative determination of creatinine in biological fluids and other aqueous media. By a new ionophore incorporated into a polymeric membrane that allows screening creatinine real samples. The use of said ionophore in the polymer membrane solve the selectivity problem found in other methods.
Institute of Chemical Research of Catalonia posted this:Optical Quantification of enzymatic activity: a non-invasive diagnosis toolThe platform allows for accurate measurement of the enzymatic activity thanks to the presence of an optical signal that remains unchanged during digestion and serves as a ruler to which modifications of another signal, affected by enzymatic activity, is compared. The platform can be used in small devices, at point of care and in non-invasive diagnostic procedures. The platform is also highly versatile as a simple modification of the particle will allow using it in totally different diagnostic applications.