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 | Seeking tech innovations that can slow and track the spread of emerging disease outbreaks |
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How can communities around the world prepare for, detect, and respond to emerging pandemics and health security threats? Coronavirus disease 2019 (COVID-19) is the latest in a series of infectious disease emergencies, including cholera, Ebola, SARS, Chikungunya, HIV/AIDS, and influenza. While scientists and drug developers, with support from governments and multilateral organizations, have been rushing to produce, test, and deliver vaccines and treatments, tech innovators also have a crucial role to play, both in the near term and to prevent and mitigate future disease outbreaks. In the near term, we need improved solutions for prevention, accurate detection, and rapid response. MIT Solve is seeking tech innovations that can slow and track the spread of an emerging outbreak, for example by improving individual hygiene, developing low-cost rapid diagnostics, analyzing data that informs decision making, and providing tools that support and protect health workers. At the same time, we cannot solely treat disease outbreaks reactively. Climate change and globalization leave us ever more vulnerable to future epidemics and pandemics, and it’s critical to be prepared. Solve is also seeking solutions that focus on preventative and mitigation measures that strengthen access to affordable primary healthcare systems, enhance disease surveillance systems, and improve healthcare supply chains. |
 | Seeking products and technologies that contain a fast-moving, consumable product to treat, prevent and/or otherwise improve the symptoms of common skin conditions, including, but not limited to: acne, dermatitis, eczema, psoriasis, rosacea, sensitive |
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Healthy, clear skin is a key component to overall health, and can affect one's mental, emotional and physical well-being. When we're comfortable in our own skin, it boosts our self-esteem and confidence. For those that suffer from chronic skin conditions, the journey to clear skin can be long, difficult and expensive. People are often faced with the dilemma of choosing between products that are safe, but don't work well or dealing with the side effects of prescription medications and harsh chemicals. Looking to help consumers with chronic skin conditions live comfortably and confidently in their own skin. |
| | Seeking products, technologies and packaging that will improve the benefit areas of: Manage and/or enhance Digestive Wellness |
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We are interested in products, technologies and packaging that will improve the benefit areas of: Manage and/or enhance Digestive Wellness. |
 | Device for passive supression of vortex-induced vibrations (VIV) in structures |
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The present invention relates to a device for suppression of Vortex-induced vibrations (known as VIV) in flexible structures or in elastically supported rigid structures. Vortex-induced vibrations are a type of fluid-structure interactions that are consequence of the unsteady periodic forces generated in the wake of bluff bodies when affected by currents. The forces induced on the structures as a result of the large region of separated flow in the wake of the structure, result in vibrations. Vibrations can be fatal in engineering applications. Structures with low mass and damping are the ones in which VIV can be more important. In marine applications, most of the structures are characterised by combined low mass-damping. Although VIV is crucial in marine applications, the invention described here could also be used to prevent VIV in other non-marine scenarios such as structures affected by winds. |
 | Improving stem cell culture using carnivorous plants |
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Mesenchymal Stem Cells (MSCs) are multipotent precursor cells with the unique capacity to self-renew, proliferation and transformation into specialized cells present in many body tissues, such as muscle, adipose tissue, fibroblasts, cartilage, tendons, and nervous tissue. They are also characterized by the ability to affect the immune system by secretion of compounds that support the immune response directed among others against bacteria and parasites. They have properties enabling the secretion of chemical compounds that stimulate the formation of new blood vessels. All these attributes make them applicable in regenerative medicine, transplantology and in the treatment of many diseases. The umbilical cord blood and Wharton’s jelly MSCs are the sources from which MSCs are obtained. Due to the small amount of MSCs in the starting material, it is necessary to lead in vitro cultures to obtain sufficient numbers of cells that can be administered to the patient. Methods of isolation and culture of mesenchymal stem cells, including the growth medium, play a crucial role in obtaining the appropriate biological material that guarantees therapeutic success. Therefore, continuous improvement of procedures for isolating and in vitro culturing of MSCs is extremely important. The subject of the offer is a method of culturing mesenchymal stem cells using secretions from carnivorous plants, which increase cell adherence and proliferation, counteract their transformation into specialized cells, therefore, they longer maintain their pluripotency. |
 | Production of chymosins from camel and bovine origin using recombinant yeast strains |
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The use of chymosins for the production of cheese and cheese derivatives from milk has been known for years, and nowadays this technique has completely substituted the use of calf rennet. Biochemize SL has developed several recombinant yeast and bacteria strains able to express chymosins from bovine (chymosin A and chymosin B) and from camel origin, with very good expression levels (between 0,1 and 3 g/L) and activity. |
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