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 | Seeking Moisture Barrier for Flexible Packaging |
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PepsiCo is looking for novel resins that can co-extrude with their core resins to form a skin layer with high functionality that can anchor metal to film or highly functional coatings which would serve the same purpose. Inherently high barrier coatings that can be applied as primer coating or top coating over metal could also be a solution. |
 | Testing of drugs against SARS-CoV-2 |
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ViroStatics will determine cytotoxicity of test compounds/medicines in appropriate cell lines and will evaluate compounds/medicines provided by the Client for activity against new coronavirus |
 | Stable inhibitors of the 5-lipoxygenase pathway for treating Asthma and Cancer |
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The University of Leipzig has patented a series of Carborane-Based Inhibitors of the 5-LO Lypoxygenase pathway. These inhibitors are selectively cytotoxic towards several leukotriene-dependend melanoma and colon cancer cell lines., while leaving non-malignent cells intact. Furthermore, these inhibitor analogues have shown co-inhibition of heat shock proteins necessary for tumor development in such cell lines. Experimental results on mice showed promising results. Moreover, since these compounds have a high content of boron, they may also be suitable for Boron Neutron Capture Therapy (BNCT), a binary cancer therapy that uses selective boron compounds and thermal neutrons. Furthermore, leukotriene inhibition could be useful in the treatment of asthma, as their production is related to inflammatory responses. The BBZ is looking for organzations interested in acquiring this technology offer, helping perform precilinical and clinical studies, and ultimately leading to the licensing of it. |
 | Alternative source of fresh drinking water for Beverage Bottling Plants |
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The water quality in specialty beverages plays a huge role in the finished product. Without a proper filtration process, you could be letting unwanted minerals and bacteria alter the taste and look of your drink. |
 | Smart Self-Centered Shear Wall (SSCSW) System |
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Improves recovery of structures after removing the loads compared to current steel plate shear wall (SPSW). Potentially improves the lifespan of a building under various loading conditions, particularly earthquakes. |
 | Duty-Cycle Controlled Switched-Capacitor Buck Voltage Regulator for Efficient On-Chip Power Management |
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This technology relates to a voltage regulator architecture that generates a regulated output from an input voltage using a switched-capacitor circuit that periodically produces multiple intermediate voltage levels, followed by a low-pass filter to provide the regulated output. The approach uses phase interleaving to increase effective switching frequency and reduce switching losses. Regulation is achieved by modulating switch resistance via duty cycle control, which in turn controls the average voltage on flying capacitors. A control unit selects the operating region and drives switch configurations via a state-machine-based controller. |
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