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Seeking Solutions for Enhanced Delivery of Oral Care Actives and Flavors

• Posted by The Procter & Gamble Company
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• Project Size : 250,000 - 1,000,000 €

To improve the performance and consumer experience of oral care products using formulation excipients to improve deposition, retention and protection of actives, flavors, and sensates for extended periods

Seeking Respiratory Solutions and Technologies

• Posted by The Procter & Gamble Company
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• Project Size : 250,000 - 1,000,000 €

Our preference is to find opportunities that are on-market, market-ready, or require limited development. Opportunities may consist of new product forms, packaging innovations, delivery technologies, or new products.

Seeking Biomanufacturing of Transformational Ingredients in Consumer-Packaged Goods

• Posted by The Procter & Gamble Company
• ·
• Project Size : 250,000 - 1,000,000 €

We are looking for approaches to engineer and optimize organisms (microbial and plant) for production and/or purification of relevant biomolecules in a non-trial-and-error format. It is believed that starting from a waste stream will be a more cost-effective solution. We are also interested in plant- or algae-based solutions that are scalable and cost effective. What We Are Looking For: • Strain engineering approaches that achieve target molecule production targets across multiple molecule classes in significantly less time versus the industry average • Host engineering capabilities in non-model systems • Scale up platforms/methods that are amenable to commodity scale ingredients • Downstream processing methods/technologies that facilitate continuous extraction and/or re-use of extractive reagents • Approaches that leverage feedstocks separate from the food chain

Precursors of linear polyacenes: entry door to new semi-conductor materials

• Posted by Institut Català d'Investigació Química (ICIQ)
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• Patents for licensing

A new strategy for the preparation of precursors of linear acenes has been developed. The developed acene precursors are hydrogenated acenes and are stable upon storage. They can be prepared in several synthetic steps using two catalytic key preparation steps. The precursors can be deposited onto surfaces and submitted to annealing to generate the linear acene. This strategy afforded the first-ever preparation of undecacene.

Industrial production of humic and fulvic acid from biomethan digestate

• Posted by Fabian Belin from Luxembourg Institute of Science and Technology (LIST)
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• Innovative Products and Technologies

Anaerobic digestion is a process able to degrade organic waste to methane using a diverse microbial community. However, not all organics present in the feedstock can be biologically degraded and the undegraded fraction are disposed to fields or incinerated. This fraction, called the digestate, is underexploited and represents an interesting source of humic substances as they remain undegraded during the AD process. Our solution consists of a series of process to extract and concentrate those humic substances, specially fulvic acid. The first step is the mechanical separation of the liquid and solid phases. Then the liquid fraction undergoes a serie of filtration to remove inorganic precipitates, large particules and impurities. Then the concentration is done by reverse osmosis where the water is removed, and the humic substance solution retained. This technology allows a recovery of 60% of the humic substances in a solution containing at least 50% of fulvic acids. Further concentration steps can be done if necessary to obtain a solution with a minimum concentration of 12% w/w.

Liquid biopsy for early detection of cancer or precision medicine

• Posted by CNIC (TTO) from Spanish National Center for Cardiovascular Research (CNIC)
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• Patents for licensing

Scientists at EMBL-EBI, CNIC and CSIC have discovered a new type of telomere fusion that is not present in blood from healthy donors but can be detected well in the blood of cancer patients. They developed computational tools for the reliable identification of these fusions. Additionally, predictive models have been established that allow for the detection of the presence of a tumour using sequencing data from a blood sample. We hereby present an approach for a highly specific, minimally invasive and early detection of cancer. The sensitivity and false positive rate are comparable to recent liquid biopsy analysis methods. The performance of the tools is comparable across cancer stages. The tool has been validated using close to 10,000 whole genome sequencing datasets.