Pharmaceutical Products / Drugs Technology Offers

Universidad de Granada posted this:

Compounds for the treatment of Leishmaniasis and other diseases caused by trypanosomes.Several compounds have been synthesized that are useful for the treatment of Leishmaniasis and other diseases caused by parasites of the Trypanosomatidae family. These compounds show an improvement in the antiparasitic activity and reduced toxicity compared to the usual commercial treatments, causing damage to the key enzyme in the survival of the parasite without significantly affecting that of the human host. Therefore, they are a potential alternative to current treatments used to fight against Leishmaniasis or Chagas disease.

Fabiola Moreno posted this:
Technology Licensing Assistant at Binghamton University

Treatment of L-DOPA-induced Dyskinesia in Parkinson’s Disease Repurposed antidepressant agents for treating levodopa-induced dyskinesia (LID) in Parkinson's disease dramatically reduced LID and maintained these effects for several weeks without altering L-DOPA’s positive anti-parkinsonian effects.

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

Cathepsin K Targeted Library for offer We offer the Cathepsin K Targeted Library. It contains 761 compounds with predicted inhibitory activity against this protease and suitable for the early stage of drug discovery

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

Catechol O‑Methyl Transferase Targeted Library OTAVAchemicals offers Catechol O‑Methyl Transferase (COMT) Targeted Library. It contains 504 compounds with predicted inhibitory activity against this enzyme. The library has been carefully designed with combination of ligand- and receptor-based pharmacophore modeling.

Covid-19 Innovation Challenges by Innoget posted this:

Viral RNA-dependent RNA Polymerases Viral RNA-dependent RNA Polymerases (RdRPs) Targeted Library (1259 compounds) with predicted activity against viral RdRPs is offered. It has been carefully designed using machine learning (artificial neural networks and Bayesian statistics

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

Viral RNA-dependent RNA Polymerases Viral RNA-dependent RNA Polymerases (RdRPs) Targeted Library (1259 compounds) with predicted activity against viral RdRPs is offered. It has been carefully designed using machine learning (artificial neural networks and Bayesian statistics

LUCIA CORAL posted this:
Knowledge Tranfer Manager at National Cancer Institute CRO Aviano

Cell models to evaluate activity of p53:MDM2 inhibitors Twist GAIN-of-function and LOSS-of-function cell models were developed and used for preclinical p53:MDM2 inhibitors evaluation, preliminary demonstrating that the expression of Twist hampers their efficacy. These findings support patient stratification on the basis of twist expression for treatment of a large fraction of sarcomas but also of a fraction of carcinomas. (Piccinin et al., Cancer Cell, 22, 404-415, Sept 11 2012).

Centre Technology Transfer CITTRU posted this:

Mouse model of primary biliary cholangitis and Method for selection of active compounds for treatment and/or prevention of primary biliary cholangitis The subject of the offer is mouse model of primary biliary cholangitis and method for selection of active compounds for treatment and/or prevention of primary biliary cholangitis.

Covid-19 Innovation Challenges by Innoget posted this:

Systematic Computational Drug Repositioning to Treat COVID-19 Systematic Computational Drug Repositioning to Treat COVID-19 The genetic revolution which has taken place in recent years brings new opportunities to the field of drug discovery & repositioning. Using advanced comparative genomic, and data integration, our lab has been developing a state-of-the-art AI algorithm which maps drug and food supplements that are useful in treating diseases and improving health conditions. To create this algorithm, we have been integrating and analyzing massive amounts of genomic data from 1,600 genomes, 14 thousand compounds, 20,000 human genes, and a comprehensive database of phenotypic data. Project ID : 47-2020-10880

Yissum - Research Development Company of the Hebrew University posted this:

High Throughput Screening of Antimicrobial Agents Using Microfluidics Yonatan is a Phytopathology expert using microfluidics system to do high throughput screening of libraries to identify antimicrobial agents which can be either chemical or biological (proteins or bacteria). Yonatan is testing pathogens sensitivity against combinations of bacteria and chemical agents from the libraries using the high-throughput microfluidics system. When Potential Producer, Potential Inducer have a combined affect on a Pathogen target (killing) efficiency become of interest. This is because in nature a single bacteria species is susceptible to environmental stresses but when combined with helper bacteria they support each other synergistically. Project ID : 47-2019-10825

Yissum - Research Development Company of the Hebrew University posted this:

Repurposed Drugs for COVID-19 Treatment CHLOROQUINE AND HYDROXYCHLOROQUINE LIPOSOMES FOR INHALATION Aims to inhibit intracellular processing of the virus that has reached cells in the lung, using a different formulation and active ingredient with completely different modes of action than Project 1. A well-established and clinically used active pharmaceutical ingredient targeting infected lungs is being repurposed and a trial formulation is ready for lab models 1 out of 3 technologies of Chezy of liposomal drugs for the treatment of COVID-19 in website all3 under 10906 Project ID : 47-2020-10906

Dr. Thomas Kallimopoulos posted this:
CEO at Extranthis UG

Process of extraction of Alkaloid drugs from biomass using sustainable extracting solvent Our developed technology relates to the use of vegetable oil, a sustainable and green material, for the extraction and production in large scale of specific and highly useful alkaloid drugs as Active Pharmaceutical Ingredients (API), from biomass.

Yissum - Research Development Company of the Hebrew University posted this:

Systematic Computational Drug Repositioning to Treat COVID-19 Systematic Computational Drug Repositioning to Treat COVID-19 Project ID : 47-2020-10880

LUCIA CORAL posted this:
Knowledge Tranfer Manager at National Cancer Institute CRO Aviano

Cell models to evaluate activity of p53:MDM2 inhibitors Twist GAIN-of-function and LOSS-of-function cell models were developed and used for preclinical p53:MDM2 inhibitors evaluation, preliminary demonstrating that the expression of Twist hampers their efficacy. These findings support patient stratification on the basis of twist expression for treatment of a large fraction of sarcomas but also of a fraction of carcinomas. (Piccinin et al., Cancer Cell, 22, 404-415, Sept 11 2012).

Udit Mangal posted this:
Vice President- Business Development at Pluss Advanced Technologies Pvt. Ltd.

Phase Change Material Based Temperature Control Solutions for biological samples, test kits and vaccines At Pluss, we bear distinction of doing innovative and sustainable solutions in the field of temperature control using our core Phase Change Material (PCM) technology. One of our lead products is Celsure®, a set of pre-qualified shipping boxes for maintaining the temperature of your vaccines or other heat labile products for up to 120 hours between 2-8 deg C, 15-25 deg C and frozen (-20 deg C) as the case may be, with a variety of payload volumes (https://www.pluss.co.in/celsure/). Besides the prolonged back up hours, the unique design of the solution allows for complete freeze prevention way of storing vaccines in case of 2-8 temperature maintenance.

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