Biology / Biotechnology Technology Offers

Yissum - Research Development Company of the Hebrew University posted this:

Diagnosis & Rehabilitation of Language Disorders in Children, Using a Self-Operated Tablet Based App Diagnosis & Rehabilitation of Language Disorders in Children, Using a Self-Operated Tablet Based App Project ID : 19-2019-8746

Yissum - Research Development Company of the Hebrew University posted this:

Enhanced Secretion of Proteins by Tag-Cleaving Cellular System Enhanced Secretion of Proteins by Tag-Cleaving Cellular System Project ID : 6-2019-8747

Ivan Rodriguez Rosello posted this:
Licensing Manager at Universidad de Alicante

Antibacterial alternative to antibiotics, with high specificity against Escherichia coli The "Molecular Microbiology" research group at the University of Alicante has modified several phage proteins (Poll-N and UK-C) that have high specificity against Escherichia coli (E. coli), but not against other Gram-negative (G-) bacteria. For these reasons, their use as a specific antimicrobial against E. coli is potentially interesting, especially in the case of contaminated food, cosmetics or water. It would also be useful in the treatment of diseases (infections) caused by E. coli. The presence of a histidine tail attached to the phage proteins not only facilitates their purification but also improves lysis efficiency without the need of cell permeabilization treatments. Companies interested in the commercial exploitation of the technology through license agreements and/or technical cooperation are sought.

Antibacterial alternative to antibiotics, with high specificity against Escherichia coli

University of Vigo posted this:

Valorization of whey and vinasses by producing antimicrobial extracts using biotechnological processes This invention is based on the production of antimicrobial extracts with potential application against pathogenic microorganisms. The biotechnological production of antimicrobial metabolites was carried out using Lactobacillus plantarum strains. Two industrial wastes, whey, and wine distilled lees (or vinasses) were assayed in order to make the process economically competitive with regard to the chemical one. The extracts are mainly composed by lactic acid, 3-phenyllactic and bacteriocins. Whey was enzymatically hydrolyzed and the solutions were fermented sequentially or simultaneously. The bioprocesses were carried out continuously or discontinuously

jaume mir posted this:
CEO at Biochemize SL

Production of D-panose through an innovative microbial fermentation process D-panose (α-D-Glucopyranosyl-(1->6)-α-D-glucopyranosyl-(1->4)-D-glucose) is a high value tri-saccharide molecule that has been proposed as a low caloric content sugar (i), as a promoter for probiotics (ii) and having outstanding anti-oxidant. anti-tumoral properties (iii). Currently this rare sugar is obtained by chemical synthesis, and this is the reason for its extremely high cost/ price (1) and poor industrial uses (2). At Biochemize SL we have developed a (very simple) production process that leads the production of high pure (more than 99%) D-panose, through a microbial fermentation process using a recombinant bacteria strain engineered by us, at a significantly lower operational/production cost. We offer this process to be operated by/ be licensed to a manufacturing company operating in this area.

Production of D-panose through an innovative microbial fermentation process

University of Granada (OTRI) posted this:

Method for diagnosing Hereditary Hemorrhagic Telangiectasia (HHT)Hereditary Hemorrhagic Telangiectasia (HHT) is a rare and genetic disease in which a disorder in angiogenesis exists. A new method for the molecular diagnosis of this disease has been developed. It is based on the quantification of a set of microRNAs (miRNAs) transported by plasma exosomes, and in addition, this set allows diagnosing different variants of the disease. This new method has the advantage of providing new biomarkers that allow a rapid and reliable diagnosis of HHT, since the current methods are not valid for all the patients affected with HHT.

Method for diagnosing Hereditary Hemorrhagic Telangiectasia (HHT)

UACOOPERA University of Aveiro posted this:
Technology Transfer Office at uacoopera

MAGNETIC NANOPARTICLES FOR TEMPERATURE-CONTROLED MOLECULE AND CELL SEPARATION AND DETECTION Coated and functionalized magnetic nanoparticles for e.g. detection and separation of DNA and RNA, protein purification, cell separation and immunoassays, con-trolled by temperature. Contrary to state-of-art mag-netic nanoparticles presently used for separation, which always present a certain degree of aggregation, the present technology proposes nanoparticles with tem-perature-controlled magnetic response. The magnetic response of these new nanoparticles is suppressed at higher temperatures (tunable between 40°C and 100°C) avoiding aggregation and is enhanced at lower temperatures promoting separation.

MAGNETIC NANOPARTICLES FOR TEMPERATURE-CONTROLED MOLECULE AND CELL SEPARATION AND DETECTION

UACOOPERA University of Aveiro posted this:
Technology Transfer Office at uacoopera

Immunoglobulin Y Purification, Its Products And Uses This invention describes a purification process of immunoglobulin Y from egg yolk in three stages, by applying precipitation methods, liquid-liquid extraction and ultracentrifugation. The present process allows to obtain immunoglobulin Y of high quality and with a purity >95%, in a simple and economic way, and applicable at an industrial scale.

Immunoglobulin Y Purification, Its Products And Uses

Consejo Superior de Investigaciones Científicas posted this:

Benzothiazole Derivatives as CK-1 Inhibitors for the Treatment of Amyotrophic Lateral Sclerosis CSIC has synthesized a family of benzothiazoles which acts as casein kinase 1 (CK-1) inhibitors. Therefore, these compounds are useful for the treatment of diseases related to circadian rhythm and neurodegenerative, inflammatory, autoimmune, neurological and psychiatric diseases where CK-1 is relevant. Furthermore, these compounds induce cell regeneration. Pharmaceutical companies interested in a patent licence are sought for.

Benzothiazole Derivatives as CK-1 Inhibitors for the Treatment of Amyotrophic

Consejo Superior de Investigaciones Científicas posted this:

Microorganism and method to produce urolithins Professor Francisco Tomas group at CEBAS-CSIC has isolated and characterized the first urolithins- producing microorganism from ellagic acid and ellagitannins present in the diet. A urolithin producing method based on the use of the mentioned microorganism has been developed and both, the microorganism and the method are part of a Spanish priority patent application assigned to CSIC. Biotech companies, functional food or nutraceutical companies are sought for license and/or development agreements. An offer for Patent Licensing

Microorganism and method to produce urolithins

Consejo Superior de Investigaciones Científicas posted this:

OPTOBIOTICS: Novel antibacterial proteins activated by blue light CSIC has developed a chimeric protein that, when expressed in bacteria, changes its structure upon absorption of blue light, thus generating protein aggregates (amyloids) that inhibit bacterial growth Industrial partners from the pharmaceutical industry are being sought to collaborate through a patent licence agreement An offer for Patent Licensing

OPTOBIOTICS: Novel antibacterial proteins activated by blue light

Consejo Superior de Investigaciones Científicas posted this:

Continuous indoor rearing of Philaenus spumarius, the main European vector of Xylella fastidiosa CSIC has developed a methodology to rear the meadow spittlebug Philaenus spumarius (L.) (Hemiptera, Aphrophoridae) in control climatic conditions in the laboratory allowing the supply of nymphs and adults before they become available in the field. This continuous indoor-rearing protocol could facilitate studies on the biology, ecology and management of P. spumarius and on the transmission of Xylella fastidiosa. Innovative and research partners from the agro sector are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing

Continuous indoor rearing of Philaenus spumarius, the main European vector of Xylella fastidiosa

Consejo Superior de Investigaciones Científicas posted this:

Identification of particles and/or cells in suspension using a mechano-optical system CSIC has developed a sample analyzing system that can identify particles and/or biological cells in aqueous suspension or in physiological medium. The system allows simultaneously measuring the mass and light scattering of the particles in suspension in real time. This technology has been used to distinguish different cell lines, making it useful for diagnosing diseases. Industrial partners manufacturers of lab equipment are sought to collaborate through a patent license agreement. An offer for Patent Licensing

Identification of particles and/or cells in suspension using a mechano-optical system

Yissum - Research Development Company of the Hebrew University posted this:

Novel Naturally Occurring Compounds for Treating Cystic Fibrosis Cannabis project Derivatives of cannabinoids have an antimicrobial and anti biofilm effect on pseudomonas and candida which are major ethological pathogenic factors in CF Project ID : 6-2019-6720

Yissum - Research Development Company of the Hebrew University posted this:

Platform for Neutrophil Specific Targeting as a Mode of Immunotherapy Dr. Zvika Granot, from the School of Medicine-IMRIC-Developmental Biology and Cancer Research, is working on a innovative approach for Neutrophil specific targeting of TGF-beta signaling as a novel anti-cancer therapy (see attached summary and several papers) Project ID : 6-2015-4241

Platform for Neutrophil Specific Targeting as a Mode of Immunotherapy

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