Biology / Biotechnology Technology Offers

Universidad de Granada posted this:

Novel luminescent probes of lanthanide complexes for sensing of biomolecules.A research institution and a university from Spain have developed a new family of antenna chromophores able to sensitize effectively luminescence of lanthanides to be applied as labelling probes for biomolecules. Industrial partners specialized in fluorescent probes for biological research are being sought to collaborate through a patent license agreement.

CNIC (TTO) posted this:
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)

New method for the diagnosis of atherosclerosis Inflammation is an active driver of atherosclerotic plaque development and a risk factor for atherosclerotic events. It is therefore of utmost importance to understand the mechanisms behind these inflammatory processes and to be able to develop new diagnostics and treatment modalities for atherosclerotic disorders. CNIC, FJD (Fundación Jiménez Díaz) and UAM (Universidad Autónoma de Madrid) researchers conducted a study to identify new antibodies that show reactivity against the atherosclerotic plaque. They have found that one of these antibodies recognizes a mitochondrial dehydrogenase of the proline metabolism (PRODH). The levels of this protein are increased in the plasma of atherosclerotic mice and humans with carotid disease, supporting the potential use of this PRODH as a biomarker for atherosclerosis.

Fabiola Moreno posted this:
Technology Licensing Assistant at Binghamton University

Novel Therapeutic Agent to Target Microbial Biofilms A naturally produced signaling molecule combats chronic and resistant hard-to-treat infections and contaminations by inducing microbial biofilms to disperse.

Novel Therapeutic Agent to Target Microbial Biofilms

Yissum - Research Development Company of the Hebrew University posted this:

Novel Blood Test for Early Detection of Alzheimer’s Disease Non-Invasive Detection of Brain Cell Death Using Methylation Patterns of Circulating DNA: A Novel Blood Test for Early Detection of Alzheimer’s Disease Project ID : 47-2020-10832

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

Catechol O‑Methyl Transferase Targeted Library OTAVAchemicals offers Catechol O‑Methyl Transferase (COMT) Targeted Library. It contains 504 compounds with predicted inhibitory activity against this enzyme. The library has been carefully designed with combination of ligand- and receptor-based pharmacophore modeling.

Catechol O‑Methyl Transferase Targeted Library

Leading Biology posted this:

Yeast Expression System Service Advantages of yeast expression system service in Leading Biology 1. Having a complete Pichia pastoris expression platform could design different experimental schemes according to customers requirements. 2. Having a high throughput screening platform could find the best expression conditions quickly and effectively. 3. Could do large-scale fermentation production.

Yeast Expression System Service

Covid-19 Innovation Challenges by Innoget posted this:

Viral RNA-dependent RNA Polymerases Viral RNA-dependent RNA Polymerases (RdRPs) Targeted Library (1259 compounds) with predicted activity against viral RdRPs is offered. It has been carefully designed using machine learning (artificial neural networks and Bayesian statistics

Viral RNA-dependent RNA Polymerases

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

Viral RNA-dependent RNA Polymerases Viral RNA-dependent RNA Polymerases (RdRPs) Targeted Library (1259 compounds) with predicted activity against viral RdRPs is offered. It has been carefully designed using machine learning (artificial neural networks and Bayesian statistics

Viral RNA-dependent RNA Polymerases

Covid-19 Innovation Challenges by Innoget posted this:

SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library OtavaResearch Institute group presents SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library (1031 in-stock compounds with predicted activity against SARSCoV2 (RdRpp)).

SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library OtavaResearch Institute group presents SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library (1031 in-stock compounds with predicted activity against SARSCoV2 (RdRpp)).

SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library

Leading Biology posted this:

Canine Monoclonal Antibody Service Canines are often used as animal models for vicious infection, inflammation and autoimmune diseases, especially some digestive system diseases. Based on rich experimental experience and technology accumulation of phage display, Leading Biology, with experience of large scale elutriation screening of high affinity dog mAb, has successfully established an immunization antibody library against several antigens. The antibodies prepared can be widely used in the biomedical field.

Covid-19 Innovation Challenges by Innoget posted this:

SARS-CoV-2 Papain-like ProteaseTargeted Library Using receptor based virtual screening OtavaResearchInstitute’s team designed the SARS-CoV-2 Papain-like Protease PLpro Targeted Library, which is contain 1058 stock compounds with predicted activity against this protease and ready for delivery.

SARS-CoV-2 Papain-like ProteaseTargeted Library

Covid-19 Innovation Challenges by Innoget posted this:

SARS-CoV-2 NSP16 Targeted Library SARS-CoV-2 2′-O-methyltransferase (NSP16) Targeted Library, which contains 1049 compounds with predicted activity against SARS-CoV-2 NSP16 is offered. The library has been designed with receptor-based virtual screening using crystal structure of SARS-CoV-2 2′-O-MTase (PDB ID: 6WKQ).

SARS-CoV-2 NSP16 Targeted Library

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

SARS-CoV-2 Papain-like ProteaseTargeted Library Using receptor based virtual screening OtavaResearchInstitute’s team designed the SARS-CoV-2 Papain-like Protease PLpro Targeted Library, which is contain 1058 stock compounds with predicted activity against this protease and ready for delivery.

SARS-CoV-2 Papain-like ProteaseTargeted Library

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

SARS-CoV-2 NSP16 Targeted Library SARS-CoV-2 2′-O-methyltransferase (NSP16) Targeted Library, which contains 1049 compounds with predicted activity against SARS-CoV-2 NSP16 is offered. The library has been designed with receptor-based virtual screening using crystal structure of SARS-CoV-2 2′-O-MTase (PDB ID: 6WKQ).

SARS-CoV-2 NSP16 Targeted Library

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