Biology / Biotechnology Technology Offers

Yissum - Research Development Company of the Hebrew University posted this:

Small Molecules as PPAR-DELTA Antagonist for Treatment of Metabolic Disorders PPAR-Delta may be a promising target and that is because its agonist (GW501516) has beneficial effects on obesity, insulin resistance, and reduces plasma glucose in rodent models of type 2 diabetes. Project ID : 6-2018-4546

Yissum - Research Development Company of the Hebrew University posted this:

Synthetic Cannabinoid Effect on Bacteria Communication new concepts in fighting both bacterial and fungal infections, accumulations and pathogenicity Project ID : 6-2018-4547

Yissum - Research Development Company of the Hebrew University posted this:

Novel Methods for Preparing Polymeric or Hybrid Microcapsules Using Oil-in-Oil Emulsions Novel Methods for Preparing Polymeric or Hybrid Microcapsules Using Oil-in-Oil Emulsions Project ID : 31-2016-4313

Yissum - Research Development Company of the Hebrew University posted this:

VEGF Stimulation for Anti-Ageing Treatment A treatment resulting in attenuation of multiple aging phenotypes ("healthy aging") and lifespan extension Project ID : 6-2018-4548

Yissum - Research Development Company of the Hebrew University posted this:

Blood Chip for the Identification of Cell Free DNA Cluster7 Cluster8 A diagnostic two-pronged approach to interrogate epigenetic modifications in cfDNA The assay simultaneously measures cfDNA methylation and covalent histone modifications of circulating nucleosomes, and develop analysis methods for inferring the rate of cell death, physiological state, and transcriptionally active pathways in originating tissues Keywords: Diagnosis, cell free DNA diagnosis, circulating DNA, liquid biopsies, methylation patterns, histone modification pattern, tissue of origin detection, cancer diagnosis, drug monitoring Digital Health Project ID : 6-2017-4530

Yissum - Research Development Company of the Hebrew University posted this:

SubQ - Semi-Automatic Device for Subcutaneous Injection a handheld semi-automatic device, that will pinch the skin and insert a needle under it at the right depth and angle. The user will only need to apply a clear plastic dressing over the needle to fix it in place. Project ID : 40-2018-4615

Yissum - Research Development Company of the Hebrew University posted this:

TEMPACE: A Temporary Pacemaker to Secure Transcatheter Aortic Valve Implantation (TAVI)Dual device comprised of a small temporary pacemaker that fits on top a standard pacing lead during the TAVI procedure itself and used to rapidly pace the heart during the procedure to prevent movement. Project ID : 40-2018-4616

Maria João Cardoso posted this:
Science and Technology Manager at UATEC - Unidade de Transferência de Tecnologia

Separation of nucleic acids using chromatographic matrices functionalized with ionic liquids Novel multimodal chromatographic supports prepared by functionalizing matrices with ionic liquids, allowing the separation of RNA and DNA in a single chromatographic step with high selectivity, robustness and reproducibility. In comparison to other commercially available supports, a higher dynamic binding capacity for RNA was obtained.

Avazyme posted this:

Food safety, quality, authenticity and consulting services Avazyme offers agile and custom problem solving services to the food industry through the application of biological and chemical analytics. Differentiated from larger CROs that offer a rigid standardized menu of services, Avazyme is focused first on agile problem solving. Avazyme has state-of-the-art instrumentation and methodologies. Problem solving is applied to food safety, quality, authenticity and GMO testing. Avazyme also offers consulting in food regulatory science, Maximum Residue Levels (MRLs), import tolerances and food safety, quality and secondary standards, nutritional labeling, authenticity and GMO analysis. Consulting in new assay development, validation and certificate of analysis is also offered. Differentiated from larger CROs, Avazyme offers nimble, rapid and custom analytical method development and validation. Offers include development of laboratory and point of use assays. Avazyme offers organizations Independent Lab Validation (ILV). Avazyme is BSL2, EPA GLP, FDA GLP compliant and will work with companies requiring GMP and ISO17025 standards.

Yissum - Research Development Company of the Hebrew University posted this:

UFREE: Indwelling Catheter for Natural Urination An endourethral catheter with no external parts that could lead to infection. The indwelling catheter allows the patient to urinate by gently pressing his penis, using a simple mechanical valve located inside the urethra. The device is inserted and extracted in a noninvasive way, similar to the procedure of using a standard catheter, and would be done by the patient himself in the home setting. Project ID : 40-2018-4617

Yissum - Research Development Company of the Hebrew University posted this:

New Target for the Treatment of Parkinson’s Disease The proposed invention is a novel target, Phophoinositides, for the treatment of Parkinson’s disease, based on a new mechanism, associating increased levels of membrane phospholipids with alpha-Syn-related toxicity. Key words: Parkinson’s disease; alpha-Synuclein; Phosphatidylinositol; phosphatidylinositol 4,5-bisphosphate (PI4,5P2); striosomes; axonal injury; axonal branching Project ID : 6-2018-4627

Yissum - Research Development Company of the Hebrew University posted this:

Liposomal Compositions of Glucocorticoids in Anti-Cancer Therapies (LC200)chemically modified gluococorticoids (GC), in their amphipathic weak acid form enables the effective loading in liposomes of the acidic GC. Surprisingly, the thus formed liposomal weakly acidic GC was stable, i.e. the majority of the substance remained within the liposome as intact acidic GC after storage for 14 months at 4?C. Once released from the liposome to water or body fluids the acidic GC was hydrolyzed to obtain the active, non-acidic GC. Project ID : 12-2006-1706

Yissum - Research Development Company of the Hebrew University posted this:

SUPERDOPA: A New Small Molecule for the Treatment of Parkinson Disease A novel anti-apoptotic slow-release L-Dopa precursor A small molecule (approximately the size of a tri-peptide) with multiple properties for treating Parkinson (for parkinson and anti biofilm) making the L-Dopa treatment last for many more years Project ID : 7-2014-2989

Yissum - Research Development Company of the Hebrew University posted this:

iCOUGH: Accumulative Breath Cougher for Spinal Cord Injuries The device incorporates an active drug delivery PEP valve device that provides active, accumulative dosing of large volume of aerosolized drug or air. This technology enables the distribution of the substance to the lower respiratory system. also incorporated is a Venturi-based insufflation-exhalation system that simulates cough by predefined parameters activated independently or by stimuli from the patient Project ID : 40-2018-4614

Yissum - Research Development Company of the Hebrew University posted this:

CloneSEQ: 3D Cell Growing and Clone-Level Sequencing Methods CloneSeq is a drop-based microfluidic system for single cell genomics. CloneSeq facilitates expansion of single-cell-based colonies in 3D micro-beads that can later be disassembled and extract nucleic acid material, compatible with DropSeq genetic sequencing technologies Keywords: Genomics, Single-cell RNA-sequencing, single-cell transcriptomic profiling, single-cell technologies, genomics, RNA sequencing, microfluidics, circulating tumor cell, CTC, cancer stem cells, dropseq, 3D culture, Cancer genetics, Cancer genomics, High-throughput screening, Sequencing Project ID : 6-2017-4524

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