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Germans Trias i Pujol Health Sciences Research Institute (IGTP) posted this:Diagnostic biomarkers for dementia with Lewy BodiesThe present data provide a solid basis for the development of genetic biomarkers for the early identification of patients suffering from dementia with Lewy bodies and to classify them into specific molecular subtypes. One of the biomarkers correlates with the development of Lewy pathology in the brain and may be useful to monitor the success of possible alpha-synuclein antiaggregatory therapies.
Universitat de Lleida posted this:New method to increase yolk color and egg nutritional qualityThe University of Lleida seeks industrial partners with expertise in the sector of crop production to adopt a new technology of optimized feed solution for egg producers (poultry market). The type of partner sought is for the regulatory codevelopment and commercialization of our solution under a technology license agreement.
Creative Biolabs posted this:Constrained Peptide Library ConstructionCreative Biolabs developed a constrained peptide library construction technology, which offers constrained peptides with target-adapted cross-links. Our technology involves generating natural or semi-synthetic peptides with constrained structures to retain and improve the properties (e.g. stability, resistance to protease activity, protein binding affinity, intrinsic cell permeability, etc.) of the peptides.
Creative Biolabs posted this:Internalizing Antibody Screening ServiceCreative Biolabs now offers high-throughput screening service of internalizing antibodies to our customers around the world. Integrated with multiple leading-edge technology platforms, we can guarantee our clients with the most efficient and reliable service to isolate antibody candidates with internalization potential against various membrane targets.
Creative Biolabs posted this:Phage Display Library Screening ServiceAs a well-recognized expert at phage display technology, Creative Biolabs offers our worldwide clients the best phage display library screening services through our excellent biopanning strategies and state-of-the-art equipment. Our scientists are pleased to tailor the most appropriate strategies to screen the interested libraries of our customers.
Technology Transfer Office
TTPU posted this:Anti-adhesive Biopolymer CoatingResearchers have developed an anti-adhesive coating based on a polymer naturally and sustainable produced by a marine bacterium. This coating prevents the bacterial adhesion and the subsequent biofilm formation that usually leads to host bacterial infections difficult to eradicate and control with the antibiotics currently in use, namely in hospital environments. This coating can be applied in a cost effective way to a broad range of materials through the application of a universal glue.
Alfonso del Rey Pérez posted this:
Licensing Manager at Institut Català de Nanociència i Nanotecnologia
University of Granada (OTRI) posted this:Dual Probes for Flow Cytometry and Mass CytometryResearchers of the University of Granada have developed probes based on nanoparticles, both fluorescent and functionalized with metals, which act as dual probes, and can be used for both flow cytometry (FACS –Fluorescent-Activated Cell Sorting) and mass cytometry (CyTOF -Cytometry by Time-Of-Flight-). The probes can be used for bar coding of living cells or carrying out in vivo studies of different cell lineages through cell co-cultures as well as the activation of drug precursors through cytoplasmic catalysis of organometallic reactions inside living cells.
Research & Technology Organization
UNIVERSIDAD DE ALICANTE posted this:Innovative process of integrated culture of marine speciesResearchers at the University of Alicante have developed a procedure that combines the culture of several marine species in the same place in offshore areas, as part of an integrated multi-trophic aquaculture (IMTA) system. The main culture may be any of the species commonly used in marine aquaculture as fed fish or shellfish, and the second one involves the culture of amphipods that feeds on organic waste generated by the main culture and has an important commercial potential as food resource. The main advantage of this technology is the cost-effectiveness of implementing this procedure in sea cages because with the same investment and infrastructure is raising an additional species reusing existing waste and diversifying production. Thus, it can be used in the industrial sectors of aquaculture. The research group is looking for companies acquiring this invention for: commercial agreement or technical assistance or manufacturing agreement or technical cooperation or a combination of some of these services.
University of Huelva posted this:New procedure for the genetic transformation of plant cells and kit for carrying out said methodThe strategy for transformation is extremely simple and does not involves subcloning the gene of interest in any vector. The kit is not based on specific promoters or regulatory DNA sequences, thus it can be applied to many different plant species, from unicellular microalgae to higher plant protoplasts. Since the strategy is not based on specific promoter or regulatory DNA sequences, only the marker and the gene of interest sequences are inserted in the microalgal genome, avoiding the introduction of undeserible DNA sequences in the transformant strain. This is very important given the concern that transfer of exogenous DNA through transgenesis causes in the public opinion
Universitat de Lleida posted this:LapC-FORCE: Surgical device to improve laparotomy closure for incisional hernia preventionA multidisciplinary team involving doctors and engineers developed a medical device to cover the surgeons’ need at the moment of closing a laparotomy. With real-time information on force and distance, surgeons may decide the most appropriate closure technique and materials to be used for each single patient for reducing the laparotomy’s closing force and therefore, to prevent incisional hernias. We currently have a prototype medical device that measures the closing force between edges in a laparotomy. It was designed and tested in non-regulatory preclinical trials using pigs. We are looking for an industrial partner with expertise in the sector of medical devices willing to add in its product pipeline a new surgery device to assist surgeons during a laparotomy. The type of partner sought is mainly for regulatory development and commercialization under a technology license agreement.
Benemérita Universidad Autónoma de Puebla posted this:BACTERIAL FORMULATION FOR PLANT GROWTH.The present invention includes a bacterial formulation that contains 6 different bacterial strains: Azospirillum brasilense Sp7, Burkholderia unamae MTI641, Pseudomonas putida KT2440, Sphingomonas sp. OF 178, Gluconoacetobacter diazotrophicus PAI 5 and Bradyrhizobium sp. MS22, able to promote the growth in plants of agricultural and/or bioremediation interest. The formulation promotes the growth of maize plants and other plants of agricultural interest. The bacteria of the present invention are adhered and may colonize the plants in a suitable manner by means of their own capacities.
University of Granada (OTRI) posted this:New forms for controlled drug release composed by proteic hydrogel crystalsScientists from the University of Granada in collaboration with the Spanish National Reseach Cuncil (CSIC) have developed a procedure for fabricating a composition made with a hydrogel that contains crystalized proteins with pharmacological activity with a medium size of 12 microns, that can be even smaller up to 5 microns. The group has focused their work with insulin, though other proteins with therapeutic interest can be used. In any case, the crystalized proteins with pharmacological activity grow in situ inside de hydrogel.
Research & Technology Organization
Universidad de Alcalá-OTRI posted this:Metal nanoparticles stabilized with carbosilane dendrons for the treatment of infectious diseases and cancer.The research group in “Dendrimers for biomedical applications” of the University of Alcalá, in collaboration with researchers form the Foundation for Biomedical Research of Gregorio Marañón Hospital in Madrid, present the first example of dendronization of metallic nanoparticles with dendritic systems of ionic carbosilane nature. Also the present invention relates to the method of obtaining these nanoparticles and the use of the mentioned compounds for the treatment of infectious diseases or cancer. The researchers seek for collaboration agreements, licensing or commercial agreements with technical assistance, with companies or institutions from the biomedical sector.
Pragmatec posted this:Chitosan-based wound dressing for diabetic foot ulcer treatment and burn woundsChitosan-based wound dressing that stimulates the closure, neovascularization and permanent regeneration of dermis in diabetic feet’s ulcers. It reduces the risk of amputation in patients.This innovation can also be used to prevent or treat wound and burn infections, not only due to its intrinsic antimicrobial properties, but also due to its ability to deliver extrinsic antimicrobial agents to wounds and burns. Additionally, it can be used as a slow-release drug-delivery vehicle for growth factors to stimulate and improve wound healing. This technology offers a complete regeneration of the ulcer using a single copy of the material without the need for invasive treatment, ensuring no backsliding in the development of ulcers. The purification process triggered by the chitosan and the ensuing chemical modifications in the membranes reduce possible allergic reactions and maximize the benefits, such as its antibacterial effects.