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Universidad de Alcalá-OTRI posted this:
Novel method for the detection of adulteration of saffron with gardeniaResearchers from the (Micro)-Separation Techniques Research Group of the Department of Analytical Chemistry, Physical Chemistry and Engineering of the University of Alcalá has developed a procedure for the detection of adulterations of saffron with gardenia based on the detection of geniposide by Liquid Chromatography with High–Resolution Mass Spectrometry detection. The procedure allows to detect adulterations with gardenia in an unambiguous and sensitive way. A problem not solved at present by any other existing methods. The group is looking for companies in the agro-food sector to sign technical cooperation agreements, commercial agreements with technical assistance or patent licensing agreements.Universidad de Alicante posted this:
Novel method to fabricate highly selective sensors for different substances of interestThe research group "Electro catalysis and Electrochemistry of Polymers", Department of Physical Chemistry at the University of Alicante has developed a novel method that allows highly selective electrode manufacture biometrics to detect any biochemical substance of interest, food or environmental. The method is based on the electro assisted deposit of molecularly imprinted silica layers on different electrodes. This allows a fast and efficient detection of the molecule of interest, independently of the other interfering. In addition, allows the regeneration of the electrode in a very simple way and lets its usage almost indefinitely. Innovative aspects The biometrical electrode manufacturing method is based on a electro assisted method of molecularly imprinted silica layers on different electrodes. With this new procedure, we obtain uniform and consistent layers of silica that allow highly selective detection of any biochemical substance of interest, food or environmental when these electrodes are used as amperometric, voltammetric, impedimetric and potentiometric sensors. Main advantatges of the technology The main advantage of the electro assisted deposit respect to conventional methods of thin film deposition (spin-coating or dip-coating), lies in the control of consistency and porosity of the layers. Due to the prevention of uncontrolled pore formation, avoids the indiscriminate passage of species from the solution to the electrode surface, reducing the interference in the detection of the analyte of interest. It has a high specificity and affinity for the molecule of interest. High control on the deposition of silica when is done by electro assisted mode. The possibility of varying the thickness of the silica layer and layer morphology allows for a highly consistent and reproducible layer. Electro assisted deposit method is capable of "self-healing", i.e. prevents the formation of holes in the assisted layer that interfere with the detection of the molecule of interest. With continued use, the sensor loses its effectiveness by the collapse of the pores with the species to be determined. In this case, the regeneration process is very simple: just repeat the procedure for removing the template molecule to be performed after the gel layer (electrochemical extraction or cleaning solvents). Thus, the pores of the sensing phase are released for use again.Universidad de Alicante posted this:
Novel method to increase production and extraction of phytosterolsThe research group "Proteomics and functional genomics of plants of the University of Alicante has developed a new procedure that increases the production and extraction of phytosterols in plant cell cultures in vitro. To do this, is added to the culture medium cyclodextrins and optionally methyl jasmonate. After growing under certain conditions, phytosterols are obtained with yields higher than the current extraction techniques from the plant material. This method allows a stable production of phytosterols, independent of geographical, seasonal and environmental factors, with reduced spaces requirements and easier process of purification and industrial scaling. The group is looking for companies interested in acquiring the technology for commercial exploitation. Innovative aspects Nowadays, the classical method of extracting phytosterols from vegetable raw materials has a very low yield. This, combined with the large amount of plant material needed to extract a significant amount of phytosterols from global natural sources (only could be supplied 10% of Western populations), causes a high cost of these products. With this new process of in vitro plant cell culture, it is possible to increase production and efficiency of extraction of phytosterols from natural resources for a greater percentage of the population that could benefit from the positive effects of phytosterols on health.Unitat de Valorització de la URV posted this:
Novel Model of Multi Stages Ducted Horizontal Axis Wind Turbines StructureInvestigate and design a new structure of ducted horizontal axis wind turbines ordered in a line with an integrated passive flow control mechanism to vortices generation behind ducted wind turbines and to achieve optimum performance in wind energy harvesting in regions with low wind speed. The ducted wind turbines in the proposed design can be a big additive to other renewable energy sources and can be an alternative to the less efficient common types of wind turbines since they are adaptable to environments and produce higher amounts of energy, which makes use of wind energy as a clean, practical, economical, and environmentally friendly available alternative. The diffuser-augmented wind turbine (DAWT) turbine is being looked at as a way to increase the production of wind energy in low wind speed regions. The proposed design will be a good solution as: 1. Producing a maximum possible limit of energy in regions with low wind speeds that consider one of the challenges that restrict spreading techniques generation of energy from wind in mentioned regions. 2-Work as a micro-compact wind farm, which can be suitable for installation in small areas; the common types of wind farms with horizontal axis wind turbines need a large area to be installed because of the wake phenomenon behind wind turbines. 3. The proposed model will be friendly to wildlife and birds, and it will operate with a minimum limit of noise. 4: A suitable solution to support energy systems in buildings, trains, long vehicles, and ships as a source for energy in remote areas, as renewable energy, and as a supporter for efforts to reduce the dependency on fossil fuel sources.
Licensing Manager at Fundació URVUniversitat Politècnica de Catalunya - UPC posted this:
Novel motion nanosensor based on mechanical amplificationIn the past years there is an increasing interest to incorporate in any electronic device a motion sensor to provide interaction: measuring our reactions, position or motion. Therefore, the motion sensors should be low-cost but more precise. A nanosensor based on a motion amplifier mechanism is presented. The design can amplify extremely small displacements (nanometers) up to 200 times. Partners to further develop the system and/or to establish commercial agreements along with technical cooperation are sought.Universidad de Alicante posted this:
Novel procedure for polymeric foams with various applications from waste plastics.The research group "Processing and Pyrolysis of Polymers", Department of Chemical Engineering at the University of Alicante has developed an innovative process that allows recycling of different types of plastics (EVA, polyethylene, polypropylene, polyurethane, polymer melt, foam, rubber or any combination thereof) to transform in a simple and economical ways products with applications in various industrial sectors. The group is looking for companies interested in acquiring the technology for commercial exploitation. Innovative aspects The inclusion of waste plastic (EVA, polyethylene, polyurethane, polypropylene, polymer melt, foam, rubber, etc. Or any combination thereof) in the composition, permits its recycling in a simple and cheap, and that current procedures are difficult and very expensive. Together with a chemical foaming and dispersion of ferrites in the composition, applies the energy necessary for the cohesion of the materials by microwave. Ferrites dispersed in the mixture capture and transmit microwaves heat required for foaming in every part of the obtained mass. With this new procedure, getting pieces of great uniformity, stability and thickness that determines the user (up to 25 cm. in diameter) at a low cost and quick way.Innovation APTA posted this:
Novel Pseudomonas Strain for the Treatment of Iron-Deficient SoilProduction of pyoverdine,a type of siderophore, applicable as biofertilizer to reduce iron deficiency and the chlorosis induced by it. it also demonstrated an increase in plant growth due to higher iron bioavailability. Siderophores can act as efficient activators of induced systemic resistance systems in plants, as well as protect the plant from different pathogens.
Innovation Analist at Hub APTA
Fundacion Miguel Servet - NavarrabiomedFundacion Miguel Servet - NavarrabiomedFundacion Miguel Servet - NavarrabiomedNot defined
Fundacion Miguel Servet - Navarrabiomed posted this:
NOVEL SARS-CoV-2 VACCINE CANDIDATES WITH ENHANCED EFFICACY AND SAFETYCurrent vaccines to protect against SARS-CoV-2 rely on the immunogenicity conferred by the viral Spike protein, the main viral target against which the elicitation of neutralizing and protective antibodies is intended through vaccination. The Spike presents an extremely high affinity for the human ACE-2 (Angiotensin Converting Enzyme-2) receptor, which has been reported to be expressed in diverse layers of the organism, such as the epidermis, endothelium, muscle and sweat glands. Such a strong affinity between both proteins, the Spike and ACE-2, might lead to the retention of the immunogen and a suboptimal distribution to reach the lymph nodes, key for a robust immune response. Thus, we propose modifications in the SARS-CoV-2 Spike vaccine protein that reduces the affinity for ACE-2 while preserving key epitopes for elicitation of neutralizing antibodies. This technology lies in minimal modifications of the Spike protein sequences that reduce ACE-2 binding, leading to the aforementioned proposed advantages at the immunological level in this new vaccination strategy. To date, accurate biochemical experiments to show a reduced ACE-2 binding capacity for our vaccine candidates have been carried out to demonstrate the viability of the proposed solution, the results of which have been surprising in terms of confirming the initial hypothesis.Georgetown University posted this:
Novel Selective Angiotensin II Receptor Antagonists for Hypertension Treatment- A novel peptide (PEP7) selectively targets the Ang II signaling pathway to help with the management of hypertension - Selective inhibition of the Ang II signaling pathway reduces adverse side effects often associated with hypertension treatment - May help to improve existing hypertension therapies and increase patient complianceUniversidad de Alicante posted this:
Novel self-expanding polyurethane foams intended for inert filling of pleural and other human cavities.The Adhesion and Adhesives Laboratory of the University of Alicante has developed a new polymeric foaming material for in-situ filling and sealing of internal irregular different shaped human cavities, intended for patients suffering chronic pleural cavities and in-field injuries caused by bullets or accidental event leaving open blood vessels. The new foam is composed of two separate liquid components that can be mixed in a two-body syringe in such a way that the foaming time can be modulated for allowing the foam formation at the end of the syringe needle. The new polymeric foam can self-expanded and self-modelated for avoiding complications in open internal cavities caused by infections, blooding, fistulae, dyspnea or sepsis. The new foam is easily applicable, safe for biological tissues, and its use avoid the use of the current aggressive treatments in pleural cavities. It is looking for companies interested in acquiring this technology for its commercial exploitation.Universitat Politècnica de Catalunya - UPC posted this:
Novel sensor for in vivo nano-mechanical characterizationA nanoforce sensor has been designed to be able to work in aqueous environments. The system is based on a motion amplifier mechanism that allows to amplify extremely small displacements (nanometers) up to 200 times, providing the possibility to characterize the mechano-transduction mechanisms either of a single cell or a tissue in a 3D gel scaffold. Partners to further develop the system applying to specific assays and/or to establish commercial agreements along with technical cooperation are sought.Unitat de Valorització de la URV posted this:
Novel solar photothermal system for seawater desalination and superheated steam generationThe conversion of light-to-heat for steam production is an emerging technology that can be used for several purposes such as seawater desalination, sterilization, hydrogen production and electricity generation. The performance of solar photothermal steam generation (SSG) depends basically on the generation of localized heat on the surface of photothermal materials that can intensify the yield of heated steam under plausible solar intensity. The present invention provides a novel protocol for the generation of superheated steam under low solar intensity by designing a simple and low-cost photothermal system. It is composed of hydrophilic water supply cellulose fibre tube with head coated with innovative clay modified activated carbon/CuO. Black materials are commonly used as photothermal. This special SSG configuration shows outstanding superheated steam which reaches up to 160.9°C under half sun, which has never been reported in non-pressurized mode.
Licensing Manager at Fundació URVUniversidad de Alcalá-OTRI posted this:
Novel Synchronization Process for Multi-carrier or Single-carrier CommunicationsThe research group “Communications, Multirate Systems, and Biomedical Engineering” of the University of Alcala presents a novel synchronization procedure for multicarrier or single carrier systems for narrowband and broadband communications. This procedure allows a precise estimation of the symbol timing offset (STO), and a coarse estimation of carrier frequency offset (CFO). The procedure is based on the inclusion of symmetric extensions in the transmitted symbols for the synchronization, which makes it useful not only for communications systems based on the discrete Fourier transform, but also for transceivers based on the discrete cosine transform (DCT). Among its main applications are communications through single-mode optical fiber, powerline communications, wireless and wireline systems, and in general, all the techniques that use multicarrier and single carrier modulations. The group seeks companies from the telecommunications sector to sign technical cooperation agreements, commercial agreement with technical assistance and patent licensing agreements.Universitat Politècnica de Catalunya - UPC posted this:
Novel syringes and concepts for homogeneous injection of bone cementsNovel syringes and concepts useful for homogeneous injection of ceramic bone cements have been patented and developed. These new designs solve the current problems related to the press-filtering that limit the clinical applications. Partners to further develop the technology and/or to establish commercial agreements along with technical cooperation are sought.
PhD Isabel Gavilanes-Perez (RTTP)Spanish National Research CouncilPhD Isabel Gavilanes-Perez (RTTP)Open Innovation Manager at Spanish National Research Council
View ProfilePhD Isabel Gavilanes-Perez (RTTP) posted this:
Novel technology affordable for developing new stretchable opto-mechanical devices with larger mechanical tunability, versatility and sensitivityResearchers from Spanish National Research Council (CSIC), Catalan Institute of Nanoscience and Nanotechnology (ICN2-BIST), Biomedical Research Centre Network (CIBER) and Catalan Institution for Research and Advanced Studies have recently developed the first stretchable plasmonic enhanced wrinkled Fabry-Perot cavities showing extremely high sensitivity to mechanical deformations. This novel technology enables developing new stretchable opto-mechanical devices with higher mechanical sensitivity, tunability and versatility. Manufacturers in the field of sensors for detection of mechanical deformations, pressure or forces are being sought to collaborate and/or exploit the existing know-how through a patent license agreement.
Open Innovation Manager at Spanish National Research CouncilCracow University of Technology posted this:
Novel transparent polymer nanocomposites based on PMMA and inorganic semiconductor nanoparticles for optoelectronics applicationsA method of preparing novel and transparent polymer nanocomposites based on a polymeric matrix of polymethyl methacrylate (PMMA) and the inorganic nanoparticles of zinc sulfide doped with manganese atoms (ZnS:Mn).Georgetown University posted this:
Novel Treatments Targeting Drug-Resistant Prostate Cancer Cells- Novel small molecule carbazole compounds effectively inhibit androgen receptor signaling, overcoming resistance to current prostate cancer treatments. - Broad efficacy against castration-resistant and enzalutamide-resistant prostate cancer addresses critical unmet needs in advanced disease. - Potential applications extend beyond prostate cancer to other androgen receptor-positive cancers, including breast, ovarian, and fallopian tube cancers.University of Szeged posted this:
Novel types of C-3 substituted kynurenic acid derivatives with improved neuroprotective activityNeurodegeneration may occur when the brain is exposed to high level of reactive oxygen species, mitochondrial dysfunction, neurotoxicity, such as excitotoxicity. Administering neuroprotective agents can prevent the chronic conditions damaging nerve cells. Therefore, there is an urgent need to develop effective neuroprotective agents.Sayali Warad posted this:
NOVEL VISCOELASTIC MODEL FOR ENHANCED OIL RECOVERY AND RESERVOIR SIMULATIONA predictive model for polymer behavior. It can be used for recovering oil from a depleted oil reservoir and for screening polymers. Companies using this technology will have the ability to significantly increase the accuracy of polymer screening for injectivity and oil recovery operations, as well as the accuracy of numerical reservoir simulation.
IP Market Analyst at University of Alberta, Technology Transfer ServicesUniversidad de Alicante posted this:
Novel visual inspection system for quality control in production procesessVisual inspection systems are based on the employment of pictures, both in the visible and infrared or ultraviolet spectrums. They can also make use of sonar images or adding structured light to the environment in order to analyze defects and shapes in products. The figure shows an image obtained by means of a range camera that allows distinguishing an object by its depth. Thus, its position and defects can be determined through its volume. The technology is totally developed and has been laboratory and field tested, although, it requires a particular specification for each case. The technology can be used for real-time inspection of production processes, both for the recognition and for the classification and quality inspection.Georgetown University posted this:
NSG prolactin humanized mouse model to evaluate therapeutic strategies of ER+ breast cancerResearchers at Georgetown University and the University of Nebraska have developed a humanized mouse model expressing the human prolactin gene, to better study ER+ breast cancer. Current models do not properly represent the hormonal environment seen in patients. Furthermore, mouse prolactin fails to activate human prolactin receptors in xenograft experiments, ultimately selecting for prolactin-independent tumor growth and differentiation. This model overcomes these limitations by replacing the mouse prolactin gene, with a knock-in of human prolactin, therefore mimicking the hormonal environment of breast cancer patients. Crossing these mice with immunodeficient strains, allows for human cell transplantation and engraftments to reliably study ER+ breast cancer. BACKGROUND High levels of circulating prolactin have been associated with an increased risk of breast cancer. Together with ER and PR, prolactin plays a crucial role in breast development, influencing both mammary cell proliferation and differentiation. Although prolactin receptors are expressed in the majority of breast cancers, current mouse models fail to account for the hormonal environment seen in patients. In these models, human prolactin is not sufficient to activate mouse prolactin receptors, while mouse prolactin acts as an antagonist to the human prolactin receptor. The NSG-Pro mouse overcomes these issues by expressing the human prolactin gene allowing for physiological levels of circulating human prolactin, and therefore more reliable assessments of disease progression and drug response.
Innovation OfficeUniversity of GalwayInnovation OfficeAccelerates research impact, empowers start-ups and engages for innovation. at University of Galway
View ProfileInnovation Office posted this:
NucleoSeq Based Bacterial Detection: Fast, Precise, and ReliableBacterial infections remain a major global health challenge, requiring accurate and rapid diagnostic methods. Traditional detection techniques can be slow and cumbersome, often relying on lengthy culture times. Innovative approaches with high specificity and sensitivity are needed to improve detection speed and reliability. This technology addresses that need by targeting a widely conserved bacterial marker, enabling efficient and precise bacterial identification across various sectors.
Accelerates research impact, empowers start-ups and engages for innovation. at University of GalwayMeghan Meyer posted this:
NUT midline carcinoma cell lines TC797 and TC1297- NMC cell lines from the pleural fluid and bone marrow aspirate of a pediatric patient diagnosed with thymic carcinoma. - Unique karyotypic abnormality, an original viable cell line from a pediatric patient (1997). - Potential use for drug screening and therapeutic research; allows exploration of its efficacy in NUT midline carcinoma and other therapeutic approaches
Other at Georgetown UniversityFrame IPACE posted this:
Nutraceutical Beverage From Coffee CherryCoffee cherry, commonly discarded during coffee bean production, is repurposed in this innovation into a high-value nutraceutical through a clinically validated, sustainable extraction process. Rich in antioxidants and natural bioactive compounds, the product supports cardiovascular function, raises HDL (good) cholesterol, lowers LDL (bad) cholesterol and triglycerides, enhances metabolic performance, and improves blood circulation. The process is designed with minimal environmental impact generating low emissions and aligning with zero-waste, circular economy models. Backed by clinical testing for both safety and efficacy, the technology offers a scientifically grounded, health-driven alternative to synthetic supplements. The inventors seek licensing partnerships with food, beverage, and nutraceutical manufacturers, and also welcome collaboration with academic institutions for further research into coffee cherry compounds.
International Business Development Specialist at Frame IPACEHygea Salud y Nutrición posted this:
Nutritional software which makes automatically personalized diets.Vitadieta is a system of Medical Nutrition Therapy, which makes automatically personalized diets for a wide range of goals (lose weight, healthy diet, sports nutrition, pathologies...). The system could be integrate inside a third-party software, or works online. Vitadieta offers functionalities of cross-selling oriented to franchises, recomending product and services of each franchise with the diets.CSIR posted this:
Nutritious South African organic vegetable drinkAn affordable, nutritious organic vegetable drink containing indigenous South African plants. It is an instant sorghum based dry pre-mix containing milled vegetable ingredients and is available in vanilla, chocolate and strawberry flavours.
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Luxembourg Institute of Science and Technology (LIST)Luxembourg Institute of Science and Technology (LIST)Luxembourg Institute of Science and Technology (LIST)Research Institute
Luxembourg Institute of Science and Technology (LIST) posted this:
Observatory for Climate, Environment and BiodiversityThe Observatory for Climate, Environment and Biodiversity (OCEB) is a multidisciplinary team of researchers and engineers who push the state of the art in monitoring and assessing various components of the Critical Zone from the top of the trees down to the groundwater. The Critical Zone is the Earth's thin surface layer where rock, soil, water, air and living organisms interact with each other. With its cutting-edge technological infrastructures and monitoring networks, the OCEB offers a wide range of services and leverages expertise and knowledge to produce science-based evidence for supporting policy-making processes towards sustainable and informed management of natural resources.UNIVERSIDAD DE BURGOS posted this:
Obtaining amines from nitrocompounds through an effective, economical and sustainable processA research group from the University of Burgos has developed a new procedure that allows transforming nitro groups (1) to amines (2) in short times and with yields that reach 95%. The key to this transformation lies in the molybdenum catalyst used and the reducing agent.









































