Technology Offers Site map description
N
Georgetown UniversityGeorgetown UniversityGeorgetown University posted this:
Novel Treatments Targeting Drug-Resistant Prostate Cancer Cells- Novel small molecule carbazole compounds effectively inhibit androgen receptor signaling, overcoming resistance to current prostate cancer treatments. - Broad efficacy against castration-resistant and enzalutamide-resistant prostate cancer addresses critical unmet needs in advanced disease. - Potential applications extend beyond prostate cancer to other androgen receptor-positive cancers, including breast, ovarian, and fallopian tube cancers.
University of Szeged posted this:
Novel types of C-3 substituted kynurenic acid derivatives with improved neuroprotective activityNeurodegeneration may occur when the brain is exposed to high level of reactive oxygen species, mitochondrial dysfunction, neurotoxicity, such as excitotoxicity. Administering neuroprotective agents can prevent the chronic conditions damaging nerve cells. Therefore, there is an urgent need to develop effective neuroprotective agents.
Sayali WaradUniversity of Alberta, Technology Transfer ServicesSayali Warad posted this:
NOVEL VISCOELASTIC MODEL FOR ENHANCED OIL RECOVERY AND RESERVOIR SIMULATIONA predictive model for polymer behavior. It can be used for recovering oil from a depleted oil reservoir and for screening polymers. Companies using this technology will have the ability to significantly increase the accuracy of polymer screening for injectivity and oil recovery operations, as well as the accuracy of numerical reservoir simulation.
IP Market Analyst at University of Alberta, Technology Transfer Services
Universidad de AlicanteUniversidad de AlicanteUniversidad de Alicante posted this:
Novel visual inspection system for quality control in production procesessVisual inspection systems are based on the employment of pictures, both in the visible and infrared or ultraviolet spectrums. They can also make use of sonar images or adding structured light to the environment in order to analyze defects and shapes in products. The figure shows an image obtained by means of a range camera that allows distinguishing an object by its depth. Thus, its position and defects can be determined through its volume. The technology is totally developed and has been laboratory and field tested, although, it requires a particular specification for each case. The technology can be used for real-time inspection of production processes, both for the recognition and for the classification and quality inspection.
- Georgetown UniversityGeorgetown University
Georgetown University posted this:
NSG prolactin humanized mouse model to evaluate therapeutic strategies of ER+ breast cancerResearchers at Georgetown University and the University of Nebraska have developed a humanized mouse model expressing the human prolactin gene, to better study ER+ breast cancer. Current models do not properly represent the hormonal environment seen in patients. Furthermore, mouse prolactin fails to activate human prolactin receptors in xenograft experiments, ultimately selecting for prolactin-independent tumor growth and differentiation. This model overcomes these limitations by replacing the mouse prolactin gene, with a knock-in of human prolactin, therefore mimicking the hormonal environment of breast cancer patients. Crossing these mice with immunodeficient strains, allows for human cell transplantation and engraftments to reliably study ER+ breast cancer. BACKGROUND High levels of circulating prolactin have been associated with an increased risk of breast cancer. Together with ER and PR, prolactin plays a crucial role in breast development, influencing both mammary cell proliferation and differentiation. Although prolactin receptors are expressed in the majority of breast cancers, current mouse models fail to account for the hormonal environment seen in patients. In these models, human prolactin is not sufficient to activate mouse prolactin receptors, while mouse prolactin acts as an antagonist to the human prolactin receptor. The NSG-Pro mouse overcomes these issues by expressing the human prolactin gene allowing for physiological levels of circulating human prolactin, and therefore more reliable assessments of disease progression and drug response.
Innovation OfficeUniversity of GalwayInnovation OfficeAccelerates research impact, empowers start-ups and engages for innovation. at University of Galway
View ProfileInnovation Office posted this:
NucleoSeq Based Bacterial Detection: Fast, Precise, and ReliableBacterial infections remain a major global health challenge, requiring accurate and rapid diagnostic methods. Traditional detection techniques can be slow and cumbersome, often relying on lengthy culture times. Innovative approaches with high specificity and sensitivity are needed to improve detection speed and reliability. This technology addresses that need by targeting a widely conserved bacterial marker, enabling efficient and precise bacterial identification across various sectors.
Accelerates research impact, empowers start-ups and engages for innovation. at University of Galway
Meghan Meyer posted this:
NUT midline carcinoma cell lines TC797 and TC1297- NMC cell lines from the pleural fluid and bone marrow aspirate of a pediatric patient diagnosed with thymic carcinoma. - Unique karyotypic abnormality, an original viable cell line from a pediatric patient (1997). - Potential use for drug screening and therapeutic research; allows exploration of its efficacy in NUT midline carcinoma and other therapeutic approaches
Other at Georgetown University
Frame IPACEFrame IPACEFrame IPACE posted this:
Nutraceutical Beverage From Coffee CherryCoffee cherry, commonly discarded during coffee bean production, is repurposed in this innovation into a high-value nutraceutical through a clinically validated, sustainable extraction process. Rich in antioxidants and natural bioactive compounds, the product supports cardiovascular function, raises HDL (good) cholesterol, lowers LDL (bad) cholesterol and triglycerides, enhances metabolic performance, and improves blood circulation. The process is designed with minimal environmental impact generating low emissions and aligning with zero-waste, circular economy models. Backed by clinical testing for both safety and efficacy, the technology offers a scientifically grounded, health-driven alternative to synthetic supplements. The inventors seek licensing partnerships with food, beverage, and nutraceutical manufacturers, and also welcome collaboration with academic institutions for further research into coffee cherry compounds.
International Business Development Specialist at Frame IPACE
Hygea Salud y Nutrición posted this:
Nutritional software which makes automatically personalized diets.Vitadieta is a system of Medical Nutrition Therapy, which makes automatically personalized diets for a wide range of goals (lose weight, healthy diet, sports nutrition, pathologies...). The system could be integrate inside a third-party software, or works online. Vitadieta offers functionalities of cross-selling oriented to franchises, recomending product and services of each franchise with the diets.
CSIR posted this:
Nutritious South African organic vegetable drinkAn affordable, nutritious organic vegetable drink containing indigenous South African plants. It is an instant sorghum based dry pre-mix containing milled vegetable ingredients and is available in vanilla, chocolate and strawberry flavours.
O
Luxembourg Institute of Science and Technology (LIST)Luxembourg Institute of Science and Technology (LIST)Luxembourg Institute of Science and Technology (LIST)Research Institute
Luxembourg Institute of Science and Technology (LIST) posted this:
Observatory for Climate, Environment and BiodiversityThe Observatory for Climate, Environment and Biodiversity (OCEB) is a multidisciplinary team of researchers and engineers who push the state of the art in monitoring and assessing various components of the Critical Zone from the top of the trees down to the groundwater. The Critical Zone is the Earth's thin surface layer where rock, soil, water, air and living organisms interact with each other. With its cutting-edge technological infrastructures and monitoring networks, the OCEB offers a wide range of services and leverages expertise and knowledge to produce science-based evidence for supporting policy-making processes towards sustainable and informed management of natural resources.
UNIVERSIDAD DE BURGOS posted this:
Obtaining amines from nitrocompounds through an effective, economical and sustainable processA research group from the University of Burgos has developed a new procedure that allows transforming nitro groups (1) to amines (2) in short times and with yields that reach 95%. The key to this transformation lies in the molybdenum catalyst used and the reducing agent.
CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas posted this:
Obtaining of food-grade natural prebiotic oligosaccharides by enzymatic synthesis from disaccharidesCSIC has developed an enzymatic synthesis procedure of lactosil-fructosilated derivatives obtained from natural disaccharides. Lactosil-fructosilated derivatives are prebiotics potentially usable in healthy food compositions to prevent diseases of the gastrointestinal system. Looking for food or pharmaceutical companies to develop and produce the compound under patent license. An offer for Patent Licensing
- Universidad de AlicanteUniversidad de Alicante
Universidad de Alicante posted this:
Obtaining potent antioxidants from mulberry cell culturesThe Plant Proteomics and Functional Genomics group of the University of Alicante, in collaboration with the Institute of Integrative Systems Biology of the University of Valencia, has developed the technology of plant cell cultures of the genus Morus to obtain stilbenes. The innovation lies in the simultaneous use of two elicitor compounds to promote their production. With this technology, trans-resveratrol and trans-oxyresveratrol are obtained in high quantities, with the possibility of using them in the pharmaceutical, cosmetic and food industries thanks to their powerful antioxidant character. Companies interested in acquiring this technology for its commercial exploitation through patent licensing agreements are sought.
Jorian Bos posted this:
OCULAVIS - Remote Service Platform with customisable service apps, AR and AI applicationsSave time & money by solving problems remotely. Redefine the way service and maintenance is done today. With smart glasses, augmented reality and the multiple award-winning remote support solution Oculavis SHARE!
Other at EIT Digital
University of ManitobaUniversity of ManitobaUniversity of Manitoba posted this:
Odor Detection Platform - Low power, Low cost, Programmable Sensor ArrayResearchers at the University of Manitoba have developed an artificial olfactory platform that uses commercially available, silicon-based floating gate devices functionalized through selective, electrochemical polymer deposition to produce “programmable” olfactory sensor arrays.
uacoopera posted this:
Ohmic heating reactor for chemical synthesis, the method and its applicationsIn ohmic heating electrical energy is dissipated in heat with a very high efficiency (electrodes in contact with the reaction medium), resulting in fast and uniform heating and in the increase of charged species movement. As in the case of the heating with microwave radiation, electrical energy is transformed into thermal energy. However, on contrary of heating with microwave radiation (penetration depth of microwave radiation in absorbing media is limited) the penetration depth is virtually unlimited and the extent of heating is regulated only by the spatial uniformity of electrical conductivity throughout the reaction medium and the time spent in the ohmic reactor. Thus, the direct scaling of the ohmic heating for the pilot or industrial scale shouldn’t have the limitations presented by microwave radiation heating. It is also possible to reduce reaction times and increase the energy efficiency of chemical reactions- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Oleuropein obtaining procedure: high purity antioxidantCSIC has developed a reliable and effective method for obtaining oleuropein from olive leaf: comprising a pretreatment that increases the concentration of oleuropein in the extracts over other known methods and achieving this bioactive compound with a purity superior of 70%. Industrial partners from the food and pharmaceutical industry are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing
University of Porto posted this:
OLFABIONERVE - Olfatory mesenchymal stem cells for peripheral nerve regenerationThis invention provides a new therapeutic method for repair of peripheral nerves after injury using olfactory mucosa-derived mesenchymal stem cells (OM-MSCs) and their secretome. Preliminary studies on animal models indicate enhancements in motor performance and sensory functions, suggesting that this method may effectively restore nerve function. This technology is adaptable for use in both human and veterinary medicine, addressing various types of peripheral nerve injuries. Furthermore, the integration with established biomaterial technologies helps to support and direct nerve regrowth and may facilitate regulatory compliance for clinical applications.
University of Porto posted this:
Olive pomace-based hydrogels containing novel micelles with rutin and resveratrol for topical useThe incoporation of rutin and resveratrol promotes the micelles protection and facilitates their permeability into the skin, enhancing their biological action. These micelles have healing, antioxidant, and anti-aging properties due to the presence of rutin and resveratrol. The materials used are safe, green, easily found in nature and respond to the environmental concerns. The formulation of this product aims to achieve a one-step procedure to input rutin and resveratrol in the biocompatible hybrid micelles, develop a low-cost product with diverse skin benefits and develop an innovative green technology-based skin care product from natural and safe ingredients. Additionally, the NanoMICDermo addresses economic, environmental and social sustainability challenges by using food by-products (olive pomace) as a source for hydrogels.
Jorian Bos posted this:
OMNIBOT - Independent, Next Generation Conversational A.I. PlatformOmniBot’s conversational AI platform allows developers and companies to easily build advanced chatbot and voice assistant interface into any web, mobile or IoT application with maximum data privacy and security.
Other at EIT Digital
UNIVERSIDAD DE BURGOS posted this:
On Screen Interface SoftwareThis software makes the use of the computer possible to a number of disabled individuals. It shows on the computer’s screen a configurable interface where the user has access to all keyboard and mouse functionalities. It is presented as a scanner keyboard where the active key is moving through rows and columns at a configurable speed. In its journey the active key encounters the mouse functions and other useful keys as well. When the user wants to select the active key the click function has to be performed. The way it is performed is also configurable: mouse click, a specific key on the keyboard, the space bar, any key… Once the key has been selected it works as it had been press on the real keyboard or mouse and the active key keeps going to give the user access the rest of the functions on the screen on a round basis.
Yeda posted this:
On-Chip Synthetic Biology Platform for Diagnostics and TherapeuticsCell-free synthetic platforms that enable complex biological activities such as synthesis and self-assembly of biomolecules, can be employed for various applications, including drug discovery and diagnostics. Using synthetic genes, we provide a novel platform for cell-free synthetic biology on a chip which is a crucial step toward creating a self-replicating artificial cell and a general strategy for developing diverse multi-component macromolecular machines. This technology, done in a cell-free environment, has a strong potential in drug discovery and diagnostic applications.
IMDEA Energy posted this:
On-sun testing of materials, devices and equipment for concentrating solar thermal and high-temperature applicationsSolar tower facility to conduct research on concentrating solar thermal applications and technologies and materials testing under high temperature is offered. We are looking for commercial agreement with technical assistance and research cooperation agreement.
- Sayali WaradUniversity of Alberta, Technology Transfer Services
Sayali Warad posted this:
ONCOLYTIC VIRUSES AND METHODS FOR TREATING NEOPLASTIC DISORDERSA vaccinia virus vaccine (ΔF4LΔJ2R) engineered for safety and designed to replicate precisely rapidly dividing cells Bladder cancer candidate UAB-211 infects BCG-resistant cells and outperforms BCG in animal models. Animal data in a highly aggressive bladder cancer model shows a 50% long-term complete response ΔF4LΔJ2R vaccinia + radiation has shown efficacy in an animal model of glioblastoma
IP Market Analyst at University of Alberta, Technology Transfer Services
Yeda posted this:
One Step Synthesis of L-DOPACurrent synthetic pathways of the standard Parkinson’s disease treatment, L-DOPA (levodopa), are complicated, requiring multiple steps, and depend upon the use of either hazardous starting compounds or producing toxic side products. The present technology offers an alternative synthetic method that is greatly simplified for the production of LDOPA. Using only Tyrosine as a feedstock, the production of L-DOPA is efficient without the generation of side products, and ecologically friendly as no toxic starting materials or side products are used or produced.
University of Porto posted this:
One-Electrode Contactless CellsThe present invention discloses a device that consists of one-electrode cells that can be used individually or connected to form a series of two or more cells. In a device constituted by one or more ferroelectricity-induced superconductor cells, the cells do not have to be in physical contact with one another; with the spontaneous and dynamic allignment of the dipoles of the ferroelectric, a potential difference is induced in different points of the surface of the cell, cells or device and a current can be harvested by conductor-terminals.
Jordi ReverterInstitut Català de Nanociència i NanotecnologiaJordi Reverter posted this:
one-step method for the postsynthetic modification of metal-organicframeworksMetal-organic frameworks (MOFs) are among the most attractive porous materials known today. Their high surface-to-mass ratio makes them extremely useful in many processes, from gas sorption, storage and separation, to catalysis, drug delivery and heat exchange. Typically they are modified post-synthesis (PSM) to optimise their chemical functionality and/or pore surface to a specific application. We propose a new approach to PSM.
Licensing Manager at Institut Català de Nanociència i Nanotecnologia
Sección de Innovación:Valorización y EmprendimientoUniversitat de ValènciaSección de Innovación:Valorización y EmprendimientoInnovation Consultant at Universitat de València
View ProfileSección de Innovación:Valorización y Emprendimiento posted this:
One-step water recycling for inorganic and organic pollutantsResearchers from Universitat de València in collaboration with Università della Calabria have developed a new patented technology related to water recycling and Metal-Organic Frameworks. The patent application consists of new materials that eliminate inorganic and organic pollutants in a single step. In this way, these materials avoid the multi-step sequential protocols that are currently applied in water recycling plants. The materials of this invention are based on Multivariate Metal-Organic Frameworks (MTV-MOFs). They have a wide range of applications in water recycling plants such as pharmaceutical, textile, food, plastic, mining... etc, as well as for agricultural and domestic use.
Innovation Consultant at Universitat de València
