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Biomedical Research Center Sant Pau (IIB)Biomedical Research Center Sant Pau (IIB)Biomedical Research Center Sant Pau (IIB) posted this:
New protein with organ-protective properties capable of reducing the size of damaged tissue by protecting against ischemia and subsequent reperfusion of the damaged areaThe asset, identified in a double-blind experimental study of myocardial ischemic injury, is a truncated form DJ1∆12 of the DJ-1 protein (PARK7; Parkinson's disease protein 7). Experiments demonstrate the peptide’s ability to protect against organ damage caused by ischemia and subsequent reperfusion of the occluded artery.
CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas posted this:
New quinoline compounds for use in the treatment and prevention of viralinfections by virus of the family Coronaviridae CSIC has identified new quinoline derivative compounds for use in the treatment and/or prevention of viral infections by virus of the family Coronaviridae, especially by respiratory syndrome-related coronavirus such as SARS-CoV-2 and hCoV-299E. Industrial partners from the pharmaceutical industry are being sought to collaborate through a patent licence agreement and/or a co-development agreement.
UNIVERSIDAD DE BURGOS posted this:
New recycled concrete with high strength and improved shrinkageResearchers from the University of Burgos (UBU) have developed a high-performance concrete (HPC) and improved shrinkage, made with recycled concrete aggregate (RCA) and reactive magnesium oxide (MgO). The developed concrete has a high workability, which allows a simple and economical installation, and a high strength, which allows using it in any type of structural element according to the current applicable regulations. The use of magnesium oxide allows reducing shrinkage, which is very high in HPC due to its high cement content. This, in turn, reduces the cracking caused by this phenomenon and improves the durability of the structural elements.
Universidad de AlicanteUniversidad de AlicanteUniversidad de Alicante posted this:
New reusable, lightweight and economical formwork elementThe research group Materials and Construction Systems for Buildings of the University of Alicante has developed a reusable formwork element to implement joints with continuous reinforcement armours in reinforced concrete construction elements. It is easy to adapt to any construction element currently available in the market. It is a low cost element, quick and simple to use it, and it allows to obtain clean and geometric concrete joints. The research group is looking for companies interested in license agreement or other kind of cooperation.
Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC posted this:
New robust and reliable chromatic dispersion measurement systemNew chromatic dispersion measurement techniques have been developed to improve some weakness of current commercial analyzers. The technology based on detection of amplitude nulls allows a significant reduction of the cost and complexity. Partners to further develop the system and/or to establish commercial agreements with technical cooperation are sought.
Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRIUniversidad de Alcalá-OTRI posted this:
New set of software tools for the strategic planning of 2nd and 3rd generation mobile networks and its extension to networks of 4th generation LTEThe principal potential of these tools lies in the use of very advanced algorithms of planning of mobile networks that allow to optimized the network from the point of view of the investment that has to be done by the operator. The current commercial models are usually based on small programmes done in Excell that evidently does not have the optimum potential of these heuristic developed in languages of high-level programming. These tools provide the necessary information to the cost model LRIC Bottom Up defined by the European Commission. Operators and governments of different countries already have used the tools that are described in this document.- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
NEW SOLUTION TO PREVENT EXCESSIVE WEAR IN GEAR USEFUL FOR WIND TURBINESA new system to prevent the excessive wear in a tooth gear has been developed and patented. The system is specially developed to prevent the wear at the pitch and/or yaw gear tooth systems from the wind turbines but it could be used in others gears applications. Partners to further develop the system and/ or to establish commercial agreements along with technical cooperation are sought.
- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
New solution to prevent excessive wear in gear, useful for wind turbinesNew solution to prevent excessive wear in gear, useful for wind turbines.
Universidad de Cádiz posted this:
New specific and optimized culture medium based on glycerine that increases the yield of processes for producing ethanol and hydrogenExploitation of the large amounts of glycerine produced as a by-product of the production of biodiesel and similar industrial processes. The employment of this culture medium increases the production yield of ethanol and hydrogen, in comparison with that obtained from the use of other sources of carbon. The effect of optimizing the culture medium is to reduce the costs and save energy in the industrial-scale fermentation process. No other alternative culture media exist that have been formulated and optimized for E. coli that would allow greater production yields of ethanol to be obtained. It represents a simple and attractive way of producing hydrogen and ethanol from a carbon source of low price and in plentiful supply. The high degree of reduction of the glycerine, in comparison with sugars, allows reduced chemical compounds such as succinate, xylitol, propionate, hydrogen and others to be obtained.- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
New strategy for local diffusion of dopants in crystalline siliconA new methodology to replace conventional diffusion processes has been developed and patented. This simple procedure offers a wide versatility, since it allows the creation of locally doped regions without photolithography steps while simultaneously reducing the global thermal budget of the emitter creation process. The potential of the method has been already confirmed for silicon solar cell applications. Partners to further develop the technology and/or to establish commercial agreements along with technical cooperation are sought.
University of Vigo posted this:
New sustainable adsorbent for bleaching efficient industrial effluentsMany industries, such as those belonging to the textile, wine, and paper industry, consume huge volumes of water and, as a result, generate a large amount of contaminated water containing persistent colour pollutant compounds. These compounds represent an environmental and health threat due to their well-known associated problems, such as carcinogenicity, toxicity and mutagenicity. Furthermore, they entail a great environmental impact when discharged in aquatic environments, perceptible at very low concentrations, creating an undesirable visual impact, which, in many cases, does not meet the degree of conformity under the current directives on the wastewater treatment for industrial effluents (Directive 91/271 / EEC). The solution proposed by the research group Chemical Engineering at the University of Vigo, is the use as adsorbent of peat, or a similar lignocellulosic material, immobilized in calcium alginate beads. This process is efficient, cheap and environmentally friendly, unlike other processes and technologies. In fact, the utilization of peat instead of activated carbon as industrial adsorbent has the advantage that peat requires no activation, unlike activated carbon, reducing operating costs. In addition, the low cost of the adsorbent would be translated into significant economic benefits. Moreover, depending on the contaminant removed from the waste effluent, the exhausted adsorbent may be used as soil fertilizer at its end of life.UNIVERSIDAD DE BURGOS posted this:
New synthetic marine alkaloid analogs with anticancer activityCancer is one of the leading causes of death in the world. Therefore new improved chemotherapeutic agents are needed. The tambjamines are a class of marine alkaloids with intriguing pharmacological properties, including antitumor activity. Inspired in the structure of these compounds we have synthesized a family of synthetic analogs displaing interesting antitumor activity "in vitro", promoting apoptosis in several cancer cell lines.
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
New system to modulate the degree of silencing of a gene of interest in plantsCSIC and UPV have developed a system that allows modulating the degree of silencing of any gene that is of interest in plants. Until now, the technologies used to regulate gene expression in plants only allowed to induce a high degree of silencing, but the level of silencing had not been regulated. This new system, through the use of small artificial RNAs (sRNAs), modulates the degree to which gene silencing occurs. This technology has a special interest in the case of wanting to silence a lethal gene and, for example, when the gene that is silenced is regulating the flowering time. Companies interested in patent licensing are sought for the development. An offer for Patent Licensing
Universitat de LleidaUniversitat de LleidaUniversitat de Lleida posted this:
New tannin-rich extract from vegetal sources for tanning hides and skinsThe A3 Chair in Leather Innovation developed an innovative aqueous extraction procedure to obtain a tannin-rich extract from seed grapes. The new extract contains a mixture of tannins and non-tannins which confers an improved antioxidant and light fastness properties. The extract also contains a colouring agent similar to that obtained with the Chestnut Tree extract. The main characteristic is the capacity to precipitate proteins and make them resistant to decomposition, for which reason the extract is useful as tanning agent for hides and skins.
University of WaterlooUniversity of WaterlooUniversity of Waterloo posted this:
New target site to inactivate the coronavirus main protease (Mpro)Background The ongoing threat posed by coronaviruses, including SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) that caused the recent COVID-19 pandemic, as well as past outbreaks such as SARS-CoV and MERS-CoV, have underscored the critical need for effective therapeutics. The evolving nature of these viruses, along with concerns about future outbreaks at regular intervals and the imperative to safeguard vulnerable populations globally have driven ongoing research and investment for the therapeutics market. The COVID-19 pandemic caused by SARS-CoV-2 has led to a global health crisis, with evolving variants reducing the efficacy of existing vaccines. Recognizing the threat posed by various coronaviruses, there is an urgent need to develop antiviral drugs against a variety of coronaviruses. Central to this effort is targeting the viral main protease, Mpro, which plays an essential role in viral replication by processing polyproteins into their functional components. Thus, Mpro emerges as a promising target for the design and development of effective antiviral drugs.
- Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRI
Universidad de Alcalá-OTRI posted this:
New technology for Air Traffic Management.A research group from a Spaniard university has designed a new system based on optimal control technology for Air Traffic Management (ATM). The new approach is mainly characterized by its adaptability capacity in situations where there are more than two aircrafts. Potential collaborations with international/national research centres and companies interested in applying the technology are sought. - Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRI
Universidad de Alcalá-OTRI posted this:
New technology for generating 4D-trajectories in aircrafts using dynamics and location information.A research group from a Spanish University has designed and implemented a new system based on a technology able to perform optimal navigation planning in aircrafts. The new approach is mainly characterized by its autonomously learning capacity and adaptability to changes in the dynamics of the platform and environment. Potential collaborations with international/national research centres and companies interested in applying the technology are sought. 
UNIVERSIDAD DE BURGOSUNIVERSIDAD DE BURGOSUNIVERSIDAD DE BURGOS posted this:
New test for components subjected to high pressure (up to 6000 bar)Test for components subjected to high pressure (pipes and driving elements) (up to 6000 bar) which allows: 1. To assess structural integrity and failure analysis. 2. To reproduce the work cycle (0-6000bar-0). 3. To know the performance of new components subjected to high pressure. 4. To determine the fatigue of the real component under the working pressure. 5. To perform hydraulic fracture and fatigue tests up to 6 000 bars.
UNIVERSIDAD DE BURGOS posted this:
New test for components subjected to high pressure (up to 6000 bar)Test for components subjected to high pressure (pipes and driving elements) (up to 6000 bar) which allows: 1. To assess structural integrity and failure analysis. 2. To reproduce the work cycle (0-6000bar-0). 3. To know the performance of new components subjected to high pressure. 4. To determine the fatigue of the real component under the working pressure. 5. To perform hydraulic fracture and fatigue tests up to 6 000 bars.
- Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRI
Universidad de Alcalá-OTRI posted this:
New therapeutic agents for the treatment of inflammatory disordersThe research group, « Heterobetaines », from Alcalá University in colaboration with the research group « Hipersensibility to medicines and inmmunitary innate response » form IDI La Paz, present a new generation of inhibitors of alfa tumoral necrosis factor (TNF-α) production, useful to prevent and / or treat inflamatory diseases. The group is looking for technical cooperation or license agreements with pharmaceutical companies, research centers or diagnostic and treatment against inflammatory diseases research institutions.
- Universitat de LleidaUniversitat de Lleida
Universitat de Lleida posted this:
New therapeutic candidate for Spinal Muscular AtrophyDevelopment of a therapeutic solution for Spinal Muscular Atrophy (SMA) focused to restore protein SMN levels in neurodegenerative disorder which primarily affecting motor neurons (MNs). Spinal Muscular Atrophy (SMA) is a genetic neuromuscular disease characterized by muscle atrophy and weakness. The disease generally manifests early in life and is the leading genetic cause of death in infants and toddlers. SMA is caused by defects in the Survival Motor Neuron 1 (SMN1) gene that encodes the SMN protein. The SMN protein is critical to the health and survival of the nerve cells in the spinal cord responsible for muscle contraction (motor neurons).
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
New therapeutic cannabidiol derivativesNew therapeutic cannabidiol derivatives CSIC, Temple University, and the University of North Carolina Greensboro have developed pyrazolylbenzene-1,3-diols for diseases associated with G protein-coupled receptor 18 (GPR18) and in combination with transient receptor potential vanilloid 1 (TRPV1) potentially useful against a wide range of disorders. Industrial partners from the biotech or pharmaceutical industry are being sought to collaborate through joint development and patent license agreement. An offer for Patent Licensing
OTRI-Universidad de MálagaUniversidad de MálagaOTRI-Universidad de Málaga posted this:
NEW THERAPEUTIC TARGET IN THE TREATMENT OF ALZHEIMERA study carried out through the use of systems biology, with the analysis of complex data, starting with omics data and using integrative tools for the analysis of dynamic and modular responses, has identified a candidate target and the use of its inhibitor as new useful drug to combat Alzheimer's disease. The present invention refers to the total or partial inhibition of the expression of the localized gene, or of the activity of the enzyme encoded by said gene, to be used for the treatment of Alzheimer's disease.
Technology Transfer Office (TTO) at Universidad de Málaga
Universidade de Santiago de CompostelaUniversidade de Santiago de CompostelaUniversidade de Santiago de CompostelaTechnology Transfer Office
Universidade de Santiago de Compostela posted this:
New Thermal Sensing for Microcalorimetry and Microfluidics (ERC-PoC project)The prototype developed within ERC-PoC "ANTS" project, has demonstrated its sensitivity for a new concept of microcalorimeters, as well as providing advantages in microfluidics. We aim to: a) Integrate this technology within microfluidic devices or applications where size and fast response time are crucial. b) Develop a High-Throughput Calorimetry going beyond the current capabilities on ITC. > Sensing element. Ferromagnetic permalloy line 4x28 µm x 20 nm thick: affordable, miniaturization… Sensor was fabricated in a single deposition. > Temporal response. Milliseconds, to stimulus >10 microwatts; further improvements are in progress. > Easy adoption. Compatible with standard configuration of microcalorimeters. > IPR: EP, US, CN, KR, JP
CNIC (TTO)Spanish National Center for Cardiovascular Research (CNIC)CNIC (TTO)Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)
View ProfileCNIC (TTO) posted this:
New tools to improve the diagnosis and treatment of early atherosclerosisCardiovascular diseases (CVDs) are the leading cause of death worldwide, with atherosclerosis (AT) being its main determinant. Currently, AT prevention is based on traditional scores that, however, fail to identify individuals at risk at early stages. The exact prevalence of subclinical atherosclerosis is impossible to determine, although it has been estimated in the USA that 50% of men and 64% of women who died of sudden cardiac death did not have a previous manifestation of the disease and most of them were not considered high risk according to the Framingham score. Subjects that suffer from CV events despite pharmacotherapy or those that are intolerant to it, emphasize the need for alternative treatments to be explored. CNIC researchers have discovered a metabolite as biomarker to identify individuals at risk at early stages, and the use of antagonist to this metabolite as new tool to improve the treatment of early AT. This treatment will be effective not only for AT, but also for autoinflammatory diseases.
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
New treatment for epidermolysis bullosa and fibrosisCSIC, Carlos III University of Madrid and CIEMAT have repositioned drugs that stimulate endogline expression and modulate the TGF-β route for a new clinical use in the treatment of fibrosis, such as epidermolysis bullosa (EB). EB includes a heterogeneous group of rare hereditary diseases of the skin in which in its infantile incidence the patients are known as "butterfly children". It is a new therapy for a rare pathology, with potential in a wide spectrum of fibrosis, which would improve the possibilities of treatment of patients, improving their quality of life. Industrial partners from the pharmaceutical industry are being sought for its development in a wide variety of fibrotic pathologies through a patent licence agreement. An offer for Patent Licensing
IBIMA-Plataforma BionandIBIMA-Plataforma Bionand
Covid-19 Innovation Challenges by InnogetCovid-19 Innovation Challenges by InnogetCovid-19 Innovation Challenges by Innoget posted this:
New use for an existing drug as antiviral agent against SARS-CoV-2 to prevent or/and treat COVID-19CSIC has discovered a new use for an existing drug on the market as antiviral agent. Industrial partners from the pharmaceutical industry are being sought to collaborate through a patent licence agreement.
Marta García Del BarrioConsejo Superior de Investigaciones Cientificas (CSIC)Marta García Del BarrioCommercialization Specialist at Consejo Superior de Investigaciones Cientificas (CSIC)
View ProfileMarta García Del Barrio posted this:
New use for an existing drug as antiviral agent against SARS-CoV-2 to prevent or/and treat COVID-19CSIC has discovered a new use for an existing drug on the market as antiviral agent. Industrial partners from the pharmaceutical industry are being sought to collaborate through a patent licence agreement.
Commercialization Specialist at Consejo Superior de Investigaciones Cientificas (CSIC)
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
New use of cabergoline in breast cancer chemopreventionNew use of cabergoline in breast cancer chemoprevention A CSIC research group have found that Cabergoline exerts an increased latency and decreased breast cancer incidence in a mouse model deficient in Brca1/P53. An only single dose is needed to potentiate post-lactational gland involution and a decreasing of epithelial proliferation, providing less tumor susceptibility in mice. Results suggest Cabergoline could be a strong and safe protective drug for breast cancer prevention. It could be administered after breastfeeding to enhance the protective effect of pregnancy against breast cancer or later, to reduce the risk of post-pregnancy breast cancer in women over 30-35 years old. Pharmaceutical company is sough for further licensing. An offer for Patent Licensing
