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Larisa SheloukhovaKyoto UniversityLarisa Sheloukhova posted this:
Optimization of precise gene editing in human iPS cellsThe discovery of CRISPR-Cas system for genome editing has revolutionized experimental biology. Research labs all over the world are using multiple variations of the system to answer fundamental questions in genetics, model diseases, and develop therapies. However, precise gene editing to generate single-nucleotide modifications needed for accurate disease modeling and therapeutic development has seen limited success. The Woltjen Lab has developed methods to optimize precise gene editing in iPS cells by combining a series of techniques using CRISPR-Cas9.
Global Tech Commercialization at Kyoto University
Unismart - University of Padua FoundationUnismart - University of Padua FoundationUnismart - University of Padua Foundation posted this:
Optimized analysis of slurry in agricultureThis patented system uses data fusion techniques in order to obtain accurate data of the chemical composition of these byproducts, which are potentially pollutant. The use of slurry from animal farming or anaerobic digestion for fertilization is beneficial for the economy of animal or biogas farms but may cause the pollution of ground or surface water if distribution is done incorrectly.
CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas posted this:
OPTOBIOTICS: Novel antibacterial proteins activated by blue lightCSIC has developed a chimeric protein that, when expressed in bacteria, changes its structure upon absorption of blue light, thus generating protein aggregates (amyloids) that inhibit bacterial growth Industrial partners from the pharmaceutical industry are being sought to collaborate through a patent licence agreement An offer for Patent Licensing
RAMOT at Tel Aviv University Ltd.RAMOT at Tel Aviv University Ltd.RAMOT at Tel Aviv University Ltd. posted this:
Oral Mucosa-derived Stem Cells: A Unique Population for the Prevention and Treatment of Ischemic Heart FailureStem cells (SC) are considered crucial building blocks for any regenerative strategy. Adult oral mucosa (OM) is a unique source for generating adult pluripotent stem cell (OPSC) populations. This uniqueness consists in the fact that 95% of the OM whole populations in culture (1st – 8th passages) express markers of embryonic and mesenchymal SC. Thus, in contradistinction to known sources which comprise very low numbers of SC, OPSC generation for clinical use is simple and cost effective and does not require cumbersome cost-consuming purification steps. The general objective is to lay the foundation for the development of a variety of products based on the pluripotency and simple and cost effective generation of billions of OPSC. The major aim of the proposed project is to develop a product for the treatment of ischemic heart failure (IHF). This product which will serve as a proof of concept was selected based on medicals needs, market cap and time to market. The specific aims of the proposal are: 1. To develop a cardiac product aimed at treating ischemic heart failure (IHF). The aim is to test the safety and therapeutic effect of OPSC on experimental IHF in a minipig model. 2. To strengthen the intellectual property by fully characterizing the profile of OPSC. The prevalence of IHF continuously increases (1 million new cases every year in the western world) and currently the market cap is estimated in the range of billions. Project ID : 10-2011-260
Nerea AlonsoFundación Biomedica Galicia SurNerea Alonso posted this:
ORAL STREPTOCOCCI WITH BACTERICIDAL ACTIVITYUse of a new species of streptococcus, Streptococcus downii, and/or bioactive compounds derived from it for the treatment of infections of the oral cavity, such as caries and periodontitis. S. downii belongs to the group of healthy commensal oral streptococci.
Innovation Manager at Fundación Biomedica Galicia Sur- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Organic derivatives for the manufacture of electronic devicesCSIC have developed organic derivatives, low cost, with possibility of modifying its molecular structure, including different substitutions, improving the properties of electronic semiconductor. These molecules present not only interesting electronic properties which make them active for the manufacture of solar cells, specifically organic photovoltaic cells, but also an intense blue color which allows it so be used as a dye in the textile industry. Industrial partners from the energy, electronic and textile are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing UNIVERSIDAD DE BURGOS posted this:
Organic molecule capable of detecting explosivesResearchers from the University of Burgos have designed a method to synthesize a compound that is extremely useful in the detection of explosives, such as triacetone triperoxide. This explosive is very simple to prepare and extremely difficult to detect. The project has been subsidized by NATO and, given the potential of the molecule, a patent has been applied for to protect and commercialize it.
UNIVERSIDAD DE BURGOS posted this:
Orientation of fibers within composites: improvement of material properties and manufacturing processIt is well known that there are correlations between fiber orientation and mechanical and/or physical properties of the composite. Knowing the real orientation of the fibers within a composite material can help to optimize the design and manufacturing process. A composite material contains materials of different densities (fibrous material and matrix), and these have different X-rays absorption capacity, generating different grey levels in scanned images. This allows later identification and separation by the computed tomography scan (CT-scan), a non-destructive technique that provides scanned images with the orientations of fibrous or filamentary components contained inside a composite material, and therefore its mechanical and/or physical properties. However the interpretation of these images depends on the criterium of the technicians, being a subjective opinion. This subjective interpretation can be solved by our computer implemented method that allows a numeric objective valoration of the orientations of fibres or filaments inside the composite. The final result is a more efficient use of the fiber, and therefore an optimal design, from both structural and economical points of views.
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Overcoming resistance to Beta-lactam antibiotics in Bacterial speciesCSIC and the University of Würzburg have developed a new method to eliminate antibiotic-resistant bacterial infections using classical antibiotics previously discarded due the occurrence of antibiotic resistance. Industrial partners from the pharmaceutical industry are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing
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University of WaterlooUniversity of WaterlooUniversity of Waterloo posted this:
P2K: Pattern to knowledge AI software for predicting residue interacting sites between proteinsBackground Relations and functions in living systems are complex and entwining due to intertwining unknown factors of subjects and environment. Currently, protein binding predictions are based on residue-residue close contact (R2R-C) data procured from existing 3-dimensional protein-protein interaction complexes (Fig.1). However, numerous physio-chemical/stereo factors in the complex interacting environment might affect R2R-C (Fig.2). R2R-C association patterns could be masked at the data level and misleading, yielding unreliable Residue to Residue Interaction (R2R-I) predictions. Therefore, new methods capable of discovering and disentangling R2R-I patterns are needed to enhance the understanding and prediction of protein-to-protein interactions with reasons rather than just giving a black-box decision.
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Paper-based temperature sensor with high sensitivityThe CSIC has developed a thermo-resistive sensor comprising a semiconductor material onto a paper substrate. The use of this type of materials together with deposition technique of semiconductor element allow to design a thermo-resistive sensor with high sensitivity to abrupt temperature changes being up to an order of magnitude more sensitive than analogous sensors based on graphite. The use of paper as substrate makes this sensor cheap, easy to produce and biodegradable. The incorporation of this device in fabrics allows to monitor body temperature. Likewise, when integrated in packaging, it allows to record thermal history of goods. Industrial partners from the electronic components and sensors sectors or companies from textile and paper industry are being sought to collaborate through a patent license agreement.
Srusht Dastan posted this:
ParametricAI: A predictive analytics softwareBackground The global predictive analytics market is rapidly growing at a compound annual growth rate of 24.5% and is expected to reach USD $21.5 billion by 2025. Companies across all industries and particularly, the fin-tech industry are investing in this technology to mine their transactional databases to gain better customer insight, forecast sales more accurately and improve their market competitiveness. The insurance industry is in most need of predictive analytics as its business model heavily relies on effective forecasting. Predictive analytics empowers insurers to deliver exactly the right product, at the optimal cost, to the right customer, at the right time and through the right channel. Predictive analytics can flag anomalous consumer behaviour and protect against insurance fraudulent which cost at least $80 billion in fraudulent losses each year in America.
Tech Transfer at University of Waterloo
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Particle identification using a high precision system based on multi-frequency measurements of resonant platesCSIC has developed a new system that allows to identify and classify nanometric and micrometric particles. This system is based on the changes produced at different resonance frequencies of thin plate type structures when these particles are adsorbed onto their surface. This technology represents an important achievement in the field of nanomechanical spectrometry and is suitable for the identification and classification of viruses, bacteria or proteins. Industrial partners manufacturers of lab equipment are being sought to collaborate through a patent license agreement. An offer for Patent Licensing
University of Alberta, Technology Transfer ServicesUniversity of Alberta, Technology Transfer ServicesUniversity of Alberta, Technology Transfer Services posted this:
Partnering Opportunity: Effervescent Powders for InhalationUniversity of Alberta and Alberta Health Services researchers have jointly developed a new type of dry-powder inhalable carrier particle with an active release mechanism to disperse therapeutics more effectively. Most advanced product candidate based on this delivery system is an inhalable effervescent doxorubicin nanoparticle formulation; it demonstrated significantly improved survival time in a small cell lung cancer mouse model.
Universitat de València posted this:
Passive sampler for monitoring atmospheric pollutants (VERAM)The most remarkable advantages provided by this technology are: o Versatility, it is possible to sample a big number of pollutants using a single device containing a combination of solid phases. o Greater adsorption capacity and high analytic sensitivity with smaller sampling time than market available devices. o Rapidity and low cost of pollutant analysis. Thermal desorption and head space injection minimize sample handling, do not require the use of solvents and reduce the time of analysis. o Cheap passive samplers with a fast and simple fabrication procedure. o VERAM permits a multidirectional sampling differing from radial or one-way sampling devices with encapsulated solid phases.Universitat de València posted this:
Passive sensor for in situ detection of amines in atmospheres Simplicity and ease of use: it is a passive colorimetric sensor that does not require any kind of pretreatment or power supply or external instrument. Low cost: simple fabrication process without high costs Low detection limits: suitable for use in real atmospheres, of the order of 3 mg/m3. Quantitative detection: direct quantitative detection can be carried out by diffuse reflectance of the sensors. Stability: against a wide range of temperatures and to humidity and solar radiation. Reversion resistance.
Maria João CardosoInstituto de TelecomunicaçõesMaria João CardosoIntellectual Property and Technology Manager at Instituto de Telecomunicações
View ProfileMaria João Cardoso posted this:
Passive sensor system powered by wireless power transmissionNetwork of wireless and passive sensors (without batteries), using a set of unique sensors which use a frequency for the data transfer (obtained by sensors) and another frequency for the reception of energy that is emitted by transmitters that power the sensors. For this, only a central data reception and wireless transmission structure is required which communicates with each of the sensors independently. These sensors have low power consumption and high data rates (up to 960 Mb/s).
Intellectual Property and Technology Manager at Instituto de Telecomunicações
UACOOPERA University of AveirouacooperaUACOOPERA University of Aveiro posted this:
Passive sensor system powered by wireless power transmissionNetwork of wireless and passive sensors (without batteries), using a set of unique sensors which use a frequency for the data transfer (obtained by sensors) and another frequency for the reception of energy that is emitted by transmitters that power the sensors. For this, only a central data reception and wireless transmission structure is required which communicates with each of the sensors independently. These sensors have lower power consumption and higher data rates (up to 960 Mb/s).
Technology Transfer Office at uacoopera
Sura ChitrabhanuKemyas Security SystemsSura Chitrabhanu posted this:
Patented multipurpose technology for lease/joint ventureWe've developed a patented and innovative solution to detecting and controlling liquid-levels which is cost-effective and easily applicable to a wide-variety of operating scenarios and industries, such as huge storage towers, boiler drums, and sumps. The solution consists of a canister device with sensors for giving level feedback to instruments detecting the quantity of liquid in any kind of storage unit and triggering other actions. It's a versatile product that can be used in multiple operating scenarios such as dry-run protection, extraction of liquids from low-yield wells, highly corrosive substances/environments, etc. We're seeking investors and/or interested parties who would like to deploy our low-cost devices in their factories.
Inventor at Kemyas Security Systems
Universidad de La Laguna -OTRI-Universidad de La LagunaUniversidad de La Laguna -OTRI-Research Results Transfer Office at Universidad de La Laguna
View ProfileUniversidad de La Laguna -OTRI- posted this:
Pathogen capture and inactivation deviceThe invention discloses a system that permits the uptake and inactivation of pathogenic biological agents in fluids (gases or liquids) by passing the same through one or more modulable and configurable treatment zones. The combination of the different types of zones, steps and stages, allow the device to be adapted for functions such as the capture of substances or organisms, inactivation of pathogens, capture and inactivation of chemicals, additivation, humidification, as well as other processes that require the passage of a fluid through different treatment elements. The system can be used as a test device to study the capacity of different physical and chemical treatments, as well as to analyze the times and contact surfaces required to capture and inactivate pathogenic biological agents in a continuous flow of gases or liquids; serving as a tool for its own definition and final consolidation according to each case. The system, in one of its simplest configurations, is capable of inactivating microorganisms in an air flow with an efficiency of 99.99%, including SARS-Cov-2. In the event of the emergence of new pathogens in the future, the device facilitates its own redefinition for the deactivation of such agents.
Research Results Transfer Office at Universidad de La Laguna
Universidad de La Laguna posted this:
Pathogen Capture and Inactivation SystemThe proposed invention discloses a system that allows the capture and inactivation of pathogenic biological agents in fluids (gases or liquids) by passing the same through one or more modulable and configurable treatment zones. The combination of the different types of zones, steps and stages, allow the device to be adapted for functions such as the capture of substances or organisms, inactivation of pathogenic agents, capture and inactivation of chemical substances, additivation, humidification, as well as other processes that require the passage of a fluid through different treatment elements.- University of WaterlooUniversity of Waterloo
University of Waterloo posted this:
Pattern Discovery and Disentanglement (PDD) AI software for deep knowledge discovery from relational dataBackground Identifying, categorizing and explaining patterns in relational date sets is complex due to a wide range of interrelated and intertwining factors. Thus functional associations are often masked at the data level due to such hidden entanglement. This is a specific problem related to relational data sets in many areas including healthcare, finance and cybersecurity. There is a need to both discover and disentangle patterns inherent in relational data sets in order to surface deeper actionable knowledge in a way that is explainable (i.e. mitigate the AI “black box” confidence issue).
- UACOOPERA University of Aveirouacoopera
UACOOPERA University of Aveiro posted this:
Patterned surfaces for physical entrapment of drug particlesEasy-to-apply device composed of a transdermal patch with microsize patterns such as micropillars, able to efficiently entrap the maximum amount of drug particles at the microscale and release them in a controlled and sustained manner. The maximum amount of entrapped drug microparticles is enabled by the similarity between the micropillars spacing in the patch and the microparticles diameter, enhancing the dose of the therapeutic compound administrated, decreasing the need of frequently replacing the patch.
Technology Transfer Office at uacoopera
UNIVERSIDAD DE BURGOS posted this:
PAVEL: Vehicle route planning and logistics operationsSoftware developed for route optimization as intended for companies or entities interested in solving their problems of transportation planning (delivery to customers or delegations, collection suppliers, etc.). The aim of using this system is to help obtain cheaper solutions, more convenient, secure and balanced routes (according to the goals considered) and conform to the restrictions of each situation.
Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC posted this:
PC-ProTec / A novel, highly effective zinc free anticorrosive additive easily dispersible in priming paintsA novel, highly effective zinc free anticorrosive additive easily dispersible in priming paints
- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
PC-ProTec A novel, highly effective zinc free anticorrosive additive easily dispersible in priming paintsPC-ProTec is a new technology uniquely positioned as a safer alternative to replace toxic anticorrosive additives, mainly zinc and its compounds, typically used in paint formulations to protect metal structures. The novel zinc-free anticorrosive pigment, which is applied in very low concentrations (0.3-1.5 wt %), is based on poly(alkyl thiophene acetate)s. This technology meets the new environmental regulations that restrict the use of zinc. Partners to further develop the technology and/or to establish commercial agreements along with technical cooperation are sought.
- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
Pc-protec additiveA novel, highly effective zinc free anticorrosive additive easily dispersible in priming paints
