Technology Offers Site map description
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Georgetown UniversityGeorgetown UniversityGeorgetown University posted this:
Improved Method for Quantifying Fucosylated GlycoproteinsThis invention provides a sensitive and specific LC-MS-MRM method for quantifying outer-arm and core fucosylated N-glycopeptides directly in plasma or serum without sample fractionation or enrichment. It utilizes optimized low-energy fragmentation to produce linkage-specific Y-ions as MRM transitions, enabling quantification of fucosylation types across multiple glycoforms of plasma proteins. The method demonstrates increased outer-arm fucosylation in liver cirrhosis patients compared to healthy controls.
Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRIUniversidad de Alcalá-OTRI posted this:
Improved procedure to obtain active principles in Aloe leavesA technology based firm, set up by researchers of Alcalá University, has developed a procedure to obtain active principles from Aloe leaves. With this procedure, a product with pharmacological, cosmetic and nutritional use is obtained. The resultant product could have therapeutic and/or food properties. Toxic compounds as phenols are removed. The researchers are interested in join venture and/or manufacture agreements.- Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRI
Universidad de Alcalá-OTRI posted this:
Improved process for selective oxidation of sulfide groups to sulfone by silsesquioxane catalysts.A Spanish-Portuguese research group from the department of Inorganic Chemistry at Alcalá University and ITQB-Universidad Nova of Lisboa of Oeiras, has developed a process of synthesis of titanium silesquioxane compounds and its applications in oxidation catalyst of organic sulphur compounds. The group looks for licencing agreements and commercial or collaboration agreements with pharmaceutical and petrochemical industry, and those industries in charge of the fertilizer preparation and production of compounds for the treatment of environmental problems.
Unismart - University of Padua FoundationUnismart - University of Padua FoundationUnismart - University of Padua Foundation posted this:
Improved solar panel recyclingThis patent improves the current methods available to separate the glass from the photovoltaic cells. This patent has developed a simple and effective method to improve the separation of the glass from the cells. Thanks to the accurate separation of each material, their value as a reusable raw material is greatly increased.
Yeda posted this:
Improved Treatment for GlaucomaGlaucoma is one of the leading causes of irreversible blindness worldwide, affecting over 60 million people. It is usually caused due to raised intraocular pressure (IOP). Although several drug classes which lower IOP are available, they all cause local and systemic side effects, and improved treatments are greatly needed. The group of Prof. Steve Karlish developed new drugs derived from Digoxin, which selectively inhibit Na-K-ATPase, an ion pump that produces the eye fluids. These compounds effectively reduce ocular hypertension in various glaucoma animal models, and as such, offer a potential new therapeutic class for IOP-lowering medications.
Tech Line Coatings, Inc posted this:
Improvement in Anodizing Type II and Type IIIA new and non hazardous additive that improves the wear resistance and corrosion resistance of anodized components. Reduces the pore structure and allows a thinner anodic layer while producing with superior characteristics. An example of corrosion improvement is in 2024 aluminum where a .001" thick layer passed 336 hour salt spray with no problem and a .006" layer with no seal coat exceeded 200 hours in Type II anodizing. Parts in salt spray won 6061 have been in salt spray since Dec 2009 with no corrosion and wear in type 2 is equal or superior to Hard CoatUniversity of Luxembourg posted this:
Improvement of power quality in electrical smart gridsThe invention provides an algorithm to optimize the quality grid by compensating the effect of disturbances in terms of voltage harmonics and distortion power. The technology is based on the use of inverter-fed power devices with modern high-speed micro-controllers and an intelligent management of the different powers to be generated. The compensation can be implemented on a self-sufficient single voltage generating power source running in stand-alone or grid-tied. It can also be shared and distributed on multiple voltage source inverters (VSI) of different powers connected on a utility grid.
CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas posted this:
Improvement of the signal / noise ratio in detectors used in hadronic therapyCSIC and the University of Valencia have developed a device that makes it possible to effectively determine the place where radiation is deposited in hadronic therapy, a decisive aspect of the clinical application of this technique against tumors. Unlike conventional radiation therapy, hadronic therapy uses heavy charged particles to irradiate the tumor. Since heavy particles destroy the tumor more effectively than photons, and it is possible to deposit a lower dose in healthy tissue. In order to use hadronic therapy, it is essential to determine in real time whether the radiation dose is being used at the intended site, and by means of this invention it is possible to monitor the radiation dose of hadronic therapy. Industrial partners whose field of application is the development of medical devices used in hadronic therapy are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing
- Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRI
Universidad de Alcalá-OTRI posted this:
Improvement of the working environment and the increase of productivity: diagnosis and solutions to improve the conciliation of work and family life for employees.A research group from the Department of Applied Economics at the University of Alcalá offers a consulting service for diagnosis and solutions to improve the work and family life conciliation for employees. The group is open to reach commercial agreements with companies that want to improve the working environment within their organization for better efficiency and profit maximization. Aware that conciliation is a matter of all, there is a need for men and women to share responsibility of their personal and professional duties. But of course, it is also fundamental a social consciousness aware of the relationship between conciliation and efficiency and better business performance, so that the investment in conciliation policies presume an improvement of business efficiency and loyalty of employees in the companies that follow these practices 
Maria João CardosoInstituto de TelecomunicaçõesMaria João CardosoIntellectual Property and Technology Manager at Instituto de Telecomunicações
View ProfileMaria João Cardoso posted this:
Improving outdoor positioning in mobile devices using anomalies in the Earth magnetic fieldOutdoor localisation system based on magnetic landmarks – magnetic anomalies that distort the expected geomagnetic field due to strong local magnetic fields, oftentimes originated by fixed man-made structures. This technology proposes to leverage those landmarks as signatures for localisation purposes.
Intellectual Property and Technology Manager at Instituto de Telecomunicações
Radoslaw Rudz posted this:
Improving stem cell culture using carnivorous plantsMesenchymal Stem Cells (MSCs) are multipotent precursor cells with the unique capacity to self-renew, proliferation and transformation into specialized cells present in many body tissues, such as muscle, adipose tissue, fibroblasts, cartilage, tendons, and nervous tissue. They are also characterized by the ability to affect the immune system by secretion of compounds that support the immune response directed among others against bacteria and parasites. They have properties enabling the secretion of chemical compounds that stimulate the formation of new blood vessels. All these attributes make them applicable in regenerative medicine, transplantology and in the treatment of many diseases. The umbilical cord blood and Wharton’s jelly MSCs are the sources from which MSCs are obtained. Due to the small amount of MSCs in the starting material, it is necessary to lead in vitro cultures to obtain sufficient numbers of cells that can be administered to the patient. Methods of isolation and culture of mesenchymal stem cells, including the growth medium, play a crucial role in obtaining the appropriate biological material that guarantees therapeutic success. Therefore, continuous improvement of procedures for isolating and in vitro culturing of MSCs is extremely important. The subject of the offer is a method of culturing mesenchymal stem cells using secretions from carnivorous plants, which increase cell adherence and proliferation, counteract their transformation into specialized cells, therefore, they longer maintain their pluripotency.
Other at Jagiellonian University
Mitsu YamamotoJapan Technology Group, Inc.Mitsu Yamamoto posted this:
In silico platform for targeting protein-protein interaction, pharmacogenomics “COSMOS”The COSMOS method developed by the research team at the Tokyo University of Science (TUS) offers a platform for “personalized drug discovery” based on a novel drug discovery methodology. The concept is to identify an optimal binding peptide that interacts with the active/regulatory site (Hot Spot) of the target drug discovery protein by using in silico methods.
Business Development Manager at Japan Technology Group, Inc.
Radoslaw Rudz posted this:
In vitro culture medium for cells, tissues, and organs of amphibiansThe subject of the offer is a specialized medium for the in vitro culture of cells, tissues, and organs of amphibians. Thanks to the unique composition of active substances and refined their concentrations to the requirements of amphibian cells, the use of medium enables long-term culture as well as a high level of cell proliferation and reduction of cell mortality.
Other at Jagiellonian University
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
In vitro method for designing a customized therapy for a subject with Parkinson´sDisease CSIC, Université de Lille, INSERM and Centre Hospitalier Regional Universitaire de Lille have developed an in vitro method for designing a customized therapy for a Parkinson ‘s Disease patient through the determination of the presence of a centrosomal deficit from that subject and therefore susceptible to receive a therapy based on a LRRK2 inhibitor. LRRK2 is a key player for the development of both genetic and sporadic forms of Parkinson’s Disease (PD). Industrial partners from pharmaceutical industry are being sought to collaborate through a patent licence agreement.
Fundación Instituto de Investigación Sanitaria de Santiago de Compostela (FIDIS)Fundación Instituto de Investigación Sanitaria de Santiago de Compostela (FIDIS)Fundación Instituto de Investigación Sanitaria de Santiago de Compostela (FIDIS)Technology Transfer Office
View ProfileFundación Instituto de Investigación Sanitaria de Santiago de Compostela (FIDIS) posted this:
In vitro method for detecting tumor growth and diagnosing or prognosticating the risk of metastasis in a human subject that has been diagnosed with uveal melanomaProblem to solve: Uveal ocular melanoma is the most common primary ocular malignancy in adults, with an incidence of approximately 7 cases per million inhabitants per year. Its incidence is therefore not very high, but it is a disease for which there are has been no alternative for more than 50 years. In addition, the American Cancer Society has published an increase in the incidence, having been diagnosed only in the United States 2,730 new cases in 2014. By the year 2018 there are anticipated 3,540 new cases in the USA. According to www.cancer.gov, the database of the National Cancer Institute of the USA, the age-adjusted average incidence of uveal melanoma in the United States is about 4.3 new cases per million inhabitants, without a clear variation related to latitude. Men have a higher incidence than women (4.9 vs. 3.7 per million). The age-adjusted incidence of this cancer has remained stable since at least the first years of the 1970s. Incidence rates in the United States are low compared with the rates of other reporting countries, which range from 5.3 to 10.9 cases per million. Part of the variation may be the result of differences in the inclusion criteria and calculation methods. Innovation: The present invention provides an in vitro method for detecting tumor growth and diagnosing or prognosticating the risk of metastasis in a human subject that has been diagnosed with uveal melanoma, wherein the biological sample is treated with a lysis agent capable of disrupting the membrane of the exosomes prior to determining the expression of the melanocyte protein PMEL/ME20-S/gp 100. This method incorporates new techniques that differentiate it from the potential competitors in several aspects. Our method is non-invasive (as it does not require a tumor biopsy), it does not require specific training and sampling is included in the hospital routine (blood extraction). Besides, it can be used after the application of the treatment, allowing not only to monitor the tumor advance and the early development of metastasis but also to help monitoring the effect of the treatment. In addition, it would be a more economical method.
Universidad de Granada posted this:
In vitro method for the diagnosis and/or prognosis of malignant melanomaA group of single nucleotide polymorphisms (SNPs) related to the risk and aggressiveness of malignant melanoma has been identified. Thus, an in vitro method based on these biomarkers identification is proposed for diagnosis and/or prognosis of malignant melanoma and, additionally, to determine whether these patients respond adequately to treatment. In the same way, it has been proved with in vitro and in silico expression assays that the proposed SNPs for risk and aggressiveness of malignant melanoma are reinforced.
CINBIO posted this:
In vitro method for the diagnosis or prognosis of neurodegenerative disordersThe diverse etiopathogenesis and the absence of biomarkers that can be used in the diagnosis of neurodegenerative and neurological diseases make difficult a correct diagnosis and treatment. Achieving a biomarker that helps to make the correct diagnosis and select the appropriate treatment for each patient in the less possible time is crucial for the patient’s complete recovery. The present invention is focused on the provision of a panel of biomarkers elected among LRP proteins of fragments thereof. It is proposed an in vitro method for the diagnosis or prognosis of neurodegenerative disorders based on new fragments of LRP (LRP1 and LRP2) in a biological sample, wherein if the level of expression of the concentration of the LRP fragment is significantly lower or higher (depending on the neurodegenerative disorder) as compared with the level measured in healthy controls, this is indicative that the subject is suffering the disease or has a bad prognosis. The proposed biomarker and a new nanosensor for the detection of the fragments in biological samples through Surface-enhanced Raman Spectroscopy (SERS) technology for the diagnosis of Major Depression in a early stage have been validated in a cohort of patients.
Nerea AlonsoFundación Biomedica Galicia SurNerea Alonso posted this:
IN VITRO METHOD FOR THE DIAGNOSIS OR PROGNOSIS OF NEURODEGENERATIVE DISORDERSIt is proposed an in vitro method for the diagnosis or prognosis of neurodegenerative disorders based on a new 48 KDa fragment of LRP1 (48 KDa – LRP1), wherein if the ratio of 48 KDa – LRP1 / proLRP1 level is significantly higher as compared with the level measured in healthy controls, this is indicative that the subject is suffering from major depression or has a bad prognosis. The proposed biomarker and a new nanosensor for the detection of the fragment 48 KDa–LRP1 and proLRP1 in biological samples through Surface-enhanced Raman Spectroscopy (SERS) technology for the diagnosis of Major Depression in an early stage have been validated in a cohort of patients.
Innovation Manager at Fundación Biomedica Galicia Sur
Medical University of ŁódźMedical University of ŁódźMedical University of Łódź posted this:
In vivo and in vitro experimental laboratory complexKeeping animals to research projects as well as own cultures. Cytotoxicity of a medical device in the form of an extract using in vitro assays: NRU, MTT, XTT, colony formation. Research projects in the field of neurology, orthopedics, toxicology, experimental surgery, oncology, metabolic and behavioral research (AnyMAZE, Morris pool, the cage of fear, IntelliCage) Conducting studies using GMOs. Training in procedures on laboratory animals. Renting test equipment.
Jagiellonian UniversityJagiellonian UniversityJagiellonian University posted this:
In vivo delivery system of the DNA modifying enzymesThe subject of the offer is a new method of in vivo genome editing with the use of hybrid nucleases, such as ZFN, TALEN and the CRISPR/Cas9 system, delivered to target cells by EVs derived from stem cells in serum-free conditions and defined as the RNA-containing vesicles expressing stem cells surface markers: CD90, CD105, CD147, CD309 (in more than 20% of RNA-positive events) and lack of expression CD45.
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
In vivo estimation of the fatty acids profiles of fish muscleIn vivo estimation of the fatty acids profiles of fish muscle CSIC has developed a method to predict the fatty acid profile of fishes, that can be applied on the living organisms, avoiding the need of sacrifice. This allows for a periodic monitoring of profiles in individuals and populations, being therefore a method of great interest in aquaculture or research of wild populations. Industrial partners in the field of aquaculture are being sought to collaborate through a patent licence agreement for its use and exploitation. An offer for Patent Licensing
University of WaterlooUniversity of WaterlooUniversity of Waterloo posted this:
In-vehicle detection of distracted driving using mmwave radar technologyBackground Distracted driving is a serious problem that can lead to fatalities. Identification of distracted driving is commonly performed with machine learning methods using cameras. The use of cameras is invasive and requires significant amounts of processing power to be performed in real time. Additionally, current solutions lack the ability to rapidly calibrate to different operators. Mmwave devices require smaller data input sizes, potentially allowing for rapid calibration of devices before use, in addition to being non-invasive since no optical data is recorded. Mmwave devices also generate a 3D scattered image of the interior of the vehicle, which gives more spatial information than optical imaging, which generates a 2D image, potentially allowing for more precise classifications given more identifiable information.- Maria João CardosoInstituto de TelecomunicaçõesMaria João Cardoso
Intellectual Property and Technology Manager at Instituto de Telecomunicações
View ProfileMaria João Cardoso posted this:
Increasing the information capacity of optical communications through embedded data modulation over pilot symbolsMethod to perform modulation over pilot symbols in communications systems employing quadrature amplitude modulation (QAM). It allows to either increase the delivered bit-rate of the transmission system while keeping the same operating bandwidth and/or reduce the required signal-to-noise ratio (SNR) for error-free operation. It does not incur performance penalty or added computational complexity.
Intellectual Property and Technology Manager at Instituto de Telecomunicações
- University of WaterlooUniversity of Waterloo
University of Waterloo posted this:
Indoor 5G wireless transmission over powerlinesBackground To provide the best 5G service, wireless service providers deploy Centralized Radio Access Networks (C-RAN) in which digital baseband processor units (BBUs) and their associated remote radio units (RRUs) are detached from each other and are connected by a fronthaul transport fiber-optic link. 5G signal has limited indoor coverage due to its high frequency and therefore, multiple RRUs must be deployed in a building for indoor users. Providing indoor 5G access for apartments in a building where there are no fiber infrastructure in place is therefore a major challenge.
University of Porto posted this:
Indoor environmental quality (IEQ) system and DBT platformThe present invention consists in a complete Indoor Environmental Quality (IEQ) system designed to evaluate and summarize the quality of dynamic indoor environments. The system uses a variety of high-precision sensors to collect environmental data, which is subsequently processed by a set of proprietary algorithms. The information is presented on a specially designed online visualization platform, enabling different stakeholders—technicians, building management entities, and end users—to easily interpret the data. The invention as a whole is a comprehensive system that efficiently gathers, analyzes, and presents relevant indoor environmental data.
IMDEA Energy posted this:
Indoor testing of materials, solar concentrators, receivers, PV modules and daylighting devicesHigh-flux solar simulator (HFSS) to conduct research on synthesis and surface treatment of new materials is offered. High-flux solar simulators are specifically designed to recreate the high radiation intensity distribution usually met in concentrating solar systems.We are looking for commercial agreement with technical assistance and research cooperation agreement. Application in thermal electricity generation, solar thermochemistry to produce fuels and commodities, or synthesis and surface treatment of materials. High concentration photovoltaic systems usually operate above 100 kW/m2. High flux solar simulators are designed to recreate the high radiation intensity distribution usually met in concentrating solar systems.
Fabian BelinLuxembourg Institute of Science and Technology (LIST)Fabian BelinPartnerships Development & IP Valorization at Luxembourg Institute of Science and Technology (LIST)
Fabian Belin posted this:
Industrial production of humic and fulvic acid from biomethan digestateAnaerobic digestion is a process able to degrade organic waste to methane using a diverse microbial community. However, not all organics present in the feedstock can be biologically degraded and the undegraded fraction are disposed to fields or incinerated. This fraction, called the digestate, is underexploited and represents an interesting source of humic substances as they remain undegraded during the AD process. Our solution consists of a series of process to extract and concentrate those humic substances, specially fulvic acid. The first step is the mechanical separation of the liquid and solid phases. Then the liquid fraction undergoes a serie of filtration to remove inorganic precipitates, large particules and impurities. Then the concentration is done by reverse osmosis where the water is removed, and the humic substance solution retained. This technology allows a recovery of 60% of the humic substances in a solution containing at least 50% of fulvic acids. Further concentration steps can be done if necessary to obtain a solution with a minimum concentration of 12% w/w.
Partnerships Development & IP Valorization at Luxembourg Institute of Science and Technology (LIST)
Yeda posted this:
Inertial NEMS for Nanosensor Applications Based on Inorganic NanotubesInertial sensors for motion detection are being incorporated into an increasing number of portable devices, including diverse IoT applications, mobile phones, wearable electronics, automotive systems and medical diagnostic sensors. The current size reduction trend in electronics, requires incorporation of reliable nanoelectromechanical systems (NEMS) into nanosensors, yet market applications of NEMS are currently limited by high costs of fabrication and inconsistent quality. A new technology developed by a group of researchers from the Weizmann Institute, provides a unique, highly reproducible structure for inertial nanosensors, with high durability at the nanoscale and with a detection mechanism based on the piezoresistive effect. The invention further extends application opportunities of extremely small portable electronics, which, with the increasing use of spatial awareness in reduced size electronics and IoT, is expected to witness increasing market demand.
