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Radoslaw Rudz posted this:
Hydrogel hybrid material for the reconstruction of bone defectsThe subject of the offer is an injectable, hydrogel hybrid material that can be used to construct a bioactive cell scaffold of a minimal invasivity. This scaffold may be located in place of a bone defect thus enabling reconstruction of bone tissue. Application: in tissue engineering for the reconstruction of orthopedic and dental bone defects.
Other at Jagiellonian University
Universidad de Granada posted this:
Hydrogels for the production of artificial tissue with enhanced mechanical propertiesA method for the preparation of hydrogels suitable for producing artificial tissues has been developed. The method combines fibrin, fibrinogen and short-chained peptides, which interact to enhance cell adhesion and proliferation. The resulting tissues could be used as a medicine for organ regeneration, and could restore the functional activity of a damaged or diseased organ.
Air Products posted this:
Hydrogen Storage Liquid has 3X the Energy Density of Lithium Ion BatteriesThis product delivers hydrogen with an extra degree of safety directly to fuel-cells on-demand. New designs are enabled since this "Liquid-Carrier for Hydrogen" is stored in tanks of any shape. The economics of this system have been validated by DOE and is among the least expensive methods of high-volume hydrogen storage. When loaded with hydrogen from renewable sources this technology delivers a complete green solution since the carbon portions of the molecules are completely re-used. With a well-to-wheels efficiency comparable to gasoline or EVs, this technology can deliver world-class efficiency.
Tech Transfer CIIMARCIIMAR - Interdisciplinary Centre of Marine and Environmental ResearchTech Transfer CIIMARBusiness Development Manager at CIIMAR - Interdisciplinary Centre of Marine and Environmental Research
View ProfileTech Transfer CIIMAR posted this:
Hydroxypheophorbide compounds as lipid-reducing agentsThe technology relates to hydroxypheophorbide compounds with bioactivity towards obesity and obesity-related co-morbidities. The compound may be used in the therapy or treatment of obesity, an obesity-related disorder, an obesity related disease, being overweight, an obesity-related condition, or lipid obesity disorders.
Business Development Manager at CIIMAR - Interdisciplinary Centre of Marine and Environmental Research
Universitat de València posted this:
HyLED optospintronics devicesThe most innovative aspect of this innovation is that provides new optospintronic devices with low emission threshold voltages. Also, the new devices have the following advantages: Efficiency: light emission threshold voltages from 2 V. Stability: use of air-stable electrodes, with high work function. Spin valve properties (magnetoresistance): control of electrical properties by means of magnetic fields, for example light intensity and colour. Low cost: manufacture with commercial and readily available materials, using soluble deposition methods, much cheaper, and viable on a large scale, that evaporative deposition methods.
Taras MaiulaOtava Research InstituteTaras Maiula posted this:
Hyperpolarization-Activated Cyclic Nucleotide Gated Channel Blocker LibraryThe hyperpolarization-activated cyclic nucleotide-gated #HCN channels are voltage-gated ion channels that play a vital role in regulating the activity of many cell types. Extensive research has shown that HCN channels may be a valuable target for the treatment of a number of neurological disorders. The Hyperpolarization-Activated Cyclic Nucleotide Gated Channel Blocker Library by Otava Chemicals https://bit.ly/3CBSKDK may be the perfect basis for antianginal, antiarrhythmic, neuropathic, etc. research and drug discovery projects.
Head of the QC department at Otava Research Institute
Yeda posted this:
Hyperstable Serum Albumin Variants for Microbial Mass ProductionSerum albumins are essential in a wide variety of molecular and cellular applications, including in the medical, biotechnological and cultivated meat industries. Albumins, however, are currently sourced from animal serum, raising significant concerns about reproducibility, scalability, and ethics. To address these issues, Prof. Fleishman and his team have designed and validated improved and boiling-resistant serum albumin variants that can be efficiently produced by bacteria.
Meghan Meyer posted this:
Hypothesis Generation- System with the ability to monitor the internet and other data continuously, discover hypotheses potentially explaining data, and notify users of identified and potential threats - Scalable, automated, theoretically sound method with wide-ranging national security and other applications. - Method is executable in real-time or near-real time, scalable to large applications, and places less pre-set boundary limits on search capabilities when compared to other current methods
Other at Georgetown University
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Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC posted this:
IchnaeaA Software System for the Microbial Source Tracking Problem
- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
ICHNAEA A Software System for the Microbial Source Tracking ProblemA software system for the Microbial Source Tracking (MST) problem has been developed in order to solve the problems of the current predictive models. It provides the accuracy and the precision of the prediction, the estimation for both the degree of dilution and the age of the pollution for the analyzed example. Partners to license the system and/or to establish commercial agreements along with technical cooperation are sought.
Aia Malik posted this:
iCRT - a novel encapsulation and controlled release platformiCRT is a novel and proprietary platform developed in the UK - the platform was designed to tackle difficult actives and complex formulations. It uses inorganic materials to overcome the challenges experienced when using polymeric delivery systems.
Commercial Development Manager at Lucideon
Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRIUniversidad de Alcalá-OTRI posted this:
ICT applications based on QR codes and RFID in teaching and research laboratories.A research group of the Department of Signal Theory and Communications at the University of Alcalá is developing Apps which allow improve the performance of the students and researchers in the measure and characterization of RF devices, by the description of the devices and the management of the necessary instrumentation. The group is looking for companies in the technology and telecommunications sectors to reach collaboration, and commercial agreements with technical assistance.
InKemia Green Chemicals, Inc.InKemia Green Chemicals, Inc.InKemia Green Chemicals, Inc. posted this:
Identification of high performance green solventsInKemia Green Chemicals has developed one of the world’s largest greener and safer solvent libraries containing hundreds of solvent solutions. We can work with you to address your challenges related to solvent performance by identifying an alternative green solvent that allows for enhanced performance or integrating an alternative solvent into a commercial product or process.
CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas posted this:
Identification of particles and/or cells in suspension using a mechano-optical systemCSIC has developed a sample analyzing system that can identify particles and/or biological cells in aqueous suspension or in physiological medium. The system allows simultaneously measuring the mass and light scattering of the particles in suspension in real time. This technology has been used to distinguish different cell lines, making it useful for diagnosing diseases. Industrial partners manufacturers of lab equipment are sought to collaborate through a patent license agreement. An offer for Patent Licensing
- Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRI
Universidad de Alcalá-OTRI posted this:
Identification of vehicle brands for traffic control and access control applicationsThe research group Intelligent Vehicles and Traffic Technologies of the University of Alcalá presents a device for recognizing vehicle brands based on a classification procedure of the manufacturer's logo. It is conceived as a complement to the classic optical systems of license plate recognition for applications of traffic management, access control or detection of infractions, providing useful information relative to the brand of the vehicle whose license plate, previously or subsequently, has been detected. The research group looks for companies / institutions / administrations in charge of traffic control, access control to restricted areas, as well as those in charge of integrating vehicle violation detection systems, for the signing of collaboration agreements, license agreements or commercial agreements with technical assistance.
Fabian BelinLuxembourg Institute of Science and Technology (LIST)Fabian BelinPartnerships Development & IP Valorization at Luxembourg Institute of Science and Technology (LIST)
Fabian Belin posted this:
iGuess4SECAP - An Energy Transition Platform for Sustainable Energy and Climate Action Planning for Cities and RegionsThe iGuess® platform framework has been developed since 12 years with different stakeholders at city and regional level and different applications in mind. The entire platform with all components is developed and owned by LIST. An enormous amount of knowledge in interoperable GIS based web platforms for a diversity of applications is contained at LIST level and can also be transferred. The increasing demand for sustainable energy solutions and the urgent need to combat climate change have made renewable energy a crucial aspect of urban development. Cities must transition to renewable energy sources and integrate them into their energy systems. However, the process of planning and implementing renewable energy projects in urban areas can be complex and challenging. It requires holistic and sustainable approaches which can only be delivered by in- depth/deep technologies, such as interoperable web- and cloud-based platforms, integrating a diversity of data and IoT sources, simulation and forecasting tools, as well as complex 3D-4D visualisation tools, in order to develop and implement decarbonisation strategies across the globe for cities, regions and nations.
Partnerships Development & IP Valorization at Luxembourg Institute of Science and Technology (LIST)
Servei de Gestió de la InnovacióUniversitat Politècnica de Catalunya - UPCServei de Gestió de la InnovacióLicensing Manager at Universitat Politècnica de Catalunya - UPC
View ProfileServei de Gestió de la Innovació posted this:
Image processing method for glaucoma detection and computer programWe have developed a new algorithm for ordering anterior chamber OCT images in such a way that it is possible to classify them, in a fully unsupervised manner, in meaningful groups according to relevant features. We have tested the algorithm with a large set of images classified by two expert ophthalmologists, and with a larger set of annotated images. We have verified that the separation in the different classes defined by the ophthalmologists (closed, narrow, open, and wide open_ figure 6) is similar when using the manually extracted features, or when using the features that are returned by the unsupervised algorithm (View figures). Therefore, the abstract features generated by the algorithm provide novel tools for assessing OCT images of the anterior chamber. They can be used for direct classification of the images and, furthermore, they can be linked to established quantities used for characterizing diseased eyes (like chamber depth, iris-corneal angle) resulting in an automatic detection system. As the algorithm is fully unsupervised, it can be easily automated and set up in OCT imaging systems to aid technicians and doctors in an early diagnosis. The two main advantages of the algorithm demonstrated here over previous works are that it doesn’t need any ground truth or gold standard for training, and it does not rely on specific landmarks; thus, it can analyze images in which relevant landmarks are not visible or not easy to locate.
Licensing Manager at Universitat Politècnica de Catalunya - UPC
University of WaterlooUniversity of WaterlooUniversity of Waterloo posted this:
Image processing optimizationBackground Memoization is a computing optimization technique that is used to speed up computer programs by having function calls avoid repeating the calculation of results for previously-processed inputs. Traditional memoization techniques have mostly failed to deliver tangible performance improvement in practice due to the generality of the techniques and lack of a priori knowledge about the characteristics of the input data or algorithms.
- University of WaterlooUniversity of Waterloo
University of Waterloo posted this:
Imaging amyloid beta in the retinaBackground Amyloid Beta protein is a marker for Alzheimer’s disease. Currently the only definitive test occurs during an autopsy. There are other forms of dementia that have similar symptoms to Alzheimer’s but which cannot be ruled out while the patient is still alive. If there were a means for earlier detection of the Amyloid Beta protein then it would be possible to properly diagnose patients with Alzheimer’s disease and start treatment at an earlier stage. This would lead to an improved quality of life for the patient and better longitudinal assessment of the effects of treatments on Amyloid beta, both in humans and animal models. - CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Imaging analysis of the zebrafish escape responseThe CSIC has developed a procedure and system for kinematic analysis of the stimulus-evoked escape response in adult zebrafish. The procedure falls within the field of image analysis using algorithms. Research centres and Industrial partners from pharmaceutical companies are being sought to collaborate through a patent licence agreement.
Yeda posted this:
Imaging Platform for IBD Drug DiscoveryInflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal (GI) tract, resulting in its damage and gut barrier dysfunction. These chronic conditions are treatable but not curable, dramatically decrease the patient’s quality of life and affect approximately 1.6 million Americans. The teams of Profs. Geiger and Elinav designed a high-throughput screening platform for molecules that affect the intestinal epithelial barrier and identified specific molecules that can be used as potential drugs to treat IBD.
UNIVERSIDAD DE BURGOS posted this:
Immobilization of glucose-oxidase for oenological application to obtain wines with low alcohol contentResearchers at the University of Burgos have developed a technology of immobilization of glucose-oxidase that reduces the amount of glucose available in the must for reducing the alcohol content in wine.
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Immunoassay for detection of Pseudomonas aeruginosa Quorum Sensing moleculesCSIC has developed an immunochemical method for diagnosis of infections produced by Pseudomonas aeruginosa targeting the main signaling molecules of the pqs Quorum Sensing system. The immunoassay is fast and efficient, with low LOD and adaptable to point-of care devices. Industrial partners from the pharmaceutical or diagnostics industry are being sought to collaborate through a patent licence agreement.
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Immunoassay for rapid diagnosis of infectious diseases caused by Pseudomonas aeruginosa CSIC, CIBER-BBN and UAB have developed an immunochemical method for diagnosis of infections produced by Pseudomonas aeruginosa. The immunoassay is fast and efficient, with low LOD and adaptable to point-of care devices.
UACOOPERA University of AveirouacooperaUACOOPERA University of Aveiro posted this:
Immunoglobulin Y Purification, Its Products And UsesThis invention describes a purification process of immunoglobulin Y from egg yolk in three stages, by applying precipitation methods, liquid-liquid extraction and ultracentrifugation. The present process allows to obtain immunoglobulin Y of high quality and with a purity >95%, in a simple and economic way, and applicable at an industrial scale.
Technology Transfer Office at uacoopera
University Hospital Hradec KrálovéUniversity Hospital Hradec KrálovéUniversity Hospital Hradec Králové posted this:
Immunosensor for Detection of Inflammation in Amniotic FluidA point-of-care test based on electrochemical immunosensor for simultaneous determination of three significant inflammatory markers. Preterm Premature Rupture of Membranes (PPROM) is a pregnancy complication. In this condition, the sac (amniotic membrane) surrounding the fetus breaks (ruptures) before week 37 of pregnancy. Once the sac breaks, pregnant woman has increased risk for infection. PPROM complicates 3 – 4% of all pregnancies and is up to 1/3 complicated by microbial invasion of the amniotic cavity (MIAC) leading to infection in amniotic fluid (AF) and development of intra-amniotic inflammation. Although this complication is usually asymptomatic, it is a major cause of preterm birth and neonatal morbidity and mortality worldwide. Neonates from these pregnancies are at increased risk of developing neonatal sepsis and impaired psychomotor development and other sometimes lifelong health consequences. Our invention is point-of-care test (POCT) based on electrochemical immunosensor for simultaneous detection of three inflammatory protein biomarkers with high predictive value in AF collected by amniocentesis. The aim of the test is to confirm intra amniotic inflammation. The entire biosensor consists of an immunosorbent magnetically active microparticles modifed with specific antibody. After capturing the protein biomarker by the immunosorbent, the bioconjugate (IgG antibody conjugated with an electroactive indicator, specifically quantum dots or gold nanoparticles) is added. A final measurable signal proportional to the concentration of the inflammatory protein biomarker is provided by metal ions released from the electroactive indicator. Disposable screen printed three electrode sensors are used for simultaneous electrochemical analysis. Clinical relevance of selected protein biomarkers was determined based on the results of proteomic and antibody studies of AF of pregnant women with PPROM. Advantages POCT enables to speed up the process of confirmation or elimination inflammation in AF and can be easily performed and evaluated in minutes beside the patient´s bed and thus enables personalised approach to therapeutic intervention of the pregnant woman. Currently, determining the MIAC is not specific enough and is very time consuming and technically demanding. It is based on combination of cultivation and molecular methods. Further research is focused on test verification in cervicovaginal fluid to avoid amniocentesis.
RAMOT at Tel Aviv University Ltd.RAMOT at Tel Aviv University Ltd.RAMOT at Tel Aviv University Ltd. posted this:
Immunotherapy for Stroke and Cognition in a Cerebral Amyloid Angiopathy Animal ModelCerebral amyloid angiopathy (CAA) is due to amyloid accumulation in the vessel walls leading to hemorrhagic stroke, and cognitive impairment. There are no available treatments to specifically reduce the risk of CAA. In this research we aim to assess brain tissue damage and cognitive impairment resulting from CAA in animal model and to investigate a novel approach to immune therapy. Methods: We have shown that nasal vaccination with a proteosome adjuvant (Protollin) that is well tolerated in humans, decreases amyloid plaques in an Alzheimer’s disease mouse model. It was recently reported that an overexpression of TGF-?1 under the control of an astrocyte promoter GFAP in mice results in CAA. TGF-?1 mice were nasally treated with Protollin on a weekly basis starting at the age of 13 months for three months. Following treatment animals were subjected for MRI and cognition analysis. Results: Here we show that nasal Protollin activates perivascular macrophage and potently decreases vascular amyloid in TGF-?1 mice. Using MRI we found that while PBS treated animals showed a significant enlargement of the lateral ventricles area, Protollin prevents further brain damage and prevents pathological changes in the blood-brain barrier. Vascular risk factors have been found to be associated with vascular dementia. Using an object recognition test and Y-maze, we found significant improvement in cognition with the Protollin treated group. Interpretation :Our study demonstrates that activation of macrophages by Protollin is a novel approach to reduce microhemorrhage, prevent stroke and improve cognition in a model of cerebral amyloid angiopathy. Project ID : 10-2011-259- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Improved bucket to protect biological tissues in immunohistochemical analysisImproved bucket to protect biological tissues in immunohistochemical analysis CSIC and the Miguel Hernández University have developed a bucket to be used in multiple in vitro analysis of biological tissues that fixes the samples for a safe transport between plate wells. Its improved structure facilitates an efficient use of the reactants, a maximized use of the grid surface, and the replacement of the grids in order to fit the requirements of the analysis. Industrial partners from the laboratory equipment industry are being sought to collaborate through a patent licence agreement for the commercialization of the device. An offer for Patent Licensing
