National Cancer Institute CRO Aviano

HPLC device for high-volume samples analysis

Posted by National Cancer Institute CRO AvianoResponsive · Innovative Products and Technologies · Italy

Summary of the technology

Fluidic device that allows high sample volume injection in HPLC systems and provides an automated purification step, reducing sensitivity problems and facilitating the analysis of extracted compounds from complex matrix.

Description of the technology

Technology Application:

i) Therapeutic drug monitoring and forensic medicine;
ii) Environmental analysis e.g. pollutants in air, water, soil;
iii) Food quality evaluation

Developmental Stage:

​​​A LC-MS/MS method based on this fluidic device has been validated in the laboratory and is currently used for therapeutic drug monitoring (Imatinib and Norimatinib) of cancer patients. Miniaturization and automation are required for commercial use. Patent opportunities are currently under evaluation.

Current development status

Laboratory prototypes

Desired business relationship

Technology development

Adaptation of technology to other markets

Other : Miniaturization

Technology Owner

National Cancer Institute CRO Aviano

Research Institute

Additional information (attached documents)

Related keywords

  • Analytical Chemistry
  • Medicine, Human Health
  • Pharmaceutical Products / Drugs
  • Agrofood Industry
  • Food quality and safety
  • Therapeutic services

About National Cancer Institute CRO Aviano

Research Institute from Italy

National Cancer Institute CRO-Aviano is an Italian public institute funded in 1984 and is committed to pursue excellence in all aspects of clinical oncology and management of health services. CRO is also an excellence in translational and clinical research activity. Our structure performs an average of 378740 patient exams/year, 8295 pts admitted/year (50% are extra-regional) for medium-long term stays and day hospital treatment. Scientific production sets above of 230 scientific papers in journals with Impact Factor (IF), ranking in the set of the 10% most cited papers in their respective scientific field, having a total IF>1000. Clinical trials average 60 per year.

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