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UACOOPERA University of Aveiro posted this:Production method of a new recombinant collagenase for collagens digestionMethod for obtaining collagenase with high collagenolytic activity, through a process based on recombinant DNA technology. This new process enables collagenase purification e isolation through a simple and economical procedure, obtaining an active enzyme with remarkable storage stability.
Technology Transfer Office at uacoopera
uacoopera posted this:Production of a novel collagenase and applicationsThe described process for collagenase production and purification is rapid, cheap and reproducible. The obtained product is highly active and stable for long period storage (in solution or lyophilised). The features of this novel product are, certainly related to a novel domain organization and architecture not yet described for other collagenases
Universidad de Alicante posted this:Production of briquettes for energy recovery of furniture waste with polyurethane foamsThe Research Group "Waste, energy, environment and nanotechnology" (WEEN) from the University of Alicante has developed a new compact material and a production process of briquettes of furniture waste. This process makes it possible to carry out the management and the energy recovery of this waste, avoiding the environmental problems associated with its landfilling and also making it easier to transport, handle and store. The briquettes obtained, show physicochemical characteristics similar to the conventional and they have a high energy density being able to be used as fuel for thermal power plants or industrial boilers. Companies in the waste treatment sector and the furniture industry that are interested in commercial exploitation of this technology through licensing agreements and / or technical cooperation are sought.
jaume mir posted this:Production of chymosins from camel and bovine origin using recombinant yeast strainsThe use of chymosins for the production of cheese and cheese derivatives from milk has been known for years, and nowadays this technique has completely substituted the use of calf rennet. Biochemize SL has developed several recombinant yeast and bacteria strains able to express chymosins from bovine (chymosin A and chymosin B) and from camel origin, with very good expression levels (between 0,1 and 3 g/L) and activity.
CEO at Biochemize SL
jaume mir posted this:Production of cis-3-hexenol and trans-4-hexenal from linseed oilCis-3-hexenol (mainly) and trans-4-hexenal are two molecules highly used in the cosmetic/fragances industry that are produced by chemical synthesis from non-renewable sources as petroleum. Recently, the need for this molecules obtained from renewable sources has been growing-up, but up to now the only source is the direct extraction from plants, that needs the use of high amounts of chemical solvents and thus is not an environmentally friendly and sustainable process. Anyway, the cis-3-hexanol and 4-trans-hexenal obtained by this method have a market cost much higher (from 30 - 50 USD/ Kg of synthetic molecules up to 350 - 400 USD/ Kg of natural origin/extracted molecules). Biochemize has developed a process for the renewable and sustainable production of these two molecules, through the use of recombinant microbial strains that express the genes that encode for the enzymes that are the responsible for the (metabolic bio) synthesis of both molecules in some plants that naturally produce it. Thus, Biochemize has developed a low-cost effective process for the natural (fermentative) production of cis-3-hexenol and trans-4-hexenal, from linseed oil and through the release of linulenic acid.
CEO at Biochemize SL
jaume mir posted this:Production of D-panose through an innovative microbial fermentation processD-panose (α-D-Glucopyranosyl-(1->6)-α-D-glucopyranosyl-(1->4)-D-glucose) is a high value tri-saccharide molecule that has been proposed as a low caloric content sugar (i), as a promoter for probiotics (ii) and having outstanding anti-oxidant. anti-tumoral properties (iii). Currently this rare sugar is obtained by chemical synthesis, and this is the reason for its extremely high cost/ price (1) and poor industrial uses (2). At Biochemize SL we have developed a (very simple) production process that leads the production of high pure (more than 99%) D-panose, through a microbial fermentation process using a recombinant bacteria strain engineered by us, at a significantly lower operational/production cost. We offer this process to be operated by/ be licensed to a manufacturing company operating in this area.
CEO at Biochemize SL
Consejo Superior de Investigaciones Científicas posted this:Production of high-affinity antibodies through the in vitro recreation of a germinal centerCSIC have developed a method for the in vitro generation of antigen-specific antibodies or cells producing thereof by means of the development of an in vitro germinal center useful to produce vaccines, immunomodulators or immunotherapies. Industrial partners from the biotechnology and/or pharmaceutical industry are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing
Consejo Superior de Investigaciones Científicas posted this:Production of isophorone derivatives by fungal peroxygenasesCSIC has developed a biocatalytic transformation of isophorone (3,5,5-trimethylcyclohex-2-en-1-one) and 4-hydroxyisophorone (4HIP) to selectively produce 4-hydroxyisophorone and 4-ketoisophorone (4KIP), valuable products for pharmaceutical, flavor and fragrance industry. The biocatalysts employed are unspecific peroxygenases from the fungi or recombinant proteins expressed in Aspergillus oryzae. Industrial partners from pharmaceutical, flavour or fragance industry are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing
Consejo Superior de Investigaciones Científicas posted this:Production of porous solids with embedded gases to be used as solid-gas nanocomposite materialsCSIC has developed a method for the production of nanoporous solids that contain gas inside their pores. The method is based on magnetron sputtering, but gas consumption is lower in comparison with conventional sputtering methods carried out in dynamic regime. Experimentally, layers of controlled thickness of these nanocomposite materials have been successfully obtained. Gas consumption during the production of these solids was only 0.5% of gas consumption in conventional magnetron sputtering in dynamic regime. Industrial partners from electronic or defence sectors or laboratory materials and chemicals products providers are being sought to collaborate through a patent license agreement. An offer for Patent Licensing
Graft Polymer UK Ltd posted this:Project: Innovative pilot production modified compounds by PE125 standard for multifunctional applications.Producing PE125 using GRAFTALEN™ MP-UHHD. Consumer properties, which should be taken into consideration: 1) The unique toughness of the material (the highest rate of all known polymers), namely, Over 160 kJ/m2 2) High abrasion resistance 3) Low friction coefficient (self-lubricating) 4) High resistance to chemically aggressive reagents (media) 5) High creep resistance (geometric stability) Ordinary way - This type of process is quite expensive. Production of PE125, in compounding with bimodal PE100, from 8 to 45% of supermolecular polyethylene is injected, reaching dispersion by multiple compounding (4 stages) in an extruder cascade (XXXXX technology). GRAFTALEN™ MP-UHHD (alloy) is a MELT-PROCESSABLE concentrate of UHMWPE on an HDPE matrix. As HDPE, you can choose the most affordable HDPE (pipe) grade. To obtain polyethylene according to the standards PE125 (with a minimum strength indicator MRS> 13.8-14 MPa, in comparison PE100 has MRS only 10 MPa), a significant improvement in the resistance against hydrostatic pressure is required. For a conventional bimodal HDPE, this indicator is difficult to achieve, since it directly correlates with the impact strength/density indicators and with simple extrapolation, it turns out that the required indicator for PE125 simply does not reach the bimodal HDPE matrix. Another problem - the difficulty in maintaining the geometric stability of the pipe (the thickness at the top of the pipe is often less than at the bottom) due to the sagging effect (the phenomenon of the gravitational flow of a polymer melt). This phenomenon is more pronounced for thick-walled pipes. The specific blend of HDPE with UHMWPE allows solving these problems above.
Benemérita Universidad Autónoma de Puebla posted this:PROSTHESIS VESTIBULAR WITH TECHNOLOGY (MEMS)A vestibular prosthesis includes micro-electric-mechanical (MEMS) sensors, gyroscopes in each sensitivity axis (X, Y, Z), accelerometers in each sensitivity axis (X, Y, Z) to detect an angular and linear movement providing displacement measurements, gyroscopes in each one of the spatial axes (X, Y, Z), a microprocessor connected to the MEMS sensors and producing an electric pulse pattern or a continuous galvanic current pattern, a conditioning unit that amplifies and conditions the microprocessor output to apply current to the stimulation electrodes, the microcontroller being configured to determine the displacement of the cupula and the otolithic mass, determine a membrane potential as a result of a displacement detected by the MEMS sensors by means of determining a transduction current, and determine an action potential discharge pattern for the primary afferent neuron,; which synapses with the hair cell by means of a mathematical model of the informative process of the vestibular mechanoreceptor.
Centre Technology Transfer CITTRU posted this:Protective coating for metal implants: effective protection against heavy metal ions release, high durability, simplicity of production and relatively low priceThe main innovative aspects of the invention are: •highly effective protection against corrosion of the implant surface in the environment of body fluids resulting in a significant reduction of the release of metal ions into the body; •high durability of the coating; •simple manufacturing method; •relatively low price.
Universidad de Alcalá-OTRI posted this:Protein separation by using anionic carbosilane dendrimers.BIODEN research group (Biomedical applications of dendrimers) from the Department of Inorganic Chemistry of the University of Alcala along with the research group of Micro(sep) from the Department of Analytical Chemistry and Chemical Engineering have developed a technology based on the use of anionic dendrimers as nanoadditives in capillary electrophoresis (CE) for protein separation, more specifically for obtaining protein profiles useful in food characterization. The groups look for companies of chemical, pharmaceutical or biotechnological sector to sign research collaboration agreements or license agreements.
- Creative ProteomicsCreative ProteomicsCreative Proteomics
Small and Medium Enterprise
Creative Proteomics posted this:Proteomic ServiceCreative Proteomics specializes in a full range of services to support various proteome-related researches from identification of single proteins to large-scale proteomic studies. We have one of the most advanced proteomics platforms in the world and our staff scientists are experienced proteomics professionals.
UACOOPERA University of Aveiro posted this:PSA purification and concentration from urine samples for non-invasive early stage diagnosis of prostate cancerNew method for the pretreatment of human urine sam-ples, comprising the simultaneous extraction, concentration and purification of the prostate-specific antigen (PSA), a prostate cancer biomarker. In this technology, aqueous biphasic systems composed of ionic liquids and salts are used. These systems allow the selective extraction of PSA and to obtain high con-centration/enrichment factors, enabling the quantification of PSA using less sophisticated, cheaper and more affordable equipment.
Technology Transfer Office at uacoopera
- Fundació UdG MedicinaFundació UdG MedicinaFundació UdG Medicina
Technology Transfer Office
Fundació UdG Medicina posted this:PSICODEM is a very simple software. It allows you to choose the most appropriate psychosocial intervention for people suffering from dementia, depending on their level of cognitive impairment and other signs and symptoms such as aphasia or anxietyIt is a very simple software. It does not needt to be installed, just needs internet access, together with a user name and password. It is very easy to use and very useful when professionals need to take quick decisions based on best existing evidence. They have to consider level of patient's dementia according to MMSE test and study their signs and symptoms in order to obtain the best psychosocial intervention that is recommended.
Consejo Superior de Investigaciones Científicas posted this:Purine derivatives for the treatment of neurodegenerative diseasesCSIC has synthesized several substituted purine derivatives that are capable of inhibiting the activity of the CDC7 kinase. This inhibitory activity makes them useful for the treatment of neurological diseases. The compounds developed are, therefore, a new therapeutic alternative for Alzheimer's disease, amyotrophic lateral sclerosis or frontotemporal dementia. Industrial partners from pharmaceutical industry are being sought to develop and commercialized the compounds through a patent licence agreement. An offer for Patent Licensing
University of Vigo posted this:Pyridazin-3(2H)-one Derivatives as Selective Inhibitors of Monoamine Oxidase-B Isoform (MAO-B)The pyridazine ring is a privileged fragment found in compounds with very different pharmacological properties, such as antihypertensive, antiplatelet, anti-inflammatory, antinociceptive, antidepressant, hypoglycemic, antiinfective or anticancer agents, many of them being pyridazin-3(2H)-one derivatives. The pyridazine ring is also included in polycyclic compounds acting as MAO-B inhibitors. However, simple pyridazin-3(2H)-one derivatives have not been described so far as selective MAO-B inhibitors. The present invention provides novel pyridazin-3(2H)-one derivatives substituted at C4, C5 or C6 with several dithiocarbamate moieties that selectively inhibit the MAO-B activity and whose structure is unrelated to those currently available.
- Yissum - Research Development Company of the Hebrew UniversityYissum - Research Development Company of the Hebrew UniversityYissum - Research Development Company of the Hebrew University
Technology Transfer OfficeView Profile
Yissum - Research Development Company of the Hebrew University posted this:Quantum Nano Materials for Photo-Catalytic ApplicationsComposition of metal-semiconductor nanoparticles for the generation of reactive species (radicals, peroxides) in solution. This project covers different embodiments that have other researchers involved on different subsets (therapeutics, photoinitiators). For example, there is a biological aspect, whereby a biological assay is a result of a pathway started with reactive species generation. Project ID : 9-2015-3191
Alexander Kvashnin posted this:Radar-type mm-range visualization systems for inspection systemsSystems for radar type visualization of the mm-range have been developed in the laboratory of the University (Russia). The systems are used for screening applications. They allow to determine objects hidden under the clothes and inside the baggage. They are safer in comparison with X-ray systems and are more sensitive to a number of X-ray-non-contrast materials. Developers are looking for partners to develop an industrial prototype of the visualization system and organize its serial production.
Director at Center for Technology Transfer and Commercialization of Novosibirsk State University
- Northeastern University's Center for Research InnovationNortheastern University's Center for Research Innovation
Northeastern University's Center for Research Innovation posted this:Rapid Gas-Phase Isotopic Labeling for Enhanced Detection of Protein ConformationsSeveral prior-art techniques such as ion mobility spectrometry and gas-phase HDX measurements have been used for assessing the conformational properties of gaseous protein ions. Most of these approaches comprise the use of ion traps or ICR cells where a gas is introduced and the ions are incubated with the gas. However, such approaches are associated with potential limitations such as extended gas-phase labeling time, complex exchange kinetics, and comparatively low gas pressure. This novel approach enables a rapid gas-phase isotopic labeling of protein ions for enhanced detection of protein conformations.
Radoslaw Rudz posted this:Reactor for spectroscopic studiesNovel HT-IRS 01 reactor, with unique characteristics, is dedicated to working in a transmission mode of optical spectroscopy (for example IR spectroscopy). It may be easily combined with mass spectroscopy or gas chromatography.
Licensing Manager at Centre Technology Transfer CITTRU
- Northeastern University's Center for Research InnovationNortheastern University's Center for Research Innovation
Northeastern University's Center for Research Innovation posted this:REAL-TIME ANOMALY DETECTION OF LARGE, DENSE CROWD BEHAVIOR, FROM VIDEO AND MULTI-SENSOR INFORMATIONCurrent methods for detection of crowd behavior are based on tracking individuals or virtual particles. Such assessments are highly prohibitive, preventing the real time and efficient analysis. Other approaches use comparisons of individual behaviors with normal patterns. However, these approaches are tedious and unreliable. This novel procedure allows for the use of a sensing system (comprising video and multi-sensor information) for real-time detection of the behavior of a large, dense crowd.
Barcelona Skin Genomic posted this:Recommendation of optimal combinations of natural active compounds to treat disease using a databaseBarcelona Skin Genomic (BSG) is developing a database that compiles information about the effects of different natural active compounds or plant extracts (more than 2500) on gene expression, on the levels of expression of interleukins and other molecules (more than 3400) and on treatment of different diseases (677). This database collects information from more than 5000 scientific articles, integrated by biologists and experts in life sciences and is updated on a monthly basis.
Universitat Politècnica de Catalunya - UPC posted this:Reconfigurable beam reflectarray antenna for frequencies in the range of terahertz and millimeter waveThe reflectarray antenna consists of a flat array of phase-shifter cells (reflectarray) illuminated by a feeder, which produces an electronically reconfigurable collimated or shaped beam, where the cells (3b) consist of several stacked layers of conductive elements (4c, 4e, 4d, 4f) on a dielectric substrate (7c, 7d) alternated with layers of liquid crystal (5c, 5d) and a conductive plane (9). Applying bias voltages in the conducting elements, the dielectric constant of the liquid crystal varies producing a phase shift of the reflected field in each cell, allowing for a electronic beam scanning or reconfiguration. Including multiple layers of conductive elements and liquid crystal, improves the bandwidth and the performance of the beam scanning or reconfiguration. The antenna can be applied to observation satellites, communications and security systems.
Christophe Auriant posted this:Reflux air condenser which solves water condensers' drawbacks without any performance loss.Reflux air condenser which solves water condensers' drawbacks without any performance loss. A reflux air condenser which can solve following water condensers' issues: -Need for a water supply. -High water consumption. -Can lead to local floods, especially for long lasting synthesis (overnight) -Congestion with water pipes. -High probability of cuts during water pipes plug in. -Progressive fouling by µ-algaes.
Business Development Manager at Ouest Valorisation
Consejo Superior de Investigaciones Científicas posted this:Regulatory compounds of synaptic transmission for the treatment of neurological diseasesThe CSIC and IRYCIS (Ramón y Cajal Institute for Health Research) have developed a group of compounds. These compounds have the ability to regulate the number of synapses that are formed between neurons, as well as the probability that neurotransmitters are released from these, because they have the capability of modulate the interactions that take place between the regulatory proteins NCS-1 and Ric8a that regulate these two independent processes. Due to these neuromodulatory properties, these compounds are useful for the treatment of neurological diseases as Alzheimer's disease, Huntington or Parkinson's diseases among others. Industrial partners from the ophthalmic or pharmaceutical industry are being sought to collaborate through a patent license agreement. An offer for Patent Licensing
University of Vigo posted this:Removable and reconfigurable system for corner connection of square tube profilesThis removable connection system can be adapted to the size of the section, by adjusting the length of the connecting bolts, using the same flanges. Is usable for a wide range of standard profiles, which avoids the need for a flange size for each profile section.