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Laser Consult Ltd. posted this:
Lightning conductor with upgradeable modular structureOur partner a Macedonian company has developed a modularly upgradeable lightning conductor with built-in early streamer emission device. Lightning conductors are designed to increase the efficiency of lightning attraction and to improve the radius of protection 1.5 - 3 times of a conventional lightning rod. The modular structure enables different functions for the product. The company is interested in finding suitable license partner.Universitat Politècnica de Catalunya - UPC posted this:
LIGHTWEIGHT NEUTRON DOSIMETERA lightweight cylindrical neutron dosimeter, of the Anderson-Brown type, able to work in continuous, quasi-continuous and pulsed neutron fields.Luxembourg Institute of Health posted this:
LIH383: Novel Modulator Of The Opioid System Regulator ACKR3LIH383 is a novel highly potent and specific negative modulator of ACKR3, developed by Dr Andy Chevigné, Head of Immunopharmacology and Interactomics, and Dr Martyna Szpakowska. It is an octapeptide (short chain of eight amino acids) with high selectivity and subnanomolar affinity for ACKR3. It was engineered by introducing a series of mutations to adrenorphin. Compared with other natural opioid ligands, its sequence (FGGFMRRK) confers it maximum specificity and affinity for ACKR3 and minimum selectivity and affinity for other opioid receptors. LIH383 therefore binds to and blocks ACKR3, thereby modulating the availability of opioid peptides that can bind to classical opioid receptors in the brain and potentiating their natural painkilling and antidepressant properties. LIH383 is therefore a positive regulator of the opioid system. In a nutshell, LIH383 presents the following advantages: > Subnanomolar potency > High selectivity for ACKR3 > Short chain (8 amino acids) > Easy to synthesise/customise- Luxembourg Institute of HealthLuxembourg Institute of HealthLuxembourg Institute of Health
Technology Transfer Network
Luxembourg Institute of Health posted this:
LIH383: novel modulator of the opioid system regulator ACKR3LIH383 is a novel highly potent and specific negative modulator of ACKR3, developed by Dr Andy Chevigné, Head of Immunopharmacology and Interactomics, and Dr Martyna Szpakowska. It is an octapeptide (short chain of eight amino acids) with high selectivity and subnanomolar affinity for ACKR3. It was engineered by introducing a series of mutations to adrenorphin. Compared with other natural opioid ligands, its sequence (FGGFMRRK) confers it maximum specificity and affinity for ACKR3 and minimum selectivity and affinity for other opioid receptors. LIH383 therefore binds to and blocks ACKR3, thereby modulating the availability of opioid peptides that can bind to classical opioid receptors in the brain and potentiating their natural painkilling and antidepressant properties. LIH383 is therefore a positive regulator of the opioid system. In a nutshell, LIH383 presents the following advantages: > Subnanomolar potency > High selectivity for ACKR3 > Short chain (8 amino acids) > Easy to synthesise/customise UACOOPERA University of Aveiro posted this:
LipidPro - Fluorescent dye for detection of lipid aggregates in living cells and other samplesFamily of dyes to be used in fluorescence microscopy imaging of cells in culture or entire organisms, including live cell imaging. The fluorophores are not toxic, and preferentially bind to lipid aggregates, such as intracellular lipid droplets. They also light up cells by binding weakly to several subcellular structures. Importantly, the fluorophores change color with the polarity of the environment and may be used to initially characterize alterations in organelle polarity. The most promising fluorophore, LipidPro, has been tested in fibroblast-based High Throughput Screens for the diagnosis of Faber’s disease.
Technology Transfer Office at uacoopera- CNIC (TTO)Spanish National Center for Cardiovascular Research (CNIC)CNIC (TTO)
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)
View ProfileCNIC (TTO) posted this:
Liquid biopsy for early detection of cancer or precision medicineScientists at EMBL-EBI, CNIC and CSIC have discovered a new type of telomere fusion that is not present in blood from healthy donors but can be detected well in the blood of cancer patients. They developed computational tools for the reliable identification of these fusions. Additionally, predictive models have been established that allow for the detection of the presence of a tumour using sequencing data from a blood sample. We hereby present an approach for a highly specific, minimally invasive and early detection of cancer. The sensitivity and false positive rate are comparable to recent liquid biopsy analysis methods. The performance of the tools is comparable across cancer stages. The tool has been validated using close to 10,000 whole genome sequencing datasets.
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC) Alfonso del Rey Pérez posted this:
Lithium filled nanocapsules for cancer treatmentCSIC through the Institute of Materials Science of Barcelona ICMAB has developed new carbon nanocapsules filled with enriched lithium compounds. These nanocapsules can be applied in Neutron Capture Therapy (NCT) for cancer treatment.
Technology Transfer Officer at ICMAB-CSICKyoto University posted this:
Liver-on-a-chip for Disease Modeling and Drug ScreeningDrug discovery is oftentimes hindered by inadequate disease models. For diseases affecting the liver 2D hepatocyte culture models are generally used which fail to recapitulate the organ functions and pathophysiologies. Organ-on-a-chip technique has recently gained attention for liver modeling, and several devices containing different liver cell types have been developed. The present invention is a liver-on-a-chip (LoC) device which contains hepatocytes and cholangiocytes (bile duct epithelial cells) therefore reproducing the hepatic region around the bile duct in 3D for the first time.Unismart - University of Padua Foundation posted this:
Living cell system of marine mammals for cell biology studies, toxicological tests and large-scale research applicationThe technology of S.S.S. consists in its being an "Integrated System", it allows to perform studies in multiple combinations between the 5 cell lines of the kit, giving the possibility to obtain species-specific biological responses (Tursiops vs Grampus vs Ziphius) or family-specific (Delphinidae vs Ziphiidae) or tissue?specific (skin vs muscle).Milou Klooster posted this:
Loadcarrier management with a smileRTI Blockchain is a disruptive, innovative solution to registrate all types of returnable transport items (RTI) with your value chain partners. Items such as crates, pallets, rolcontainers, gitterboxes, cilinders, reusable bottles etc. These could either be pooled items as non-pooled or own items.
CEO at RTI BlockchainUniversidad de Alcalá-OTRI posted this:
Location system and navigation assistance for blind people, using artificial vision.Robesafe group from Alcalá University is developing an assistance navigation system for blind people to guide them in structured indoor environments (such as corridors, distributors, rooms ...) and outdoor environments as well, using the merger between a GPS sensor and artificial vision. The system will show the path to follow to get to a destination, using acoustic information obtained by a synthesizer voice, similar to how the current GPS navigators do it. The group is interested in reaching commercial agreements with technical assistance with companies dedicated to the designing of mobility assistance systems for blind people.Benemérita Universidad Autónoma de Puebla posted this:
LOGICAL COUNTER OF SUBATOMIC PARTICLESA device for quantifying particles, which is characterised in that it comprises: a) an electronic system of signals produced by detectors reacting to transiting subatomic particles that are electrically charged and generate negative pulses, b) four detectors for fixing the discrimination voltage level, the duration time of the test and for obtaining the number of events per channel, the number of coincidences between the activated channels and the frequency of particles detected per time unit, c) a discriminator with a reference voltage selecting the detected events according to the fixed level, d) a memory module, e) a trigger module, and f) a coincidence logic module that makes the decisions for accepting the detected event or only increasing the counters of the channels that are activated and have information to process.uacoopera posted this:
Low Complexity Digital Filter for Chromatic Dispersion Compensation in Time DomainA group of researchers from a Portuguese university developed a method for chromatic dispersion equalization for coherent optical communication systems. The invention is targeted to equalize the the chromatic dispersion impairments in high-speed coherent optical communication systems. This method will allow a minimization of the hardware and power consumption requirements of electronic devices in real-time implementations, due to its low complexity when compared with existent solutions. The University is seeking for optical telecommunications industries which may pretend to include this technology on their portfolio, in order to minimize the hardware and power consumption requirements of coherent transceivers.CSIC - Consejo Superior de Investigaciones Científicas posted this:
Low cost and reusable, non-invasive wireless chemical sensor for biological fluidsLow cost and reusable, non-invasive wireless chemical sensor for biological fluids Researchers from the Spanish National Research Council (CSIC) have developed a novel wearable sensor technology, which is suitable to detect and monitor in a non-invasively-way metabolites and biomarkers such as glucose, lactate and/or alcohol. The sensor is based on an electrochromicelectrochemical and wireless optical sensing basis, and is suitable to be used on biological fluids (included human or food one). Its mass-production capability by using conventional screen-printing process enables their easy and low-cost integration in multiple form factors. Industrial partners interested on mass production of electrochemical sensors for smart patches, food packaging and textiles (clothes and shoes) applications are being sought to exploit the technology through a license or collaboration agreement. An offer for Patent Licensinguacoopera posted this:
Low Cost Minimum Quantity of Lubricant SystemA group of researchers from a Portuguese university has developed a system of "Minimal Quantity of Lubricants" fully functional and automated. The term MQL, "Minimal Quantity of Lubricant", refers to the use of a low lubricant flow (10 to 100 mL / hr) through a high pressure fluid (compressed air). This system is an alternative to most lubrication systems used in machining operations, with both economically and ecological level advantages, contributing to sustainable manufacturing. This system stands out for its optimal functioning, automation, low cost and good portability. It allows a good lubrication and a good cooling of the machined piece, dry chips, a cleaner desktop, thus ensuring a higher yield and environmental improvement.Universidad de Alicante posted this:
Low cost sensors for the detection of gaseous hydrogen• New simple preparation method which does not require sophisticated instrumental techniques. • The procedure use low-cost materials and optimizes the loading of the metals employed. • This technology is efficient, producing robust and reliable sensors with high signal-to-response ratio and low cost. • The CNT and nanoparticle suspensions needed are stable and may be stored over long periods of time.Dr.Shivraj Dasari posted this:
Low Cost Species Specific Dengue Panel(Densure1-4) for Point of Care Testing in Low resource SettingsOur NAAT-LAMP Densure 1-4, panel can evaluate Four species of Dengue virus, simultaneously in about an hour. The idea is to have single panel to accurately diagnose specific species which is causing the infection, so that the clinician can start the Treatment at the earliest which is very personal and specific to the patient.
CEO at SLS cell cure technologies Pvt. LtdUniversidad de Alicante posted this:
Low cost system for measuring vibrations through camerasAmong the current methods for measuring vibrations, accelerometers are traditionally preferred. Nevertheless, these methods are contact devices, which may be difficult to use when the specimens not accessible due to the object itself or the surrounding conditions (inaccessibility, damage risk, etc.). Alternatively to the accelerometers, Doppler vibrometers are often used as non-contact devices. Although they provide very accurate result, they result expensive and non-cost effective for many applications. Additionally, both of them only provide a single point measurement while our method permits, not only monitoring the process but, with the vibration map, obtaining the vibration frequencies of all vibrating objects in the scene at a glance.CSIC - Consejo Superior de Investigaciones Científicas posted this:
Low energy and high efficiency hydrogen generation through water electrolysisLow energy and high efficiency hydrogen generation through water electrolysis CSIC and the Polytechnic University of Valencia have developed a water electrolysis system that, thanks to an innovative structure of the electrodes, allows concentrating the electric field in the desired areas in order to facilitate the dissociation of the electrolyte, maximizing the efficiency of the reaction and reducing the voltage requirement and the energy consumption. Industrial partners are being sought to collaborate through a patent licence agreement to use the technology in the electrochemical industry or in the production of hydrogen through water electrolysis. An offer for Patent LicensingCracow University of Technology posted this:
Low energy building design and thermal refurbishment of existing buildingsOUR MAIN GOALS Tools and good practice procedures for low energy building design, enabling to reduce demand on heating and prevent cooling demand while maintaining high indoor air quality. Because of the big volume of poor quality prefabricated apartment buildings, that still exist in Poland, one of our goals is also to elaborate a scenario of holistic revitalisation of those buildings in accordance with the requirements of sustainable development.Heflen International Limited posted this:
Low Energy High Efficiency Transfer Spray GunHeflen low energy spray gun betters the BAT requirements, has a 85%+ transfer efficiency; services the Paint and Nano coating industry a unique control method to reduce surface bounce back and reduction in an overall carbon foot print for its users. Its world patented technology has proven its ability to reduce the risk of exposure to the end user and the environment bringing a safer method of application for all coatings.RAMOT at Tel Aviv University Ltd. posted this:
Low energy laser bio-stimulation of bone marrow stem cells for the treatment of myocardial infarctionHeart diseases are the leading cause of death worldwide. Low energy laser (light) irradiation has been shown to have bio-stimulatory beneficial effects on various biological processes in vitro, in vivo and also in clinical trails. We have explored the beneficial effects of light therapy (LT) on stem cells in the bone marrow in order to determine its potential application as cell therapy for the heart post myocardial infarction (MI). Preliminary results have shown that in the infarcted rat heart model the application of LT to the rat bone marrow (BM) in the hind leg 10 min and 4 hrs post MI caused a significant reduction of 79% and 75 % respectively in the scar tissue formed after MI. This is a novel, simple and non-invasive approach to improving heart function after heart attack in patients, and may also serve as a basis for cell therapy of other diseased organs. The fact that LT demonstrated efficacy in scar reduction 4 hours post MI, indicates its clinical relevance to treat patients post MI. Project ID : 2-2011-143Universitat Politècnica de Catalunya - UPC posted this:
Low frequency Non-Intrusive built-in strategy to test and characterize RF and mmW integrated analogue circuitsSet of procedures and circuit sensors to embed within high frequency analogue circuits (e.g.: RF, mmW), whose goal is to enhance either test production or self healing strategies to reduce performance spreading and to enhance yield. The technique is based on measuring the temperature at selected locations of the circuit under test with the goal of extracting information about the performances of the individual blocks that constitute a complete system (e.g. low noise amplifier, power amplifier, etc). Partners to further develop the system and/or to establish commercial agreements along with technical cooperation are sought.BSUIR R&D Department posted this:
Low-altitude radio altimeters in the millimeter wavelength range for use in aviationUniversity has developed a range of high-precision low-altitude radio altimeters in the millimeter wavelength range. Delivery of the finished product. Product development for specific customer requirements.Universidad de Alicante posted this:
Low-cost sensorised device for (tele-)rehabilitationThe "Human Robotics" research group at the University of Alicante has developed a sensorised device for the rehabilitation of a body limb (preferably the upper limb). This device consists of an elastic textile covering and inertial and electromyographic sensors attached to it, with which the patient's improvement will be monitored and evaluated, also allowing to adjust the exercises of simulated games, based on virtual reality and/or augmented reality applications. The system constitutes an integrated rehabilitation tool for people with mobility problems in the upper limb, easy to use and based on user motivation. The technology, which is protected under patent application, has been developed at laboratory scale and a prototype is available for demonstration. Companies interested in the commercial exploitation of the device are sought.Universitat Politècnica de Catalunya - UPC posted this:
Low-power FOCV MPPT controller with automatic adjustment of the sampling time and periodA new simple control scheme for dynamically adjusting the sampling time and period of a Fractional Open Circuit Voltage (FOCV) MPPT controller has been developed and patented. Partners to further develop the system and/or to establish commercial agreements along with technical cooperation are sought.Glenn Halliday posted this:
LSF: B2B Chemtech, UK & NL, Angel round with lead investor, ≈40% funding securedLSF is a Chemtech business based in Amersham, UK, with extensive industry experience. A B2B operation, generating revenue from customers Proof of Concept (PoC) testing and a roadmap to deliver the first demonstrator facility. The LSF process accepts used solid or liquid, hydrocarbon-containing, feedstock materials. The process gasifies the feedstock and then using a liquid electrolyte, oxidation and saturation reactions are initiated. These reactions produce a recovered, saturated condensate and a solid, raw Carbon Black output. LSF's recovered condensate is of a higher quality and has far lower contaminants than its competitors and the rCB has been tested as suitable for vehicle and industrial rubber components. LSF has patented the core technology and the novel application of electrochemical processing of hydrocarbon-containing feedstocks. UK & US patents granted with EU patent expected to be granted in Q1, 24.
Co-Founder & COO at Low Sulphur Fuels LtdLisa Clara posted this:
Lysozyme (Food Grade)Lysozyme, often touted as the body's natural antibiotic, is a powerful enzyme inherently produced in the mucosal linings of our body, including the saliva, tears, and milk. This enzyme plays a pivotal role in our immunity by breaking down the cell walls of harmful bacteria, thus acting as our body's frontline defense. With such a potent bacteriolytic capacity, the idea of harnessing its potential for food preservation is quite intriguing.
Marketing Manager at Creative Enzymes
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Brunel University London posted this:
Magnesium Alloys with Improved CastabilityMagnesium alloys are lightweight and so provide the best solution for reducing weight in the transport sector. However increasing the use of these alloys to replace steel has been hampered by their lack of ductility and low yield strength. This is due to the large grain structure, defects and inter‑metallic particles formed during casting. New magnesium alloys produced using a novel Magnesium Boride grain refiner have a much finer structure with fewer defects, resulting in improved ductility and strength in addition to reduced defects during casting and ease of casting complex shapes.