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xrqtc posted this:
Polymorphism Prediction in Crystal Systems of Technological InterestCurrent polymorphism studies are being carried out using one of the following three alternatives: atom-atom potentials, DFT (Density Functional Theory) calculations and ad-hoc potentials. However, all of them have serious disadvantatges. 1) with software that uses atom-atom potentials: Advantages: fast and capable of working with large molecules. Disadvantages: the "blind tests" carried out by the "Cambridge Crystallographic Data Centre" are giving a 50% maximum success in the predictions. 2) with software based on DFT calculations: Advantages: good results Disadvantages: they are computationally very slow, so they are only used for very simple molecules compared with drug molecules. In addition, they have errors predicting van der Waals interactions and weak hydrogen bridges if not corrected empirically. 3) with software using ad hoc potentials for each molecule obtained from systematic exploration of the surface potential of intermolecular interactions: Advantages: efficient and faster. Disadvantages: some potentials should be calculated for each molecule studied, which are complex and slow, and is not general. The approach presented here is new and unique because the potential Pixel has never been used before for drawing polymorphic predictions and it has shown to present the advantages of all the alternatives combined. This is the first research group which has brought the potential Pixel to this level of calculation. The potential calculations and the applicability of the methode based on pixels have the same quality that the sophisticated ab initio based potential calculations. Besides, this is much faster than DFT (Functional-Based Theory)-based and ad hoc potentials ..NANOMYP posted this:
PolymP®-Active (Zn): Polymeric particles to reduce dentin hypersensitivityPolymP®-Active (Zn) is a breakthrough material that we have just patented for potentially treating dentin hypersensitivity. This new material (based on biocompatible polymeric particles) shows, among many others, the following key benefits: -Induces natural remineralization in few hours enhancing the precipitation of natural minerals that are not dissolved by saliva. -Low Mohs hardness: Do not result in dentin or enamel abrasion. -Fully occludes dentinal tubules enhancing surface nanohardness. -Possess antibacterial activity. -Inhibits dentin metalloproteinases, preventing the accelerated destruction of dentin. From a regulatory standpoint, the product could be developed as a cosmetic.
CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas posted this:
Polypeptides with antibacterial activityCSIC has developed several polypeptides with bactericidal activity from a phage lysin of Pseudomonas aeruginosa. These compounds are particularly active against Gram-negative bacteria, such as P. aeruginosa, Acinetobacter baumannii and Moraxella catarrhalis. The invention relates to these polypeptides for use in the treatment of diseases caused by bacteria, and preferably due to respiratory tract infections. Industrial partners from the pharmaceutical sector are being sought to collaborate through a patent licence agreement.
Javier Montiel BonmatíUniversidad de AlicanteJavier Montiel Bonmatí posted this:
Polyurethane adhesives with enhanced adhesion and mechanical properties due to the addition of very small amounts of graphenic carbon materialsPolyurethane adhesives are widely used in industry for bonding materials in the footwear, electronics, renewable energy, aeronautics, and construction industries, as well as in composite materials. However, they have limitations due to their mechanical properties and stiffness. Researchers at the university have developed a process to add different graphenic carbon materials to polyurethane adhesives in a very small amount (less than 0.1% by weight). In this way, an adhesive with improved thermal and mechanical properties (mainly toughness), and notably increased adhesion properties have been obtained. The resulting adhesives have been tested for verifying their new properties. These properties are ideal for use in high-performance applications, such as in the electronic components industry.
Universidad de Alicante
Cracow University of TechnologyCracow University of TechnologyBSUIR R&D Department posted this:
Portable cavitometer for measurement and control of the cavitation activity in high-power ultrasonic fields and hydrodynamic cavitation metersCan be used for optimization of ultrasonic technological processes, for detection of the presence and intensity of cavitation in hydraulic systems, for measurements of cavitation thresholds.
Pragmatec posted this:
Portable device for early detection of cervical cancer that provides immediate results using Biophotonics and Bioimpedance.This portable, non-invasive device scans different areas of cervical tissue, taking electrical measurements in different frequency ranges, optical measurements and wavelengths. The measurements are then processed by a configurable device or micro-controller in accordance with mathematical formulas obtained from multiple measurements taken from healthy and cancerous tissues.Three possible responses can be obtained immediately on the spot from the processing of the measurements: healthy tissue, cancerous tissue or the presence of human papilloma virus.
Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRIUniversidad de Alcalá-OTRI posted this:
Portable device to detect, diagnose and monitoring of tyrosinemiaA Spanish research Group from Analytical Chemistry, Physical Chemistry and Chemical Engineering Departments at University of Alcala (Spain) has designed and developed a metabolic rare disease sensor to diagnose and monitoring tyrosinemia in different biological fluidics (blood, plasma and urine) using very few amounts of the sample without any pretreatment. This device uses a non-invasive approach for and in situ monitoring of the disease, even by the own patient at home. The group is looking for companies to manufacturing a prototype, reaching licensing agreements or collaboration.
- Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRI
Universidad de Alcalá-OTRI posted this:
Portable device to measure the displacement maps on surfaces in the three spatial directionsA Spanish research group from the Department of Signal Theory and Communications of the University of Alcalá along with a Spanish research group from the Department of Mechanical and Mining Engineering of the University of Jaén has developed a portable optoelectronic device to measure the displacement of each surface element in an object when is subjected to deformation. In particular, the device allows obtaining maps of long range displacement (greater than mm) in dynamic regime (in real time). Thus this system is very useful in the experimental study of the materials’ mechanical properties, especially if they suffer large deformations at high speed. It is a computationally simpler alternative and more inexpensive than the digital mapping technique for 3D images which is currently the only one allowing such measures. The group seeks licensing agreements, collaborative and commercial agreements with technical assistance.
Meghan Meyer posted this:
Portable Infant Warmer- A foldable, manually transportable solution with low power requirements, ideal for under-resourced settings and emergency situations. - Combining body temperature regulation and full resuscitation capabilities, the device significantly increases newborn survivability in resource-constrained environments - Overcoming the limitations of heavy and expensive infant warmers, this solution provides a cost-effective and easily transportable option for both developing and developed countries
Other at Georgetown University
University of Huelva posted this:
Possibility of identifying nautical headlights at the distance that reaches the light if the headlights.An instrument is proposed for the automatic identification of nautical lights in river or maritime navigation, also applicable on mainland. The invention must address a specific problem consisting of optimizing the adjustment of the optical system for the different incoming light intensities.
Jagiellonian UniversityJagiellonian UniversityJagiellonian University posted this:
Potential new safe renewable source of energy - bioelectrode with lactobacillus rhamnosus bacteria biofilmThe subject of the offer is a method of formation of Lactobacillus rhamnosus bacteria biofilm on the metallic surface and the bioelectrode obtained in that manner.Development of suitable modifications of metallic electrodes’ surface allowed to use L. rhamnosus in the context of bioelectrochemical systems. This strain is safe, commonly used in the food, cosmetics and pharmaceutical industries. Bioelectrodes according to the inventive could be used in microbial fuel cells, microbial electrolytic cells and potentially for the construction of biosensors. The implementation of the invention will allow for obtaining a new, relatively cheap and easy to build renewable energy source, which will be neutral for human and the environment.- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Potyvirus viral detection kitCSIC and the Universitat Politècnica de València have developed a method for the detection and quantification of all species of the viral genus Potyvirus present in plant samples. The different species of the genus Potyvirus cause losses of up to 90% of production in crops of high economic interest, such as potato, maize or sugar cane. So far, the only way to identify that the crop was being attacked by a virus of the genus Potyvirus was to make specific detections for each species of the genus. With this new system it is possible to determine if in the samples coming from a culture there is presence of one of the 148 known species of the genus Potyvirus or of some unknown variant of these species. Companies in the agro-food sector interested in incorporating this kit for viral detection are being sought. An offer for Patent Licensing
University of Huelva posted this:
Power supply system controlled from internet for devices connected to a lanNowadays there are devices that allow the control of devices connected to a network from the own network. The classical method to access them from a different network is the redirection of the corresponding TCP or UDP connections to local networks from the border router. The redirection requires a high level of expertise in communications to be performed. Another strategy that is often used is the creation of VPN (virtual private network). This technique allows the control of access but does not allow connections to be discriminated or the management of power supply. The proposed system allows you to control the person and the moment to access as well as the free access. The modification of these constrains can be performed in the course of an access session. In addition, the system allows the control of power supply of the device you want access to. The interface is very friendly and does not require continuous changes in the configuration of the router. The system has a local database access control and validation can be delegated to other servers using protocol validation like LDAP, IMAP, POP3, etc.- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Power Switch for high radiation EnvironmentsCSIC through the Instituto de Microelectrónica de Barcelona - Centro Nacional de Microelectrónica, has developed a novel JFET (Junction Field-Effect Transistor) which is very suitable to be used in high-radiation-level environments such as Space, high-flying aircraft, particles accelerator or radio-medical equipment. Due to its particular configuration, the device presents very high radiation hardness. Industrial partners from the electronic industry focused on radiation detection are being sought to collaborate through a patent license agreement.
EPIC Semiconductors posted this:
Pre-Quantum exploration using Smart Dust in combating COVID-19A ‘Smart Dust’ is a battery-free, Energy Harvesting 'Sense-it-All' with Integrated Pre-Quantum Superposition Processor and AI that Communicates Wirelessly to the Cloud (RF-Free & Zero Power). A horizontal technology, it can also empower other industries Looking for partnership or research opportunity? Smart Dust with an integrated capillary system and markers will be a powerful tool in combating viruses & detecting pathogens.
- at EPIC SemiconductorsUniversidad de Cádiz posted this:
Pre-treatment of lignocellulosic biomass for the production of second-generation bioethanol• The action of the alkaline peroxide at moderate concentrations has been combined in one single stage. • The reaction times are short and the operating temperature is moderate. • The accessibility of the polysaccharides to the subsequent enzymatic attack is improved. • Hydrolysis yields of close to 100% are obtained. • Added value can be obtained from agricultural wastes rich in lignocellulose. • Low cost of implementation. • Simplicity of design.
Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC posted this:
Precast concrete floating platform to supportOff-shore deep sea wind turbines
- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
Precast concrete floating platform to support Off-shore deep sea wind turbinesA new system including the design of the platform and erection process has been developed to produce economical and high-reliable floating support to offshore wind turbines in deep sea waters. A prestressed concrete structure built in a dry-dock, which includes both the floater and the tower is towed to the final position, where it is erected in a simple operation. The nacelle and the turbine can be placed without using a high crane. Partners to further develop the system and/or to establish commercial agreements along with technical cooperation are sought. - CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Precision arm for fixing a surface antena in a sample in magnetic resonanceCSIC and Miguel Hernández University have developed an articulated device for precise and solid positioning of surface antennas and wires used in nuclear magnetic resonance imaging (MRI). The device improves the reliability and precision of MRI and allows for a total control of the procedure, therefore reducing errors or failures in data collecting and minimizing its possible unwanted effects. Industrial equipment manufacturers are being sought to collaborate through a patent licence agreement for the industrialization and commercialization of the device. An offer for Patent Licensing
IBIMA-Plataforma BionandIBIMA-Plataforma BionandCINBIO posted this:
Precursor compounds for providing retinoids of the vitamin A5 pathway and uses thereofThe invention relates to the field of retinoid X receptor (RXR) signalling and a novel vitamin A pathway called Vitamin A5 pathway. Compounds which are useful to provide (R) 9-cis-13,14-dihydro-retinoic acid an endogenous RXR ligand are claimed as well as their uses and method for preparation thereof. The inventors identified a series of compounds including members of an independent new vitamin A pathway (Vitamin A5), most notably 9-cis-13,14-dihydroretinol (9cDHROL), and which are precursors of the actual endogenous RXR ligand. They have also surprisingly found that these precursors produce an unexpectedly high increase of 9cDHRA in the brain and are useful vectors to target brain signaling of RXRs. The compounds of the invention are useful for pharmaceutical and nutritional uses.
Institut Català d'Investigació Química (ICIQ)Institut Català d'Investigació Química (ICIQ)Institut Català d'Investigació Química (ICIQ)Technology Transfer Office
Institut Català d'Investigació Química (ICIQ) posted this:
Precursors of linear polyacenes: entry door to new semi-conductor materialsA new strategy for the preparation of precursors of linear acenes has been developed. The developed acene precursors are hydrogenated acenes and are stable upon storage. They can be prepared in several synthetic steps using two catalytic key preparation steps. The precursors can be deposited onto surfaces and submitted to annealing to generate the linear acene. This strategy afforded the first-ever preparation of undecacene.
Fundación para la Investigación Biosanitaria de Andalucía Oriental (FIBAO)Fundación para la Investigación Biosanitaria de Andalucía Oriental (FIBAO)Fundación para la Investigación Biosanitaria de Andalucía Oriental (FIBAO)Technology Transfer Office
View ProfileFundación para la Investigación Biosanitaria de Andalucía Oriental (FIBAO) posted this:
Predict method of Pregnant Gestational ageDespite the great effort among all sectors of health, the rate of PD remains the "big problem" for obstetricians, neonatologists and other medical specialists, both the difficulties related to the care and complications of those born and their prognosis. long-term. Because PD, in addition to increasing perinatal morbidity and mortality, causes neurological damage and affects development in newborns, there is a great need to identify women at risk of preterm delivery and includes the mechanisms that culminate in PP. method that serves to predict, with clinical and analytical variables, the week of gestation in which delivery will occur.
Biomedical Research Center Sant Pau (IIB)Biomedical Research Center Sant Pau (IIB)Biomedical Research Center Sant Pau (IIB) posted this:
Predicting behavioural addictionsA computer-implemented method for predicting whether a subject is likely to develop Behavioural Addiction (BA). The method consists of a neurophysiologic measurement of the subject in response to incentive processing.
Yeda posted this:
Predicting Blood MetabolitesThe serum metabolome contains a plethora of biomarkers and causative agents of various diseases. They are known to be modulated by various genetic and environmental factors such as the gut microbiome, nutrition, and lifestyle. However, most of the serum metabolites and their determinants are still unknown. The group of Prof. Eran Segal characterized the serum metabolome of a well-phenotyped human cohort using mass spectrometry. Using this database, the team developed machine learning algorithms to predict metabolite levels in held-out individuals based on their host genetics, gut microbiome, clinical parameters, diet, lifestyle, and anthropometric measurements. The team developed a method to predict the serum metabolome non-invasively, based on the subject’s microbiome profile (using stool samples) or dietary habits. The method could be applied to predict diseases associated with specific blood metabolites (i.e., metabolic disease, cardiovascular disease, and kidney disease). It can also provide recommendations for dietary changes, probiotics, or antibiotics consumption to alter the blood metabolome and improve a subject’s health.
Yeda posted this:
Predicting Childhood ObesityChildhood obesity is a global health crisis, which holds extended complex health and psychological problems. Although an early diagnosis of children at risk for obesity could allow intervention and prevention, healthcare professionals have little guidance to identify individuals at risk. The current technology provides a method to identify individuals at high risk of developing childhood obesity before two years old, allowing early intervention and possible prevention of future obesity.
Yeda posted this:
Predicting Gestational Diabetes Mellitusdiabetes mellitus (GDM) is one of the most common complications of pregnancy, increasing the risk for short and long-term adverse events for both mother and offspring. Early intervention can reduce future complications, however, GDM is currently diagnosed only at late pregnancy stages. The group of Prof. Eran Segal developed a computational method that identifies women who are at high risk to develop GDM during early pregnancy stages based on electronic health records and a questionnaire. This can be applied as an early selective screening process, exempting women at low risk from unnecessary glucose tolerance tests, thus reducing costs and inconvenience.
LUCIA CORALNational Cancer Institute CRO AvianoLUCIA CORAL posted this:
Predictive Kit to identify patients non responding to platinum therapyPredictive Kit to identify patients non responding to platinum therapy. 10 gene signature as a predictive biomarker for platinum treatment against different cancer types. The invention consists in quantifying the expression of 10 genes from tumor cells to detect patients eligible for platinum treatment at higher risk of developing drug resistance and disease progression. Drugs such as cisplatin, oxaliplatin and carboplatin are used to treat various types of worldwide common cancer, but resistance is a frequent event. Patient stratification based on tumor gene expression profile allows to personalize treatment reducing side effects and costs.
Knowledge Tranfer Manager at National Cancer Institute CRO Aviano
Mark RichardsonNational Biofilms Innovation CentreMark RichardsonCEO at National Biofilms Innovation Centre
Mark Richardson posted this:
Predictive lab models of the human digestive and respiratory systems.Animal free, wet lab models capable of simulating the processes of digestion, mucus permeation and epithelial absorption through the mouth, stomach, small and large intestine
CEO at National Biofilms Innovation Centre
