Consejo Superior de Investigaciones Científicas

Oleuropein obtaining procedure: high purity antioxidant

Posted by Consejo Superior de Investigaciones CientíficasResponsive · Patents for licensing · Spain

Summary of the technology

CSIC has developed a reliable and effective method for obtaining oleuropein from olive leaf: comprising
a pretreatment that increases the concentration of oleuropein in the extracts over other known
methods and achieving this bioactive compound with a purity superior of 70%.

Industrial partners from the food and pharmaceutical industry are being sought to collaborate through
a patent licence agreement.

An offer for Patent Licensing

Consejo Superior de Investigaciones Científicas

Health promoting compound of natural origin

High purity oleuropein extracts from olive leaf Oleuropein is obtained from olive leaf by a quick and simple procedure that includes a pelletizing step of the raw material, providing better results in terms of the concentration of the bioactive compound extracted. The obtained extract can achieve a higher purity of 70% oleuropein, depending on the starting raw material and other factors.
Numerous studies have demonstrated that oleuropein has a wide range of pharmacological and health promoting properties including its antioxidant effect, anti-inflammatory, anti-atherogenic, anti-cancer, antiviral and antimicrobial.
Pre-clinical trials have shown that oleuropein exerts a protective action against cardiovascular and metabolic diseases.

Main innovations and advantages

· Obtaining of high purity natural bioactive compound · Valorization of olive grove residual biomass · Valorization of abundant byproduct from the olive oil industry · Pelletizing pretreatment process of the raw material improvesoutcomes · Application of the obtained oleuropein as a food supplement withhealth-promoting properties tested in pre-clinical trials · Application of the obtained oleuropein on cosmetic and pharmaceuticalindustries

Intellectual property status

Granted Patent
Spanish patent granted

Granted Patent
Spanish patent granted

Technology Owner

Consejo Superior de Investigaciones Científicas

Public Agency

Related keywords

  • Pharmaceutics
  • Pharmaceutical Products / Drugs
  • Agrofood Industry
  • Technologies for the food industry
  • Food Technology
  • Genetic Engineering / Molecular Biology
  • Health food
  • antioxidant
  • oleuropein

About Consejo Superior de Investigaciones Científicas

Public Agency from Spain

The Spanish National Research Council (in Spanish 'Consejo Superior de Investigaciones Científicas (CSIC)') is a government agency for basic and applied scientific research.

It is the largest public research organization in Spain, with presence in all the Autonomous Communities through 126 centers and 145 associated units.

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