Universidad de Alicante posted this:A decision support system for melanoma diagnosis.A Spanish Research Group has developed a system to help in the recognition of a melanoma through the visual characteristics of an image of the skin lesion. This system can be used as an automated way to decide the urgency to refer a patient to the dermatologist.
Fundació URV posted this:A robust breast cancer computer-aided diagnosis systemWe analyze breast cancer in mammographies, ultrasonographies, magnetic resonance imaging (MRI) and thermographies. Our analysis includes mass/normal breast tissue classification, benign/malignant tumor classification in mammograms and ultrasound images, tumor detection in thermograms, mammogram registration and analysis of the evolution of breast tumors. We also quantify and visualize the evolution of breast tumors in patients undergoing medical treatment. While the previous works mainly focus on analyzing one type of breast images, we implement a robust CAD system for detecting, classifying and studying the evolution of breast cancer. This CAD system analyzes breast cancer in several types of medical images. To implement our CAD system, we use computer vision, pattern recognition and machine learning methods. We also need to collect a large scale breast cancer dataset from hospitals. This dataset should include mammograms, ultrasound, thermograms and MRI images for the same patients. Our CAD gives accurate diagnosis results because it gathers information from different sources.
IMIM Institut Recerca Hospital del Mar posted this:A TREATMENT FOR TRIPLE NEGATIVE BREAST CANCERTriple negative breast cancers are tipically associated with por prognosis, due to aggressive tumor phenotype(s), only partial response to chemoterapy and present lack of clinically established targeted therapies and respresent the focus of increasing interest at the clinical, biological and epidemiological level, as disclosed in Podo et al., Triple –negative breast cancer: Present challenges and new perspectives, Mol. Oncol., 2010, 4, 209-229. There is, thus, a particular need for new active agents suitable for breast cancer treatment, and in particular need for triple negative breast cancers.
JPT Peptide Technologies posted this:Custom Peptide SynthesisJPT Peptide Technologies has a substantial, long-standing expertise in custom peptide synthesis services, providing custom peptides with highest quality for even complex or unusual peptide sequences. If you would like to order a quality peptide synthesis service using regulated processes, choose JPT! Furthermore, our peptide synthesis service has a very high success rate (over 99%) as JPT has developed the know-how to choose and optimize the appropriate synthesis method for each peptide. We go the extra mile to get your peptides done!
DIT Hothouse posted this:U-Learn: A Training Model for Breast Ultrasound imagingU-learn is a training and learning model for radiographers and registrars for training in breast ultrasound imaging. The model assesses the performance of a trainee registrar before, during, and after training using the ultrasound imaging phantom which is a realistic representation of the breast.
DIT Hothouse posted this:Cervassist: Cervical Cancer AnalyserCurrently, cytologists are needed to examine smear samples under a microscope to visually assess the shape, size and stain pattern and determine if abnormal cells are present which could indicate cervical cancer. Alternatively, automated image analysis is used to determine nuclear density but cytologists are still needed to determine the presence of abnormal cells. The current processes are prone to human error and misdiagnosis can be up to 60%. They are also time consuming and costly.Sample user interface for spectral acquisition and classification. Researchers at DIT have invented an easy to use, low cost, automated analyser that uses a pre-defined library of known cell signatures and a proprietary classification algorithm to detect abnormal cells with an accuracy of 99%. The analyser can be used with a regular microscope, an image analyser or as a point-of-care system with results displayed using an intuitive user interface. The image and the classification can be saved in digital format, stored in a national database, and sent to the medical team or experts worldwide
Universidad de Alcalá-OTRI posted this:Anticancer activity of Ru (II) Arene complexes with oxime ligands.Spanish research group from the department of Inorganic Chemistry the University of Alcala, together with a Moroccan research group from the University of Abdelmalek Essaadi, have developed a process to synthesize metal complexes with anticancer properties, which can be used for cancer treatment and prevention. The group is looking for companies working in the pharmaceutical and biomedical sector to achieve license, collaborative or commercial agreements with technical assistance.
IMIM Institut Recerca Hospital del Mar posted this:A prognostic and predictive serum biomarker in Small Cell Lung CancerPeripheral blood and its components (serum, plasma, and circulating cells) is an easily accessible fluid. An ELISA-based system that exploit circulating protein biomarkers found in this medium is more convenient to the patient compared to a more invasive lung biopsy. The researchers have found that high levels of serum hepatocyte growth factor (sHGF) protein in patients with SCLC shows clearly predicted for shortened survival and an incremental risk for death. HGF is a natural ligand for the oncogenic epithelial transition factor (c-Met) transmembrane tyrosine kinase receptor and serum HGF could be predictive of individual responses to new anti-cancer drugs: the Met inhibitors. The Met inhibitors are targeted therapies against c-Met receptor that are currently in development for the treatment of other neoplasms and are planned to be evaluated in SCLC. Therefore, a biomarker of prediction of response to these new Met inhibitors would be crucial for correct selection of patients for the clinical trials. Incorrect selection through other biomarkers in NSCLC has leaded to lack of benefit from these drugs in already performed phase 3 clinical trials, stressing the relevance of correct patient selection
Pragmatec posted this:Portable device for early detection of cervical cancer that provides immediate results using Biophotonics and Bioimpedance.This portable, non-invasive device scans different areas of cervical tissue, taking electrical measurements in different frequency ranges, optical measurements and wavelengths. The measurements are then processed by a configurable device or micro-controller in accordance with mathematical formulas obtained from multiple measurements taken from healthy and cancerous tissues.Three possible responses can be obtained immediately on the spot from the processing of the measurements: healthy tissue, cancerous tissue or the presence of human papilloma virus.
Universidad de Alcalá-OTRI posted this:Semipurified fraction of Ganoderma lucidum with antitumour activity (cytotoxic activity and apoptotic cells in murine lymphoma and human leukemia)A fraction of compounds obtained from Ganoderma lucidum has been described. This fraction is active on murine lymphoma DA-1 cells and human leukemia NB4 cells. This fraction induced DNA fragmentation, changes in cell membrane and cell death. The innovation lies on the antitumor activity, the source of such compounds (the mushroom Ganoderma lucidum grown in stablished conditions developed in our lab).
Small and Medium Enterprise
Creative Biogene posted this:Human SSTR2-FLAG Stable Cell Line-CHOSomatostatin receptors are activated by somatostatin secreted from nerve and endocrine cells. The Somatostatin Receptors (SSTRs) are expressed in a tissue-specific manner and involved in the regulation of secretion of insulin, glucagon and growth hormone as well as cell growth induced by neuronal excitation in both the central and peripheral nervous systems. Aberrent expression of somatostatin receptors is known in a large number of human tumours. SSTR2 is expressed in highest levels in the stomach, jejunum, cerebrum, thyroid and kidney.
Small and Medium Enterprise
Creative Animodel posted this:Animal Model Products & ServicesAs a world leader in custom transgenic animal model, Creative Animodel has years of experience serving hundreds of clients across six continents. Our full-service model has enabled medical and academic researchers to receive over 1,000 successful and unique gene targeted animal model lines. Creative Animodel's clients return regularly for the experience, service and results that push research forward.
RAMOT at Tel Aviv University Ltd. posted this:Macrolid Induced Correction of Premature Stop Codons: A novel Treatment for Colorectal CancerAn antibiotic of the Macrolid family was demonstrated as a new treatment for colorectal cancer and other genetic human diseases that arise from pre-mature stop codons in important coding sequences. Project ID : 10-2007-109
RAMOT at Tel Aviv University Ltd. posted this:A New Application for Vitamin DCalcitriol (1,25-dihydroxyvitamin D3), the main hormonally active metabolite of vitamin D was found, in vitro, together with some of its synthetic analogs to have the potential to reduce the damage inflicted to normal tissue by accepted anti-cancer therapy. Project ID : 10-2007-101