Molecular design Technology Technology Offers

Covid-19 Innovation Challenges by Innoget posted this:

Viral RNA-dependent RNA Polymerases Viral RNA-dependent RNA Polymerases (RdRPs) Targeted Library (1259 compounds) with predicted activity against viral RdRPs is offered. It has been carefully designed using machine learning (artificial neural networks and Bayesian statistics

Viral RNA-dependent RNA Polymerases

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

Viral RNA-dependent RNA Polymerases Viral RNA-dependent RNA Polymerases (RdRPs) Targeted Library (1259 compounds) with predicted activity against viral RdRPs is offered. It has been carefully designed using machine learning (artificial neural networks and Bayesian statistics

Viral RNA-dependent RNA Polymerases

CNIC (TTO) posted this:
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)

iSuRe-Cre as a new genetic tool to modify and understand gene function Most analysis of gene function in biomedical research relies on the use of Cre-lox technology. Since its introduction in 1994, this technology has revolutionized biomedical science because it allows scientists to eliminate or activate the function of any gene in any cell type in the mouse. Because the Cre-loxP recombination event is invisible, genetic and fluorescent reporters have been developed to track Cre activity, so that cells reaching a certain threshold of Cre activity are labeled. However, the main problem is that often the Cre activity level is insufficient to fully recombine and eliminate expression of the target gene, generating uncertainty about whether the desired genetic modification has been achieved. CNIC researchers have developed a method that increases the efficiency and reliability of the analysis of Cre-dependent gene function. Moreover, the use of this genetic tool permits the induction of multiple genetic deletions in the same cell, to allow the study of functional genetic interactions.

iSuRe-Cre as a new genetic tool to modify and understand gene function

Covid-19 Innovation Challenges by Innoget posted this:

Expertise in molecular biology either experimentally or computationally The Institut de Biotecnologia i de Biomedicina (IBB) was created in 1970 as a research institute of the Universitat Autònoma de Barcelona (UAB) to promote fundamental biological research. In the year 2000, the focus of research evolved towards the Biotechnology and Biomedicine fields, with the aim of advancing scientific findings into translational results. At present, the Institute hosts 18 research groups organised into 3 programmes and working in 7 areas of expertise: • Bioinformatics • Cellular Biology • Structural Biology • Genomics • Immunology • Microbiology • Proteomics. This multidisciplinary character, one of the most relevant characteristics of the IBB, allows for a broad approach to biological problems, both basic and applied. The IBB is also highly engaged in academic training at the undergraduate and postgraduate levels.

Expertise in molecular biology either experimentally or computationally

Ivan Rodriguez Rosello posted this:
Licensing Manager at Universidad de Alicante

Novel bioadhesive for wound closure in animals or humans The Adhesion and Adhesives Laboratory research group has developed a new biomaterial for use as adhesive or tissue sealant applicable to both animals and humans. This invention solves the disadvantages of the adhesives known so far presenting optimal properties such as biocompatibility with living tissues, high adhesive capacity, adaptable to the tissue of the wound being bond, absence of toxicity and tissue regeneration properties. The group is looking for companies interested in acquiring this technology for commercial exploitation.

Novel bioadhesive for wound closure in animals or humans

Consejo Superior de Investigaciones Científicas posted this:

Molecular Method that radically improves the diagnosis of Hereditary hemorrhagic telangiectasia (HHT)Molecular Method that radically improves the diagnosis of Hereditary hemorrhagic telangiectasia (HHT). The Granada University, Health and Progress Foundation, and the CSIC have developed a diagnostic molecular system for the HHT by getting a simple liquid biopsy from the patient. Industrial partners are being sought to collaborate through a patent license agreement to use this molecular diagnostic system with the possibility of informatics support.

Molecular Method that radically improves the diagnosis of Hereditary hemorrhagic telangiectasia (HHT)

Nadiia Kachaput posted this:
Project coordinator at Otava Research Institute

Synthesis of dual-targeted inhibitors of HDAC1 and mTOR for cancer therapy Our offer is a chemical optimization service - synthesis of two-target specific set of pyrazolo[3,4-d]pyrimidine derivatives as dual-targeted inhibitors of HDAC1 and mTOR. We will synthesize these novel analogs only upon your request.

Radoslaw Rudz posted this:
Other at Centre Technology Transfer CITTRU

In vitro culture medium for cells, tissues, and organs of amphibians The subject of the offer is a specialized medium for the in vitro culture of cells, tissues, and organs of amphibians. Thanks to the unique composition of active substances and refined their concentrations to the requirements of amphibian cells, the use of medium enables long-term culture as well as a high level of cell proliferation and reduction of cell mortality.

In vitro culture medium for cells, tissues, and organs of amphibians

Mansour Esmaeil Zaei posted this:
Technology Broker at Technology Transfer Centre, University of Warsaw (UOTT UW)

The Centre of New Technologies of the University of Warsaw (CeNT UW)The Centre of New Technologies of the University of Warsaw (CeNT UW) is an interdisciplinary research institute dedicated to the understanding of biological, chemical and physical phenomena. Our scientists tackle fundamental scientific problems, collaborate and apply the attained knowledge to the industry. CeNT UW provides a truly international outlook, establishes a perfect work environment for both young and established researchers, and promotes the education of PhD students. CeNT UW obtained the scientific rating of “A” (very-good level) in a heterogeneous group on the basis of a comprehensive assessment of scientific and R&D activities of scientific units made by the Ministry of Science and Higher Education for the period of 2013-2016. The institute was established by Resolution No. 362 of the Warsaw University Senate on April 20, 2011, as an organizational unit of the University of Warsaw.

The Centre of New Technologies of the University of Warsaw (CeNT UW)

UACOOPERA University of Aveiro posted this:
Technology Transfer Office at uacoopera

Magnetic nanoparticles for selective enrichment of proteins in complex mixtures New method for preparing ion chelating magnetic nanoparticles, which allow selective protein enrichment, namely metalloproteases (MMPs) and His-tagged proteins, from complex mixtures.

Magnetic nanoparticles for selective enrichment of proteins in complex mixtures

Universidad de Alcalá-OTRI posted this:

Carbosilane dendrons functionalized with fatty acids: Formation of micelles and uses in biomedicine as antiviral, antibacterial, antiprionic, antimicrobial and drug transporters.The research group of the University of Alcalá in «Dendrimers for biomedical applications» presents the following invention that refers to the formation of dendrons of carbosilane structure that have in their periphery preferably anionic or cationic groups and in the focal point fatty acids or derivatives of these. Its main field of application is in biomedicine, as non-viral transport agents, as drug transporters, to elaborate a drug, as antimicrobial, antiviral or antipyretic agents. In the environmental sector we also find its application as biocides for water treatment. The group seeks to reach license agreements, collaboration or commercial agreements with technical assistance with companies from the sector of Health, Pharma and Environment.

Universidad de Alcalá-OTRI posted this:

Carbosilane dendrimers and their use as antivirals The research group in "Dendrimers for Biomedical Applications" of the University of Alcalá presents these highly branched macromolecules synthesized from a polyfunctional nucleus, of carbosilane structure and functionalized in its periphery with anionic groups that give the macromolecule a negative net charge. In addition, the invention relates to the use of the dendrimers as an antimicrobial and the process for obtaining them. The group seeks to reach collaboration agreements, licensing or commercial agreements with technical assistance, with companies in the biotechnology, pharmaceutical and biomedicine sectors in general.

Universidad de Alcalá-OTRI posted this:

Carbosilane dendrimers with polyphenolic groups. Uses as antioxidants and anticancer.The "Dendrimer for biomedical applications Research Group" at Alcalá University presents dendritic macromolecules with skeleton of carbosilane nature that contain in their structure polyphenolic groups (GPF). These compounds are powerful antioxidants and free radical scavengers, as well as anticancer agents, with application in sectors such as food, cosmetics and pharmaceutical industry. The invention provides a process for its procurance and uses.

Universidad de Alcalá-OTRI posted this:

New therapeutic agents for the treatment of inflammatory disorders The research group, « Heterobetaines », from Alcalá University in colaboration with the research group « Hipersensibility to medicines and inmmunitary innate response » form IDI La Paz, present a new generation of inhibitors of alfa tumoral necrosis factor (TNF-α) production, useful to prevent and / or treat inflamatory diseases. The group is looking for technical cooperation or license agreements with pharmaceutical companies, research centers or diagnostic and treatment against inflammatory diseases research institutions.

New therapeutic agents for the treatment of inflammatory disorders

DIT Hothouse posted this:

Raman Spectroscopy for Molecule Detection and Analysis Raman is an advanced spectroscopic technique with applications in disease diagnosis, identification of biochemical markers, and drug discovery.

Raman Spectroscopy for Molecule Detection and Analysis

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