Synthetic Biology Technology Offers

Maria João Cardoso posted this:
Science and Technology Manager at UATEC - Unidade de Transferência de Tecnologia

Electrospinning system for large-scale manufacturing of aligned 3D fiber matrices Continuous electrospinning system and process for production of thick 3D matrices of aligned polymeric fibers. The matrices obtained with this technology can have aligned polymeric fibers with several patterns along the matrix’s thickness, which size depends solely on the number of layers of deposited fibers, on the fibers thickness and the compaction degree between layers. In this way, the present technology can be applied in varied areas, for the manufacture of products or structures, at the nanometric scale, that depend on high surface areas, such as biotechnology, pharmaceutics and tissue engineering.

Electrospinning system for large-scale manufacturing of aligned 3D fiber matrices

Maria João Cardoso posted this:
Science and Technology Manager at UATEC - Unidade de Transferência de Tecnologia

Separation of nucleic acids using chromatographic matrices functionalized with ionic liquids Novel multimodal chromatographic supports prepared by functionalizing matrices with ionic liquids, allowing the separation of RNA and DNA in a single chromatographic step with high selectivity, robustness and reproducibility. In comparison to other commercially available supports, a higher dynamic binding capacity for RNA was obtained.

Separation of nucleic acids using chromatographic matrices functionalized with ionic liquids

UATEC - Unidade de Transferência de Tecnologia posted this:

Ohmic heating reactor for chemical synthesis, the method and its applications In ohmic heating electrical energy is dissipated in heat with a very high efficiency (electrodes in contact with the reaction medium), resulting in fast and uniform heating and in the increase of charged species movement. As in the case of the heating with microwave radiation, electrical energy is transformed into thermal energy. However, on contrary of heating with microwave radiation (penetration depth of microwave radiation in absorbing media is limited) the penetration depth is virtually unlimited and the extent of heating is regulated only by the spatial uniformity of electrical conductivity throughout the reaction medium and the time spent in the ohmic reactor. Thus, the direct scaling of the ohmic heating for the pilot or industrial scale shouldn’t have the limitations presented by microwave radiation heating. It is also possible to reduce reaction times and increase the energy efficiency of chemical reactions

Universidad de Alcalá-OTRI posted this:

Carbosilane dendritic compounds homo and heterofunctionalized A Spanish research group from the Department of Organic and Inorganic Chemistry of Alcala University has developed a highly branched macromolecules called dendrimers or dendrons, with carbosilane structure and functionalized on its periphery with anionic or cationic groups, providing the macromolecule a net negative or positive charge respectively. The invention also concerns the dendrimers’ procurement process and their biomedical applications, particularly as carriers of drugs or nucleic acids (such ODN, siRNA, dsRNA or DNA), or as therapeutic agents with antiviral or antibacterial activity. The group is looking for companies in the biomedical sector to reach licensing agreements, collaboration and commercial agreements with technical assistance.

Maria João Cardoso posted this:
Science and Technology Manager at UATEC - Unidade de Transferência de Tecnologia

Production method of a new recombinant collagenase for collagens digestion Method for obtaining collagenase with high collagenolytic activity, through a process based on recombinant DNA technology. This new process enables collagenase purification e isolation through a simple and economical procedure, obtaining an active enzyme with remarkable storage stability.

Production method of a new recombinant collagenase for collagens digestion