Cellular and Molecular Biology Technology Technology Offers

Ivan Rodriguez Rosello posted this:
Licensing Manager at Universidad de Alicante

Antibacterial alternative to antibiotics, with high specificity against Escherichia coli The "Molecular Microbiology" research group at the University of Alicante has modified several phage proteins (Poll-N and UK-C) that have high specificity against Escherichia coli (E. coli), but not against other Gram-negative (G-) bacteria. For these reasons, their use as a specific antimicrobial against E. coli is potentially interesting, especially in the case of contaminated food, cosmetics or water. It would also be useful in the treatment of diseases (infections) caused by E. coli. The presence of a histidine tail attached to the phage proteins not only facilitates their purification but also improves lysis efficiency without the need of cell permeabilization treatments. Companies interested in the commercial exploitation of the technology through license agreements and/or technical cooperation are sought.

Antibacterial alternative to antibiotics, with high specificity against Escherichia coli

UACOOPERA University of Aveiro posted this:
Technology Transfer Office at uacoopera

MAGNETIC NANOPARTICLES FOR TEMPERATURE-CONTROLED MOLECULE AND CELL SEPARATION AND DETECTION Coated and functionalized magnetic nanoparticles for e.g. detection and separation of DNA and RNA, protein purification, cell separation and immunoassays, con-trolled by temperature. Contrary to state-of-art mag-netic nanoparticles presently used for separation, which always present a certain degree of aggregation, the present technology proposes nanoparticles with tem-perature-controlled magnetic response. The magnetic response of these new nanoparticles is suppressed at higher temperatures (tunable between 40°C and 100°C) avoiding aggregation and is enhanced at lower temperatures promoting separation.

MAGNETIC NANOPARTICLES FOR TEMPERATURE-CONTROLED MOLECULE AND CELL SEPARATION AND DETECTION

Consejo Superior de Investigaciones Científicas posted this:

Identification of particles and/or cells in suspension using a mechano-optical system CSIC has developed a sample analyzing system that can identify particles and/or biological cells in aqueous suspension or in physiological medium. The system allows simultaneously measuring the mass and light scattering of the particles in suspension in real time. This technology has been used to distinguish different cell lines, making it useful for diagnosing diseases. Industrial partners manufacturers of lab equipment are sought to collaborate through a patent license agreement. An offer for Patent Licensing

Identification of particles and/or cells in suspension using a mechano-optical system

Yissum - Research Development Company of the Hebrew University posted this:

Novel Naturally Occurring Compounds for Treating Cystic Fibrosis Cannabis project Derivatives of cannabinoids have an antimicrobial and anti biofilm effect on pseudomonas and candida which are major ethological pathogenic factors in CF Project ID : 6-2019-6720

Consejo Superior de Investigaciones Científicas posted this:

Transphagocytic T cells as anti cancer immunotherapy Transphagocytic T cells as anti cancer immunotherapy CSIC´s research group, in collaboration with scientists from the Centre of Molecular Biology “Severo Ochoa” (CBMSO-CSIC), the Autónoma University of Madrid and the Health Research Institute of the “La Princesa” University Hospital, developed a new method for anti-cancer immunotherapy based on transphagocytic lymphocytes (tiCD4+ T cells) Companies interested in a patent license or investors for creation of a start-up are being sought. An offer for Patent Licensing

Transphagocytic T cells as anti cancer immunotherapy

Consejo Superior de Investigaciones Científicas posted this:

Biocompatible self-generating cell stimulator CSIC through the Instituto de Microelectrónica de Barcelona - Centro Nacional de Microelectrónica, has developed a device based on nanogenerators for electrical cells stimulation without the need of electrodes or bulky devices. The device is biocompatible and, among its multiple applications, is able to actuate in medical prostheses as enhancer of cellular growth and proliferation, which permits an early lesion recovery (such as a fracture or wound). Industrial partners dedicated to the development of medical devices for cells stimulation, in particular, focused onto therapeutic treatments of non-healing wounds, are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing

Biocompatible self-generating cell stimulator

Consejo Superior de Investigaciones Científicas posted this:

Kits for cell culture based on hydrogel coatings CSIC and Complutense University of Madrid have developed new kits for cell culture based on cytocompatible hydrogels coated onto stiff substrates. Due to the excellent adhesion of the hydrogel to these substrates is possible to have mechanically robust platforms, easy to handle as required in a cellular biology laboratory. These new kits have been successfully tested showing an excellent cellular proliferation on the surface of the hydrogel. Besides, this technology allows the detachment of a cell monolayer without the need of chemical or biological agents preserving the viability of cell harvesting. Industrial partners from the biotechnology with expertise in cell culture are being sought to collaborate through a patent license agreement. An offer for Patent Licensing

Kits for cell culture based on hydrogel coatings

IDIBELL posted this:

Exosomal miRNAs in seminal plasma as non-invasive markers of prostate cancer diagnosis Identified miRNAs, from the semen samples, could be used as non-invasive biomarkers that contribute in the diagnosis/prognosis of malignant prostate cancer.

Exosomal miRNAs in seminal plasma as non-invasive markers of prostate cancer diagnosis

Consejo Superior de Investigaciones Científicas posted this:

Biocompatible self-generating cell stimulator CSIC through the Instituto de Microelectrónica de Barcelona - Centro Nacional de Microelectrónica, has developed a device based on nanogenerators for electrical cells stimulation without the need of electrodes or bulky devices. The device is biocompatible and, among its multiple applications, is able to actuate in medical prostheses as an enhancer of cellular growth and proliferation, which permits an early lesion recovery (such as a fracture or wound). Industrial partners dedicated to the development of medical devices for cells stimulation, in particular, focused onto therapeutic treatments of non-healing wounds, are being sought to collaborate through a patent license agreement.

Biocompatible self-generating cell stimulator

Consejo Superior de Investigaciones Científicas posted this:

Molecular Method that radically improves the diagnosis of Hereditary hemorrhagic telangiectasia (HHT)Molecular Method that radically improves the diagnosis of Hereditary hemorrhagic telangiectasia (HHT). The Granada University, Health and Progress Foundation, and the CSIC have developed a diagnostic molecular system for the HHT by getting a simple liquid biopsy from the patient. Industrial partners are being sought to collaborate through a patent license agreement to use this molecular diagnostic system with the possibility of informatics support.

Molecular Method that radically improves the diagnosis of Hereditary hemorrhagic telangiectasia (HHT)

Nadiia Kachaput posted this:
Innovation Manager at Ukrainian Laboratories

Synthesis of dual-targeted inhibitors of HDAC1 and mTOR for cancer therapy Our offer is a chemical optimization service - synthesis of two-target specific set of pyrazolo[3,4-d]pyrimidine derivatives as dual-targeted inhibitors of HDAC1 and mTOR. We will synthesize these novel analogs only upon your request.

Radoslaw Rudz posted this:
Licensing Manager at Centre Technology Transfer CITTRU

Hydrogel hybrid material for the reconstruction of bone defects The subject of the offer is an injectable, hydrogel hybrid material that can be used to construct a bioactive cell scaffold of a minimal invasivity. This scaffold may be located in place of a bone defect thus enabling reconstruction of bone tissue. Application: in tissue engineering for the reconstruction of orthopedic and dental bone defects.

Hydrogel hybrid material for the reconstruction of bone defects

Ukrainian Laboratories posted this:

Synthesis of Styryl-phenyl-ureas as Dual-targeted Inhibitors of PD-L1 and VEGFR-2 We offer the chemical optimization service - synthesis of targets-specific set of styryl-phenyl-urea derivatives as dual-targeted inhibitors of PD-L1 and VEGFR-2.

Synthesis of Styryl-phenyl-ureas as Dual-targeted Inhibitors of PD-L1 and VEGFR-2

Ukrainian Laboratories posted this:

Synthesis of 1-(Aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole Derivatives as Antiprotozoal Agents Our company offers the chemical optimization service - synthesis of a unique 1-(aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole derivatives for your biological projects, related to developing of antiprotozoal drugs.

Synthesis of 1-(Aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole Derivatives as Antiprotozoal Agents

Radoslaw Rudz posted this:
Licensing Manager at Centre Technology Transfer CITTRU

In vitro culture medium for cells, tissues, and organs of amphibians The subject of the offer is a specialized medium for the in vitro culture of cells, tissues, and organs of amphibians. Thanks to the unique composition of active substances and refined their concentrations to the requirements of amphibian cells, the use of medium enables long-term culture as well as a high level of cell proliferation and reduction of cell mortality.

In vitro culture medium for cells, tissues, and organs of amphibians

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