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CSIC - Consejo Superior de Investigaciones Científicas posted this:
Biogenesis on-demand for the production of carotenoids and phytonutrientsCSIC and the Center for Research in Agricultural Genomics have developed a biotechnological method for the biofortification in carotenoids and other phytonutrients of green tissues. The method is based on the controlled induction of chromoplasts. The mechanism could be applied to the development of novel functional foods or bio factories for a variety of industries. Industrial partners are being sought to collaborate through a patent license agreement.CSIC - Consejo Superior de Investigaciones Científicas posted this:
Biohybrid catalyst with coper nanoparticlesCSIC has developed a novel hybrid material consisting on a protein matrix and nanoparticles of different copper species. The effect of the combination is an enhancement of the peroxidase activity of the material which leads to degradation of organic molecules at short times. It also shows an interesting catalase-like activity. Industrial partners from the chemical or biochemical industry are being sought to collaborate through a patent license agreement An offer for Patent LicensingUniversity of Luxembourg posted this:
Bioimaging Platform - Luxembourg Centre for Systems BiomedicineThe LCSB Bioimaging Platform (bip) provides access to and support for a broad palette of advanced microscopy and flow cytometry instruments, enabling researchers to perform studies from the tissue level and down to sub-cellular scales.Biogas & Gases Technologies posted this:
Biolimp-MPdry. Technology for biogas cleaningBiogas is a dirty gas. Therefore, it requires a previous cleaning to be used as biofuel. There are many components to be removing, among them, water vapor, siloxane, halogenated hydrocarbons and H2S, all of them, affects the good performance of the CHP system. The Biolimp-MPdry technology is a multipropose technology that allows the biogas cleaning with a very lower costs and high performace yield.Yeda posted this:
Biologic Drug for prevention and treatment of COVID-19Combat against COVID-19 is still ongoing worldwide. Despite the great advancements in the realm of vaccine development, there is still a great need for efficient medications to treat the disease, especially in vulnerable populations (such as elderly people and subjects with background illnesses). A common strategy in drug development against COVID?19 is inhibiting the binding of the viral Spike protein to the cellular ACE2 receptor, which facilitates the virus's entrance to the cells. While many attempts focus on blocking the viral Spike protein, this strategy is sensitive to viral mutations, making it less efficient. The teams of Profs. Schreiber and Rudich developed a stable protein that binds the ACE2 receptor at ultra?high affinity (pM), effectively blocking viral infection without affecting the natural activity of the receptor. The protein can be administered through inhalation and can be combined with other potential anti-COVID-19 drugs such as interferon-?.Universidad de Alicante posted this:
Biological control of pests: breeding protocol for Sphaerophoria rueppellii for use in biological control of aphidsMembers of CIBIO Research Institute, led by Professor Maria Angeles Marcos Garcia, head of the Associated Unit to CSIC, have developed a method to raise the dipterans predator Sphaerophoria rueppellii. This insect is known for its efficiency and high specificity predatory sirphid being more suitable as biological control agent against agricultural pests from aphids in a Mediterranean climate crops. The use of this natural enemy for biological control of pests will reduce pesticide use in both agricultural crops and in urban gardens. Have been optimized environmental conditions for breeding, such as diet (both immature and adult stages) to ensure a higher reproductive potential and higher rates of survival. The group is looking for companies interested in acquiring the technology for commercial exploitation. Innovative aspects 1- The only species of industrially produced sirphid (Episyphus balteatus) does not effectively control aphid pests in Mediterranean cultures, this is why the selection of another species of sirphid to act as a viable alternative in the field Mediterranean was needed. The novelty of this specie is that and in most cases of biological control, using species that are commercially available, or not part of the fauna, in this case, we have managed to breed the species in field trials, proved to have the greatest potential for control. 2- This is the first time that this predator specie is bred in the laboratory and maintain continuously during successive generations breeding in significant amounts from individuals. 3- Due to the invention has been developed by a consolidated research group, it will be applied a Quality Control (under the rules of the International Organisation for Biological and Integrated Control), to ensure the viability and product qualityJagiellonian University posted this:
Biological method of reducing excessive growth of filamentous bacteria in activated sludge in wastewater treatment plantsThe subject of the offer is a biological method of reducing excessive growth of filamentous bacteria in activated sludge in wastewater treatment plants. The invention uses organisms naturally occurring in the activated sludge - rotifers, which eliminate filamentous bacteria that cause bulking of activated sludge - one of the most prevailing and most serious problems in sewage treatment plantsIMDEA Water Institute posted this:
Biology and microbiology laboratoryIn our Biology and Microbiology laboratory we provide surface and groundwater analysis services in order to: • Support water quality surveillance initiatives through standardised national and international methods, in accordance with the Water Framework Directive (WFD 2000/60/EC) and Groundwater Directive (GWD2006/118/EC). • Monitor cyanobacteria blooms and their toxins in surface water and develop technological solutions for the elimination of cyanotoxins in water treatment.University of Alberta, Technology Transfer Services posted this:
Biomarkers and new adjuvant treatment for HIV-Associated Neurocognitive DisordersPotential to predict the development of HIV-associated neurocognitive disorder (HAND). Potentially treat HIV patients with HAND or at high risk of HAND development. Creates the possibility to monitor disease/treatment progress for HIV-HAND.Universidad de Granada posted this:
Biomarkers for non-invasive detection and classifform-control form-control ication of prostate cancerThree new biomarkers for the prognosis, stratification and cancer monitoring have been identified: PCA3, MRC2, and S100A4. These biomarkers could be detected by non-invasive methods, such as liquid biopsy, and be used as a component for kits and devices with the same purpose.Universidad de Granada posted this:
Biomarkers for the diagnosis of pediatric B-cell acute lymphoblastic leukemia (B-ALL).The present invention highlights the identification of two new biomarkers for the diagnosis of pediatric B-cell acute lymphoblastic leukemia (B-ALL). In this sense, the analysis of the expression of the lncRNA and mRNA pair makes it possible to recognize and evaluate patients who develop the disease. Consequently, its use is support in therapeutic decision-making in patients with B-ALL.CNIC (TTO)Spanish National Center for Cardiovascular Research (CNIC)
CNIC (TTO)Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)
View ProfileCNIC (TTO) posted this:
Biomarkers for the early detection of subclinical atherosclerosisOne of the main problems of atherosclerosis disease is that it is diagnosed too late. Primary prevention is currently based on the evaluation of modifiable risk factors according to standardized recommendations. There is a need to find new biomarkers for subclinical atherosclerosis, which are independent of traditional cardiovascular risk factors and scores. CNIC, UAM and IIS-FJD researchers have discovered a panel of proteins, which are accumulated in the atheroma plaques themselves even in their earliest stages of formation. Moreover, the plasma abundance levels of these proteins could be used to predict the presence of subclinical atherosclerosis. Diagnosis/biotech companies are sought for a license agreement.
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)IBIMA-Plataforma Bionand posted this:
Biomarkers to predict response to treatment in metastatic melanoma patientsThis technology is a panel of genetic biomarkers that can predict or predict the response of patients with metastatic melanoma who carry BRAF mutations to treatment with BRAF and MEK inhibitors. ▪ Allow the development of a diagnostic kit or device. ▪ Thanks to the prediction of prognosis, patients with worse prognosis can be followed more closely. ▪ This panel allows a further step towards personalized medicine, enabling more patient-focused and efficient clinical care.Subramani Naidu posted this:
Biomelanin synthesised from FungiWe have synthesised eumelanin from fungi at low cost. Currently cuttlefish, octopus is used for the same. Applications include UV protection and hair dye. Future potential includes fuel cell and electric car cathode
Promoter at QuickGun LifeScienceUACOOPERA University of Aveiro posted this:
BioMEMs - BioMicroElectroMechanical system device for bone regenerationBioMicroElectroMechanical System devices (BioMEMs) targeted to the promotion of bone regeneration by means of coating a biomedical metallic substrate with a functionalized ferroelectric/piezoelectric biocompatible oxide layer or with a functionalized piezoelectric biocompatible and biodegradable polymeric layer.
Technology Transfer Office at uacooperaUniversidad de Alicante posted this:
Biometric identification system based on eye blinkingThe Optics and Vision Sciences research group at the University of Alicante has developed a method for biometric authentication by recognizing the blinking of a subject. The method consists of studying and characterizing the changes in the intensity of diffused light during the blinking process. Those changes are used to classify the blinks using different algorithms. A subject can then be identified according to the parameters recorded. This method allows the authentication of subjects by means of a non-contact procedure, and even unconsciously. Commercial or built-in on mobile devices video cameras or webcams can be used for its application provided that the video is recorded at rates higher than 150 frames per second (fps). We are looking for companies interested in the commercial exploitation of this technology as well as in adapting it for the development of related projects.Research Transfer Office University of GranadaUniversity of Granada (OTRI)
Research Transfer Office University of GranadaTechnology Transfer Advisor at University of Granada (OTRI)
View ProfileResearch Transfer Office University of Granada posted this:
Biomimetic magnetic nanoparticles for its use in biotechnological applicationsThe present invention provides a composition which contains nanoparticles of magnetite made in presence of magnetosome proteins expressed as recombinant. These nanoparticles are biocompatibles, have a negative charge at physiological pH and a size higher tan 30nm, considered in the range of the singular magnetic domain, for different uses in the field of biotechnology, as well as for its use for for drug administration for the treatment of cancer.
Technology Transfer Advisor at University of Granada (OTRI)Unismart - University of Padua Foundation posted this:
Biopesticides for the treatment of wine pathogensThis patent covers the synthetic analogues of the natural trichogin peptide GA IV and their use as biopesticides against Plasmopara viticola, Botrytis cinerea, Penicillium italicum, Penicillium digitatum, Penicillium expansum, Fusarium graminearum e Pyricularia oryzae.CSIR posted this:
Bioplastic technologyThe CSIR has developed a bioplastic technology for producing 100% biodegradable and compostable plastic. The technology enables single-use plastic products that, when they end up in landfills, bio-degrade within 180 days. The bioplastic products, when combined with organic waste, can turn into compost within 90 days, leaving no toxic residues. Bioplastics are a relatively new field within the South African plastics industry. As a result, landfills overflow with plastic bags and products from the household waste removal process. The CSIR’s bioplastic is made from plant-based materials to ensure that the disposed plastic waste in landfills is transformed from the biobased polymer into organic fertiliser. The development is a significant milestone for the CSIR in working towards environmental sustainability and a green economy for South Africa. “Our bioplastic technology is based on the use of biopolymers and agricultural waste by-products such as starch, cellulose and glycerol. Through smart use of additives, we have created unique formulations to modify the properties through a melt-processing technique. This has resulted in pellets which can be blown into films for carrier bags, kitchen waste bags, mulch films and packaging films, as well as rigid cutlery products,” says CSIR senior researcher Dr Sudhakar Muniyasamy. The technology can help those players in the agricultural, medical and hospitality industries who are looking for green methods of packaging. In this market, approximately 90% of packaging products are typically produced from petroleum-based chemicals which are often disposed of in natural environments after single or short-term use. “Our technology has been validated at an industrial manufacturing facility, and the pilot scale-testing for the production of the pellets and industrial-scale conversion process has been done for a specific product line,” adds Muniyasamy. As part of the commercialisation process, the CSIR is now working towards licensing the technology.UACOOPERA University of Aveiro posted this:
Biopolymer based micro- and nano-particles for industrial and environmental applicationsMethod for preparing hybrid materials based on biopolymer and silica, in the form of spherical particles with uniform size and smaller than 1 micrometer (µm), for several applications in environmental and industrial areas.
Technology Transfer Office at uacooperauacoopera posted this:
Biopolymer based micro- and nanoparticlesA group of researchers from a Portuguese university developed a method for preparing new hybrid materials based on biopolymer and silica, in the form of spherical particles with uniform size and smaller than 1 micrometer for a number of applications in environmental and industrial areas. The method is also effective for coating nanoparticles of variable nature, with a thin shell (tens of nanometers) with composition identical to the hybrids. The materials have been successfully tested in the removal of chemical species in water at laboratory scale, in particular in the removal of organic pollutants dyes and pharmaceutical compounds. Other applications are being considered. The University looks for companies working in the environmental, pharmaceutical or biotechnology areas, or companies in the area of materials for licensing and / or future collaboration in developing new formulations and testing new applications.Universitat Politècnica de Catalunya - UPC posted this:
Biopolymer-containing calcium phosphate foam for bone regenerationA new calcium phosphate foam with open pore macroporosity useful for bone regeneration and drug release has been patented and developed.Universitat Politècnica de Catalunya - UPC posted this:
Biopolymer-containing calcium phosphate foam for bone regenerationThe Challenge Hidroxyapatyte is a natural mineral found in teeth and bones. It is commonly used as a filler to regenerate bone or as a coating to promote bone growth. The application of calcium phosphate cements, which can form hydoxyapatite, in the treatment of bone defects, begun more than two decades ago and many formulations have been developed so far. The ideal bone replacing cement should be osteoconductive and osteoinductive, to stimulate bone regeneration. Moreover, it should be resorbable and gradually replaced by newly formed bone. Although most of the developed calcium phosphate cements are more resorbable than sintered hydroxypatite ceramics, they still show relatively slow resorption kinetics and in many cases the cement remains stable in the implanted site during years. The absence of interconnected macropores is indeed a limiting factor to achieve resorption. If the designed material has macropores, cells can colonize it and the access of osteoclasts is facilitated increasing the rate of healing of the bone defect.Universidad de Alcalá-OTRI posted this:
Bioremediation strategy in situ for the precipitation and immobilization of uranium and other toxic elements in contaminated soils.A research group from the Geology Department of the University of Alcalá is developing a technology to study the role of the oxidation-reduction processes of humics in the reduction of uranium and other toxic metals in contaminated soils to determine whether stimulating the activity of humic-reducing and oxidizing microbial communities in contaminated soils can be an effective strategy for the in situ immobilization of uranium and other toxic metals. The group is looking for technical cooperation projects with companies.Laijo Jose posted this:
Bioresorbable polymer composite for bone-soft tissue fixation.An advanced and cost effective bioresorbable, biocompatible polymer composite for bone soft tissue fixation has been developed, and their use in preparing different orthopedic devices that serves the purpose of fixation of soft tissue injuries and low-load bearing bone fractures. The use of the given bioresorbable polymer composite in orthopedic devices is an attempt to replace the traditional metallic implants and making it accessible to masses at affordable prices, and therefore overcome the limitations of currently available bioresorbable orthopedic devices in the market. The technology produces a novel bioresorbable, biocompatible polymer composite for bone soft tissue fixation. The polymer composite biomaterial is composed of bioresorbable polymer such as poly-ε-caprolactone (PCL), natural fiber silk fibroin and an osteoconductive component like Magnesium oxide (MgO) in nanoparticle form and it can be used to prepare different orthopedic devices. The silk fiber of 20% and MgO nanoparticles in concentration of 10% were mixed together with PCL as base polymer in twin-screw extruder to produce composite orthopedic biomaterial. The newly developed bone screw is having a design with screw head shape, thread-tip design, thread profile and volume. It is found that millions of screws are being used for bone or soft-tissue fixations per year and the need of such fixations devices in world orthopedic market is ever-growing. The cost effective bioresorbable composite device thus made is also having wider clinical applications with its higher bioactivity (biomineralization), biocompatibility, infection resistivity and proper bone remodeling properties.
Manager-Tech Transfer at Centre For Future (CFF)University of Waterloo posted this:
Biosensor for detection of heavy metalsWaterloo researchers have developed a novel metal sensing platform based on DNAzymes (also known as deoxyribozymes or catalytic DNA). They incorporated a phosphorothioate modification in DNA and performed extensive in vitro selections to generate the most optimal sequence for detecting heavy metals. By making a phosphorothioate (PS) modification (adding a Sulphur group) to a previously known RNA-cleaving DNAzyme (Ce13d), the substrate cleavage site shifts the activity from being dependent on lanthanide to thiophilic metals such as Cd2+, Hg2+ and Pb2+. Thus, the catalytic domain of the DNAzyme catalyzes heavy metal-dependent cleavage of the substrate cleavage site. By incorporating this PS modification, a sensor array was prepared to detect each one of the metals with high sensitivity (limit of detection = 0.1 nM Pb2+, 4.8 nM Cd2+ and 2.0 nM Hg2+.Germans Trias i Pujol Health Sciences Research Institute posted this:
Biosignatures for ulcerative colitisCurrently, the glucocorticoids are the first-line of treatment for of moderate-to-severe flare-ups. However, up to 40% of patients do not have an adequate response. Mechanisms of steroid-refractoriness in UC remains unknown. In addition, corticosteroid failure impair the effectiveness of rescue therapies.CSIC - Consejo Superior de Investigaciones Científicas posted this:
Biotechnological production of 11α hydroxylated steroids using recombinant bacteria.CSIC has developed a procedure for the biotechnological production of 11α hydroxylated steroids by generating and subsequent use of recombinant bacteria. These recombinant bacteria allow to perform microbial biotransformation processes that result in 11αhydroxylated steroid compounds from raw materials such as phytosterols and intermediate products efficiently and economically. These compounds have numerous applications in pharmacology. Companies are sought for implementing and commercializing the new technology under patent license agreement. An offer for Patent Licensing