Consejo Superior de Investigaciones Científicas

New system to modulate the degree of silencing of a gene of interest in plants

Posted by Consejo Superior de Investigaciones CientíficasResponsive · Patents for licensing · Spain

Summary of the technology

CSIC and UPV have developed a system that allows modulating the degree of silencing of any gene that is of interest in plants. Until now, the technologies used to regulate gene expression in plants only allowed to induce a high degree of silencing, but the level of silencing had not been regulated.

This new system, through the use of small artificial RNAs (sRNAs), modulates the degree to which gene silencing occurs. This technology has a special interest in the case of wanting to silence a lethal gene and, for example, when the gene that is silenced is regulating the flowering time.

Companies interested in patent licensing are sought for the development.

Consejo Superior de Investigaciones Científicas

Fine modulation of the degree of silencing

Obtaining Arabidopsis plants with different flowering times using different degrees of gene silencing This system, through several approximations, allows a fine modulation of the degree of silencing of the desired gene. Producing a silencing in the desired degree, in an efficient and reliable way.

A clear example of its applicability is in the case that the gene of interest is regulating the flowering of the plant, such as the FT gene. Through this system we can generate varieties that flourish in different seasons and thus ensure production throughout the year.

Until now it was not possible to modulate gene expression using sRNAs, opening up a whole new range of possibilities for the development of crops of agronomic interest.

Main innovations and advantages

· Modulator system that allows fine regulation of gene expression.
· There is no system known to date that allows to regulate geneexpression through the use of sRNAs.
· It allows the gene silencing of lethal genes.
· Possibility of regulating the gene expression of genes that affect thecharacteristics of crops of economic interest

Intellectual property status

Granted Patent
Priority patent application filed suitable for international extension

Granted Patent
Priority patent application filed suitable for international extension

Technology Owner

Consejo Superior de Investigaciones Científicas

Public Agency

Related keywords

  • Electronics, IT and Telecomms
  • Agriculture and Marine Resources
  • Agriculture
  • Agrofood Industry
  • Biological Sciences
  • Biology / Biotechnology
  • Gene - DNA Therapy
  • Genetic Engineering Technology
  • Genome Research
  • Biocontrol
  • Precision agriculture
  • Seed coating
  • Plant health
  • Plant and animal health
  • Agricultural genetic engineering applications
  • Genetic Engineering / Molecular Biology
  • Industrial genetic engineering applications
  • Microbiology Market
  • gene silencing

About Consejo Superior de Investigaciones Científicas

Public Agency from Spain

The Spanish National Research Council (in Spanish 'Consejo Superior de Investigaciones Científicas (CSIC)') is a government agency for basic and applied scientific research.

It is the largest public research organization in Spain, with presence in all the Autonomous Communities through 126 centers and 145 associated units.

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