New system to modulate the degree of silencing of a gene of interest in plants

Summary of the technology

CSIC and UPV have developed a system that allows modulating the degree
of silencing of any gene that
is of interest in plants. Until now, the technologies used to regulate gene expression in plants only
allowed to induce a high degree of silencing, but the level of silencing had not been regulated.
This new system, through the use of small artificial RNAs (sRNAs), modulates the degree to which gene
silencing occurs. This technology has a special interest in the case of wanting to silence a lethal gene
and, for example, when the gene that is silenced is regulating the flowering time.

Companies interested in patent licensing are sought for the development.
An offer for Patent Licensing

CSIC - Consejo Superior de Investigaciones Científicas

Fine modulation of the degree of silencing


Obtaining Arabidopsis plants with different flowering times using different degrees of gene silencing This system, through several approximations, allows a fine modulation of the degree of silencing of the desired gene. Producing a silencing in the desired degree, in an efficient and reliable way.
A clear example of its applicability is in the case that the gene of interest is regulating the flowering of the plant, such as the FT gene. Through this system we can generate varieties that flourish in different seasons and thus ensure production throughout the year.
Until now it was not possible to modulate gene expression using sRNAs, opening up a whole new range of possibilities for the development of crops of agronomic interest.

Main innovations and advantages


· Modulator system that allows fine regulation of gene expression.
· There is no system known to date that allows to regulate geneexpression through the use of sRNAs.
· It allows the gene silencing of lethal genes.
· Possibility of regulating the gene expression of genes that affect thecharacteristics of crops of economic interest

Intellectual property status

  • Granted Patent
  • Patent application number :-

  • Granted Patent
  • Patent application number :-

Related Keywords

  • Electronics, IT and Telecomms

About CSIC - Consejo Superior de Investigaciones Científicas

The Spanish National Research Council (in Spanish 'Consejo Superior de Investigaciones Científicas (CSIC)') is a government agency for basic and applied scientific research.

It is the largest public research organization in Spain, with presence in all the Autonomous Communities through 126 centers and 145 associated units.

CSIC - Consejo Superior de Investigaciones Científicas

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