Technology Offers Site map description
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Itzel Saldivar posted this:
DRONA: Software requirements management tool for Enterprise ArchitectThe tool is built as an add-in for Enterprise Architect - designed and tested for (1) defining, modelling, and optimizing technical requirements, (2) requirements authoring support, (3) reconciliation between requirements models, and (4) automated generation of full deliverables, as well as (5) acceptance criteria written as Gherkin test scenarios.
Tech Transfer Officer at SnT
Brunel University LondonBrunel University LondonBrunel University London posted this:
DRooTES: Double Rooted Trailing Edge Serrations for quiet bladesAerofoil blade designs with double rooted serrations that reduce trailing edge noise to the maximum through destructive interference. They can be attached to existing blades so are particularly suitable for retrofitting to larger blades, such as wind turbines. They are however applicable to a wide range of blades moving in air and water, for example turbines, fans, rotary wings and fixed wings. The scale of application ranges from small drones (small blades operating at high speeds) to large wind turbines (large blades operating at slower speeds).
Germans Trias i Pujol Health Sciences Research InstituteGermans Trias i Pujol Health Sciences Research InstituteGermans Trias i Pujol Health Sciences Research Institute posted this:
Drug Delivery PlatformColonoscopic procedures have become widespread in recent years since colorectal cancer (CRC) and inflammatory bowel disease (IBD) have become prevalent disorders. Their use has expanded as diagnostic and therapeutic tools in both elective and emergency situations. Colorectal cancer (CRC) is the most common cancer in both men and women. In the case of polypectomy, as in the case of surgery, the stabilization of the primary tumors could allow the use of optimizing chemotherapy and therefore an overall improvement in the treatment of the disease.
Larisa SheloukhovaKyoto UniversityLarisa Sheloukhova posted this:
Drug discovery for Charcot-Marie-Tooth Disease Using Patient-Derived iPS Cell LinesCharcot-Marie-Tooth disease (CMT) is one of the most common rare diseases affecting approximately 1 in 2,500 - 5,000 people, or 3 million people in total worldwide. It is characterized by progressive peripheral neuropathy. The disease appears in two main forms: demyelination of the myelin sheath, which is formed by Schwann cells wrapping around the axon, or degeneration of the axon itself. There are various types of CMT caused by mutations in different genes. CMT1A, caused by a duplication of the PMP22 gene, is the most common demyelinating type, affecting ~50% of individuals with CMT. CMT2A, caused by mutations in the mitofusin-2 (MFN2) gene, is the most common axonal defect type. Gene therapies and small molecules are under development for different CMT types, however, there are currently no available treatments or cures for CMT patients. SCAD is a spin-off from Kyoto University that specializes in the development of disease models using patient-derived iPS cell lines for CMT1A and 2A, conducting drug discovery research to clarify pathology and explore therapeutic drugs, as well as pursuing cell therapy for neuropathies using pluripotent stem cells.
Global Tech Commercialization at Kyoto University
CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas posted this:
Drug repurposing against pneumococcus and other Streptococcus genus speciesCSIC has developed a patent for the use of 7 drugs as novel antimicrobials that display bactericidal activity against Streptococcus pneumoniae (pneumococcus), acting on therapeutic targets not considered in the usual treatments for this pathogen. Industrial partners are sought which are interested in patent licensing for the development of the mentioned drugs as antibacterials targeting the Streptococcus genus and that open up new ways for treatments against these pathogens and for combating current antibiotic resistance issues.
IDIBELL posted this:
Drug repurposing for lupus nephritis therapyDrug repurposing for lupus nephritis therapy. Compound X, already approved for human use in other medical indications, administered orally, can be repurposed for lupus nephritis treatment. The principal goal of compound X therapy in lupus nephritis is to normalize renal function or, at least, to prevent the progressive loss of renal function. ✓ Less side effects than the standard of care ✓ Already approved for human in other medical indications (Reprofiling) ✓ Market with 1 approval in last 50 years
NDI Foundation posted this:
DSP - digital signal processor of new generationThe project offers new assembler, that’s High level assembler and New core of processor’s architecture. The invention is new generation device for signals processing. The proposed assembly language is based on a formulaic recording of mathematical operations, which greatly improves the process of creating programs and their debugging. Program language maximally adapted to the processing of data arrays, tables, etc. Temporary programming costs are reduced repeatedly and commensurate with programming in C, and in some cases even less, and resulted with efficient assembly code. Developed prototype of core DSP implemented and successfully tested. Complete set for work with the processor and software: simulator, compiler, debugger system tests, library routines etc. Prepared patent applications, including patent applications for DSP core architecture and instruction set, as well as some of the functional blocks. The developed core can be a base for a number of circuits intended for different applications. The proposed architecture of the core is not the final possible product. Currently the architecture of the microcontroller and the next version of DSP core with a flexible architecture and programming language are under development.
University of Granada (OTRI)University of Granada (OTRI)University of Granada (OTRI) posted this:
Dual Probes for Flow Cytometry and Mass CytometryResearchers of the University of Granada have developed probes based on nanoparticles, both fluorescent and functionalized with metals, which act as dual probes, and can be used for both flow cytometry (FACS –Fluorescent-Activated Cell Sorting) and mass cytometry (CyTOF -Cytometry by Time-Of-Flight-). The probes can be used for bar coding of living cells or carrying out in vivo studies of different cell lineages through cell co-cultures as well as the activation of drug precursors through cytoplasmic catalysis of organometallic reactions inside living cells.
Unitat de Valorització de la URVFundació URVUnitat de Valorització de la URV posted this:
Dual-curing system for advanced processing in 3d printingVat photopolymerization 3D printing offers high resolution, surface quality, and geometric precision, benefiting industries like automotive, aerospace, medical, and R&D. However, challenges in scaling and material performance persist. A dual-curing acrylic-epoxy system addresses these issues, enabling low shrinkage, high mechanical properties, and post-processing flexibility, offering a scalable, robust solution for demanding structural applications.
Licensing Manager at Fundació URV
Georgetown UniversityGeorgetown UniversityGeorgetown University posted this:
Dual-Electrode in situ Infrared Spectroscopy for Fuel Cells and Batteries- Utilizes dual-electrode in situ/operando infrared spectroscopy enabling spectroscopic access to both the anodic and cathodic reactions of a fuel cell or a rechargeable battery during operation. - Allows for the measurements of chemical species in anodic reactions and chemical processes of forming and deteriorating solid-electrolyte interphase (SEI) through use of ATR-IRS measurements. - Enhances understanding of operational chemistry of fuel cells and rechargeable batteries, potentially improving their performance and efficiency.
Chicagoland Automation posted this:
Dual/Triple Sump pump controller with optional bluetooth or Wifi connectivityDual sumpump controller with redundant level sensing and % level showing. Optional Bluetooth/ Wifi connectivity for mobile app or IOT. One primary and one secondary back up pump, Automatic testing of back up pump when water level rise rate is slow. Pump start/stop will vary within programmed range and depending on water level rise to minimize start / stop cycles. Option for third pump.
University Hospital Hradec KrálovéUniversity Hospital Hradec KrálovéUniversity Hospital Hradec Králové posted this:
Dually Acting Tacrine Derivatives for Treatment of Neurodegenerative Disorders - A dually-acting compounds with neuropsychopharmacological and drug-like properties with potential therapeutic useNeurodegenerative disorders (ND) accounts the vast majority of age related dementias characterized by progressive cognitive decline of higher mental functions. The research devoted to this field uncovered a pathomechanism of complex multietiology which cannot be addressed by hitting one target. Motivated by currently available treatment against ND involving the inhibitors of acetylcholinesterase (AChE) and N-methyl-D-aspartate receptor (NMDAR), administered also in combination, we developed dually-acting compounds based on 1,2,3,4-tetrahydro-9-aminoacridine (tacrine) structure and confirmed their neuropsychopharmacological and drug-like properties for potential therapeutic use. Only a few compounds have been established for the treatment of Alzheimer’s disease. For instance, FDA and EMEA have approved three cholinesterase inhibitors, one NMDA-receptor antagonist – memantine and one disease-modifying immunotherapy – aducanumab, for Alzheimer’s disease (AD). Here we offer a combination of both effect in a single molecule. To date there are many other drugs undergoing clinical trials in AD, having various mechanism of action (vaccines against amyloid beta, against Tau protein, antiinflammation drugs) but none of them seems to reach the registration in a short term. Novel molecules represent a new way how to cope with the multiple pathogenic factors of ND. Based on our observations, we suppose that these compounds are able to hit additional targets relevant to ND and thus succeed in overcoming the multifactorial pathogenesis. While tacrine (approved for AD treatment in 1993) was withdrawn from the market due to its hepatotoxicity and other side effects in 2013, our compounds were prepared to avoid this hepatotoxic effect as we demonstrated in in vitro studies. Since these compounds have also been found acting as GluN2B selective NMDAR antagonists, they are therefore believed to hold strong therapeutic potential in the treatment of other disorders – e.g. ischemic damage, chronic pain and depression. Authors would like to thank the grant of Ministry of Education, Youth and Sports of the Czech Republic (project ERDF no. CZ.02.1.01/0.0/0.0/18_069/0010054). 1. https://pubmed.ncbi.nlm.nih.gov/33892271/ 2. https://www.sciencedirect.com/science/article/abs/pii/S0006295221000563?dgcid=rss_sd_all 3. https://www.tandfonline.com/doi/abs/10.1080/01480545.2019.1566350?journalCode=idct20&
Dirección de Transferencia Tecnológica (DIT) Universidad Adolfo IbáñezUniversidad Adolfo IbáñezDirección de Transferencia Tecnológica (DIT) Universidad Adolfo IbáñezAgente de Innovación at Universidad Adolfo Ibáñez
View ProfileDirección de Transferencia Tecnológica (DIT) Universidad Adolfo Ibáñez posted this:
Durable Cement Coatings for Marine Constructions that Promote BiodiversityThe construction of underwater and coastal infrastructure, such as ports, breakwaters, and marine platforms, in natural marine habitats like reefs, estuaries, and mangroves disrupts hydrodynamic flows and alters sedimentary conditions. This leads to biodiversity loss and a decline in the quality of marine habitats. The technology offers modular slabs made of bio-enhanced concrete that mimic natural habitats, restore marine biodiversity, and withstand harsh marine conditions.
Agente de Innovación at Universidad Adolfo Ibáñez
Helen Xu posted this:
Durable QR barcode tag for LPG cylinder trackingWe successfully developed permanent barcode tags for LPG gas cylinders,it will work together with gas cylinder tracking software system. Which use corrosion resistant metal as matrix and integrate barcode information with ceramic glaze. The barcodes are corrosion-resistant and aging-resistant,which corresponds to the long life time and hostile working environment of gas cylinders.The chemical stability,corrosion-resistance,abrasion-resistance and temperature-resistance of glaze are very reliable.So when we integrate barcode information with glaze,we can protect barcode information from aging,corrosion,abrasion and high temperature while using barcodes in hostile working environment. The special barcode labels produced by Xiangkang have competitive prices and are being used by more than 3000 gas filling stations around the country.In the recent ten years,we have sold 70 millions.There is no doubt that the quality and life time of our barcode tags can satisfy the real usage of gas cylinders.
R&D Manager at LPG cylinder tracking
Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC posted this:
Dynamic control device for optimization and reduction of energy consumption in lighting of closed spacesA new methodology for the dynamic control of lighting in closed spaces has been patented and developed. The new device can be easily implemented in buildings and allows energy savings up to 85%. Partners to further develop the system and/or to establish commercial agreements along with technical cooperation are sought.
Max-Planck-Innovation GmbHMax-Planck-Innovation GmbHMax-Planck-Innovation GmbH posted this:
Dynamic control of three-dimensional light distributions through wavefront engineering: hardware and software systemEngineering light distributions in a three-dimensional volume to achieve selective illumination profiles is an instrumental task shared by many optical and microscopy techniques. The optimization of the light distribution can lead to significant enhancement of relevant performance figures and ultimately to the extension of the instrument or experimental protocol capabilities1,2,3,4,5. Targeted illumination profiles can be used either to mechanically interact with molecules at nanometer precision, as in an optical tweezer application, or to optically induce a change in the conformational state of molecules. Technology enabling selective control of light distributions has found an ideal match in the field of optogenetics, enabling high resolution light-based control of neuron activity. This technique is rapidly developing, and was awarded as method of the year 2010 by Nature Methods and was named as one of the breakthroughs of the decade by Science Magazine. The precision and power of optogenetic approaches are limited by the degree of spatio-temporal control in the delivery of light. Using wavefront engineering, a very precise light field distribution can be generated in a three-dimensional volume. This enables neuroscientists to selectively target specific sets of neurons in vivo for activation, to explore neural circuits and connectivity. This is a cutting edge technique, which is only starting to reach the market, and would be a desired add- on module to many microscopes.
PhD Isabel Gavilanes-Perez (RTTP)Spanish National Research CouncilPhD Isabel Gavilanes-Perez (RTTP)Open Innovation Manager at Spanish National Research Council
View ProfilePhD Isabel Gavilanes-Perez (RTTP) posted this:
Dynamic Pupil for ophthalmological applicationsResearchers from the Spanish National Research Council (CSIC) and the Catalan Institute of Nanoscience and Nanotechnology (ICN2-BIST) have recently developed a self‐regulating iris based on light‐actuated broadband absorber metamaterial. Manufacturing companies of contact lenses and/or ocular prosthesis are being sought to collaborate and/or exploit the existing know how through a patent license agreement.
Open Innovation Manager at Spanish National Research Council
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Dynamic Pupil for ophthalmological applicationsResearchers from the Spanish National Research Council (CSIC) and the Catalan Institute of Nanoscience and Nanotechnology (ICN2) have recently developed a self‐‐regulating iris based on light‐‐actuated broadband absorber metamaterial. Manufacturing companies of contact lenses and/or ocular prosthesis are being sought to collaborate and/or exploit the existing know how through a patent license agreement.
University of WaterlooUniversity of WaterlooUniversity of Waterloo posted this:
Dynamic Visual Acuity (VA) testBackground The global eye testing equipment market was valued at USD $2.64 billion in 2017 and is expected to reach $3.91 billion by 2025, registering a CAGR of 5.0% from 2018 to 2025. Significant increase in the incidence of eye-related disorders across the world has played a major role in driving the growth of eye testing equipment market. Visual acuity (VA) is a measure of the ability of the eye to distinguish shapes and the details of objects at a given distance. VA is influenced by many factors including the eye itself and environmental influences. The eye media (primarily the cornea and lens) are responsible focusing light on the retina and modulating VA. Any interruption of this optical pathway can lead to reduced VA. For instance, if the media do not focus the incoming light on the retina, but instead focus it in front of the retina (short-sightedness), or behind it (long-sightedness), or if one focus point on the retina is not attained (astigmatism) VA will be reduced and shapes and details will appear blurry. In addition, damage to the eye media, the retina or the optic nerve can also lead to reduced VA.
Mitsu YamamotoJapan Technology Group, Inc.Mitsu Yamamoto posted this:
Dynamically-stable omnidirectional electric vehicleWe would like to propose a technology for dynamically-stable omnidirectional electric vehicle that vehicle body is always kept in upright position and consequently provides larger stability margin while driving. This technology from the research team at the Tokyo University of Science offers a technology of mechanism which is potential applicable for an innovative electric wheel chair or personal vehicle as well as a next-generation autonomous mobile robot or an automatic guided vehicle. The research team are currently willing to seek collaboration opportunity for further development.
Business Development Manager at Japan Technology Group, Inc.
E
Yeda posted this:
Early Detection and Treatment of Myeloid Leukemiamalignancies such as AML and MDS are usually aggressive and have a low overall survival rate. Recent studies demonstrated that specific mutations in hematopoietic stem cells occur years before the disease is diagnosed in individuals at high risk of developing myeloid malignancies. Therefore, there is a need to prevent disease development in those individuals. The group of Prof. Liran Shlush found that inhibition of a specific error-prone DNA repair mechanism (MMEJ) could reduce the likelihood to develop future myeloid malignancies in high-risk individuals.
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Early Warning System for Anaerobic Digesters The CSIC and University Pablo de Olavide have developed a system for warning possible failure of the anaerobic digestion process carried out in a digester, using a microbial fuel cell connected to the digester by recirculation. This system is called Previous Destabilization Alarm for Anaerobic Digesters (PDAL). Companies interested in the license of the patent are searched for commercial exploitation.
Covid-19 Innovation Challenges by InnogetCovid-19 Innovation Challenges by InnogetCovid-19 Innovation Challenges by Innoget posted this:
Early warning system for detecting deterioration in post intensive care patientsIn the UK 28% of deaths in patients treated on an Intensive Care Unit (ICU) occur after the patients return to the general ward. These patients often suffer late developing complications after initial successful treatment in the ICU. There is usually a period of deterioration when a patient shows some signs of developing a complication. PICRAM (Post Intensive Care Risk Adjusted Monitoring) is a system that watches over the electronic records of the vital signs of patients after discharge from an ICU. It analyses the information to estimate the likelihood that a patient will suffer a complication in the next 24-48 hours. Patients most at risk of complications can then be identified and specialist nurses sent to start treatment early to the patients who need them most. The early detection of deterioration provided by PICRAM can save lives and reduce treatment costs.
- University of WaterlooUniversity of Waterloo
University of Waterloo posted this:
EasyPlan project management systemBackground Managing construction projects within strict deadlines and limited budgets is a huge challenge and many projects experience cost overruns and delays. For contractors to compete nationally and internationally in the multi-billion dollar construction industry, they need tools to efficiently manage project resources, increase productivity, meet constraints, and bring projects to profitability. Existing project management software does not provide a level of data analysis granularity to provide decision support for optimizing operations, automate progress tracking, and identify cost-effective corrective actions to keep projects on track.
University of Porto posted this:
Eco-friendly phytosomes for the delivery of naturally occurring bioactive ingredients of interest for pharmaceutical, cosmetic and food industriesThe invention describes a green phytosome-based delivery system for an eco-friendly and safe delivery of bioactive ingredients, especially natural occurring bioactive compounds. These phytosomes are obtained through eco-friendly, organic solvent-free methodologies and find application in pharmaceuticals, cosmetics, and food products.
IMDEA Water Institute posted this:
Ecological assessment of groundwater and groundwater dependent ecosystemsAn integrated management of groundwater resources requires a complete monitoring of biological, ecological and physical-chemical water properties in order to enhance our understanding on the ecosystem services they provide. IMDEA Water offers environmental services and fauna survey in groundwater (GW) and groundwater dependent ecosystems (GDEs) (i.e. the hyporheic zone of rivers, wetlands) for the groundwater resource sector. In order to ensure an adequate quality of groundwater for urban and rural consumption and considering the protection of aquatic resources to accomplish the directives regulations concerning water resources (Water Framework Directive, WFD 2000/60/EC, Directive on Environmental Quality, DEC 2008/105/EC and Groundwater Directive, GWD 2006/118/EC), we offer our integrated environmental consulting service on ecological assessment of GW and GDEs using a combination of traditional and innovative techniques for monitoring, evaluation and ecological analysis of GW biotic communities. We provide cost effective project solutions and outstanding client relations by delivering scientifically rigorous surveys on groundwater ecosystems.
Universidad de AlicanteUniversidad de AlicanteUniversidad de Alicante posted this:
Ecological concretes and mortarsA multidisciplinary public-private research consortium has developed a simple and innovative process to transform submerged arc welding slag waste into activated materials (geopolymers) that can be used as environmentally friendly substitutes for Portland cement to manufacture concrete or mortar-based construction materials. These new materials are characterised by low production costs, are environmentally friendly, sustainable, do not generate waste in their production process, and have excellent physico-chemical properties. Companies interested in acquiring this technology for its commercial exploitation are sought.
IMDEA Water Institute posted this:
Economic analysis of water resources managementThe main lines of research of the group are: •Water management in areas vulnerable to extreme weather events: drought risk and water scarcity. •Tools and methods for assessing potential climate change impacts, costs & benefits, and risks & opportunities. •Link between science (i.e. water economics) and policymaking (i.e. EU Freshwater Policy). •Hydroeconomic analysis of water investments. •Economic analysis of biophysical flows of ecosystem services. •Groundwater management.
