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IMIM Institut Recerca Hospital del MarIMIM Institut Recerca Hospital del MarIMIM Institut Recerca Hospital del Mar posted this:
New method for the determination of the risk of atypical fractures in patients treated with bone remodelling inhibitors.Up to date there is not any technology for detecting the risk to suffer atypical fractures related to long-term treatment with bone remodelling inhibitors. The invention will be of usefulness for individualize treatments in patients treated with bone remodelling inhibitors by detecting the individual risk of suffering atypical fractures. The invention is planned to be included into an in-vitro diagnostic tool for the atypical fracture, which will be included into standard disease management protocols and therefore used routinely by physicians prior to and after the prescription of bone remodelling drugs and further osteoporosis drugs. Osteoporosis is a progressive bone disease with a characteristic decrease in bone mass and density which can lead to an increased risk of fracture. There are two types of osteoporosis: •Type 1: most common in women after menopause, named postmenopausal osteoporosis •Type 2: Senile osteoporosis, occurs mostly after age of 75 years and has equally effect in women and in men Based on the WHO diagnostic criteria, approximately 22 million women and 5.5 million men aged between 50 and 84 years had osteoporosis in the European Union (EU) in 2010, whilst osteoporosis can be found in the list of 10 most important diseases named by the WHO. Due to changes in population demography, the number of men and women with osteoporosis might rise from 27.5 million in 2010 to 33.9 million in 2025, corresponding to an increase of 23%. The number of new fractures in the EU in 2010 was estimated at 3,5 million cases, in between these approximately 620.000 hip fractures, 520.000 vertebral fractures, 560.000 forearm fractures and 1.800.000 fractures of i.e. pelvis, rib, humerus, tibia, fibula, clavicle, scapula, sternum, and other femoral fractures. Two thirds of all fractures occurred in women. In 2010, the number of deaths causally related to fractures was estimated at 43.000. The corresponding cost of osteoporosis in the EU, also in 2010 figures, including pharmacological intervention, was estimated at €37 billion out of which costs of treating fractures represented 66%, pharmacological prevention 5% and long term fracture care 29%. The total health burden was estimated at 1 180 000 lost Quality Adjusted Life Years (QALY) for the EU. The total cost in the EU might rise from €98 billion in 2010 to €120 billion Euro in 2025. The use of osteoporosis drugs has increased considerably. Approved pharmacological interventions (bisphosphonates, strontium ranelate, raloxifene, denosumab and parathyroid hormone peptides) are widely available but their use is restricted by reimbursement policies. Alendronate (a bisphosphonate) is the most commonly prescribed agent, accounting for approximately a quarter of the total value of sales. The potential users/partners are pharmaceutical companies, excluding pure generic companies (lacking development resources, relevant lobbying and sales channel to the policy makers and practitioner) selling drugs in the indication osteoporosisUniversitat de València posted this:
New method for the production of metallic oxides with spinel structureThis procedure is faster, with lower energy consumption and generates purer spinels than known methods for spinel production. With this invention, it’s possible to provide new methods for obtaining spinels or other mixed oxides with a higher processability and versatility than those existing to date, allowing also for obtaining new spinels and removing the need for extremely costly phases in time or energy, including milling or heating at temperatures up to 1200ºC.Universitat de València posted this:
New method for the synthesis of inert metallic nanoparticlesThe most remarkable advantages provided by this technology are: • Rapidity of the metallic nanoparticle synthetic method, as it consists of only one step. • Efficiency, since size, shape and concentration of nanoparticles are controlled, as well as, their production in organic or inorganic soluble solution. • Reduced production costs, as high temperatures are required by other alternative laser ablation methods.
Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRIUniversidad de Alcalá-OTRI posted this:
New method of transmission and estimation of the arrival time of acoustic signals for localization systemsThe Research Group of Electronic Engineering Applied to Intelligent Spaces and Transportation (GEINTRA) of Alcalá University has developed a procedure to estimate the arrival instant of acoustic signals for localization systems based on a non-coherent and capable DFT-S-DMT * modulation to compensate the Doppler effect, for its application in acoustic localization systems. GEINTRA seeks companies from the Information and Communication Technologies (ICT) sector to sign technical cooperation agreements, commercial agreements with technical assistance and patent licensing agreements. * Discrete multi-tone modulation, widening by discrete Fourier transform
Universidad de AlicanteUniversidad de AlicanteUniversidad de Alicante posted this:
New method to detect spacer acquisition in CRISPR structuresInsertion of new CRISPR spacer units is very infrequent in most species. Detection of these events usually requires large screenings of CRISPR clusters of a high number of clones. In order to decrease the number of clones to be tested, it is possible to select adapted cells when such acquisition changes the immunity pattern (i.e. enables for the degradation of target molecules). This causes a bias against detection of insertions of other sequences and cannot be executed in cells with silenced CRISPR immunity. In this sense, the availability of a selectable tool for readily detecting spacer insertion independently of its consequences over the degradation of target genetic elements is highly advantageous compared to the methods currently in use.
CNIC (TTO)Spanish National Center for Cardiovascular Research (CNIC)CNIC (TTO)Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)
View ProfileCNIC (TTO) posted this:
New method to improve treatment of atrial fibrillationResearchers from the CNIC and HCSC have developed a system to guide ablation procedures in a patient-specific way in complex cases of persistent atrial fibrillation, identifying these key regions to be treated with great precision and specificity. Furthermore, it does not require additional equipment or consumables, but only software that could be implemented within any conventional electroanatomical browser, so it would not make current pulmonary vein isolation procedures more expensive, with the advantage of being able to perform patient-specific ablation in complex cases.
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)
Universitat de LleidaUniversitat de LleidaUniversitat de Lleida posted this:
New method to increase yolk color and egg nutritional qualityThe University of Lleida seeks industrial partners with expertise in the sector of crop production to adopt a new technology of optimized feed solution for egg producers (poultry market). The type of partner sought is for the regulatory codevelopment and commercialization of our solution under a technology license agreement.
- Universidad de AlicanteUniversidad de Alicante
Universidad de Alicante posted this:
New method to quantify the self-repair of polymeric materialsThe Adhesion and Adhesives Laboratory of the University of Alicante has developed a new method (equipment and process) to determine the degree of self-repair and to monitor the kinetics of self-repair of polymeric materials. The new method also makes it possible to follow the self-repair process of composites, ceramic materials, materials based on cement, mortar or concrete, and textile materials.
Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC posted this:
New method to test tuberculosis virulenceA new easy, fast and reliable method to determine the virulence of Mycobacterium tuberculosis (MTB) has been developed by a group of scientists from UPC and IGTP. Partners to further develop the technology and/or to establish comercial agreements along with technical cooperation are sought.
UNIVERSIDAD DE BURGOS posted this:
New methodology for the catalytic reduction of nitroaromatic compounds environmental friendlyThe invention relates to a new general method for the reduction of nitroarenes to anilines using a Mo(VI) catalyst and pinacol as reducing agent. The products obtained show excellent yields. It should be noted that this new method uses an easily available and non-toxic reducing agent that generates non-toxic byproducts which are easily separated from the amine synthesized.
UNIVERSIDAD DE BURGOSUNIVERSIDAD DE BURGOSUNIVERSIDAD DE BURGOS posted this:
New methods for the detection and discrimination of contaminants and organic metabolites of high environmental impact by means of fluorogenic probesThe research group develops new selective fluorogenic probes for organic molecules of low molecular weight and high social and environmental impact. The newly developed fluorogenic probes are able of show large differences of fluorescence in the presence of certain analytes and they are oriented to the resolution of detection problems for contaminants of high environmental impact for which a satisfactory solution does not exist, such as phosphorylating reagents from chemical weapons, methylmercury, cyanide ion, doping substances and recreational abuse drugs. By incorporation of the fluorogenic probes to silica nanomaterials, the research group generates new luminescent sensory materials of toxicological and environmental utility.
UNIVERSIDAD DE BURGOS posted this:
New methods for the detection and discrimination of contaminants and organic metabolites of high environmental impact by means of fluorogenic probesThe research group develops new selective fluorogenic probes for organic molecules of low molecular weight and high social and environmental impact. The newly developed fluorogenic probes are able of show large differences of fluorescence in the presence of certain analytes and they are oriented to the resolution of detection problems for contaminants of high environmental impact for which a satisfactory solution does not exist, such as phosphorylating reagents from chemical weapons, methylmercury, cyanide ion, doping substances and recreational abuse drugs. By incorporation of the fluorogenic probes to silica nanomaterials, the research group generates new luminescent sensory materials of toxicological and environmental utility.
- Universitat de LleidaUniversitat de Lleida
Universitat de Lleida posted this:
New microbial culture to control foodborne pathogens in fresh-cut fruitA new solution based on a microbial culture capable of inhibiting the growth of foodborne human pathogens such as Salmonella, Listeria monocytogenes and Escherichia coli in fresh-cut fruit. New microbial culture with demonstrated bio-preservative activity. The use of the proposed technology in the fresh-cut fruit industry prevents the development of food-borne pathogens, ensures food safety and maintains the product quality throughout the product shelf-life. This technology is complementary to existing preventive methods.
- CNIC (TTO)Spanish National Center for Cardiovascular Research (CNIC)CNIC (TTO)
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)
View ProfileCNIC (TTO) posted this:
New microRNAs for the diagnosis of cardiomyopathiesInflammation in the myocardium or myocarditis is a disease with heterogeneous aetiology, frequently caused by an infectious pathogen, toxins, drugs or by an autoimmune disorder. Its clinical variability and its nonspecific symptoms make the diagnosis of myocarditis a process that is not always easy. There is an urgent need for accurate, fast point-of-care tests that simultaneously provide diagnostic and prognostic information about a patient entering the hospital with symptoms of acute heart failure. CNIC researchers have identified the role of an specific miRNA in cardiomyopathies processes and have studied the differential expression in blood plasma of patients compared with healthy subjects. These miRNAs can be used as biomarker to improve the diagnosis of acute myocarditis.
Technology Transfer Office at Spanish National Center for Cardiovascular Research (CNIC)
Javier Montiel BonmatíUniversidad de AlicanteJavier Montiel Bonmatí posted this:
New multifunctional material for catalysis applicationsThe "Advanced Materials" research group at the University of Alicante has developed a foamed material comprising three phases: a structural matrix, at least one host phase, and a fluid. This material is characterized by the fact that the structural matrix comprises a plurality of interconnected porous cavities, the host phase(s) is/are housed within at least one porous cavity of the structural matrix and the fluid is housed within the porous cavities. The host phase(s) is/are housed within the porous cavities of the structural matrix without maintaining any bond with the latter. The structural matrix may consist of a material of a metallic, polymeric or ceramic nature or mixtures thereof. Meanwhile, the host phase(s) is/are a functional material, the fluid being a liquid or a gas. These materials have many potential uses, among which one is as a catalyst material or as a support for catalysts. Companies interested in the commercial exploitation of this material are sought through a patent license agreement.
Universidad de Alicante
- Javier Montiel BonmatíUniversidad de Alicante
Javier Montiel Bonmatí posted this:
New multifunctional material for controlled-drug-release implantsThe "Advanced Materials" research group at the University of Alicante has developed a foamed material comprising three phases: a structural matrix, at least one host phase, and a fluid. This material is characterized by the fact that the structural matrix comprises a plurality of interconnected porous cavities, the host phase(s) is/are housed within at least one porous cavity of the structural matrix and the fluid is housed within the porous cavities. The host phase(s) can be housed within the porous cavities of the structural matrix without maintaining any union or maintaining discrete unions with the latter. The structural matrix may consist of a material of a metallic, polymeric, ceramic nature or mixtures thereof. Meanwhile, the host phase(s) is/are a functional material, the fluid being a liquid or a gas. These materials have many potential uses, among which ones is as an implant material, with the additional possibility of exerting a controlled release of drugs. Companies interested in commercial exploitation of this material through a patent license agreement are sought.
Universidad de Alicante
Jordi ReverterInstitut Català de Nanociència i NanotecnologiaJordi Reverter posted this:
New Nanoporous Graphene materialA bottom up unique method build the holy graphene from molecular blocks. The molecular blocks used define the size and shape of the pores, which are identical with atomic precision. We can also control the chemical functionalization of the material. This material has semiconducting properties with a bandgap similar to Si, opening new applications for graphene-based materials. This new material can be used for sieving, sensing, (opto)electronics or its combinations.
Licensing Manager at Institut Català de Nanociència i Nanotecnologia
Universidad de Cádiz posted this:
New nanostructured catalyzers without noble metals and with low content in lanthanidesSince the 1990's, the mixed oxides of cerium and zirconium have replaced cerium oxide in the composition of the three-way catalyzers used in the automotive industry. The fundamental reason for this is the improved textural behaviour of the oxides of Ce/Zr, compared with the effectiveness of cerium oxide. These mixed oxides are also more effective in the exchange of oxygen with the medium. The Oxygen Storage Capacity (OSC) of the compound is therefore the key property for its application as a component in catalyzers. However, the rare earth metals which are the critical component of these catalyzers have currently increased considerably in price, due to greater demand and limited supply from the few exporting countries. The research group working in this field has been able to obtain nanostructured oxides of Ce/Zr and Ce/Zr/Y with low content in Ce that present very good oxygen storage properties. In addition, costly noble metals are not employed in their formulation, which represents an important economic advantage.- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
New nanostructured material for tissue regenerationA new ion release system for revascularization and tissue regeneration based of calcium phosphate glass nanoparticles has been patented and developed. Partners to further develop the technology and/or to establish commercial agreements along with technical cooperation are sought.
OTRI-Universidad de MálagaUniversidad de MálagaOTRI-Universidad de Málaga posted this:
New nanosystem to be applied over white adipose tissueThis invention is developed by the University of Málaga (UMA) in collaboration with Andalusian Public Health System and CIBER. They have developed a new nanosystem to be applied over white adipose tissue. This nanosystem changes white fat into brown fat.
Technology Transfer Office (TTO) at Universidad de Málaga- Javier Montiel BonmatíUniversidad de Alicante
Javier Montiel Bonmatí posted this:
New noble metal-free catalyst for the production of propylene oxideThe Institute of Materials of the University of Alicante has developed a new and cost-effective catalyst without noble metals to obtain propylene oxide from the selective oxidation of propylene. The catalytic system is characterized by not making use of dangerous or highly contaminating agents, and by not producing high quantities of reaction by-products. In addition, it shows a high selectivity towards propylene epoxide in the selective oxidation of propylene. Companies interested in acquiring this technology for commercial exploitation are sought.
Universidad de Alicante
University of Vigo posted this:
New non-destructive method for “in situ” monitoring of anticorrosive protection of organic coatingsPaint coating is one of the most used methods to delay corrosion process in metallic structures. Metal corrosion is the main reason of metallic infrastructure deterioration (bridges, boats, planes…) causing failures in numerous industrial areas. The economic loss due to corrosion is estimated at about 4% of the Gross Domestic Product (GDP) in industrialized countries. Due to the serious consequences of this phenomenon, it is essential to develop effective methods for early detection of coatings failures and establishment of deterioration mechanisms. However nowadays, most of the inspection methods are indirect, destructive and based on deterministic or probabilistic models, which limits the coatings performance assessment on the in real operating conditions. The Corrosion Engineering and Materials Research Group (ENCOMAT) proposes a solution to this problem with a new device and a direct and non-destructive test based on electrochemical impedance spectroscopy (EIS). The main novelty of the device and procedure is the new portable sensor adaptable to any surface. The device, fixable by vacuum to the surface under study, makes possible the measurement of the electrochemical interfacial impedance. That is the main parameter of interest for adherence quality and anti-corrosion performance. The procedure reduces testing time and allows in situ assays to be performed. Innovative aspects and advantages
University of Vigo posted this:
New non-destructive method for “in situ” monitoring of anticorrosive protection of organic coatingsPaint coating is one of the most used methods to delay corrosion process in metallic structures. Metal corrosion is the main reason of metallic infrastructure deterioration (bridges, boats, planes…) causing failures in numerous industrial areas. The economic loss due to corrosion is estimated at about 4% of the Gross Domestic Product (GDP) in industrialized countries. Due to the serious consequences of this phenomenon, it is essential to develop effective methods for early detection of coatings failures and establishment of deterioration mechanisms. However nowadays, most of the inspection methods are indirect, destructive and based on deterministic or probabilistic models, which limits the coatings performance assessment on the in real operating conditions. The Corrosion Engineering and Materials Research Group (ENCOMAT) proposes a solution to this problem with a new device and a direct and non-destructive test based on electrochemical impedance spectroscopy (EIS). The main novelty of the device and procedure is the new portable sensor adaptable to any surface. The device, fixable by vacuum to the surface under study, makes possible the measurement of the electrochemical interfacial impedance. That is the main parameter of interest for adherence quality and anti-corrosion performance. The procedure reduces testing time and allows in situ assays to be performed.
University of Vigo posted this:
New non-destructive method for “in situ” monitoring of anticorrosive protection of organic coatingsThe main novelty of the device and procedure is the new portable sensor adaptable to virtually any surface. The device, fixable by vacuum to the surface under study, makes possible the measurement of the electrochemical interfacial impedance, that is the main parameter of interest for adherence quality and anti-corrosion performance.University of Vigo posted this:
New non-destructive method for “in situ” monitoring of anticorrosive protection of organic coatings Authors: Xosé Ramón Nóvoa and Carmen Pérez.Paint coating is one of the most used methods to delay corrosion process in metallic structures. Metal corrosion is the main reason of metallic infrastructure deterioration (bridges, boats, planes…) causing failures in numerous industrial areas. The economic loss due to corrosion is estimated at about 4% of the Gross Domestic Product (GDP) in industrialized countries. Due to the serious consequences of this phenomenon, it is essential to develop effective methods for early detection of coatings failures and establishment of deterioration mechanisms. However nowadays, most of the inspection methods are indirect, destructive and based on deterministic or probabilistic models, which limits the coatings performance assessment on the in real operating conditions. The Corrosion Engineering and Materials Research Group (ENCOMAT) proposes a solution to this problem with a new device and a direct and non-destructive test based on electrochemical impedance spectroscopy (EIS). The main novelty of the device and procedure is the new portable sensor adaptable to any surface. The device, fixable by vacuum to the surface under study, makes possible the measurement of the electrochemical interfacial impedance. That is the main parameter of interest for adherence quality and anti-corrosion performance. The procedure reduces testing time and allows in situ assays to be performed. Innovative aspects and advantages
- Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRI
Universidad de Alcalá-OTRI posted this:
New organo-metallic catalysts for the manufacture of polymersA research group from the Inorganic Chemistry Department of Alcalá University has developed a technology that presents a range of catalysts based on coordination complexes and organometallic, active in functionalization processes (expoditation, hydrosilylation) and polymerization of different organic substrates (olefins and cyclic esters). They are metal complexes belonging to the first transition groups (groups 4-6) and elements from the main groups (groups 1,2 and 13). Its application is aimed at the synthesis of materials with new properties (silicon polymers, biodegradable plastics, polyesters) and the production of small molecules with high added value, used as starting products in many industrial processes (epoxides, silanes). The group is looking for manufacturing agreements and joint venture agreements with companies from the agrofood industry, construction and petrochemicals. 
Otava Research InstituteOtava Research InstituteOtava Research Institute posted this:
New Original Squaraine Dye for protein detectionUkrainian Laboratories represents the original new squaraine dye for the protein detection. The dye is already synthesized and ready to use for biomedical application. The dye has a significant increase in the fluorescence intensity in the presence of protein (123 times) and does not change its intensity in the presence of nucleic acids.
- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
New orthotic gloveNew orthotic glove designed to amplify hand strength . An actuated hand exoskeleton useful for old or disabled people who have not enough strength in their hands has been patented and developed.
- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
New orthotic glove designed to amplify hand strengthAn actuated hand exoskeleton useful for old or disabled people who have not enough strength in their hands has been patented and developed. This new technology allows amplification of hand-grasping force. Partners to further develop the device and/or to establish commercial agreements along with technical cooperation are sought.
- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
New orthotic glove designed to amplify hand strength An actuated hand exoskeleton useful for old or disabled people who have not enough strength in their hands has been patented and developed. This new technology allows amplification of hand-grasping forcThe Challenge Partial hand disability represents a serious problem for many people, who although they have mobility and sensitivity in their hands, are not strong enough to hold a simple mug. For example, people with diseases, elderly or people who have suffered a traffic accident. In order to improve their quality of life, the design of devices such as the exoskeleton presented is so important. Currently, there are some similar devices nevertheless most of them need external energy and sophisticated drive mechanisms, complicating their use and maintenance.
