Universidad de Alcalá-OTRI posted this:Carbosilane dendrimers and their use as antiviralsThe research group in "Dendrimers for Biomedical Applications" of the University of Alcalá presents these highly branched macromolecules synthesized from a polyfunctional nucleus, of carbosilane structure and functionalized in its periphery with anionic groups that give the macromolecule a negative net charge. In addition, the invention relates to the use of the dendrimers as an antimicrobial and the process for obtaining them. The group seeks to reach collaboration agreements, licensing or commercial agreements with technical assistance, with companies in the biotechnology, pharmaceutical and biomedicine sectors in general.
Fundació URV posted this:Predictive pharmacokinetics/ pharmacodynamic (system biology) evaluation of drug and other compound’s efficacy and safetyPharmacokinetics/ pharmacodynamic (system biology) PBPK/PD model is a powerful mechanistic tool used for designing of trials in different phases, prospective and retrospective analysis for bridging gaps in an experiment, target validation, safety and efficacy analysis and early identification of risk associated with specific group of population.
Universidad de Alcalá-OTRI posted this:Carbosilane dendrimers with polyphenolic groups. Uses as antioxidants and anticancer.The "Dendrimer for biomedical applications Research Group" at Alcalá University presents dendritic macromolecules with skeleton of carbosilane nature that contain in their structure polyphenolic groups (GPF). These compounds are powerful antioxidants and free radical scavengers, as well as anticancer agents, with application in sectors such as food, cosmetics and pharmaceutical industry. The invention provides a process for its procurance and uses.
Universidad de Alcalá-OTRI posted this:Carbosilane dendritic compounds homo and heterofunctionalizedA Spanish research group from the Department of Organic and Inorganic Chemistry of Alcala University has developed a highly branched macromolecules called dendrimers or dendrons, with carbosilane structure and functionalized on its periphery with anionic or cationic groups, providing the macromolecule a net negative or positive charge respectively. The invention also concerns the dendrimers’ procurement process and their biomedical applications, particularly as carriers of drugs or nucleic acids (such ODN, siRNA, dsRNA or DNA), or as therapeutic agents with antiviral or antibacterial activity. The group is looking for companies in the biomedical sector to reach licensing agreements, collaboration and commercial agreements with technical assistance.
Centre Technology Transfer CITTRU posted this:Chitinase A – potential applications in various fields.Methods of chitinase purification, used so far, consisted of multi-stage and expensive procedures. Affinity chromatography was also used with so-called affinity tags. These tags could interfere with the functions of chitinase, and their cut-off was associated with the next step of digestion and purification. The proposed method of Jagiellonian University’s chitinase A purification using affinity chromatography with the involvement of G proteins is fast and efficient single-step. In addition, use of direct conjuction of chitinase and protein G eliminates the need of chitinase tagging, which may disturb protein functions, whereas their cutting requires additional digesting and purifying stage.
Centre Technology Transfer CITTRU posted this:Anti-histidine and Anti-arginine Tag DNA aptamers for biotechnological applicationsThe subject of the offer are unique sequences of single-stranded DNA aptamers with high affinity to any molecule (peptide, protein or DNA derivative) containing His-Tag and Arg-Tag and their application in biotechnology in analysis of His-Tagged and Arg-Tagged molecules.
Yissum - Research Development Company of the Hebrew University posted this:Research & Services | Modern cell and molecular biology research of diabetesResearch & Services | Modern cell and molecular biology research of diabetes Project ID : 34-2010-2440
Yissum - Research Development Company of the Hebrew University posted this:Oxidized Cellulose Used to Bind and Prevent Allergic Reaction in Asthma, Seasonal Allergies and Atopic DermatitisA new composition of matter comprising microparticles with both oxidized cellulose and glucans. The composition includes pharmaceutically acceptable carrier and as an active ingredient oxidized cellulose. Preferable the oxidized cellulose should be formed as microparticles and the combimation can be used for the treatment of asthma and allergy. keywords: formulation, allergy Project ID : 7-2006-398
Yissum - Research Development Company of the Hebrew University posted this:Improving Liver Regeneration in Older Patients(YZ1May13- Courrently, use of Leptin/ Akt inhibitors such as bpV(phen) / mTor inhibitors)Project ID : 6-2008-2177
Yissum - Research Development Company of the Hebrew University posted this:Medical Imaging Method and Systemmethod and system for analysis of color change in images in the human body. The method is used for diagnosis of such disorders that changes in color of tissues occeurs. Keywords: image processing, algorithm, dental care With Hadasit Project ID : 7-2006-854
Yissum - Research Development Company of the Hebrew University posted this:Non-Viral Delivery Method for Gene TherapyA novel technology of non-viral delivery of genetic material (genes, pDNA, antisense, oligonucleotides etc., termed: gene) has been developed. The gene is encapsulated in biocompatible and biodegradable polymeric nanoparticles that provide efficient transfection, controlled-release and gene therapy. Keywords: Oligonucleotides, gene therapy Project ID : 12-2006-172
xrqtc posted this:Modeling of silica supported catalyst as an additional tool for catalyst characterization and optimizationThe technology is able to perform enough accurate solid state IR and NMR modelling resulting in more reliable structures than M-L distances obtained by Extended X-ray absorption fine structure. the group has developed small scaled but still reliable models suitable for the exploration of the full reaction mechanism including, if necessary, the most relevant deactivation pathways.
Technology Transfer Office
Ventura Medical Technologies posted this:A new surgery kit for Pectus ExcavatumFrom the cooperation between Ventura Medical Technologies and Hospital Parc TaulÃ, a new method, Taulinoplastia, and a new surgery kit, Pectus Up, are born to correct the Pectus Excavatum. This new technique presents suitable advantages over current used methods. Pectus Up is a set of tools and implants manufactured with the aim of treating Pectus Excavatum with the Taulinoplastia, being less painful and with a reduced post-operative time than other methods.
Yissum - Research Development Company of the Hebrew University posted this:Use of Derivatives of Valproic Acid and 2-Valproenic Acid Amides for the Treatment of Mania Bipolar DisorderUse of Derivatives of Valproic Acid and 2-Valproenic Acid Amides for the Treatment of Mania Bipolar Disorder Project ID : 12-2006-1208