Research & Technology Organization
Universidad de Alcalá-OTRI posted this:Carbosilane dendrimers and their use as antiviralsThe research group in "Dendrimers for Biomedical Applications" of the University of Alcalá presents these highly branched macromolecules synthesized from a polyfunctional nucleus, of carbosilane structure and functionalized in its periphery with anionic groups that give the macromolecule a negative net charge. In addition, the invention relates to the use of the dendrimers as an antimicrobial and the process for obtaining them. The group seeks to reach collaboration agreements, licensing or commercial agreements with technical assistance, with companies in the biotechnology, pharmaceutical and biomedicine sectors in general.
UNIVERSIDAD DE BURGOS posted this:Direct “in situ” determination of ascorbic acid (Vitamin C) using a device formed by three disposable screen-printed electrodesNew device for direct “in situ” detection of ascorbic acid in different types of liquid samples, for example biological samples or food products. The equipment consists of an electrode system formed by three disposable electrodes, obtained by silkscreen printing.
UNIVERSIDAD DE BURGOS posted this:Manufacturing process optimization method for metallic components in the industry.The vast majority of metal products in the industrial level are obtained from sheet metal forming, which are used in a diversity of applications, from car bodies, appliances and planes, together with beverage packaging. In order to define the final design and structure of a stamped component there are two fundamental steps: the manufacturing process to perform the part and the structural simulation to overcome the requirements for performance specifications. The University of Burgos has patented procedure for the design and manufacturing of cold stamped metal part components that establishes an interconnection between the process simulation and the structural simulation during the development of the stamped components, so the mechanical properties of the material are modified in function of the predefined level got in each zone of the component.
Cracow University of Technology posted this:Method of preparation of oxide catalystThe invention relates to an innovative method of obtaining a chromium/ZrO2 catalyst using an ultrasonic field in its synthesis. The catalyst is designed to VOC combustion (especially methane, contained in waste gases). The main advantages of the chrome-containing catalyst obtained by sonication method are its high thermal stability, lower diffusion limits and lower costs compared to palladium catalyst.
Small and Medium Enterprise
Sandra Moczulska posted this:
Technology Broker at Technology Transfer Office (University of Warsaw)
Merck KGaA posted this:Technology for Lysophosphatidic Acid (LPA) Receptor antagonistsMerck has developed and patented the results of its intense R&D activities for the identification of small organic molecules as antagonists to certain LPA receptors (LPAR1, -R2, -R3). Herein described are LPA-R2 receptor selective inhibitors. Based upon a rational screening cascade established, compounds have been identified and characterized with regard to their specific in vitro and cellular activities. The package includes access to the IP, experimental results, and materials. Merck offers the unique chance to acquire this promising program.
Merck KGaA posted this:Novel Pharmaceutical Salt Forming Counterions with Increased Dissolution Rates and SupersaturationOne of the major obstacles in developing promising New Chemical Entities (NCEs) as Active Pharmaceutical Ingredients (APIs) is their low solubility and therefore poor bioavailability. Merck has developed a novel class of salt forming anions as counter-ions for protonated free base APIs which result in an accelerated dissolution rate and increased solubility by supersaturation of the NCE. The invention is based on a systematic thermodynamic and molecular engineering approach to design the above mentioned anions resulting in crystal lattices of API salts with weak Coulomb interactions.
Merck KGaA posted this:Technology for Serum and Glucocorticoid regulated kinase (SGK) inhibitorsMerck KGaA, Darmstadt, Germany, has developed and patented the results of its intense R&D activities for the identification of small organic molecules as SGK1 inhibitors. Based upon a rational screening cascade established, compounds have been identified and characterized with regard to their specific in vitro, cellular and in vivo activities. The package includes access to the IP, experimental results, and materials. Merck KGaA, Darmstadt, Germany, offers the unique chance to acquire this promising program.
Small and Medium Enterprise
Creative Biogene posted this:Human HTR2B-FLAG Stable Cell Line-CHO5-HT2B (5-hydroxytryptamine receptor 2B) is a receptor for serotonin. It is expressed in many peripheral and central nervous system tissues, including stomach fundus, liver kidney, muscle, intestine and brain. 5-HT2B receptors are responsible for many cardiovascular and central nervous system functions, such as blood vessel contraction, platelet shape changes, neuronal sensitization to tactile stimuli, and mediation of the hallucinogenic effects of phenylisopropylamin hallucinogens.
UNIVERSIDAD DE BURGOS posted this:Polymer Conductor with properties according to your needsThe University of Burgos has developed a new solid electrical conductive polymer material, preferably as film or coating, using non-conductive polymers. This material can be used in the production of resistive or conductive sensors for substances of interest, both in gas phase and in solution, or for use in electrical and electronic systems.
UNIVERSIDAD DE BURGOS posted this:Detection and quantification “in situ” of mercury, copper and nitrites in water and food products using a polymeric detectorThe method developed in this patent is based on the use of cross-linked copolymers, which act as colorimetric sensors, for the detection and / or quantification of divalent metals: mercury [Hg (II)] and copper [Cu (II)]; and anions: nitrite (NO2-). It is applicable in different matrices, both aqueous mediums and food products.
Fundació URV posted this:Breath test for dengue disease diagnosisElectronic nose device capable of detecting volatile organic compounds (VOCs) present in the breath of peopel suffering from Dengue. Dengue is a mosquito-borne viral infection causing a severe flu-like illness and, sometimes, it causes a potentially lethal complication called severe (haemorrhagic) dengue. In up to 80% of the cases, the disease is asymptomatic or mild, and can even pass unobserved. There is no specific treatment for Dengue or for Haemorrhagic Dengue, but its diagnosis at an early stage reduces the mortality rate below 1%. The current diagnosis of dengue is carried out in epidemiology laboratories by blood tests, which may be negative in the early stages of the disease. In this invention, a new system for non-invasive, early, fast and easy to use diagnosis test for Dengue disease from exhaled breath analysis has been developed.
Alphanosos posted this:Anti pyoderma solution in spray (veterinary)We are licensing our anti-staphylococci herbal mix extract (patent pending) with a great safety profile for veterinary use as anti-pyoderma spray (or other formulation). Successful animal model results are available. Available as API or finished product ( in preparation, Q2/2018 ).