SARS-CoV-2 Papain-like Protease Targeted Library

Summary of the technology

We offer SARS-CoV-2 Papain-like Protease (PLpro) Targeted Library, which contains 1051 compounds with predicted activity against this protease.

Otava Research Institute
Otava Research Institute

Details of the Technology Offer

Lpro is an attractive target being a crucial role in cleavage and maturation of viral polyproteins, assembly of the replicase-transcriptase complex, and disruption of host responses. Otava offers the SARS-CoV-2 Papain-like Protease (#PLpro) Targeted Library contains 1051 compounds with predicted activity against this enzyme.
The library has been designed with receptor-based virtual screening (flexible docking of Drug-like Collection into protease cleavage site) using the crystal structure of SARS-CoV-2 PLpro.
The library comprises in stock drug-like compounds only, cherry-picking is possible.

Related Keywords

  • Biological Sciences
  • Medicine, Human Health
  • Biostatistics, Epidemiology
  • Biology / Biotechnology
  • Molecular design Technology
  • Infectious Diseases
  • Pharmaceutical Products / Drugs
  • Covid-19

About Otava Research Institute

Otava Institute is a global provider of one-stop integrated research solutions for business and life science. Our team includes chemists, biologists, physicists whose combined efforts contribute to the complex contract research projects for pharmaceutical, agro, cosmetic and material science industries.We are dedicated to providing clients with outstanding service in these key areas and will continue to push boundaries to remain an industry front-runner. Each day we expand our core competencies delivering of new technologies to meet all the customer’s needs.

Our location in Toronto Ontario, Canada provides our clients with the added advantage of North American IP rules and regulations and secure communication and logistics. Our Ukraine – based R&D facilities represented with the Ukrainian Laboratories, that is cooperating with leading Ukrainian research institutions and carries out research work in the format of outsourcing.

We work as a preferred partner to many of the world’s top 10 pharma firms, and hundreds of other companies, providing support with creative solutions for complex technical compound issues. Our scientific knowledge, combined with our research and manufacturing capability, enables us to support chemical processing and production without ever compromising on quality.

Our experience, dedication, and commitment to quality make us an ideal partner for discovery stage research.

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