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Yeda posted this:
One Step Synthesis of L-DOPACurrent synthetic pathways of the standard Parkinson’s disease treatment, L-DOPA (levodopa), are complicated, requiring multiple steps, and depend upon the use of either hazardous starting compounds or producing toxic side products. The present technology offers an alternative synthetic method that is greatly simplified for the production of LDOPA. Using only Tyrosine as a feedstock, the production of L-DOPA is efficient without the generation of side products, and ecologically friendly as no toxic starting materials or side products are used or produced.
Jordi ReverterInstitut Català de Nanociència i NanotecnologiaJordi Reverter posted this:
one-step method for the postsynthetic modification of metal-organicframeworksMetal-organic frameworks (MOFs) are among the most attractive porous materials known today. Their high surface-to-mass ratio makes them extremely useful in many processes, from gas sorption, storage and separation, to catalysis, drug delivery and heat exchange. Typically they are modified post-synthesis (PSM) to optimise their chemical functionality and/or pore surface to a specific application. We propose a new approach to PSM.
Licensing Manager at Institut Català de Nanociència i Nanotecnologia
Sección de Innovación:Valorización y EmprendimientoUniversitat de ValènciaSección de Innovación:Valorización y EmprendimientoInnovation Consultant at Universitat de València
View ProfileSección de Innovación:Valorización y Emprendimiento posted this:
One-step water recycling for inorganic and organic pollutantsResearchers from Universitat de València in collaboration with Università della Calabria have developed a new patented technology related to water recycling and Metal-Organic Frameworks. The patent application consists of new materials that eliminate inorganic and organic pollutants in a single step. In this way, these materials avoid the multi-step sequential protocols that are currently applied in water recycling plants. The materials of this invention are based on Multivariate Metal-Organic Frameworks (MTV-MOFs). They have a wide range of applications in water recycling plants such as pharmaceutical, textile, food, plastic, mining... etc, as well as for agricultural and domestic use.
Innovation Consultant at Universitat de València
Vigilantes do Sono posted this:
Online therapy for curing insomnia and improving sleepWe are, Vigilantes do Sono. We provide a drug-free self-treatment therapy that helps people improve their sleep by changing behaviours and adjusting bed-sleep environment connection. It is based on a scientific method known as "Cognitive Behaviour Therapy for Insomnia" (CBTi). During 2 months, the patient is guided by a chatbot called "Sonia". Daily, Sonia teaches sleep techniques and monitors the patient's sleep and habits. During the treatment users have a community to connect to peers to share experiences and help each other on this sleep improvement journey and can be accompanied by their health care professional via technical reports. What differentiate us from other alternatives is that we are cheaper than alternatives (10x-100x less expensive) and we maintain frequent interactions with user, optimizing people behaviour change. It is also healthier and more sustainable then using medicines. Our preliminary results (soon to be published in a scientific paper) show that people that follows our therapy increases total sleep time by 79 minutes and reduce time to fall asleep in 30 minutes. Those results are better than most medicines and in-person therapy. Other studies suggests that improving sleep via CBTi also improves depression, anxiety, menopause, cognitive performance, and overall well-being.
Boris Zubry posted this:
Open Reduction Internal Bone FixationAvicenna Therapeutic Technologies, LLC is an early stage start-up developing new types of fasteners (patents pending) to replace screws in the internal bone fixation. Those fasteners will allow usage of biodegradable materials exclusively thus, eliminating the need for removal of the metal hardware or any adjustments. This method and device would reduce the healing process dramatically and cut the cost of this treatment by almost a half.
Scientist
Jorian Bos posted this:
OPEN TELEHEALTH - Remote COVID19 patient monitoringAre you struggling with an expensive and a too disease-specific Mobile Health solution? Introducing OpenTeleHealth - a powerful turnkey solution that will grow your business and optimize your workflow today.
Other at EIT Digital
Vilnius UniversityVilnius UniversityVilnius University posted this:
Optical 3D Micro- and Nano-formation of BioplasticsThe present technology allows printing complex 3D micro- and nano-structures from environmentally friendly plant-derived material – acrylated epoxidized soybean oil (AESO). Non-toxicity and high biodegradability enable application in biomedicine, micro-optics and nanophotonics.
Yeda posted this:
Optical Bus for a Multi-Core ProcessorThe exponential increase in computational power over the last decades is running into a bottle-neck – the only way of getting more computing power per chip is to integrate multiple-cores, but the problem with multiple-cores is the complex wiring system, used for inter-core communication. This technology, developed at the Weizmann Institute of Science propose a radically new idea that replaces wires and fibers altogether, by an appropriately designed integrated optical chip layer that serves the same purpose with less complexity. It eliminates the use of wires thus saving valuable space, reducing power consumption and subsequently internal heat production. It further allows for high number of interconnected processors on the same chip and improves inter-core connectivity by 100-1000-fold, ultimately increasing computational power.
CSIR posted this:
Optical Coherence Tomography (OCT) Fingerprint Sensor: Laser Identity VerificationWhat would happen if you don’t have fingerprints? Burns, ageing, solvents and a number of other conditions could remove your obvious external fingerprint. Our technology allows a sub-dermal scan of the finger using a laser to obtain a print even if there is superficial damage to the finger pad (we call this an internal finger print). This innovation will be particularly useful for crime scenes, as the laser scan can be carried out without disturbing the crime scene. Additionally, the laser is capable of identifying faked fingerprints.
Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC posted this:
Optical communication receiver with an SQRT nonlinear equalizerIn a high bit rate optical transmission, the inclusion of a simple non-linear equalizer implementing the square-root mathematical function, just after the photo-detector and before the conventional electronic equalizer (FIR, MLSE, analog,..), linearizes the overall systems and highly improves the transmission performances.Yeda posted this:
Optical Conversion of Ultra-Fast Laser PulsesUltra-fast lasers are highly used in both academia (to monitor chemical & biological reactions) and industry (for submicron resolution products). Mainly, the emission source of these lasers is Ti-Sapphire, which produces very short pulses (about ten femtoseconds – 10-14sec) but only in the Near Infrared (NIR) region (700nm-1000nm). Producing ultra-fast pulses in the visual range is very limited. Prof. Yaron Silberberg and his coworkers developed a technique for converting these ultra-fast pulses in the NIR to the visible spectrum while keeping the pulse duration in a wide range of wavelengths and maintaining high conversion efficiency.
uacoopera posted this:
Optical pressure sensor based on zirconia nanostructuresA group of researchers from a Portuguese university has developed the concept of a gas pressure gauge based on the control of the luminescence from zirconia nanostructures. The invention aims to measure the gas pressure based on the nanoparticles emission that is different depending on the amount of gas molecules surrounding the nanoparticles. Comparing with existing solutions, the advantage of this process, which operate in a pressure range of interest for various market sectors (ex. Food industry), is the absence of electrical contacts. The university is looking for companies that develop this type of solution on an industrial scale for the further joint development of specific applications or technology licensing.- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
OPTICAL REMOTE NODE DEVICE AND SUPPORT EQUIPMENT FOR CONSTRUCTING AND EXTENDING FIBRE-OPTIC ACCESS NETWORKSThe Remote Node performs all-optical interfacing between a metropolitan ring and the access trees to the homes, thus enabling a transparent metro-access converged optical network. The device performs the functions of wavelength add&drop, ring protection and optical amplification with remote pumping. It is composed by a number of optical elements not requiring electrical power supply. 
OTRI-Universidad de MálagaUniversidad de MálagaOTRI-Universidad de Málaga posted this:
Optical stabilization system for signal enhancement in spectrometric measurements with mechanical fluctuationsInstrumentation for analytical spectrometry has evolved dramatically in terms of sensitivity and miniaturization in recent years, making the instrumentation more compact and versatile for both desktop and field applications. However, signal quality worsens under mechanical fluctuations or energetic movements of the instrument, which yields inaccurate measurements. This invention tries to solve this problem of signal and can be applied to all kind of stand-off analytical instrumentation with an open optical path.
Technology Transfer Office (TTO) at Universidad de Málaga
Larisa SheloukhovaKyoto UniversityLarisa Sheloukhova posted this:
Optimization of precise gene editing in human iPS cellsThe discovery of CRISPR-Cas system for genome editing has revolutionized experimental biology. Research labs all over the world are using multiple variations of the system to answer fundamental questions in genetics, model diseases, and develop therapies. However, precise gene editing to generate single-nucleotide modifications needed for accurate disease modeling and therapeutic development has seen limited success. The Woltjen Lab has developed methods to optimize precise gene editing in iPS cells by combining a series of techniques using CRISPR-Cas9.
Global Tech Commercialization at Kyoto University
Unismart - University of Padua FoundationUnismart - University of Padua FoundationUnismart - University of Padua Foundation posted this:
Optimized analysis of slurry in agricultureThis patented system uses data fusion techniques in order to obtain accurate data of the chemical composition of these byproducts, which are potentially pollutant. The use of slurry from animal farming or anaerobic digestion for fertilization is beneficial for the economy of animal or biogas farms but may cause the pollution of ground or surface water if distribution is done incorrectly.
CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas posted this:
OPTOBIOTICS: Novel antibacterial proteins activated by blue lightCSIC has developed a chimeric protein that, when expressed in bacteria, changes its structure upon absorption of blue light, thus generating protein aggregates (amyloids) that inhibit bacterial growth Industrial partners from the pharmaceutical industry are being sought to collaborate through a patent licence agreement An offer for Patent Licensing
RAMOT at Tel Aviv University Ltd.RAMOT at Tel Aviv University Ltd.RAMOT at Tel Aviv University Ltd. posted this:
Oral Mucosa-derived Stem Cells: A Unique Population for the Prevention and Treatment of Ischemic Heart FailureStem cells (SC) are considered crucial building blocks for any regenerative strategy. Adult oral mucosa (OM) is a unique source for generating adult pluripotent stem cell (OPSC) populations. This uniqueness consists in the fact that 95% of the OM whole populations in culture (1st – 8th passages) express markers of embryonic and mesenchymal SC. Thus, in contradistinction to known sources which comprise very low numbers of SC, OPSC generation for clinical use is simple and cost effective and does not require cumbersome cost-consuming purification steps. The general objective is to lay the foundation for the development of a variety of products based on the pluripotency and simple and cost effective generation of billions of OPSC. The major aim of the proposed project is to develop a product for the treatment of ischemic heart failure (IHF). This product which will serve as a proof of concept was selected based on medicals needs, market cap and time to market. The specific aims of the proposal are: 1. To develop a cardiac product aimed at treating ischemic heart failure (IHF). The aim is to test the safety and therapeutic effect of OPSC on experimental IHF in a minipig model. 2. To strengthen the intellectual property by fully characterizing the profile of OPSC. The prevalence of IHF continuously increases (1 million new cases every year in the western world) and currently the market cap is estimated in the range of billions. Project ID : 10-2011-260
Nerea AlonsoFundación Biomedica Galicia SurNerea Alonso posted this:
ORAL STREPTOCOCCI WITH BACTERICIDAL ACTIVITYUse of a new species of streptococcus, Streptococcus downii, and/or bioactive compounds derived from it for the treatment of infections of the oral cavity, such as caries and periodontitis. S. downii belongs to the group of healthy commensal oral streptococci.
Innovation Manager at Fundación Biomedica Galicia Sur- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Organic derivatives for the manufacture of electronic devicesCSIC have developed organic derivatives, low cost, with possibility of modifying its molecular structure, including different substitutions, improving the properties of electronic semiconductor. These molecules present not only interesting electronic properties which make them active for the manufacture of solar cells, specifically organic photovoltaic cells, but also an intense blue color which allows it so be used as a dye in the textile industry. Industrial partners from the energy, electronic and textile are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing UNIVERSIDAD DE BURGOS posted this:
Organic molecule capable of detecting explosivesResearchers from the University of Burgos have designed a method to synthesize a compound that is extremely useful in the detection of explosives, such as triacetone triperoxide. This explosive is very simple to prepare and extremely difficult to detect. The project has been subsidized by NATO and, given the potential of the molecule, a patent has been applied for to protect and commercialize it.
UNIVERSIDAD DE BURGOS posted this:
Orientation of fibers within composites: improvement of material properties and manufacturing processIt is well known that there are correlations between fiber orientation and mechanical and/or physical properties of the composite. Knowing the real orientation of the fibers within a composite material can help to optimize the design and manufacturing process. A composite material contains materials of different densities (fibrous material and matrix), and these have different X-rays absorption capacity, generating different grey levels in scanned images. This allows later identification and separation by the computed tomography scan (CT-scan), a non-destructive technique that provides scanned images with the orientations of fibrous or filamentary components contained inside a composite material, and therefore its mechanical and/or physical properties. However the interpretation of these images depends on the criterium of the technicians, being a subjective opinion. This subjective interpretation can be solved by our computer implemented method that allows a numeric objective valoration of the orientations of fibres or filaments inside the composite. The final result is a more efficient use of the fiber, and therefore an optimal design, from both structural and economical points of views.
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Overcoming resistance to Beta-lactam antibiotics in Bacterial speciesCSIC and the University of Würzburg have developed a new method to eliminate antibiotic-resistant bacterial infections using classical antibiotics previously discarded due the occurrence of antibiotic resistance. Industrial partners from the pharmaceutical industry are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing
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- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Paper-based temperature sensor with high sensitivityThe CSIC has developed a thermo-resistive sensor comprising a semiconductor material onto a paper substrate. The use of this type of materials together with deposition technique of semiconductor element allow to design a thermo-resistive sensor with high sensitivity to abrupt temperature changes being up to an order of magnitude more sensitive than analogous sensors based on graphite. The use of paper as substrate makes this sensor cheap, easy to produce and biodegradable. The incorporation of this device in fabrics allows to monitor body temperature. Likewise, when integrated in packaging, it allows to record thermal history of goods. Industrial partners from the electronic components and sensors sectors or companies from textile and paper industry are being sought to collaborate through a patent license agreement.
- CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas
CSIC - Consejo Superior de Investigaciones Científicas posted this:
Particle identification using a high precision system based on multi-frequency measurements of resonant platesCSIC has developed a new system that allows to identify and classify nanometric and micrometric particles. This system is based on the changes produced at different resonance frequencies of thin plate type structures when these particles are adsorbed onto their surface. This technology represents an important achievement in the field of nanomechanical spectrometry and is suitable for the identification and classification of viruses, bacteria or proteins. Industrial partners manufacturers of lab equipment are being sought to collaborate through a patent license agreement. An offer for Patent Licensing
University of Alberta, Technology Transfer ServicesUniversity of Alberta, Technology Transfer ServicesUniversity of Alberta, Technology Transfer Services posted this:
Partnering Opportunity: Effervescent Powders for InhalationUniversity of Alberta and Alberta Health Services researchers have jointly developed a new type of dry-powder inhalable carrier particle with an active release mechanism to disperse therapeutics more effectively. Most advanced product candidate based on this delivery system is an inhalable effervescent doxorubicin nanoparticle formulation; it demonstrated significantly improved survival time in a small cell lung cancer mouse model.
Universitat de València posted this:
Passive sampler for monitoring atmospheric pollutants (VERAM)The most remarkable advantages provided by this technology are: o Versatility, it is possible to sample a big number of pollutants using a single device containing a combination of solid phases. o Greater adsorption capacity and high analytic sensitivity with smaller sampling time than market available devices. o Rapidity and low cost of pollutant analysis. Thermal desorption and head space injection minimize sample handling, do not require the use of solvents and reduce the time of analysis. o Cheap passive samplers with a fast and simple fabrication procedure. o VERAM permits a multidirectional sampling differing from radial or one-way sampling devices with encapsulated solid phases.
