Pharmaceutics Technology Offers

Consejo Superior de Investigaciones Científicas posted this:

Overcoming resistance to Beta-lactam antibiotics in Bacterial species CSIC and the University of Würzburg have developed a new method to eliminate antibiotic-resistant bacterial infections using classical antibiotics previously discarded due the occurrence of antibiotic resistance. Industrial partners from the pharmaceutical industry are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing

Overcoming resistance to Beta-lactam antibiotics in Bacterial species

Consejo Superior de Investigaciones Científicas posted this:

Purine derivatives for the treatment of neurodegenerative diseases CSIC has synthesized several substituted purine derivatives that are capable of inhibiting the activity of the CDC7 kinase. This inhibitory activity makes them useful for the treatment of neurological diseases. The compounds developed are, therefore, a new therapeutic alternative for Alzheimer's disease, amyotrophic lateral sclerosis or frontotemporal dementia. Industrial partners from pharmaceutical industry are being sought to develop and commercialized the compounds through a patent licence agreement. An offer for Patent Licensing

Purine derivatives for the treatment of neurodegenerative diseases

Consejo Superior de Investigaciones Científicas posted this:

New treatment for epidermolysis bullosa and fibrosis CSIC, Carlos III University of Madrid and CIEMAT have repositioned drugs that stimulate endogline expression and modulate the TGF-β route for a new clinical use in the treatment of fibrosis, such as epidermolysis bullosa (EB). EB includes a heterogeneous group of rare hereditary diseases of the skin in which in its infantile incidence the patients are known as "butterfly children". It is a new therapy for a rare pathology, with potential in a wide spectrum of fibrosis, which would improve the possibilities of treatment of patients, improving their quality of life. Industrial partners from the pharmaceutical industry are being sought for its development in a wide variety of fibrotic pathologies through a patent licence agreement. An offer for Patent Licensing

New treatment for epidermolysis bullosa and fibrosis

Consejo Superior de Investigaciones Científicas posted this:

Control of neurodegenerative diseases with benzothiazole-benzamide derivatives CSIC has developed a group of heterocyclic compounds derived from a privileged structural nucleus with the capacity to inhibit the LRRK2 enzyme. This inhibitory activity makes them useful in the treatment of neurodegenerative diseases affected by this enzyme, among which Parkinson's disease and Alzheimer's disease stand out. Pharmaceutical companies interested in the development and commercialization of these compounds under a patent license are sought. An offer for Patent Licensing

Control of neurodegenerative diseases with benzothiazole-benzamide derivatives

Consejo Superior de Investigaciones Científicas posted this:

Compounds for the treatment and prevention of immune-mediated inflammatory diseases CSIC and the University of Athens have found that secoiridoids, such as oleacein and oleocanthal, are useful to prevent or treat illnesses that results in immune-mediated gastrointestinal alterations. A company dealing with pharmaceutical or nutraceutical compositions is sought for licensing agreement. An offer for Patent Licensing

Compounds for the treatment and prevention of immune-mediated inflammatory diseases

Consejo Superior de Investigaciones Científicas posted this:

Biotechnological production of 11α hydroxylated steroids using recombinant bacteria.CSIC has developed a procedure for the biotechnological production of 11α hydroxylated steroids by generating and subsequent use of recombinant bacteria. These recombinant bacteria allow to perform microbial biotransformation processes that result in 11αhydroxylated steroid compounds from raw materials such as phytosterols and intermediate products efficiently and economically. These compounds have numerous applications in pharmacology. Companies are sought for implementing and commercializing the new technology under patent license agreement. An offer for Patent Licensing

Biotechnological production of 11α hydroxylated steroids using recombinant bacteria.

Consejo Superior de Investigaciones Científicas posted this:

Peptide for cancer control linked to IL13R CSIC has developed a peptide capable of inhibiting the signaling of IL-13 mediated by IL13Rα2. This peptide alone or within a nanoparticle or virus-like particles can be used in a pharmaceutical composition for the treatment of pathologies in which IL13Rα2 is overexpressed. This composition would be useful in the treatment and control of metastasis of colon cancer and other tumors (i.e glioblastoma), as well as in other pathologies such as asthma, atopic dermatitis or fibrosis. Industrial partners are being sought to develop and commercialized the products through a patent licence agreement. An offer for Patent Licensing

Peptide for cancer control linked to IL13R

Consejo Superior de Investigaciones Científicas posted this:

Piperidine derivatives for the control of Parkinson's and Alzheimer's CSIC has synthesized a series of piperidine derivatives that are capable of inhibiting the activity of the enzyme phosphodiesterase-8 (PDE8). This inhibitory activity makes them useful for the treatment of neurodegenerative diseases in which this enzyme is overexpressed. The compounds developed are, therefore, a new therapeutic alternative for Alzheimer's disease, and Parkinson, among others. Industrial partners from pharmaceutical industry are being sought to develop and commercialized the compounds through a patent licence agreement. An offer for Patent Licensing

Piperidine derivatives for the control of Parkinson's and Alzheimer's

Ivan Rodriguez Rosello posted this:
Licensing Manager at Universidad de Alicante

New compound to successfully treat degenerative diseases of the retina The research group "Neurobiología del sistema visual y terapia de enfermedades neurodegenerativas" of the University of Alicante has discovered the use of the compound 3-(2-isothiocyanatethyl)-5-methoxy-1H-indol, and its pharmaceutically acceptable salts, for the preventive or therapeutic treatment of degenerative diseases of the retina, such as: pigmentary retinosis, diabetic retinopathy, glaucoma or age-related macular degeneration. This compound has demonstrated, in vitro and in vivo, its neuroprotective capacity in various models under laboratory conditions. This compound is characterized by a 20% increase in neuronal survival, a 35% increase in visual acuity, and a 15% increase in contrast sensitivity. Therefore, it has very promising properties that could position it as the first effective treatment against degenerative diseases of the retina. We are looking for companies interested in acquiring this patent for commercial exploitation.

New compound to successfully treat degenerative diseases of the retina

Centre Technology Transfer CITTRU posted this:

A new method of the stereoselective synthesis of chosen medicines The subject of the offer is a new method of an asymmetric reduction of prochiral ketones and imines used in the synthesis of commonly used medicines, e.g. hormonal (eg. Cincalcet), pulmonary (eg. Salbutamol) and neurological ones (eg. Rasagiline).

A new method of the stereoselective synthesis of chosen medicines

uacoopera posted this:
Licensing Manager at uacoopera

Magnetic nanoparticles for selective enrichment of proteins in complex mixtures New method for preparing ion chelating magnetic nanoparticles, which allow selective protein enrichment, namely metalloproteases (MMPs) and His-tagged proteins, from complex mixtures.

Magnetic nanoparticles for selective enrichment of proteins in complex mixtures

Mahesh Kulkarni posted this:
Assistant Vice President-Business Development at Praj Industries Limited

Sodium Pyruvate an platform chemical for energy booster Sodium Pyruvate is biochemical used in nutrition and Healthcare industry. It is important intermediate for production of Perindopril and Levodopa. Novel Biotransformation process developed using yeast as biocatalyst. Fermentation and Downstream has been optimized from bench scale bioreactors upto10 liter pilot scale.

uacoopera posted this:
Licensing Manager at uacoopera

Innovative methodology for nanoencapsulation of montelukast in cyclodextrin Cyclodextrin is a nano-sized capsule that allows increasing the stability and aqueous solubility of active pharmaceutical ingredients such as montelukast. This technology comprehends an alternative method to obtain an amorphous solid composed by montelukast and cyclodextrin. In alternative to conventional methodologies, this method allows the encapsulation to occur without requiring the use of solvents and the formation of degradation products.

Innovative methodology for nanoencapsulation of montelukast in cyclodextrin

Universidad de Alcalá-OTRI posted this:

Carbosilane dendrimers with terminal thiol groups on their surface. Their preparation and their uses.The research group in «Dendrimers for biomedical applications» of the University of Alcalá presents the procedure for obtaining and using carbosilane dendrimers with terminal thiol groups on their surface, as antioxidants and radical scavengers for their application in the food industry, cosmetic and pharmaceutical. The group seeks to reach licensing agreements, collaboration agreements or commercial agreements with technical assistance, with enterprises from the food industry, cosmetic, biotechnology, Biomedicine or pharmaceutical sector.

Carbosilane dendrimers with terminal thiol groups on their surface. Their preparation and their uses.

Universidad de Alicante posted this:

Holographic sensor for detection of adulterants in essential oils The research group of Holography and Optical Processing of the University of Alicante has developed a holographic technique for the detection of adulterants in essential oils. This technique is able to detect different types of adulterants qualitatively. In addition, a quantitative measurement of the degree of adulteration of an essential oil can also be performed by means of pre-calibration of the sensor for a particular adulterant. The sensor could be miniaturized and manufactured at a low cost compared to traditional methods of analysis such as gas chromatography and high performance liquid chromatography. The sensor can be used by unqualified personnel.

Holographic sensor for detection of adulterants in essential oils

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