Universidad de Alcalá-OTRI posted this:Carbosilane dendrimers with terminal thiol groups on their surface. Their preparation and their uses.The research group in «Dendrimers for biomedical applications» of the University of Alcalá presents the procedure for obtaining and using carbosilane dendrimers with terminal thiol groups on their surface, as antioxidants and radical scavengers for their application in the food industry, cosmetic and pharmaceutical. The group seeks to reach licensing agreements, collaboration agreements or commercial agreements with technical assistance, with enterprises from the food industry, cosmetic, biotechnology, Biomedicine or pharmaceutical sector.
Research & Technology Organization
UNIVERSIDAD DE ALICANTE posted this:Holographic sensor for detection of adulterants in essential oilsThe research group of Holography and Optical Processing of the University of Alicante has developed a holographic technique for the detection of adulterants in essential oils. This technique is able to detect different types of adulterants qualitatively. In addition, a quantitative measurement of the degree of adulteration of an essential oil can also be performed by means of pre-calibration of the sensor for a particular adulterant. The sensor could be miniaturized and manufactured at a low cost compared to traditional methods of analysis such as gas chromatography and high performance liquid chromatography. The sensor can be used by unqualified personnel.
UATEC - Unidade de Transferência de Tecnologia posted this:Ohmic heating reactor for chemical synthesis, the method and its applicationsIn ohmic heating electrical energy is dissipated in heat with a very high efficiency (electrodes in contact with the reaction medium), resulting in fast and uniform heating and in the increase of charged species movement. As in the case of the heating with microwave radiation, electrical energy is transformed into thermal energy. However, on contrary of heating with microwave radiation (penetration depth of microwave radiation in absorbing media is limited) the penetration depth is virtually unlimited and the extent of heating is regulated only by the spatial uniformity of electrical conductivity throughout the reaction medium and the time spent in the ohmic reactor. Thus, the direct scaling of the ohmic heating for the pilot or industrial scale shouldn’t have the limitations presented by microwave radiation heating. It is also possible to reduce reaction times and increase the energy efficiency of chemical reactions
Cracow University of Technology posted this:New preparation method of silver nanoparticles suspension and silver nanoparticles suspension for medical, cosmetic and pharmaceutical application.Subject of this offer is the preparation method of silver nanoparticles suspension by reduction of silver salt by using reducing agent of natural origin and in the presence of a stabilizer. In this method, the following reducing agents are used apiproduct or extract of amber. The obtained nanoparticles can be applied in various industries, but the largest future is in the medical area, and as ingredient in cosmetic compositions due to the presence of non-toxic ingredients.
Cracow University of Technology posted this:Suspension containing gold or silver nanoparticles or a mixture thereof and a production method thereofThe present invention relates to a process for the preparation of nanosilver and nanogold using an aqueous extract of dog rose, white grape and knotweed. Substances which were extracted from these plants act both as reducer of silver and gold ions and stabilizing agent of forming silver and gold nanodispersion, preventing them from agglomeration and inhibiting their growth, so that the resulting particle size does not exceed 100 nm.
University of Vigo posted this:Pyridazin-3(2H)-one Derivatives as Selective Inhibitors of Monoamine Oxidase-B Isoform (MAO-B)The pyridazine ring is a privileged fragment found in compounds with very different pharmacological properties, such as antihypertensive, antiplatelet, anti-inflammatory, antinociceptive, antidepressant, hypoglycemic, antiinfective or anticancer agents, many of them being pyridazin-3(2H)-one derivatives. The pyridazine ring is also included in polycyclic compounds acting as MAO-B inhibitors. However, simple pyridazin-3(2H)-one derivatives have not been described so far as selective MAO-B inhibitors. The present invention provides novel pyridazin-3(2H)-one derivatives substituted at C4, C5 or C6 with several dithiocarbamate moieties that selectively inhibit the MAO-B activity and whose structure is unrelated to those currently available.
University of Vigo posted this:Procedure for the extraction of biosurfactants contained in corn steep liquorsNowadays, most of the pharmaceutical and cosmetic products in the market contain chemically synthesized surfactants in its composition. In many cases, these surfactants are the same as those used in regular cleanup activities. In order to get more natural and biocompatible products, it would be interesting to include natural surfactants instead of chemical surfactants in the preparation of these pharmaceutical and cosmetic products. These biosurfactants are also present in the formulation of greener nanoparticles, replacing the chemical surfactants currently used in the preparation thereof. Most biosurfactants have antimicrobial activity, which would improve the properties of certain nanoparticles, as well as many pharmaceutical and cosmetic products. The main disadvantage of biosurfactants industrial production is related to the high cost compared to chemically synthesized surfactant production. The solution proposed by the Chemical Engineering research group at the University of Vigo, is the development of eco-friendly simple extraction of biosurfactant from a corn wet-milling industry byproduct, such as corn wash liquors, better known as "corn steep liquor (CSL)", which could compete in terms of cost production with its chemical counterparts.
Institute of Chemical Research of Catalonia posted this:Valorization of HFC-23: trifluoromethylation reactions- clean production of trifluromethylcopper reagent - process works at room temperature and atmospheric pressure - inexpensive and abundant trifluoromethyl source - environmentally friendly process - low-cost reagents - valorization of fluoroform: a by-product of PTFE production - Versatile reagent allowing for a broad scope of reactivity
Institute of Chemical Research of Catalonia posted this:Crysforma: services in pharmaceutical solid state developmentCrysforma provides complete scientific support for the discovery, analysis and scale-up of polymorphs, hydrates, amorphous phases, salts and co-crystals of active pharmaceutical ingredients or intermediates. Crysforma has developed its own crystallization screening methodology based on the combination of several crystallization procedures. We use high-throughput crystallization systems controlled by highly skilled scientists to maximize the information drawn from each experiment. Our projects are always carried out in close collaboration with the client, adapted to the customer's needs and under strict confidentiality conditions.
UATEC - Unidade de Transferência de Tecnologia posted this:System for the collection , storage and exhaled alveolar air conditioning for clinical analysisA group of researchers from Portuguese university developed a device that allows the collection and storage of the exhaled alveolar air by humans. The invention aims simultaneously to overcome some of the technical difficulties in the current state of the art, such as i) little or no response in the selective collection of alveolar air fraction ii) the inability to couple systems that allow concentration/extraction of analytes of interest iii) the inexistence of systems to the storage of the collected biofluid under controlled conditions and iv) the inability to collect exhaled air in liquid or vapor state. The university is looking for companies interested in the industrial production of the equipment and its commercialization.
Universidad de Alcalá-OTRI posted this:Carbosilane dendritic compounds homo and heterofunctionalizedA Spanish research group from the Department of Organic and Inorganic Chemistry of Alcala University has developed a highly branched macromolecules called dendrimers or dendrons, with carbosilane structure and functionalized on its periphery with anionic or cationic groups, providing the macromolecule a net negative or positive charge respectively. The invention also concerns the dendrimers’ procurement process and their biomedical applications, particularly as carriers of drugs or nucleic acids (such ODN, siRNA, dsRNA or DNA), or as therapeutic agents with antiviral or antibacterial activity. The group is looking for companies in the biomedical sector to reach licensing agreements, collaboration and commercial agreements with technical assistance.
Institute of Chemical Research of Catalonia posted this:ERTFlow: flow reaction technologies and process intensificationERTFLOW is a technology development unit from the Institute of Chemical Research of Catalonia (ICIQ), generated by the know-how produced by the research group of Prof. Miquel Pericàs, to develop and implement technical solutions in process intensification. Our goal is to develop propietary technologies related to catalysis and flow chemistry and offering products and services to the fine chemical, pharmaceutical and biotechnological industries for the production of new products with high added value and guide them in the paradigm change from batch to flow.
Centre Technology Transfer CITTRU posted this:Nanocapsules for delivery of lipophilic compounds and method of their preparationThe present invention provides novel biocompatible “core-shell” systems and the surfactant-free method of their preparation using macromolecular compounds. Biocompatible nanocapsules with liquid cores which enable effective encapsulation of hydrophobic compounds are stabilized without low molecular weight surfactants. These beneficial features significantly increase the range of possible applications.
Universidad de Alcalá-OTRI posted this:Disposable electrodes based on filtered nanomaterials.A Spanish research Group from Analytical Chemistry, Physical Chemistry and Chemical Departments at University of Alcalá (Spain) has designed and developed different disposable electrodes constituted exclusively by conducted nanomaterials for analytical measurement of electroactive molecules for (bio-) sensoric in relevant areas such as health, agri-food and environmental. The group is looking for companies in the chemistry, clinical, agri-food and environmental sectors to reach licensing agreements or collaboration and commercial agreements for technical assistance.