University of Vigo posted this:Procedure for the extraction of biosurfactants contained in corn steep liquorsNowadays, most of the pharmaceutical and cosmetic products in the market contain chemically synthesized surfactants in its composition. In many cases, these surfactants are the same as those used in regular cleanup activities. In order to get more natural and biocompatible products, it would be interesting to include natural surfactants instead of chemical surfactants in the preparation of these pharmaceutical and cosmetic products. These biosurfactants are also present in the formulation of greener nanoparticles, replacing the chemical surfactants currently used in the preparation thereof. Most biosurfactants have antimicrobial activity, which would improve the properties of certain nanoparticles, as well as many pharmaceutical and cosmetic products. The main disadvantage of biosurfactants industrial production is related to the high cost compared to chemically synthesized surfactant production. The solution proposed by the Chemical Engineering research group at the University of Vigo, is the development of eco-friendly simple extraction of biosurfactant from a corn wet-milling industry byproduct, such as corn wash liquors, better known as "corn steep liquor (CSL)", which could compete in terms of cost production with its chemical counterparts.
Consejo Superior de Investigaciones Científicas posted this:Purine derivatives for the treatment of neurodegenerative diseasesCSIC has synthesized several substituted purine derivatives that are capable of inhibiting the activity of the CDC7 kinase. This inhibitory activity makes them useful for the treatment of neurological diseases. The compounds developed are, therefore, a new therapeutic alternative for Alzheimer's disease, amyotrophic lateral sclerosis or frontotemporal dementia. Industrial partners from pharmaceutical industry are being sought to develop and commercialized the compounds through a patent licence agreement. An offer for Patent Licensing
Consejo Superior de Investigaciones Científicas posted this:Compounds for the treatment and prevention of immune-mediated inflammatory diseasesCSIC and the University of Athens have found that secoiridoids, such as oleacein and oleocanthal, are useful to prevent or treat illnesses that results in immune-mediated gastrointestinal alterations. A company dealing with pharmaceutical or nutraceutical compositions is sought for licensing agreement. An offer for Patent Licensing
Consejo Superior de Investigaciones Científicas posted this:Enzymatic production of 2,5-furandicarboxylic acid from 5-methoxymethylfurfuraa a l l CSIC, University of Zaragoza and Technische Universität Dresden have developed an enzymatic composition and its use as an enzymatic cascade for the production of 2,5-furandicarboxylic acid (FDCA) from 5-methoxymethylfurfural (MMF). This cascade is self-sustained with the only consumption of atmospheric oxygen and the MMF itself. The method can be applied to the conversion of MMF into FDCA step in the bioplastic producing industry, switching from the current inorganic catalysts employed to the use of enzymes for the FDCA production. Industrial partners are being sought to develop and commercialize the enzymatic composition through a patent licence agreement. An offer for Patent Licensing
Research & Technology Organization
Radoslaw Rudz posted this:
Licensing Manager at Centre Technology Transfer CITTRU
Technology Transfer Office
Institut Català d'Investigació Química (ICIQ) posted this:Photochemical metal-free method of amination of C-H bondsA new method for the metal-free amination of C-H bonds has been developed. The method uses readily available reagents (iodine, trilfuoromethylsuylfonamide, diacetoxyiodobenzene) and light to insert a sulfonamide moiety into a C-H bond. the method has been successfully used in the preparation of various APIs (memantine, rasagiline, sertraline). The method takes place in mild conditions and allows avoiding the use of transition metal catalysis and multiple-steps procedures. Partners are sought for the joint development of commercial applications of the method.
Yury Savinykh posted this:
Professor / PhD.
uacoopera posted this:Ohmic heating reactor for chemical synthesis, the method and its applicationsIn ohmic heating electrical energy is dissipated in heat with a very high efficiency (electrodes in contact with the reaction medium), resulting in fast and uniform heating and in the increase of charged species movement. As in the case of the heating with microwave radiation, electrical energy is transformed into thermal energy. However, on contrary of heating with microwave radiation (penetration depth of microwave radiation in absorbing media is limited) the penetration depth is virtually unlimited and the extent of heating is regulated only by the spatial uniformity of electrical conductivity throughout the reaction medium and the time spent in the ohmic reactor. Thus, the direct scaling of the ohmic heating for the pilot or industrial scale shouldn’t have the limitations presented by microwave radiation heating. It is also possible to reduce reaction times and increase the energy efficiency of chemical reactions
Institute of Chemical Research of Catalonia posted this:Method for the preparation of linear polyacenes and building blocks of organic electronic components.A new synthetic method to access precursors of linear polyacenes has been developed. The method allows for the preparation of hydrogenated polyacenes which are readily converted into the corresponding polyacene. Prepared materials are useful starting materials in the preparation of organic field effect transistors (OFETs), used in organic electronics. The method paves the way to the preparation of more efficient OFET components.
Fundació URV posted this:Environmentally friendly processing of thermosets by two-stage sequential aza-Michael addition and free-radical polymerization of amine-acrylate mixturesEnvironmentally friendly preparation of thermosets for applications on thermosensitive substrates. A two-step curing process, which consists in an Aza-Michael addition at room temperature, followed by UV radical polymerization of acrylates or methacrylates amine formulations without the need of adding solvents. The presence of amines in the structure suppress the radical inhibition by oxygen, which is a typical drawback in radical polymerizations. The invention allows leading the curing in two separate stages with a stable intermediate material, being the process controlled by the amount of amine in the formulation.
Fundació URV posted this:Catalytic wastewater treatment for organic matter removalThe catalytic technology allows you to remove high concentrations of COD (40.000-200.000ppm) at atmospheric pressure. All kind of organic compunds are removed (biodegradable and non biodegradable ones). The catalyst life is around 2-3 years. It is an exothermic process, so the energy needed for the process is just for the start up. The process works at 250-350ºC.
Universidad de Alcalá-OTRI posted this:Heterogeneous NCH complex of palladium and their uses as recoverable catalysts.AA research Group from the Department of Organic Chemistry and Inorganic Chemistry at University of Alcalá (Spain) has designed catalysts suitable for organic synthesis processes based on supported N-heterocyclic carbene (NHC) complexes of palladium, which are magnetically separable after their use, reusable and resistant to metal leaching, and useful in carbon-carbon coupling reactions. The group is looking for companies in the chemical and pharmaceutical sectors to reach licensing agreements or collaboration and commercial agreements for technical assistance.
Fundació URV posted this:Acrylic thermosets prepared by dual curing at room temperature fit for coatings and adhesivesFormulations for the preparation of thermosets by dual curing, at room temperature in two stages, stable over time, from the reaction of amine compounds with 2 or more N-H bonds with a vinyl compounds with a minimum of 2 double α, β- conjugated bonds to carbonyl ester groups and further polymerization of vinyl groups in excess, with completely controlled characteristics of the material at the intermediate stage.
Universidad de Alicante posted this:New family of dyesThe main innovative aspects of this technology regarding current methods of synthesis are: • The indolizine dyes are obtained in one step from commercially available materials, unlike current procedures, which involve multiple steps. This is an advantage in the production process, as it reduces costs, increases the final yield and less waste is generated. • The procedure is based on a very simple treatment which produces indolizine dyes in yields higher than 70%. • The present invention does not require the use of inert atmosphere, dry solvents or physical activation (heat or radiation) to obtain the final product. • Unlike other methodologies for preparing indolizine dyes (requiring temperatures around 100°C), this process is carried out at room temperature and atmospheric pressure, which simplifies the method and decreases production costs. • This is an environmentally friendly technology because it does not use solvents such as dioxane, pyridine, chloroform or benzene, which are used in other methods and are characterized by their high toxicity and demonstrated carcinogenicity. • The selectivity of the reaction is very high. The indolizine dye is obtained with absolute control, obtaining a single isomer of the ten possible.