Organic Substances Technology Offers

Consejo Superior de Investigaciones Científicas posted this:

Purine derivatives for the treatment of neurodegenerative diseases CSIC has synthesized several substituted purine derivatives that are capable of inhibiting the activity of the CDC7 kinase. This inhibitory activity makes them useful for the treatment of neurological diseases. The compounds developed are, therefore, a new therapeutic alternative for Alzheimer's disease, amyotrophic lateral sclerosis or frontotemporal dementia. Industrial partners from pharmaceutical industry are being sought to develop and commercialized the compounds through a patent licence agreement. An offer for Patent Licensing

Purine derivatives for the treatment of neurodegenerative diseases

Consejo Superior de Investigaciones Científicas posted this:

Compounds for the treatment and prevention of immune-mediated inflammatory diseases CSIC and the University of Athens have found that secoiridoids, such as oleacein and oleocanthal, are useful to prevent or treat illnesses that results in immune-mediated gastrointestinal alterations. A company dealing with pharmaceutical or nutraceutical compositions is sought for licensing agreement. An offer for Patent Licensing

Compounds for the treatment and prevention of immune-mediated inflammatory diseases

Consejo Superior de Investigaciones Científicas posted this:

Enzymatic production of 2,5-furandicarboxylic acid from 5-methoxymethylfurfura CSIC, University of Zaragoza and Technische Universität Dresden have developed an enzymatic composition and its use as an enzymatic cascade for the production of 2,5-furandicarboxylic acid (FDCA) from 5-methoxymethylfurfural (MMF). This cascade is self-sustained with the only consumption of atmospheric oxygen and the MMF itself. The method can be applied to the conversion of MMF into FDCA step in the bioplastic producing industry, switching from the current inorganic catalysts employed to the use of enzymes for the FDCA production. Industrial partners are being sought to develop and commercialize the enzymatic composition through a patent licence agreement. An offer for Patent Licensing

Enzymatic production of 2,5-furandicarboxylic acid from 5-methoxymethylfurfura

FUNDITEC posted this:

Development of technology in Surface Functional Coatings Functional coatings based on biopolymers obtained from renewable sources. Edible coatings for enhancing of shelf-life and quality in food. Functional coatings for glass and metal based on sol-gel chemistry.

Radoslaw Rudz posted this:
Licensing Manager at Centre Technology Transfer CITTRU

Hydrogel hybrid material for the reconstruction of bone defects The subject of the offer is an injectable, hydrogel hybrid material that can be used to construct a bioactive cell scaffold of a minimal invasivity. This scaffold may be located in place of a bone defect thus enabling reconstruction of bone tissue. Application: in tissue engineering for the reconstruction of orthopedic and dental bone defects.

Hydrogel hybrid material for the reconstruction of bone defects

Institut Català d'Investigació Química (ICIQ) posted this:

Photochemical metal-free method of amination of C-H bonds A new method for the metal-free amination of C-H bonds has been developed. The method uses readily available reagents (iodine, trilfuoromethylsuylfonamide, diacetoxyiodobenzene) and light to insert a sulfonamide moiety into a C-H bond. the method has been successfully used in the preparation of various APIs (memantine, rasagiline, sertraline). The method takes place in mild conditions and allows avoiding the use of transition metal catalysis and multiple-steps procedures. Partners are sought for the joint development of commercial applications of the method.

Yury Savinykh posted this:
Professor / PhD.

Effective natural stimulants for plants The product is made of environmentally friendly raw materials – peat or fir foot without the addition of synthetic chemicals. Stimulants are non-toxic, do not have mutagenic properties, show immunostimulatory and adaptogenic properties. The use of stimulants can increase the yield of grain and vegetables by 20 - 60 %, accelerates the maturation, the onset of biological and technological maturity by 3-6 days, reduces fungal and bacterial morbidity of plants by 2-4 times, helps to reduce storage losses, accelerates seed germination and increases their germination and activity of the initial growth, accelerates the growth of the root system and increases its mass by 1.2-1.8 times.

Effective natural stimulants for plants

uacoopera posted this:

Ohmic heating reactor for chemical synthesis, the method and its applications In ohmic heating electrical energy is dissipated in heat with a very high efficiency (electrodes in contact with the reaction medium), resulting in fast and uniform heating and in the increase of charged species movement. As in the case of the heating with microwave radiation, electrical energy is transformed into thermal energy. However, on contrary of heating with microwave radiation (penetration depth of microwave radiation in absorbing media is limited) the penetration depth is virtually unlimited and the extent of heating is regulated only by the spatial uniformity of electrical conductivity throughout the reaction medium and the time spent in the ohmic reactor. Thus, the direct scaling of the ohmic heating for the pilot or industrial scale shouldn’t have the limitations presented by microwave radiation heating. It is also possible to reduce reaction times and increase the energy efficiency of chemical reactions

University of Vigo posted this:

Procedure for the extraction of biosurfactants contained in corn steep liquors Nowadays, most of the pharmaceutical and cosmetic products in the market contain chemically synthesized surfactants in its composition. In many cases, these surfactants are the same as those used in regular cleanup activities. In order to get more natural and biocompatible products, it would be interesting to include natural surfactants instead of chemical surfactants in the preparation of these pharmaceutical and cosmetic products. These biosurfactants are also present in the formulation of greener nanoparticles, replacing the chemical surfactants currently used in the preparation thereof. Most biosurfactants have antimicrobial activity, which would improve the properties of certain nanoparticles, as well as many pharmaceutical and cosmetic products. The main disadvantage of biosurfactants industrial production is related to the high cost compared to chemically synthesized surfactant production. The solution proposed by the Chemical Engineering research group at the University of Vigo, is the development of eco-friendly simple extraction of biosurfactant from a corn wet-milling industry byproduct, such as corn wash liquors, better known as "corn steep liquor (CSL)", which could compete in terms of cost production with its chemical counterparts.

Institute of Chemical Research of Catalonia posted this:

Valorization of HFC-23: trifluoromethylation reactions - clean production of trifluromethylcopper reagent - process works at room temperature and atmospheric pressure - inexpensive and abundant trifluoromethyl source - environmentally friendly process - low-cost reagents - valorization of fluoroform: a by-product of PTFE production - Versatile reagent allowing for a broad scope of reactivity

Valorization of HFC-23: trifluoromethylation reactions

Institute of Chemical Research of Catalonia posted this:

Method for the preparation of linear polyacenes and building blocks of organic electronic components.A new synthetic method to access precursors of linear polyacenes has been developed. The method allows for the preparation of hydrogenated polyacenes which are readily converted into the corresponding polyacene. Prepared materials are useful starting materials in the preparation of organic field effect transistors (OFETs), used in organic electronics. The method paves the way to the preparation of more efficient OFET components.

Method for the preparation of linear polyacenes and building blocks of organic electronic components.

Frederic Ratel posted this:
Licensing Manager at Institute of Chemical Research of Catalonia

Catalytic process for the preparation of carboxylic acids from haloalkanes or alkenes.A convergent process for the preparation of terminal carboxylic acids by carboxylation of mixtures of bromoalkenes or mixtures of olefins has been developed. The process is catalytic in nickel and allows preparing a unique product from a mixture of starting materials (regioconvergent process), which allows saving several synthetic and separation steps in processing and renders possible the use of the process with exhaust streams from crackers. The process is useful for the production of fatty acids.

Fundació URV posted this:

Environmentally friendly processing of thermosets by two-stage sequential aza-Michael addition and free-radical polymerization of amine-acrylate mixtures Environmentally friendly preparation of thermosets for applications on thermosensitive substrates. A two-step curing process, which consists in an Aza-Michael addition at room temperature, followed by UV radical polymerization of acrylates or methacrylates amine formulations without the need of adding solvents. The presence of amines in the structure suppress the radical inhibition by oxygen, which is a typical drawback in radical polymerizations. The invention allows leading the curing in two separate stages with a stable intermediate material, being the process controlled by the amount of amine in the formulation.

Environmentally friendly processing of thermosets by two-stage sequential aza-Michael addition and free-radical polymerization of amine-acrylate mixtures

Fundació URV posted this:

Catalytic wastewater treatment for organic matter removal The catalytic technology allows you to remove high concentrations of COD (40.000-200.000ppm) at atmospheric pressure. All kind of organic compunds are removed (biodegradable and non biodegradable ones). The catalyst life is around 2-3 years. It is an exothermic process, so the energy needed for the process is just for the start up. The process works at 250-350ºC.

Universidad de Alcalá-OTRI posted this:

Heterogeneous NCH complex of palladium and their uses as recoverable catalysts.AA research Group from the Department of Organic Chemistry and Inorganic Chemistry at University of Alcalá (Spain) has designed catalysts suitable for organic synthesis processes based on supported N-heterocyclic carbene (NHC) complexes of palladium, which are magnetically separable after their use, reusable and resistant to metal leaching, and useful in carbon-carbon coupling reactions. The group is looking for companies in the chemical and pharmaceutical sectors to reach licensing agreements or collaboration and commercial agreements for technical assistance.

Heterogeneous NCH complex of palladium and their uses as recoverable catalysts.

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