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University of WaterlooUniversity of WaterlooUniversity of Waterloo posted this:
Restoring GLP-1 incretin to treat Type 2 Diabetes mellitus and obesityBackground Glucagon-like peptide 1 (GLP-1) is a hormone secreted by L-cells of the gastrointestinal tract in response to incoming glucose. GLP-1 is referred to as an incretin, which serves to potentiate insulin secretion by beta-cells of the pancreas, ensuring that adequate amounts of insulin are released to allow for proper disposal of glucose after consuming a meal. Healthy beta-cells fail to secrete enough insulin when incretin levels do not rise. It is known that GLP-1 levels and action are reduced/impaired in obesity and in Type 2 Diabetes Mellitus (T2DM). People with obesity and T2DM often exist in a state of elevated chronic subacute inflammation.
UNIVERSIDAD DE BURGOS posted this:
Reusable device that allows the circulation of a constant volume of electrolyte in tests on rotating bending fatigue test machines.Rotating bending fatigue machine are essential for testing material properties. It is usual to face samples of the different materials to conditions that differ from the usual ones, such as corrosive environments, to evaluate their behavior. Researchers from the University of Burgos have developed a device that allows this type of analysis to be carried out, allowing, unlike many of the current methods, that the material to be analyzed is in direct contact with the electrolyte responsible for generating conditions other than the usual ones. Additionally, thank to the design of the device, it can be used in more than one experiment.
Yeda posted this:
Reusable Gold Nanostars Substrates for Signal Amplification for DiagnosticsNumerous spectroscopic techniques utilize signal enhancement from surfaces of nanoparticles linked to analyte molecules. However, existing surface-enhanced spectroscopies (SES) are based on solution-based nanoparticles dispersion and are unsuitable for solid substrates. Dr. Shimanovich and her team (led by Dr. Solomonov) have developed a set of spiked gold nanostructures (also called “nanostars”, “nanoflowers”, “nanourchins”) embedded directly on solid-state substrates. These functionalized nanostar-substrates enable signal amplification in solid substrates and serve as highly sensitive transducers in various spectroscopies, including surface-enhanced Raman (SERS), surface-enhanced circular dichroism (SECD), localized surface plasmon resonance (LSPR), and surfaceenhanced fluorescence spectroscopy (SEFS) of molecules of biological, organic or inorganic origin.
Ron Jimdar posted this:
Reusable Rigid Container to Dispenses Content within a Flexible Pouch Formed to FitA packaging lift innovation that dispenses content within a pouch designed to drop in a reusable vessel. The reusable vessel (rigid tube, Jar or container) lifts,scrapes and suspends viscous and non viscous content from the bottom and sides of a flexible pouch eliminating any waste left behind while keeping fresh content at the top.
Jordi ReverterInstitut Català de Nanociència i NanotecnologiaJordi Reverter posted this:
Reversible colour-change polymer filmA polymer film coating for glass and plastic surfaces that allows reversible colour changes in response to variations in temperature, exposure to light or both
Licensing Manager at Institut Català de Nanociència i Nanotecnologia
Yeda posted this:
Reversible Operation of Molecular Switches on Solid SurfacesMolecular photoswitches are light-responsive molecules with potential applications in a broad range of systems with on-demand functionalities. While molecular photoswitches have been extensively studied in solution, their immobilization to dry, planar surfaces generally renders them photochemically unresponsive. This invention presents a technique for modification of dry surfaces to render them amenable to molecular switch integration. Dry surfaces are coated with a transparent, nanoporous fiber network onto which molecular photoswitches are dispersed. Tested photoswitches demonstrated high-density loading, retained their activity, and proved stable over time. The proposed technique promises to expand the applicability of photoswitches in a broad array of functional materials including flexible substrates, as well as to enable dry surface integration of other molecular switches operating on signals other than light.
UNIVERSIDAD DE BURGOS posted this:
Revolutionary device for vertically securing hose installationResearchers from the University of Burgos have designed an innovative device for the vertical installation of hoses, specifically used by firefighting teams, with the aim of improving working conditions and reducing risks during operations. The device addresses the deficiencies and limitations of existing devices in the market. Among its advantages, it stands out for its ability to provide a secure anchoring point in various locations, its adjustable width to accommodate different hose sizes, its prevention of hose collapse, and its reduced weight for easier transportation and placement.
Osama Shabana posted this:
Revolutionizing Laparoscopic Surgery: Meet the World’s First 4K/5G Portable AI LaparoscopeWorld’s first 4K/5G wireless laparoscope: Crystal-clear imaging, zero cables, instant telemedicine collaboration. AI & AR integration: Real-time diagnostics, precision guidance, and reduced human error. Portable & cost-effective: 99% lighter, 90% cheaper zero cost to maintain—ideal for low-resource settings or on-the-go emergencies
CEO at LASCOPE
CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas posted this:
Rice husk as a filter for the removal of contaminants in waterThe CSIC, in collaboration with the Technische Universität Berlin, has developed a manufacturing process for obtaining, from rice husk, activated carbon filters for the removal of emerging organic pollutants in waters. The process, which additionally enables the recovery of an agricultural waste with null economic interest, generates filters with greater efficiency than that of the commercial activated carbons. Industrial partners are sought to collaborate through a patent licence agreement. An offer for Patent Licensing
Laser Consult Ltd.Laser Consult Ltd.Laser Consult Ltd. posted this:
RICENUT-INNO technology - A novel complex rice nutrition and conditioning processOne of our Hungarian partner company developed a complex solution to suppress pathogens and to lower dose of synthetic fertilisers and pesticides. Successful field-scale trials has demonstrated that this new generation rice-production technology is a great tool to obtain profitable yield level depending on aptitude of the production site.
Dirección de Transferencia Tecnológica (DIT) Universidad Adolfo IbáñezUniversidad Adolfo IbáñezDirección de Transferencia Tecnológica (DIT) Universidad Adolfo IbáñezAgente de Innovación at Universidad Adolfo Ibáñez
View ProfileDirección de Transferencia Tecnológica (DIT) Universidad Adolfo Ibáñez posted this:
Rich Fertilize in Siderophore, that allows to cure iron chlorosisIron deficiency in crop soil is a widespread issue that impacts plant metabolism and chlorophyll synthesis, leading to premature leaf drop and smaller fruits. This problem arises from soil conditions such as porosity and a pH level above 7, with the main symptom being leaf yellowing. While solutions exist in the market, they are expensive and difficult to implement on a large scale. However, this fertilizer utilizes Pseudomonas sp. ABC1, capable of producing pyoverdine siderophores on a larger scale. This vegetative promoting bacteria effectively addresses iron chlorosis in a cost-effective and environmentally friendly manner.
Agente de Innovación at Universidad Adolfo Ibáñez
Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRIUniversidad de Alcalá-OTRI posted this:
Risk management of the effects of solar activity: Device and procedure of obtaining in real time and high resolution, the Local Geomagnetic Disturbance at middle latitudes.The research team specialized in Space Meteorology within the Space Research Group of the University of Alcalá, has developed a device and procedure that, based on the measurement of the local geomagnetic field, is able to estimate the magnetic disturbance component associated to solar activity at middle latitudes. The determination of the magnetic disturbance component is especially relevant in cases of sporadic but explosive solar phenomena. From the perspective of the actual user, the present invention constitutes an essential element in the risk management of the effects of solar activity on vulnerable technologies, both ground-based and satellite-based (electric power, rail transport, terrestrial and positioning navigation systems, radio and satellite communication systems ...), increasing the capacities of public administrations, civil protection and emergencies and the companies themselves, in order to prepare a successful strategy for adverse conditions related to the solar activity. The group is looking for collaboration and/or commercial agreements with the Central Administration, Civil Protection, Critical Infrastructure, Electric Power companies, Rail Network, Oil pipelines companies, Gas Pipelines companies, Insurance firms, etc...
Taras MaiulaOtava Research InstituteTaras Maiula posted this:
RNA Targeted Library for post transcriptional gene regulation researches, anticancer, antiviral and antibacterial drug discovery projectsRNA is essential for transcriptional regulation, translational regulation, protein function, and catalysis, responsibilities that have classically been reserved for proteins. It also highlights the potential of targeting RNA for treatment of a multitude of diseases including bacterial/viral infection and cancer
Head of the QC department at Otava Research Institute
University of Luxembourg posted this:
RODENT PLATFORM - Luxembourg Centre for Systems BiomedicineThe new University rodent facility is a shared resource of the Luxembourg Centre for Systems Biomedicine (LCSB) and the Life Science Research Unit (LSRU) and has been established to assist researchers in the development and analysis of various in vivo models including germ-free animals.
- University of WaterlooUniversity of Waterloo
University of Waterloo posted this:
Room temperature plasmontronic devicesBackground Advances in nanotechnology science continue to support developing capabilities to finely tune, control and manipulate the properties of molecules and materials in reduced dimensions (eg. spin, anisotropy, redox potential, light, electrical field, etc) in a manner that enables the creation of new tunable semiconductor electronics including devices utilizing quantum properties. Spintronics is one such example of an emerging technique that takes advantage of electron spin properties to yield novel tunable semiconductor devices. However, a significant drawback to these devices is the need to generally operate at low temperatures. Furthermore, the sizes of potentially practical spintronic devices are limited by the critical size necessary to support long range ferromagnetic interactions (generally considered to be on the order of 100 nm). Despite much research intensity there have not yet been any broadly viable solutions to address these hurdles to more practical utilization of spintronic devices.
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Lisa Clara posted this:
S-Adenosyl-L-Homocysteine Hydrolase, Recombinant for Enhanced BioprocessingCreative Enzymes, a leading global supplier and manufacturer of quality enzymes, is thrilled to introduce the availability of Recombinant Homocysteine Methyltransferase, dedicated to assisting researchers and industrial clients to unravel the complexity of enzyme activity.
Marketing Manager at Creative Enzymes
Covid-19 Innovation Challenges by InnogetCovid-19 Innovation Challenges by InnogetCovid-19 Innovation Challenges by Innoget posted this:
S-PACES. People and vehicle monitoring IoT system to control confinement and healthcare measures during COVID-19People and vehicle monitoring IoT system to control confinement and healthcare measures during COVID-19. With this SmartCities Solution, the goal is to have a tool capable of knowing the movements of people and vehicles in different parts of the city. In this way, it will be possible to evaluate compliance with the measures adopted and implement improvements in them, if necessary.
INTEGRA posted this:
S-PACES. People and vehicle monitoring IoT system to control confinement and healthcare measures during COVID-19People and vehicle monitoring IoT system to control confinement and healthcare measures during COVID-19. With this SmartCities Solution, the goal is to have a tool capable of knowing the movements of people and vehicles in different parts of the city. In this way, it will be possible to evaluate compliance with the measures adopted and implement improvements in them, if necessary.
Yeda posted this:
Safer CAR-T cell platformChimeric Antigen Receptor (CAR)-T Cell Therapy is a personalized treatment for cancer in which the patient's T cells are genetically engineered to express a synthetic receptor that binds a tumor antigen. Although this treatment is very successful for treating some hematological cancers, it may cause a severe life-threatening side effect known as "Cytokine storm." The current technology enables the design of safer CAR-T cells with enhanced cytotoxicity and reduced cytokine release by modulating the transmembrane domain of the CAR.
Behrouz Rahimi (NU)Nu innovations IncBehrouz Rahimi (NU)Inventor-problem solver-new product-solution-economic developer at Nu innovations Inc
View ProfileBehrouz Rahimi (NU) posted this:
Safety devise for car rim -innovative designSafety for Car Rim – Device helps to keep a car and driver safe in the event that a tire is punctured or is blown; this device is replaced instead of a car’s tire, saving time and money.
Inventor-problem solver-new product-solution-economic developer at Nu innovations Inc
- Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRI
Universidad de Alcalá-OTRI posted this:
Salts of pyridazino[2,3-a]pyrrolo[2,1-c]quinoxaline for the treatment of leishmania infections and diseases that involve the protein tyrosine phosphatise 1B (metabolic syndrome, diabetes and obesity)Research groups from the Department of Organic Chemistry and Inorganic Chemistry and the Department of Systems Biology of the University of Alcalá have developed pyridazino[2,3-a]pirrolo[2,1-c]-quinoxalinium salts as therapeutic agents in the treatment of leishmaniasis, metabolic syndrome, diabetes and obesity. The compounds exhibit high activity and selectivity for the Leishmania parasite, and they provide a new therapeutic tool for the treatment of type 2 diabetes. The group seeks pharmaceutical companies to reach licensing agreements or collaboration and commercial agreements with technical assistance.![Salts of pyridazino[2,3-a]pyrrolo[2,1-c]quinoxaline for the treatment of leishmania infections and diseases that involve the protein tyrosine phosphatise 1B (metabolic syndrome, diabetes and obesity)](https://static9.innoget.com/uploads//3df023970d7a042a76c022ad05180fd34bba60d6.jpg)
Unismart - University of Padua FoundationUnismart - University of Padua FoundationUnismart - University of Padua Foundation posted this:
SAMNs Nanoparticle production for purificationThis invention has developed an innovative, environmentally sound and low-cost method for the synthesis of magnetic nanoparticles (Surface Active Maghemite Nanoparticles - SAMNs): their surface characteristics are especially useful in medical and agri-food applications.
Universitat de València posted this:
Sample collection devices of atmospheric pollutants with high performanceThe main advantages provided by the invention are: Simplicity and reproducibility in the synthesis of the new compound, due to one step synthesis process with simultaneous addition of all reagents. It isn’t necessary the removal of CDs, and it hasn’t intermediate compounds between silica and CDs. It allows the access to VOCs without any post-treatment. Adaptability of the compound to the requirements of each sample collection devices, adjusting the grain size by milling and using appropriate sieves. Procedure cleaner, safer and more economic, since it reduces the generation of toxic waste and the risk of contamination of workers. Reduce analysis time since desorption of pollutants retained in the sample collection devices can be thermal. Retention of pollutants is more independent of environmental conditions than commercial devices.Andrew Tanswell posted this:
SaniTap - a handwashing device that helps reduce the spread of COVID-19 in developing countries / refugee and IDP campsProven household handwashing device. SaniTap is designed to supply the daily handwashing requirements of a household making it an ideal tool for Covid-19 social distancing and avoiding crowding at water access points. Innovative design: No ‘second touch’ contamination (tap closes without touching of fingers). Preventing re-contamination. Collapsible design: Enables high-volume air shipping for rapid-response. Water-saving flow-control: Vital in water-scarce environments (slums, camps) 3 litres over 10 minutes, enough for a family of 5 to wash their hands 3x/day. Soap net: Soap bar doesn’t touch the floor, get lost or contaminated. Acts as a reminder to wash hands with soap. Child friendly: Weight of a full bag and and spout pull weight have been tested and designed for use by children UV resistant: Designed for tropical climates but as a food grade plastic best practice is to hang out of the sun In addition to the SaniTap logo, an area is reserved on the front for bespoke artwork, such as the distributing agency or donor logo. Pictorial instructions and guidance are displayed on the back, to aid and support behaviour change
CEO at Startle
Leading Biology posted this:
SARS-CoV-2 (2019-nCoV) Antigen ReagentIn order to better support the development and basic research of coronavirus diagnostic reagents, vaccines and therapeutic drugs, our professional R&D team has developed and produced a series of coronavirus Spike target to antigen and N protein related reagents including recombinant proteins, antibodies, antigen protein detection kits, genes, etc.
- Covid-19 Innovation Challenges by InnogetCovid-19 Innovation Challenges by Innoget
Covid-19 Innovation Challenges by Innoget posted this:
SARS-CoV-2 Helicase Targeted LibraryThe offer SARS-CoV-2 Helicase (NSP13) Targeted Library, which contain 1170 compounds with predicted activity against this vital protein. The overall procedure included accurate flexible docking of Drug-like Green Collection into helicase active site.
- Taras MaiulaOtava Research Institute
Taras Maiula posted this:
SARS-CoV-2 Helicase Targeted LibraryThe offer SARS-CoV-2 Helicase (NSP13) Targeted Library, which contain 1170 compounds with predicted activity against this vital protein. The overall procedure included accurate flexible docking of Drug-like Green Collection into helicase active site.
Head of the QC department at Otava Research Institute
- Taras MaiulaOtava Research Institute
Taras Maiula posted this:
SARS-CoV-2 Main Protease Targeted LibraryOTAVAchemicals and Montana Molecular are providing a complete solution for COVID-19 drug discovery that combines verified compound libraries with functional cell-based assays and drug development services.
Head of the QC department at Otava Research Institute
