Consejo Superior de Investigaciones Científicas posted this:Molecular Method that radically improves the diagnosis of Hereditary hemorrhagic telangiectasia (HHT)Molecular Method that radically improves the diagnosis of Hereditary hemorrhagic telangiectasia (HHT). The Granada University, Health and Progress Foundation, and the CSIC have developed a diagnostic molecular system for the HHT by getting a simple liquid biopsy from the patient. Industrial partners are being sought to collaborate through a patent license agreement to use this molecular diagnostic system with the possibility of informatics support.
Licensing Manager at uacoopera
uacoopera posted this:
Licensing Manager at uacoopera
Centre Technology Transfer CITTRU posted this:Method for conjugation of biomolecules and its new useThe subject of the offer is a novel method for conjugation of free thiol group(s) containing biomolecules comprising a biomolecule reaction with a gold-donor agent in which a -S-Au-S- bond is formed. Specifically, the method leads to a complex formation that is a protein cage. The new method comprises following steps: (i) biomolecules preparation, (ii) conjugation of biomolecules by reaction of biomolecules with gold-donor and (iii) purification of conjugation product.
Jordi Reverter posted this:
Licensing Manager at Institut Català de Nanociència i Nanotecnologia
Technology Transfer Office
Universidad de Granada posted this:Method for isolating circulating epithelial pulmonary cells and their use as markers for diagnosing Chronic Obstructive Pulmonary Disease (COPD)A procedure is described based on Liquid Biopsy techniques that allows both the diagnosis of COPD, as well as its evolution in patients. In order to do that, circulating pulmonary cells (CPCs) that could be present in blood of patients diagnosed with COPD are detected and characterized by combining two different techniques: - Immunogenetic positive selection for their isolation in peripheral blood. - Immunocytochemistry for detecting CPCs by using specific markers for pulmonary epithelial cells.
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Germans Trias i Pujol Health Sciences Research Institute posted this:Diagnostic biomarkers for dementia with Lewy BodiesThe present data provide a solid basis for the development of genetic biomarkers for the early identification of patients suffering from dementia with Lewy bodies and to classify them into specific molecular subtypes. One of the biomarkers correlates with the development of Lewy pathology in the brain and may be useful to monitor the success of possible alpha-synuclein antiaggregatory therapies.
Universidad de Alicante posted this:A decision support system for melanoma diagnosis.A Spanish Research Group has developed a system to help in the recognition of a melanoma through the visual characteristics of an image of the skin lesion. This system can be used as an automated way to decide the urgency to refer a patient to the dermatologist.
uacoopera posted this:System for the collection , storage and exhaled alveolar air conditioning for clinical analysisA group of researchers from Portuguese university developed a device that allows the collection and storage of the exhaled alveolar air by humans. The invention aims simultaneously to overcome some of the technical difficulties in the current state of the art, such as i) little or no response in the selective collection of alveolar air fraction ii) the inability to couple systems that allow concentration/extraction of analytes of interest iii) the inexistence of systems to the storage of the collected biofluid under controlled conditions and iv) the inability to collect exhaled air in liquid or vapor state. The university is looking for companies interested in the industrial production of the equipment and its commercialization.
Institute of Chemical Research of Catalonia posted this:Optical Quantification of enzymatic activity: a non-invasive diagnosis toolThe platform allows for accurate measurement of the enzymatic activity thanks to the presence of an optical signal that remains unchanged during digestion and serves as a ruler to which modifications of another signal, affected by enzymatic activity, is compared. The platform can be used in small devices, at point of care and in non-invasive diagnostic procedures. The platform is also highly versatile as a simple modification of the particle will allow using it in totally different diagnostic applications.
Centre Technology Transfer CITTRU posted this:Monoclonal antibody Miraculum for serological diagnostic in vitroNew IgG antibody suitable for specific agglutination of erythrocytes, particulary for blood typing. The unique IgG3 antibody Miraculum may be a valuable, high-quality, next generation blood typing reagent with extended shelf life. It does not lose its property after freezing. Its production is very efficient and can be more profitable compared to currently used IgM-class antibody. The invention consists in conversion of any non-agglutinating monoclonal antibody that recognizes an antigen on the surface of human erythrocytes into agglutinating molecule. The antibodies obtained in this way can be much more useful than IgM antibodies, which are currently used in agglutination assays.
Centre Technology Transfer CITTRU posted this:Anti-histidine and Anti-arginine Tag DNA aptamers for biotechnological applicationsThe subject of the offer are unique sequences of single-stranded DNA aptamers with high affinity to any molecule (peptide, protein or DNA derivative) containing His-Tag and Arg-Tag and their application in biotechnology in analysis of His-Tagged and Arg-Tagged molecules.