Yissum - Research Development Company of the Hebrew University posted this:Pepper Genome Editing-Cas9 Stable TransformationAlexander (Sasha) Vainstein - Pepper Genome Editing-Cas9 Stable Transformation (TTM# 13921) - The researcher has developed a protocol for successfully transforming sweet and hot pepper varieties to stably express the Cas9 endonuclease of the CRISPR gene editing tool. To date, no other research group has described Cas9 gene edited pepper plants. The researcher’s Cas9-pepper lines were used for genome editing via virus-driven trans-acting guides–for all the chosen target genes/traits. This innovation will allow breeders to enhance their exhisiting pepper varieties with novel traits. Furthermore, after back-crossing the lines the breeder will be able to remove the Cas9 gene leaving behind only the gene-edited pepper varieties. These resulting lines may be considered Non-GMO in certain geographies. By combining this technology with the MemoGene TTM#1705, the breeder/researcher may screen many phenotypes when transforming a plethora of guide RNAs. IP Position: Know-How Yissum Online: http://www.yissum.co.il/technologies/project/13921 Project ID : 47-2020-13921
Yissum - Research Development Company of the Hebrew University posted this:High Throughput Screening of Antimicrobial Agents Using MicrofluidicsYonatan is a Phytopathology expert using microfluidics system to do high throughput screening of libraries to identify antimicrobial agents which can be either chemical or biological (proteins or bacteria). Yonatan is testing pathogens sensitivity against combinations of bacteria and chemical agents from the libraries using the high-throughput microfluidics system. When Potential Producer, Potential Inducer have a combined affect on a Pathogen target (killing) efficiency become of interest. This is because in nature a single bacteria species is susceptible to environmental stresses but when combined with helper bacteria they support each other synergistically. Project ID : 47-2019-10825
Yissum - Research Development Company of the Hebrew University posted this:High Heat & TYLCV Resistant TomatoesHanokh Czosnek – High Heat & TYLCV Resistant Tomatoes (TTM# 10916) –The researchers used classical breeding to develop varieties of tomatoes for open field cultivation that combine resistance to TYLCV and tolerance to extreme heat reaching 45 °C. The lines show no symptoms to TYLCV with yields similar to uninfected plants and are also tolerant to heat: flowering and fruit setting routinely occur at temperatures around 40 °C. Under high temperature, the plants produce a very nice round shape fruit with average weight of 200 grams. Fruits do not show any malformation due to heat stress. Patent Position: Not Filed, Plant Breeding Rights are to be filed soon. Yissum Online http://www.yissum.co.il/technologies/project/10916 Project ID : 47-2020-10916
Yissum - Research Development Company of the Hebrew University posted this:Biologic and Genetic Marking - MemogeneAlexander (Sasha) Vainstein – MemoGene - A Viral Delivery System Platform for Enabling High Throughput Plant Genomic Modifications (TTM#1705) –MemoGene is a high throughput system for genome editing enabling fast screening for gene/trait validation, with reduced time and labor costs when compared to traditional genome editing approaches. MemoGene technology takes advantage of a Tobacco rattle virus (TRV)-based expression system, which delivers genome editing molecular tools (CRISPR/Cas compatible guide RNAs, Zinc finger nucleases and Mega nucleases) into plant cells or protoplasts and is not variety/species/genus-specific. Patent Position: https://www.lens.org/lens/patent/092-368-008-953-352 Yissum Online: http://www.yissum.co.il/technologies/project/1705 Scientific Articles: https://www.cell.com/molecular-plant/supplemental/S1674-2052(15)00198-7 http://www.plantphysiol.org/content/154/3/1079.long https://onlinelibrary.wiley.com/doi/full/10.1111/j.1467-7652.2011.00672.x Project ID : 22-2006-1705
Yissum - Research Development Company of the Hebrew University posted this:Biological Control of Biofilms With Carriers Encapsulating Microbial PredatorsAmos Nussinovitch & Edouard Jurkevitch – Biological Control of Biofilms by Carriers Encapsulating Microbial Predators– (TTM #10882) – The researchers are developing a biodegradable functional system for delivering biocontrol agents to biofilms. The carriers are made of hydrocolloids which encapsulate a high concentration of Bdellovibrio like organisms (BALOs) which are known to fight biofilms. This system is environmentally friendly, prevents the target biofilm from developing resistance and the release rate of the biocontrol agents can be controlled. Technology Concept Formulated: Seeking Sponsored Research Funding Project ID : 47-2020-10882
Yissum - Research Development Company of the Hebrew University posted this:True Potato Seeds for Potato Starch ProductionHaim Rabinowitch - True Potato Seeds For Potato Starch Production (TTM #10851) - High quality potato starch is essential and particularly valued in the food, paper, adhesives, building, and textile industries. This is due to potato starch’s unique texture, neutral taste and high clarity compared to other starches. Our researchers have developed True Potato Seeds (TPS) for the propagation of potatoes with higher starch content. Advantages of these varieties are: TPS are cheaper and easier to handle than potato tubers. Seeds do not carry over pests and disease and hence reduce losses due to viral, bacterial and fungal infections. Production costs are reduced from USD ~760/hecater when using actual tubers to USD ~435/hectare when using TPS. Our new lines have between 4-6% higher dry matter content. Therefore, the replacement of the current system of planting tubers by transplanting TPS seedlings is of a significant economic consequence. Yissum One Pager: True Potato Seeds For Potato Starch Production #10851 Project ID : 47-2020-10851
Yissum - Research Development Company of the Hebrew University posted this:Development of 2,4-D Resistant Non-Transgenic Solanaceae PlantsResearcher used transcriptomics to identify 5 crisper/cas KO targets for generating 2,4-D resistant tomatoes Project ID : 8-2016-4342
Yissum - Research Development Company of the Hebrew University posted this:Breeding Tef for Israeli ClimateA novel method to breed Teff cultivars increasing Teff productivity in conditions different from Ethiopian drought and hot climate. A Breeding Program to Maximize the Quality of Teff Cultivars Project ID : 8-2014-3050
Yissum - Research Development Company of the Hebrew University posted this:Anti-Oxidants Rich, Non-GMO TomatoesJoseph Hirschberg & Daniel Zamir - Anti-Oxidants Rich, Non-GMO Tomatoes (TTM #6744) - Tomato fruits naturally accumulate the red carotenoid pigment lycopene, our Xantomato is a novel tomato variety that accumulates high levels of the natural phytochemical zeaxanthin – instead of lycopene. The reserachers used classical genetic breeding methods to take advantage of mutations that alter carotenoid production to achieve zeaxanthin levels that are as high as 35 ?g/g FW. The zeaxanthin tomatoes will not be considered “genetically modified” (GMO), thus the fruits and extracts should face no marketing limitations. Patent Position: Provisional Filed. Scientific Article: https://www.ncbi.nlm.nih.gov/pubmed/32320515 Yissum Online: http://www.yissum.co.il/technologies/project/6744 Project ID : 8-2019-6744
Consejo Superior de Investigaciones Científicas posted this:Effective method for plant wound healingCSIC and the Center for Research in Agricultural Genomics have developed an effective method for plant tissue regeneration that involves the use of a bacterial cellulose-based biopolymer. The application of this material directly in plant wounds enhances the formation of new cells layers which boosts the healing processes. Industrial partners are being sought to exploit the existing know-how through a patent license agreement. An offer for Patent Licensing
Yissum - Research Development Company of the Hebrew University posted this:GILIS (‘280-15’) PASSION-FRUIT CULTIVAR – PINK WITH PURPLE SPOTS AND 2X BIGGER A new cultivar of passionfruit, developed by Prof. Alon Samach – 280/15 Characteristics: (1) attractive peel color red-orange (2) Pink lady/Pomegranate-like appearance (3) Large size: more than 2 –fold larger than the existent commercial varieties (4) Peel: medium thickness, allowing the firmness of the fruit without effecting the fruit content (5) Aromatic (6) Taste: sweet-sour, similar to the commercial varieties GILIS (280-15) Extra Large, Attractive Passion-Fruit Cultivar Project ID : 8-2018-4676
Yury Savinykh posted this:
Professor / PhD.
Avazyme posted this:Food safety, quality, authenticity and consulting servicesAvazyme offers agile and custom problem solving services to the food industry through the application of biological and chemical analytics. Differentiated from larger CROs that offer a rigid standardized menu of services, Avazyme is focused first on agile problem solving. Avazyme has state-of-the-art instrumentation and methodologies. Problem solving is applied to food safety, quality, authenticity and GMO testing. Avazyme also offers consulting in food regulatory science, Maximum Residue Levels (MRLs), import tolerances and food safety, quality and secondary standards, nutritional labeling, authenticity and GMO analysis. Consulting in new assay development, validation and certificate of analysis is also offered. Differentiated from larger CROs, Avazyme offers nimble, rapid and custom analytical method development and validation. Offers include development of laboratory and point of use assays. Avazyme offers organizations Independent Lab Validation (ILV). Avazyme is BSL2, EPA GLP, FDA GLP compliant and will work with companies requiring GMP and ISO17025 standards.