Centre Technology Transfer CITTRU posted this:In vivo delivery system of the DNA modifying enzymesThe subject of the offer is a new method of in vivo genome editing with the use of hybrid nucleases, such as ZFN, TALEN and the CRISPR/Cas9 system, delivered to target cells by EVs derived from stem cells in serum-free conditions and defined as the RNA-containing vesicles expressing stem cells surface markers: CD90, CD105, CD147, CD309 (in more than 20% of RNA-positive events) and lack of expression CD45.
Lidia Aguilera posted this:
Technology Transfer Officer at University of Luxembourg
Creative Biogene posted this:Human HTR2B-FLAG Stable Cell Line-CHO5-HT2B (5-hydroxytryptamine receptor 2B) is a receptor for serotonin. It is expressed in many peripheral and central nervous system tissues, including stomach fundus, liver kidney, muscle, intestine and brain. 5-HT2B receptors are responsible for many cardiovascular and central nervous system functions, such as blood vessel contraction, platelet shape changes, neuronal sensitization to tactile stimuli, and mediation of the hallucinogenic effects of phenylisopropylamin hallucinogens.
University of Vigo posted this:Method for the sequential immunochemical evaluation on a same biological sample of NCAM (Neural Cell Adhesion Molecule) protein and its PolySialic Acid (PSA) tail, by western blot coupled to chemiluminiscence detection.The method optimizes the expression assays of PSA-NCAM isoforms in biological samples available in small quantities or restricted (as is the case of human specimens, for example). It improves quantitative and qualitative performance of PSA-NCAM analysis by western blot.
Barcelona Skin Genomic posted this:Dermatological pharmaceutical composition for the treatment of skin inflammatory diseases, such as dermatitis and atopic dermatitis (Psoriasis, Acne and Itchy Skin)Dermatological formulation, composed of pharmaceutical compounds, antioxidant molecules and additional active ingredients are developed by Barcelona Skin Genomic to treat inflammatory skin diseases with high efficacy during treatment of atopic dermatitis (AD) with high Scoring Atopic Dermatitis (SCORAD) index, Psoriasis, Acne and Itchy Skin.
Barcelona Skin Genomic posted this:Recommendation of optimal combinations of natural active compounds to treat disease using a databaseBarcelona Skin Genomic (BSG) is developing a database that compiles information about the effects of different natural active compounds or plant extracts (more than 2500) on gene expression, on the levels of expression of interleukins and other molecules (more than 3400) and on treatment of different diseases (677). This database collects information from more than 5000 scientific articles, integrated by biologists and experts in life sciences and is updated on a monthly basis.
Creative Biogene posted this:Human HTR7-FLAG Stable Cell Line-HEK293TThe 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin. The 5-HT7 receptor is expressed in a variety of tissues, particularly in the brain, the gastrointestinal tract, and various blood vessels.
Creative Biogene posted this:Human P2RY2-FLAG Stable Cell Line-1321N1The P2Y2 receptor was the first of this family of receptors that can be fully activated by both ATP and UTP. P2Y2 receptors are present on all of the body"s mucosal surfaces, including the lungs, eyes, upper airways, mouth, vaginal tract and gastrointestinal tract. P2Y2 receptors have also been found on non-mucosal surfaces, such as the retinal pigment epithelium. Activation of P2Y2 has been shown to stimulate mucosal hydration and mucociliary clearance in the lungs and upper airways and induce secretion of therapeutically significant amounts of fluid and tear components to the ocular surface. Thus, P2Y2 receptors are therapeutic targets for treating serious disorders including cystic fibrosis, a fatal genetic disease, retinal detachment as well as dry eye disease.
Technology Transfer Office