Gene Expression, Proteom Research Technology Technology Offers

Lidia Aguilera posted this:
Technology Transfer Officer at University of Luxembourg

Fluorescence Assisted Genome Editing Efficient method to derive genome edited populations by the use of fluorescent markers. The Fluorescence Assisted Genome Editing technique allows deriving correctly edited clones with precision genetic modifications. Produced cells are free from non-edited, random integrations and on-target allele NHEJ-containing populations.

Fluorescence Assisted Genome Editing

Lidia Aguilera posted this:
Technology Transfer Officer at University of Luxembourg

BIOMARKER FOR PREDICTION OF RECURRENCE IN COLORECTAL CANCER PATIENTS Approximately 20% of colorectal cancer patients with stage II colorectal cancer experience relapse of the disease. Current clinical-pathologic stratification factors do not allow clear identification of these high-risk patients. The invention is a powerful prognostic biomarker in colorectal cancer, especially in early stages (stages I and II), which might help stratifying patients with stage II for adjuvant chemotherapy. The invention provides a gene expression classifier that distinguishes patients with low or high risk of disease relapse in colorectal cancer and that might be used in the clinics to help clinicians identify high-risk patients and choose the most appropriate treatment for a given patient.

BIOMARKER FOR PREDICTION OF RECURRENCE IN COLORECTAL CANCER PATIENTS

Centre Technology Transfer CITTRU posted this:

In vivo delivery system of the DNA modifying enzymes The subject of the offer is a new method of in vivo genome editing with the use of hybrid nucleases, such as ZFN, TALEN and the CRISPR/Cas9 system, delivered to target cells by EVs derived from stem cells in serum-free conditions and defined as the RNA-containing vesicles expressing stem cells surface markers: CD90, CD105, CD147, CD309 (in more than 20% of RNA-positive events) and lack of expression CD45.

In vivo delivery system of the DNA modifying enzymes

Lidia Aguilera posted this:
Technology Transfer Officer at University of Luxembourg

AQUATIC PLATFORM - Luxembourg Centre for Systems Biomedicine The LCSB Aquatic Platform is centred around the use of zebrafish (Danio rerio), a vertebrate model with high genetic and physiologic similarity to humans. This versatile, reliable model organism is widely used for the in vivo study of developmental biology, gene function, drug discovery and pathophysiological aspects of various human diseases such as epilepsy, rare diseases, neurodegenerative disorders, among others.

AQUATIC PLATFORM - Luxembourg Centre for Systems Biomedicine

Creative Biogene posted this:

Human HTR2B-FLAG Stable Cell Line-CHO 5-HT2B (5-hydroxytryptamine receptor 2B) is a receptor for serotonin. It is expressed in many peripheral and central nervous system tissues, including stomach fundus, liver kidney, muscle, intestine and brain. 5-HT2B receptors are responsible for many cardiovascular and central nervous system functions, such as blood vessel contraction, platelet shape changes, neuronal sensitization to tactile stimuli, and mediation of the hallucinogenic effects of phenylisopropylamin hallucinogens.

Human HTR2B-FLAG Stable Cell Line-CHO

University of Vigo posted this:

Method for the sequential immunochemical evaluation on a same biological sample of NCAM (Neural Cell Adhesion Molecule) protein and its PolySialic Acid (PSA) tail, by western blot coupled to chemiluminiscence detection.The method optimizes the expression assays of PSA-NCAM isoforms in biological samples available in small quantities or restricted (as is the case of human specimens, for example). It improves quantitative and qualitative performance of PSA-NCAM analysis by western blot.

Barcelona Skin Genomic posted this:

Dermatological pharmaceutical composition for the treatment of skin inflammatory diseases, such as dermatitis and atopic dermatitis (Psoriasis, Acne and Itchy Skin)Dermatological formulation, composed of pharmaceutical compounds, antioxidant molecules and additional active ingredients are developed by Barcelona Skin Genomic to treat inflammatory skin diseases with high efficacy during treatment of atopic dermatitis (AD) with high Scoring Atopic Dermatitis (SCORAD) index, Psoriasis, Acne and Itchy Skin.

Dermatological pharmaceutical composition for the treatment of skin inflammatory diseases, such as dermatitis and atopic dermatitis (Psoriasis, Acne and Itchy Skin)

Barcelona Skin Genomic posted this:

Recommendation of optimal combinations of natural active compounds to treat disease using a database Barcelona Skin Genomic (BSG) is developing a database that compiles information about the effects of different natural active compounds or plant extracts (more than 2500) on gene expression, on the levels of expression of interleukins and other molecules (more than 3400) and on treatment of different diseases (677). This database collects information from more than 5000 scientific articles, integrated by biologists and experts in life sciences and is updated on a monthly basis.

Creative Biogene posted this:

Human HTR7-FLAG Stable Cell Line-HEK293T The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin. The 5-HT7 receptor is expressed in a variety of tissues, particularly in the brain, the gastrointestinal tract, and various blood vessels.

Human HTR7-FLAG Stable Cell Line-HEK293T

Creative Biogene posted this:

Human P2RY2-FLAG Stable Cell Line-1321N1 The P2Y2 receptor was the first of this family of receptors that can be fully activated by both ATP and UTP. P2Y2 receptors are present on all of the body"s mucosal surfaces, including the lungs, eyes, upper airways, mouth, vaginal tract and gastrointestinal tract. P2Y2 receptors have also been found on non-mucosal surfaces, such as the retinal pigment epithelium. Activation of P2Y2 has been shown to stimulate mucosal hydration and mucociliary clearance in the lungs and upper airways and induce secretion of therapeutically significant amounts of fluid and tear components to the ocular surface. Thus, P2Y2 receptors are therapeutic targets for treating serious disorders including cystic fibrosis, a fatal genetic disease, retinal detachment as well as dry eye disease.

Human P2RY2-FLAG Stable Cell Line-1321N1

Creative Biogene posted this:

Human HTR2C-FLAG Stable Cell Line-CHO 5-HT2C (5-hydroxytryptamine receptor 2C) is a receptor for serotonin. It is expressed in the brain and spinal cord, especially the choroid plexus.

Human HTR2C-FLAG Stable Cell Line-CHO

RAMOT at Tel Aviv University Ltd. posted this:

Large Scale Computational Methods for Calculating Energies and Energy Densities of Large Systems Large Scale Computational Methods for Calculating Energies and Energy Densities of Large Systems Project ID : 4-2013-702