a a
l l
CSIC, University of Zaragoza and Technische Universität Dresden
have developed an enzymatic
composition and its use as an enzymatic cascade for the production of 2,5-furandicarboxylic acid
(FDCA) from 5-methoxymethylfurfural (MMF). This cascade is self-sustained with the only consumption
of atmospheric oxygen and the MMF itself. The method can be applied to the conversion of MMF into
FDCA step in the bioplastic producing industry, switching from the current inorganic catalysts
employed to the use of enzymes for the FDCA production.
Industrial partners are being sought to develop and commercialize the enzymatic composition through
a patent licence agreement.
An offer for Patent Licensing
A self-sustained enzymatic cascade reaction
Use of the enzymatic composition for the production of 2,5-furandicarboxylic acid (FDCA) from 5-methoxymethylfurfural (MMF) Nowadays, there is an increase in the need of the substitution of petroleum-based materials with renewable ones. In this regard, FDCA is a promising precursor for the production of renewable and biodegradable bioplastics. FDCA can be obtained from 5-hydroxymethylfurfural (HMF) through the acidic dehydration of fructose, but MMF represents a promising alternative to HMF.
The use of enzymes for the production of FDCA is interesting to substitute the current methods based on chemical catalysts and acid-containing solvents such as acetic acid dilutions.
The procedure developed uses the novel enzymatic composition for the bioconversion of plant-derived, thus, renewable, MMF into FDCA by enzymatic catalysts that only consumes atmospheric oxygen and that can be carried out at room temperature and atmospheric pressure. The MMF is obtained by the acidic dehydration of lignocellulose-derived fructose in the presence of methanol and is supposed to exhibit better storage stability than HMF. It can be used in the industrial production of polyethylene furandicarboxylates (PEFs) using enzymes for FDCA production instead of inorganic catalysts.
Main innovations and advantages
· The method described does not use inorganic catalysts, but enzymesthat accomplish their tasks synergistically at room temperature andatmospheric pressure.
· The method saves energy in comparison with the current techniques,which rely on high temperatures for the production of FDCA, and isenvironmentally-friendly.
The Spanish National Research Council (in Spanish 'Consejo Superior de Investigaciones Científicas (CSIC)') is a government agency for basic and applied scientific research.
It is the largest public research organization in Spain, with presence in all the Autonomous Communities through 126 centers and 145 associated units.
Create your free account to connect with CSIC - Consejo Superior de Investigaciones Científicas and thousands of other innovative organizations and professionals worldwide
Send a request for information
to CSIC - Consejo Superior de Investigaciones Científicas
Technology Offers on Innoget are directly posted
and managed by its members as well as evaluation of requests for information. Innoget is the trusted open innovation and science network aimed at directly connect industry needs with professionals online.
Need help requesting additional information or have questions regarding this Technology Offer?
Contact Innoget support
