An electrical stable electrochemical sensor device based on Electrolyte-Gated Field-Effect Transistor (EGFET)

Posted by Alfonso from ICMAB-CSICResponsive · Patents for licensing · Spain

Summary of the technology

A Spanish research institution has developed an Electrolyte-Gated Field-Effect Transistor (EGFET) with enhanced electrical stability. These new EGFETs operate in an aqueous environment, and are stable for more than 12 hours under uninterrupted operation, greatly surpassing current state-of-the-art EGFETs. The increased stability makes them suitable for real-life applications


Description of the technology

A Spanish Research Institution has developed an Electrolyte-Gated Field-Effect Transistor EGFET) with enhanced electrical stability. The inventors have expertise in molecular and flexible electronics.

Point-of-Care (POC) biosensors or environmental portable sensors facilitate early diagnostic and analysis outside laboratories. Those sensors are based on different technologies among them, electrochemical sensors, such as Electrolyte-Gated Field-Effect Transistors (EGFETs). EGFETs are highly sensitive, with low production cost and low energy consumption, and are compatible with flexible substrates. Importantly, EGFETs can be exposed directly to aqueous media needing less sample treatment. Unfortunately, EGFETs have limited electrical stability, less than an hour in continuous operation, due to the poor stability of the active semiconducting layer in contact with water molecules, making its real-life application difficult.

The present EGFET has increased electrical stability. A new protective layer, placed between the aqueous media and the active layer, greatly increases the devices electrical stability which typically degrades within an hour to successfully operate uninterruptedly for more than 12 hours.

This new device can then be applied for the label-free detection of analytes in aqueous media with few preparation/concentration of the samples. Samples can be among others: water samples, biological liquid samples, etc. The sensor can also be inserted into a microfluidic circuit in order to achieve a compact device that only requires a very small sample volume.

Advantages and innovations:

  • New EGFEt design that increases stability in aqueous media. Uninterrupted operation for more than 12 hours.
  • New EGFETs can be produced with different methods, including techniques compatible with roll-to-roll processes.
  • Label-free and high sensitive detection.
  • Potential for sensing applications in aqueous media, such as the detection of ions or bio-molecules.

Current development status

Laboratory prototypes


Point-of-care biosensors environmental sensors

Desired business relationship

Patent licensing

Technology development

Intellectual property status

Patent already applied for

Technology Owner


Research Institute

Additional information (attached documents)

Related keywords

  • Electronics, IT and Telecomms
  • Electronics, Microelectronics
  • Electronic circuits, components and equipment
  • Biosensor
  • Biological Sciences
  • Medicine, Human Health
  • Diagnostics, Diagnosis
  • Heart and blood circulation illnesses
  • Micro- and Nanotechnology related to Biological sciences
  • Ionic Liquids
  • Sensors & Wireless products
  • Food Microbiology / Toxicology / Quality Control
  • Micro- and Nanotechnology related to agrofood
  • Measurements and Standards
  • Measurement Tools
  • Analyses / Test Facilities and Methods
  • Electrical Technology related to measurements
  • Sensor Technology related to measurements
  • Electronic measurement systems
  • Medical Health related
  • Diagnostic
  • Diagnostic services
  • In-vitro diagnostics
  • transistor
  • electrochemical sensor


Research Institute from Spain

Spanish Research Institute focused on the development of new materials

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