Method for the diagnosis of arthrosis
Patents for licensing
Never miss an update from CINBIO
Create your free account to connect with CINBIO and thousands of other innovative organizations and professionals worldwide
Technology Offer
Method for the diagnosis of arthrosis
- CINBIO
- From Spain
- Responsive
- Patents for licensing
Summary of the technology
Arthrosis is a rheumatic pathology that damages articular cartilage. Is not hereditary, as there is no fixed hereditary pattern. Currently, the diagnosis is based on the evaluation of the symptoms and the physical examination of the patients by the physicians. Significant progress is being made in the study of the so-called biological markers of arthrosis. These are products released from the articular cartilage into the synovial fluid, the urine or the blood during the synthesis and destruction of the cartilage, which would allow for a better diagnosis and earlier intervention in the treatment of the disease.
The present invention relates to a peptide pattern characteristic of subjects who suffer from arthrosis and it also relates to an in vitro diagnostic method and the use of a kit.
Details of the Technology Offer
The authors started with serum samples from patients diagnosed with arthrosis and performed a chemical depletion in order to subsequently perform a tryptic digestion. Thereafter, the resulting peptides were retained. Finally, each eluted fraction was analysed in quintuplicate to obtain the masses of the peptides characteristic of the peptide pattern present in subjects who suffer from arthrosis. The subsequent validation of the peptide pattern obtained confirmed the utility of this pattern for the diagnosis of arthrosis.
Applications
Description of a peptide pattern present in subject who suffer from arthrosis, not present in healthy subjects or in subjects who suffer another type of rheumatic disease.
Intellectual property status
- Granted Patent
- Patent application number :EP3236263
https://worldwide.espacenet.com/patent/search/family/055629465/publication/EP3236263A1?q=EP3236263
- Granted Patent
- Patent application number :ES2568702
https://worldwide.espacenet.com/patent/search/family/055629465/publication/ES2568702A1?q=pn%3DES2568702A1
Related Keywords
About CINBIO
CINBIO is a multidisciplinary research centre in the field of nanomaterials and biomedicine. Top level researchers in disciplines as varied as medicine, biology, chemistry, physics, mathematics and information technology make up our staff.
Our fundamental objective is to have a multiplier effect on society and give back highly-specialised professionals, scientific knowledge and transfer our research results to the market.
It is CINBIO's goal to consolidate, through excellence and a more direct response to the needs of society, as a reference centre for innovation in the fields of biotechnology and biomedicine.
Related Technology Offers
Send a request for information
to CINBIO
About Technology Offers
Technology Offers on Innoget are directly posted
and managed by its members as well as evaluation of requests for information. Innoget is the trusted open innovation and science network aimed at directly connect industry needs with professionals online.
Help
Need help requesting additional information or have questions regarding this Technology Offer?
Contact Innoget support
