Covid-19 Innovation Challenges by Innoget

SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library

Posted by Covid-19 Innovation Challenges by InnogetVery responsive · Innovative Products and Technologies · United Kingdom

Summary of the technology

OtavaResearch Institute group presents SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library (1031 in-stock compounds with predicted activity against SARSCoV2 (RdRpp)).

Covid-19 Innovation Challenges by Innoget

Description of the technology

Since RNA-dependent RNA polymerase is an important enzyme that catalyzes the replication of RNA from RNA template . TheSARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library has been designed with receptor-based virtual screening The designed SARS-CoV-2 RdRp Targeted Library comprises only drug-like compounds (PAINS compounds are filtered off).

Final selection of compounds was made with inspection of enzyme active site’s crucial structural determinants for ligand binding, docking scores and intermolecular hydrogen bonds with key active site’s amino acid residues. The library is intended for screening projects to find new compounds with activity against SARS-CoV-2.

Technology Owner

Covid-19 Innovation Challenges by Innoget

Innovation Intermediary

Related keywords

  • Applications for Health
  • Biological Sciences
  • Medicine, Human Health
  • Biostatistics, Epidemiology
  • Clinical Research, Trials
  • Virus, Virology / Antibiotics / Bacteriology
  • Emergency Medicine Technology
  • Biology / Biotechnology
  • Enzyme Technology
  • Industrial Biotechnology
  • Infectious Diseases
  • Emergency medicine Market
  • Covid-19
  • library
  • sars-cov-2
  • rna polymerase
  • compounds library

About Covid-19 Innovation Challenges by Innoget

Innovation Intermediary from United Kingdom

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Channeled through Innoget's online open innovation network, initiatives in the health, virology, medicine, or novel technologies applied to human health, among others, are listed and disseminated to Innoget members -ranging from hospitals, research institutes, scientists, businesses, and public administrations- and innovation partners worldwide.