Otava Research Institute

SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library

Posted by Nadiia from Otava Research InstituteResponsive · Innovative Products and Technologies · Ukraine

Summary of the technology

OtavaResearch Institute group presents SARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library (1031 in-stock compounds with predicted activity against SARSCoV2 (RdRpp)).

Otava Research Institute

Description of the technology

Since RNA-dependent RNA polymerase is an important enzyme that catalyzes the replication of RNA from RNA template . TheSARS-CoV-2 RNA-dependent RNA Polymerase Targeted Library has been designed with receptor-based virtual screening The designed SARS-CoV-2 RdRp Targeted Library comprises only drug-like compounds (PAINS compounds are filtered off).

Final selection of compounds was made with inspection of enzyme active site’s crucial structural determinants for ligand binding, docking scores and intermolecular hydrogen bonds with key active site’s amino acid residues. The library is intended for screening projects to find new compounds with activity against SARS-CoV-2.

Technology Owner

Otava Research Institute

Research Institute

Related keywords

  • Biological Sciences
  • Medicine, Human Health
  • Virus, Virology / Antibiotics / Bacteriology
  • Biology / Biotechnology
  • Enzyme Technology
  • Infectious Diseases
  • Applications for Health
  • Emergency Medicine Technology
  • Industrial Biotechnology
  • E-Health
  • Biostatistics, Epidemiology
  • Medical Health related
  • Medical/health
  • Covid-19
  • rna polymerase
  • library
  • compounds library
  • sars-cov-2

About Otava Research Institute

Research Institute from Ukraine

Otava Institute is a global provider of one-stop integrated research solutions for business and life science. Our team includes chemists, biologists, physicists whose combined efforts contribute to the complex contract research projects for pharmaceutical, agro, cosmetic and material science industries.We are dedicated to providing clients with outstanding service in these key areas and will continue to push boundaries to remain an industry front-runner. Each day we expand our core competencies delivering of new technologies to meet all the customer’s needs.

Our location in Toronto Ontario, Canada provides our clients with the added advantage of North American IP rules and regulations and secure communication and logistics. Our Ukraine – based R&D facilities represented with the Ukrainian Laboratories, that is cooperating with leading Ukrainian research institutions and carries out research work in the format of outsourcing.

We work as a preferred partner to many of the world’s top 10 pharma firms, and hundreds of other companies, providing support with creative solutions for complex technical compound issues. Our scientific knowledge, combined with our research and manufacturing capability, enables us to support chemical processing and production without ever compromising on quality.

Our experience, dedication, and commitment to quality make us an ideal partner for discovery stage research.

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