Covid-19 Innovation Challenges by Innoget

SARS-CoV-2 Papain-like ProteaseTargeted Library

Posted by Covid-19 Innovation Challenges by InnogetVery responsive · Innovative Products and Technologies · United Kingdom

Summary of the technology

Using receptor based virtual screening OtavaResearchInstitute’s team designed the SARS-CoV-2 Papain-like Protease PLpro Targeted Library, which is contain 1058 stock compounds with predicted activity against this protease and ready for delivery.

Covid-19 Innovation Challenges by Innoget

Description of the technology

The papain-like protease PLpro is required for coronaviral replication as a part of NSP3 multi-domain protein. The ubiquitin and ISG15 PLpro are removed from the host cell proteins to prevent coronaviruses the formation of innate immune reactions. OtavaResearchInstitute’s team designed the SARS-CoV-2 Papain-like Protease PLpro Targeted Library (1058 stock compounds) using receptor based virtual screening.
The designed SARS-CoV-2 Papain-like Protease Targeted Library comprises only druglike compounds without PAINS compounds. The library is intended for screening projects to find new compounds with activity against SARS-CoV-2.
Feel free to contact us directly

Technology Owner

Covid-19 Innovation Challenges by Innoget

Innovation Intermediary

Related keywords

  • Applications for Health
  • Biological Sciences
  • Medicine, Human Health
  • Biostatistics, Epidemiology
  • Medical Research
  • Human vaccines
  • Emergency Medicine Technology
  • Biology / Biotechnology
  • Industrial Biotechnology
  • Infectious Diseases
  • Medical/health
  • Medical Health related
  • Diagnostic
  • Diagnostic services
  • Covid-19
  • coronavirus
  • sars-cov-2

About Covid-19 Innovation Challenges by Innoget

Innovation Intermediary from United Kingdom

Ahead of the current Coronavirus outbreak, Innoget is fully committed to contributing to mobilizing scientific and expert communities to find a real solution to the Covid-19 pandemic. Therefore, we're supporting worldwide calls and programs that could help in any aspects of the coronavirus crisis.

Is your organization promoting or looking for innovation or research initiatives to mitigate the Covid-19 outbreak? Email us at covid19@innoget.com to list them.

Channeled through Innoget's online open innovation network, initiatives in the health, virology, medicine, or novel technologies applied to human health, among others, are listed and disseminated to Innoget members -ranging from hospitals, research institutes, scientists, businesses, and public administrations- and innovation partners worldwide.