- Increased blood vessel permeability and vascular leak are a final common pathway in severe influenza and other fatal diseases, such as MERS, Ebola, Coronavirus and sepsis.
- We have developed at the Hebrew U.- Hadassah Medical School( Prof. Shmuel (Muli) Ben-Sasson and his colleagues a novel biologics that tightens blood vessels and prevents vascular-leak related death.
- Drug characterization and mode of action (MoA): The drug is a novel short peptide (only 5 amino acids in length), including several chemical modifications. This biologics was rationally designed to abrogate vascular permeability, based on molecular insights we gained. Its efficacy was demonstrated in a mouse model of sepsi.
VP, Business Development, Healthcare
HUJI, School of Medicine - IMRIC
Developmental Biology and Cancer Research