Yissum - Research Development Company of the Hebrew University

A Unique Platform for Curing Coronavirus and Similar Lethal Diseases

Posted by Yissum - Research Development Company of the Hebrew UniversityResponsive · Innovative Products and Technologies · Israel

Summary of the technology

A Unique Platform for Curing Coronavirus and Similar Lethal Diseases
Project ID : 47-2020-10878

Yissum - Research Development Company of the Hebrew University

Description of the technology

  • Increased blood vessel permeability and vascular leak are a final common pathway in severe influenza and other fatal diseases, such as MERS, Ebola, Coronavirus and sepsis.
  • We have developed at the Hebrew U.- Hadassah Medical School( Prof. Shmuel (Muli) Ben-Sasson and his colleagues a novel biologics that tightens blood vessels and prevents vascular-leak related death.
  • Drug characterization and mode of action (MoA): The drug is a novel short peptide (only 5 amino acids in length), including several chemical modifications. This biologics was rationally designed to abrogate vascular permeability, based on molecular insights we gained. Its efficacy was demonstrated in a mouse model of sepsi.

Project manager

Keren-Or Amar
VP, Business Development, Healthcare

Project researchers

Shmuel Ben-Sasson
HUJI, School of Medicine - IMRIC
Developmental Biology and Cancer Research

Hadas Reuveni
HUJI,

Related keywords

  • Infectious Diseases
  • Virus, Virology / Antibiotics / Bacteriology
  • Biological Sciences
  • Medicine, Human Health
  • Covid-19
  • Genetic Engineering / Molecular Biology
  • Medical Health related
  • Therapeutic
  • In vitro Testing, Trials Market
  • covid-19
  • coronavirus

About Yissum - Research Development Company of the Hebrew University

Technology Transfer Office from Israel

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Founded in 1964 to protect and commercialize the Hebrew University’s intellectual property. Ranked among the top technology transfer companies, Yissum has registered over 8,900 patents covering 2,500 inventions; has licensed out 800 technologies and has spun-off 90 companies. Products that are based on Hebrew University technologies and were commercialized by Yissum generate today over $2 Billion in annual sales.

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