Procedure for the deoxygenation of sulfoxides quickly, efficiently and sustainably

  • From Spain
  • Responsive
  • Patents for licensing

Summary of the technology

Researchers from the University of Burgos have developed a methodology for the deoxygenation of sulfur compounds (sulfoxides). To carry out this transformation, natural compounds from the biomass and a molybdenum catalyst are used. The products are obtained with high yields and high purity.


Details of the Technology Offer

New and innovative aspects

The reduction of sulfoxides (1) to the corresponding sulfides (2) is a very useful transformation both in the chemical industry and in the pharmaceutical industry.

There are several methods to carry out this transformation, however, the procedure patented by the University of Burgos allows obtaining these compounds quickly, efficiently and and sustainably, using a novel reducing agent and a molybdenum catalyst. The reaction conditions make the purification of the final compounds extremely easy.

Main advantages of its use

The main advantages of this method are the following:
- Use of natural compounds, monoterpenes from biomass, environmentally benign and sustainable.
- Monoterpenes act as a solvent, reducing costs and their by-products can be easily removed.
- The products are obtained with yields greater than 75% and high purity.
- The transformation does not require an inert atmosphere and is completed in two hours by heating to 160 ºC.
- High tolerance of functional groups.


The monoterpenes obtained from the biomass are used in equimolar amounts, acting both as reducing agents and the solvent. The dioxomolybdenum (VI) compound, MoO2Cl2(dmf)2, is added in catalytic amounts (5 mol%) and is responsible for accelerating and facilitating the process.
The by-products obtained in the reaction are p-cymene and water, which allows the purification of the deoxygenated product quickly and easily, without the need to resort to complex separation techniques.
The low toxicity of the reagents used allows the reaction to be carried out with a higher degree of safety and from a more environmentally friendly point of view.


This technology has direct application in the chemical industry and the pharmaceutical industry.

Intellectual property status

- Protected by a patent P202330200

Current development status

- Prototype available for demonstration.

Desired business relationship

- Trade Agreement, License Agreement, Technical cooperation: further development, Technical Cooperation: testing of new applications; Technical Cooperation: adaptation to specific needs.

Intellectual property status

Related Keywords

  • Physical Sciences and Exact Sciences
  • Other
  • catalysis
  • reduction
  • Sulfoxide
  • sulfide
  • deoxygenation
  • γ-terpinene
  • monoterpene


The aim of the The Technology Transfer Office (TTO) of the Univesidad de Burgos is to promote Innovation technology through the reseach results transfer and the conexions between the University and the new needs and requirements of the society - we are the link between the University and the Industry. Contact person: José Manuel López (


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