Covid-19 Innovation Challenges by Innoget

Screening of Drugs to Inhibit Viral Infections

Posted by Covid-19 Innovation Challenges by InnogetVery responsive · Innovative Products and Technologies · United Kingdom

Summary of the technology

Our group has published a lot of work on the SARS Coronavirus. We were the first to characterize an important protein in the virus that has a very unusual structure and sequence (E protein). Moreover, this protein was unique to SARS and was not found in any other Coronavirus. Now importantly, the new 2019 Coronavirus has a very similar protein!

Project ID : 47-2020-10879

Covid-19 Innovation Challenges by Innoget

Description of the technology

  • Our group has published a lot of work on the SARS Coronavirus. We were the first to characterize an important protein in the virus that has a very unusual structure and sequence (E protein). Moreover, this protein was unique to SARS and was not found in any other Coronavirus. Now importantly, the new 2019 Coronavirus has a very similar protein!
  • Researches shown that the SARS protein may impact the membrane stability due to membrane hydrophobic mismatch. It may also be an ion channel. This is good news since ion channels make very good drug targets. We have already cloned the protein from the 2019 coronavirus and showed that it is an ion channel as well. After that, we will make use of several different assays that we have developed to screen for drugs that may inhibit this channel and consequently the virus.

Project manager

Mel Larrosa
VP Business Development Healthcare

Project researchers

Isaiah Arkin
HUJI, Faculty of Science
The Alexander Silberman Institute for Life Sciences

Technology Owner

Covid-19 Innovation Challenges by Innoget

Innovation Intermediary

Related keywords

  • Biological Sciences
  • Virus, Virology / Antibiotics / Bacteriology
  • Infectious Diseases
  • Genetic Engineering / Molecular Biology
  • Covid-19
  • screening

About Covid-19 Innovation Challenges by Innoget

Innovation Intermediary from United Kingdom

Ahead of the current Coronavirus outbreak, Innoget is fully committed to contributing to mobilizing scientific and expert communities to find a real solution to the Covid-19 pandemic. Therefore, we're supporting worldwide calls and programs that could help in any aspects of the coronavirus crisis.

Is your organization promoting or looking for innovation or research initiatives to mitigate the Covid-19 outbreak? Email us at covid19@innoget.com to list them.

Channeled through Innoget's online open innovation network, initiatives in the health, virology, medicine, or novel technologies applied to human health, among others, are listed and disseminated to Innoget members -ranging from hospitals, research institutes, scientists, businesses, and public administrations- and innovation partners worldwide.

Technology Offers on Innoget are directly posted and managed by its members as well as evaluation of requests for information. Innoget is the trusted open innovation and science network aimed at directly connect industry needs with professionals online.