Consejo Superior de Investigaciones Científicas

Microorganism and method to produce urolithins

Posted by Consejo Superior de Investigaciones CientíficasResponsive · Patents for licensing · Spain

Summary of the technology

Professor Francisco Tomas group at CEBAS-CSIC has isolated and characterized the first urolithins-
producing microorganism from ellagic acid and ellagitannins present in the diet. A urolithin producing
method based on the use of the mentioned microorganism has been developed and both, the
microorganism and the method are part of a Spanish priority patent application assigned to CSIC.

Biotech companies, functional food or nutraceutical companies are sought for license and/or
development agreements.

An offer for Patent Licensing

Consejo Superior de Investigaciones Científicas

Antioxidant activity


Urolithins production as in the intestine Urolithins are antioxidant compounds that could act as estrogenic modulators, have anti-inflammatory and anticancer activities, prebiotic effects and prevention of cardiovascular diseases.
The microbes present in the intestine through dietary ellagic acid and ellagitannins metabolism produce these compounds. The urolithins produced, once absorbed, join the blood current and could exert their protecting effect in the corresponding organ/tissue.
The invention provides a microorganism capable to produce urolithins from dietary ellagic acid and ellagitannins. Besides, a method for industrial production of urolithins to be used in food compositions, drinks, dietary complements, pharmaceutical compositions and/or functional foods enriched in urolithins produced in a similar form as in the intestine (bacterial metabolism from dietary polyphenols) has been developed.

Main innovations and advantages


· The first described and characterized microorganism able to produceurolithins.
· Method for industrial production of urolithins for various uses aspharmaceutical, food, drink, etc.
· Urolithins producing microorganism identification system.

Intellectual property status

Granted Patent
-
Spanish patent granted

Granted Patent
-
Spanish patent granted

Technology Owner

Consejo Superior de Investigaciones Científicas

Public Agency

Related keywords

  • Electronics, IT and Telecomms
  • Biological Sciences
  • Biology / Biotechnology
  • Agrofood Industry
  • Technologies for the food industry
  • Medical Health related
  • Agro and Marine biotech
  • Foodstuffs Intended For Special Nutritional Uses
  • nutraceuticals

About Consejo Superior de Investigaciones Científicas

Public Agency from Spain

The Spanish National Research Council (in Spanish 'Consejo Superior de Investigaciones Científicas (CSIC)') is a government agency for basic and applied scientific research.

It is the largest public research organization in Spain, with presence in all the Autonomous Communities through 126 centers and 145 associated units.

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