Yissum - Research Development Company of the Hebrew University

A New Ophthalmic Viscoelastic Device (OVD) for Cataract Surgery

Posted by Yissum - Research Development Company of the Hebrew UniversityResponsive · Innovative Products and Technologies · Israel

Summary of the technology

Project ID : 7-2010-2523

Yissum - Research Development Company of the Hebrew University
Yissum - Research Development Company of the Hebrew University

Description of the technology

Dr. Yaacov Rozenman, Head of Shaarei Tzedek’s Ophthalmology Department


  • A cataract pathology causes the partial or entire lens clouding inside the eye, resulting in blurred or distorted vision. Cataract retrieval surgery is one of the most frequent medical procedures performed in the world.
  • A phacoemulsification technique utilizes high-intensity ultrasound energy for the fragmentation and emulsification of the cataractous lens. The procedure is traumatic to the tissues surrounding the anterior chamber. There is a need to protect the endothelial cells during cataract surgeries

Our Innovation

The researchers developed a “Smart” Ophthalmic Viscoelastic Device employing thermo-responsive polymeric system. The OVD is injected to the anterior chamber in a capsular bag. The OVD creates space between the lens and the corneal endothelial cells constituting a physical barrier. The OVD remains in place as clear gel throughout the surgery, to support and protect the cornea. At the end of the surgery, the OVD is easily removed through a small bore needle.


  • Bio-available, nontoxic to ocular tissues, mainly to the endothelial cell layer
  • Rapid and straightforward procedure
  • Does not damage the endothelium mechanically

Project manager

Mel Larrosa
VP Business Development Healthcare

Project researchers

Daniel Cohn
HUJI, Faculty of Science
The Institute of Chemistry

Related keywords

  • Clean Industrial Technologies
  • Biological Sciences
  • Medicine, Human Health
  • Other (uncategorised)
  • Medical instruments
  • Medical equipment
  • Genetic Engineering / Molecular Biology
  • Life Science & Biotechnology

About Yissum - Research Development Company of the Hebrew University

Technology Transfer Office from Israel

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Founded in 1964 to protect and commercialize the Hebrew University’s intellectual property. Ranked among the top technology transfer companies, Yissum has registered over 8,900 patents covering 2,500 inventions; has licensed out 800 technologies and has spun-off 90 companies. Products that are based on Hebrew University technologies and were commercialized by Yissum generate today over $2 Billion in annual sales.

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