New phenolic natural extract obtained from olive and herbal spices with proven cardioprotective effect.

Summary of the technology

This product consists of a natural extract wich combines olive oil phenols and other bioactive compounds from herbal species. The bioactive compounds of the natural extract have been characterized and quantified. Its use allows a novel therapeutic approach by means of the combination of complementary antioxidants from different origins that provides additional health benefits. Consumer acceptance has previously been assessed by conducting a panel test. Data from a randomized, controlled, crossover, clinical trial showed an improvement of vivo endothelial function and HDL subclass distribution, in humans. These effects were obtained with a low daily intake of the extract.

Description of the technology

The proposed technology consists of a natural extract with proven cardioprotective effects. The extract is enriched with phenols of olive origin and supplemented with bioactive compounds of herbal spices from the Labieate family. Its use in the food industry, as a product itself or as an ingredient for food formulations, will enable the development of new foods with cardioprotective effects which can be consumed in the context of a balanced diet and by the general population. Collaboration with industrial partners, food companies, or ingredient manufacturers in order to complete the development of a commercial product and/or for the adaptation to specific needs are being sought.


This phenol-enrich the new ingredient is based on natural extracts from edible herbal spices of Labiatae family and from olive cake. It is obtained by accelerated solvent extraction in ethanol/water and at high temperature and pressure conditions. Bioactive compounds have been characterized and quantified and a standardized content is assured.

Main advantages of its use

  • Bioactive compounds have been characterized and quantified and a standardized content is assured.


  • Emulsions and water contained systems. Dressings and spreads. Olive oil, vegetal oils, and systems of low water content. Dietary supplements and nutraceuticals.

Related Keywords

  • Technologies for the food industry
  • Food Additives/Ingredients/Functional Food
  • Food Technology
  • Drink Technology
  • Medical Health related
  • Food and feed ingredients
  • Health food
  • Foodstuffs Intended For Special Nutritional Uses
  • Cardioprotective effects
  • extract phenol-enrich
  • bioactive compounds
  • herbal species.

About IMIM Institut Recerca Hospital del Mar

IMIM (Hospital del Mar Medical Research Institute), located at the Barcelona Biomedical Research Park (PRBB) is, up to 82%, made up of research groups lead by professionals from the MAR Health Park , most of whom are associates of the Autonomous University of Barcelona (UAB) and the Pompeu Fabra University (UPF), as well as other seconded staff members from the Centre for Research in Environmental Epidemiology (CREAL), the Centre for Genomic Regulation (CRG), the Department of Experimental and Health Sciences of the Pompeu Fabra University (DCEXS-UPF), the Centre of Regenerative Medicine in Barcelona (CMRB) and the Barcelona Biomedical Research Park (PRBB).

On 16 December 2013, the Accreditation Committee of the Carlos III Health Institute (ISCIII) approved the acreditation of IMIM as a Health Research Institute, which was ratified by the State Secretarial of Research, Development and Innovation for the Order of 17 February 2014.

At IMIM there are around seven hundred professionals, of which one hundred and nineteen are lead researchers distributed in fifty-six research groups integrated into the five multi-disciplinary programmes framing research activities within IMIM:

Cancer, directed by Joan Albanell
Epidemiology and Public Health, directed by Jordi Alonso
Cardiovascular and inflammatory processes, directed by Miguel López-Botet
Biomedical Informatics, directed by Ferran Sanz
Neurosciences, directed by Rafael de la Torre

A large proportion of its budget is provided by external competitive funds that are managed by the Mar Institute of Medical Research Foundation.

The scientific output generate from this research includes almost 550 annual papers in international journals indexed in the Science Citation Index (SCI). Another relevant fact is that 65% of the IMIM papers are published in journals that are in the top quartile of their category.

IMIM has a Scientific Advisory Board (SAB) made up of a group of prestigious international expert scientists from the different areas of the IMIM research programmes.

IMIM Institut Recerca Hospital del Mar

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